Bus Madrid to Karlsruhe: Compare prices and save money

Compare all timetables for the bus from Madrid to Karlsruhe

Here is a selection of the cheapest bus trips from the schedule from Madrid to Karlsruhe from various bus operators like FlixBus or BlaBlaCar Bus for the next days.

today

$125

tomorrow

Tuesday

$88

Wednesday

Thursday

Friday

$129

Saturday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 55m	9:55 PM	Madrid	Sur Bus Station	1:50 AM	Karlsruhe	Central Station	Economy	$125	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/19/2026 9:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/21/2026 1:50:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 27h 55m
FlixBus	25h 25m	4:40 PM	Madrid	Sur Bus Station	6:05 PM	Karlsruhe	Central Station	Economy	$143	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/19/2026 4:40:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/20/2026 6:05:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 25h 25m
FlixBus	30h 10m	11:35 PM	Madrid	Sur Bus Station	5:45 AM	Karlsruhe	Central Station	Economy	$161	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/19/2026 11:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/21/2026 5:45:00 AM. 50 Economy ticket for $161 per person are available. Travel duration is 30h 10m
FlixBus	27h 35m	8:25 PM	Madrid	Sur Bus Station	12:00 AM	Karlsruhe	Central Station	Economy	$164	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/19/2026 8:25:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/21/2026 12:00:00 AM. 50 Economy ticket for $164 per person are available. Travel duration is 27h 35m

Did you know that if you travel from Madrid to Karlsruhe via Lyon, you can save more than $24? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  29h 5m
  
  0
  
  6:30 AM
  
  Madrid
  Sur Bus Station
  
  1:10 AM
  
  Lyon
  Perrache Train Station
  
  0
  
  Economy
  
  $70
  
  A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 7/20/2026 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 7/21/2026 1:10:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 18h 40m
- BlaBlaCar Bus
  
  8h 15m
  
  0
  
  3:20 AM
  
  Lyon
  Perrache Train Station
  
  11:35 AM
  
  Karlsruhe
  Central Station
  
  0
  
  Economy
  
  $31
  
  A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/21/2026 3:20:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/21/2026 11:35:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 8h 15m
Travel time is 3h 40m longer, but you will save $24

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	28h 35m	10:30 PM	Madrid	Sur Bus Station	3:05 AM	Karlsruhe	Central Station	Economy	$88	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 7/21/2026 10:30:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/23/2026 3:05:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 28h 35m
FlixBus	26h 10m	3:55 PM	Madrid	Sur Bus Station	6:05 PM	Karlsruhe	Central Station	Economy	$102	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/21/2026 3:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/22/2026 6:05:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 26h 10m
FlixBus	27h 55m	9:55 PM	Madrid	Sur Bus Station	1:50 AM	Karlsruhe	Central Station	Economy	$102	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/21/2026 9:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/23/2026 1:50:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 27h 55m
FlixBus	30h 10m	11:35 PM	Madrid	Sur Bus Station	5:45 AM	Karlsruhe	Central Station	Economy	$104	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/21/2026 11:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/23/2026 5:45:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 30h 10m

Did you know that if you travel from Madrid to Karlsruhe via Lyon, you can save more than $17? You can find the corresponding connections below.
- FlixBus
  
  38h 45m
  
  0
  
  8:50 PM
  
  Madrid
  Sur Bus Station
  
  1:30 PM
  
  Lyon
  Lyon Avenue Tony Garnier Bus Stop
  
  0
  
  Economy
  
  $40
  
  A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/22/2026 8:50:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/23/2026 1:30:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 16h 40m
- BlaBlaCar Bus
  
  8h 15m
  
  0
  
  3:20 AM
  
  Lyon
  Perrache Train Station
  
  11:35 AM
  
  Karlsruhe
  Central Station
  
  0
  
  Economy
  
  $31
  
  A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/24/2026 3:20:00 AM to Central Station, Karlsruhe (Germany) arriving at 7/24/2026 11:35:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 8h 15m
Travel time is 12h 35m longer, but you will save $17

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 55m	9:55 PM	Madrid	Sur Bus Station	1:50 AM	Karlsruhe	Central Station	Economy	$129	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/24/2026 9:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/26/2026 1:50:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 27h 55m
FlixBus	25h 25m	4:40 PM	Madrid	Sur Bus Station	6:05 PM	Karlsruhe	Central Station	Economy	$135	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/24/2026 4:40:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/25/2026 6:05:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 25h 25m
FlixBus	30h 10m	11:35 PM	Madrid	Sur Bus Station	5:45 AM	Karlsruhe	Central Station	Economy	$142	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/24/2026 11:35:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/26/2026 5:45:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 30h 10m
FlixBus	26h 10m	3:55 PM	Madrid	Sur Bus Station	6:05 PM	Karlsruhe	Central Station	Economy	$148	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/24/2026 3:55:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/25/2026 6:05:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 26h 10m

Did you know that if you travel from Madrid to Karlsruhe via Lyon, you can save more than $55? You can find the corresponding connections below.
- FlixBus
  
  29h 0m
  
  0
  
  8:50 PM
  
  Madrid
  Sur Bus Station
  
  1:30 PM
  
  Lyon
  Lyon Avenue Tony Garnier Bus Stop
  
  0
  
  Economy
  
  $40
  
  A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 7/22/2026 8:50:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 7/23/2026 1:30:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 16h 40m
- FlixBus
  
  8h 45m
  
  0
  
  5:05 PM
  
  Lyon
  Lyon Avenue Tony Garnier Bus Stop
  
  1:50 AM
  
  Karlsruhe
  Central Station
  
  0
  
  Economy
  
  $34
  
  A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 7/23/2026 5:05:00 PM to Central Station, Karlsruhe (Germany) arriving at 7/24/2026 1:50:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 45m
Travel time is 3h 35m longer, but you will save $55

Best Price Offer: The price for the cheapest bus from Madrid to Karlsruhe is $88 on 7/21/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Madrid and Karlsruhe

See here how frequent the connections between Madrid and Karlsruhe are, during different times and days of the week.

