What is the best way to travel from Lyon to Madrid?
Looking for a trip? Compare all the available Buses, Trains and Flights for the journey to Madrid from Lyon. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 5 available companies to find your perfect trip!
What is the cheapest way to reach Madrid from Lyon?
You can get to Madrid with just $58 by taking a Bus from Union Ivkoni, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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ALSA16h 55m05:10 AMLyonPerrache Bus Stop10:05 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 5:10:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 12/5/2025 10:05:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 16h 55m
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BlaBlaCar Bus22h 25m04:45 PMLyonPerrache Train Station3:10 PMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/5/2025 4:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/6/2025 3:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 22h 25m
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Union Ivkoni22h 45m02:15 PMLyonPerrache Bus Stop1:00 PMMadridMendez Alvaro Train Station0BasicA Bus from Union Ivkoni goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 2:15:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 12/6/2025 1:00:00 PM. 50 Basic ticket for $86 per person are available. Travel duration is 22h 45m
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BlaBlaCar Bus19h 25m05:15 AMLyonPerrache Train Station12:40 AMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/5/2025 5:15:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/6/2025 12:40:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 19h 25m
Cheapest Buses Friday
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BlaBlaCar Bus22h 25m04:45 PMLyonPerrache Train Station3:10 PMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/6/2025 4:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/7/2025 3:10:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 22h 25m
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BlaBlaCar Bus19h 25m05:15 AMLyonPerrache Train Station12:40 AMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/6/2025 5:15:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/7/2025 12:40:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 19h 25m
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ALSA19h 30m08:30 PMLyonPerrache Bus Stop4:00 PMMadridMendez Alvaro Train Station0EconomyA Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 8:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 12/7/2025 4:00:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 19h 30m
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FlixBus16h 40m04:00 PMLyonPerrache Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/7/2025 8:40:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 16h 40m
Cheapest Buses Saturday
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BlaBlaCar Bus20h 0m04:40 AMLyonPerrache Train Station12:40 AMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/7/2025 4:40:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/8/2025 12:40:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 20h 0m
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BlaBlaCar Bus17h 15m08:50 PMLyonPerrache Train Station2:05 PMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/7/2025 8:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/8/2025 2:05:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 17h 15m
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BlaBlaCar Bus22h 25m04:45 PMLyonPerrache Train Station3:10 PMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/7/2025 4:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/8/2025 3:10:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 22h 25m
Cheapest Buses Sunday
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FlixBus16h 40m04:00 PMLyonPerrache Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/8/2025 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/9/2025 8:40:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 16h 40m
Cheapest Buses Monday
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FlixBus16h 40m04:00 PMLyonPerrache Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/10/2025 8:40:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 16h 40m
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FlixBus19h 0m03:15 PMLyonPerrache Bus Stop10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 3:15:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/10/2025 10:15:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 19h 0m
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FlixBus22h 35m011:40 AMLyonPerrache Bus Stop10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 11:40:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/10/2025 10:15:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 22h 35m
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FlixBus19h 50m02:25 PMLyonPerrache Bus Stop10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 2:25:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/10/2025 10:15:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 19h 50m
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LC Perú29h 5m02:55 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:00 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/9/2025 2:55:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/10/2025 8:00:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 29h 5m
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Skyscanner5h 10m06:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:30 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/9/2025 6:20:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/9/2025 11:30:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 5h 10m
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Vueling Airlines4h 50m08:15 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station1:05 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/9/2025 8:15:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/9/2025 1:05:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 4h 50m
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EasyJet Airline4h 55m05:25 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:20 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/9/2025 5:25:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/9/2025 10:20:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 4h 55m