Tuesday is the busiest day, with more than 6 daily buses from Madrid to Karlsruhe. Sunday has instead the fewest connections, with only 4 daily coaches between Madrid and Karlsruhe.

The busiest time of the day is the Evening, with 9 buses from Madrid to Karlsruhe, while Afternoon sees the fewest connections between Madrid and Karlsruhe, with 5 offers.

Facts about the bus from Madrid to Karlsruhe

Compare all providers like FlixBus and BlaBlaCar Bus that travel 4 times every day by bus from Madrid to Karlsruhe in one click! Book your bus ticket from Madrid to Karlsruhe starting from $88!

Cheapest Bus	$88
Fastest Bus	25h 25m
Earliest Bus	4:40 PM
Latest Bus	11:35 PM
Daily Bus Routes	4 Ø
Distance	838.4 miles
Bus Companies	FlixBus and BlaBlaCar Bus

Cheapest bus connections from Madrid to Karlsruhe

Every day, 4 buses from 2 bus companies leave Madrid for Karlsruhe: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

$125

Monday 07/20

Tuesday 07/21

$102

Wednesday 07/22

Thursday 07/23

Friday 07/24

$129

Saturday 07/25

Sunday 07/26

$128

Monday 07/27

Tuesday 07/28

Wednesday 07/29

$92

Thursday 07/30

Friday 07/31

Saturday 08/01

Sunday 08/02

$130

Monday 08/03

$97

Tuesday 08/04

Wednesday 08/05

Thursday 08/06

Friday 08/07

$128

Saturday 08/08

$112

Sunday 08/09

$101

Monday 08/10

$112

Tuesday 08/11

$105

Wednesday 08/12

Thursday 08/13

Friday 08/14

Saturday 08/15

The cheapest time to travel from Madrid to Karlsruhe

See here on which day and which time of the day you can find the cheapest bus ticket from Madrid to Karlsruhe, for the next 30 days.

With a price starting from $88, Tuesday is the cheapest day for a bus from Madrid to Karlsruhe. Friday instead is the most expensive day with prices starting from $128.

Evening is the cheapest day time for bus tickets from Madrid to Karlsruhe, with $88. Afternoon is the most expensive time of the day with prices starting from $102.

How to save money travelling from Madrid to Karlsruhe

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madrid to Karlsruhe in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Karlsruhe, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madrid to Karlsruhe are also emptier.

All bus stations and stops in Madrid and Karlsruhe

In the map below, you can see where to find all bus stations in Madrid and Karlsruhe.

Avenida de América Bus Station

Avenida de América 13

Bus Stop

Calle de Tiziano 40

Intercambiador de Moncloa

Calle de la Princesa 89n

Plaza de Castilla

Sur Bus Station

Calle de Méndez Álvaro 83

Central Bus Station

Durlach Auer Str./Dr.Willmar Schwabe Bus Stop

Bannwaldallee Station

Kühler Krug Train Station

Sudetenstraße Bus Stop

Service and Comfort on the bus from Madrid to Karlsruhe

Want to know which seat classes are available on the buses from Madrid to Karlsruhe? Or which bus companies serve the route Madrid to Karlsruhe? Below you will find answers to your questions.

FAQs about the Madrid to Karlsruhe bus

How much does a Madrid Karlsruhe bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $88 and takes 28h 35m to reach Karlsruhe. Compare offers to save money!

How much could I save by comparing buses from Madrid to Karlsruhe?

This route is offered by 2 companies with a range of ticket prices between $88 and $164. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Karlsruhe.

On average, how many connections are available from Madrid to Karlsruhe each day?

Every day, the Madrid to Karlsruhe bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Madrid to Karlsruhe take?

The fastest bus from Madrid to Karlsruhe is offered by FlixBus and takes 25h 25m. Bus tickets for this connection cost $143. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Madrid to Karlsruhe?

The earliest bus arriving in Karlsruhe from Madrid starts at 4:40 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Madrid to Karlsruhe?

The latest bus trip departing from Madrid for Karlsruhe starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Madrid Karlsruhe route?

When traveling by bus from Madrid to Karlsruhe, passengers can travel with FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Madrid and Karlsruhe?

You can check all the direct connections between Madrid and Karlsruhe by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the Madrid to Karlsruhe bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Madrid Karlsruhe bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Madrid Karlsruhe bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madrid to Karlsruhe on your planned travel date.

How does CheckMyBus find the best bus deals from Madrid to Karlsruhe?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Madrid and Karlsruhe. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Madrid to Karlsruhe?

Prices and availability for 4 trips between Madrid and Karlsruhe change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Madrid to Karlsruhe

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madrid and to Karlsruhe

Here’s an overview of the most popular bus routes to Madrid and to Karlsruhe. Simply click on the connection of your choice, and you will find all the details about your bus route!