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Renfe9h 12m02:35 PMLyonPart-Dieu Train Station11:47 PMMadridAtocha Train Station0EconomyA Train from Renfe goes from Part-Dieu Train Station, Lyon (France) at 12/9/2025 2:35:00 PM to Atocha Train Station, Madrid (Spain) arriving at 12/9/2025 11:47:00 PM. 50 Economy ticket for $198 per person are available. Travel duration is 9h 12m
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Renfe9h 23m02:35 PMLyonPart-Dieu Train Station11:58 PMMadridAtocha Train Station0EconomyA Train from Renfe goes from Part-Dieu Train Station, Lyon (France) at 12/9/2025 2:35:00 PM to Atocha Train Station, Madrid (Spain) arriving at 12/9/2025 11:58:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 9h 23m
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Renfe8h 44m02:35 PMLyonPart-Dieu Train Station11:19 PMMadridAtocha Train Station0EconomyA Train from Renfe goes from Part-Dieu Train Station, Lyon (France) at 12/9/2025 2:35:00 PM to Atocha Train Station, Madrid (Spain) arriving at 12/9/2025 11:19:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 8h 44m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
Cheapest Trains Tuesday
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Union Ivkoni23h 0m02:15 PMLyonPerrache Bus Stop1:15 PMMadridMendez Alvaro Train Station0BasicA Bus from Union Ivkoni goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 2:15:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 12/11/2025 1:15:00 PM. 50 Basic ticket for $58 per person are available. Travel duration is 23h 0m
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FlixBus16h 40m04:00 PMLyonPerrache Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/11/2025 8:40:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 16h 40m
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FlixBus25h 10m07:30 AMLyons St. Exupery AirportLyons St. Exupery Airport8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 12/10/2025 7:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/11/2025 8:40:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 25h 10m
Cheapest Buses Wednesday
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ALSA19h 30m08:30 PMLyonPerrache Bus Stop4:00 PMMadridMendez Alvaro Train Station0EconomyA Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 12/11/2025 8:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 12/12/2025 4:00:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 19h 30m
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FlixBus16h 40m04:00 PMLyonPerrache Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/11/2025 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/12/2025 8:40:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 40m
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FlixBus20h 15m02:00 PMLyonPerrache Bus Stop10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/11/2025 2:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/12/2025 10:15:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 20h 15m
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FlixBus19h 0m03:15 PMLyonPerrache Bus Stop10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/11/2025 3:15:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/12/2025 10:15:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 19h 0m
Cheapest Buses Thursday
What are the fastest trips from Lyon to Madrid?
You can get to Madrid from Lyon in just 4h 50m with a Flight from Vueling Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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ALSA16h 55m05:10 AMLyonPerrache Bus Stop10:05 PMMadridAvenida de América Bus Station0EconomyA Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 5:10:00 AM to Avenida de América Bus Station, Madrid (Spain) arriving at 12/5/2025 10:05:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 16h 55m
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BlaBlaCar Bus19h 25m05:15 AMLyonPerrache Train Station12:40 AMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/5/2025 5:15:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/6/2025 12:40:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 19h 25m
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FlixBus20h 30m02:00 PMLyons St. Exupery AirportLyons St. Exupery Airport10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 12/5/2025 2:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/6/2025 10:30:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 20h 30m
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BlaBlaCar Bus22h 25m04:45 PMLyonPerrache Train Station3:10 PMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/5/2025 4:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/6/2025 3:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 22h 25m
Fastest Buses Friday
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FlixBus16h 40m04:00 PMLyonPerrache Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/7/2025 8:40:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 16h 40m
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BlaBlaCar Bus19h 25m05:15 AMLyonPerrache Train Station12:40 AMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/6/2025 5:15:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/7/2025 12:40:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 19h 25m
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ALSA19h 30m08:30 PMLyonPerrache Bus Stop4:00 PMMadridMendez Alvaro Train Station0EconomyA Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 8:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 12/7/2025 4:00:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 19h 30m
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FlixBus22h 10m010:30 AMLyons St. Exupery AirportLyons St. Exupery Airport8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 12/6/2025 10:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/7/2025 8:40:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 22h 10m
Fastest Buses Saturday
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BlaBlaCar Bus17h 15m08:50 PMLyonPerrache Train Station2:05 PMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/7/2025 8:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/8/2025 2:05:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 17h 15m
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BlaBlaCar Bus20h 0m04:40 AMLyonPerrache Train Station12:40 AMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/7/2025 4:40:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/8/2025 12:40:00 AM. 50 Economy ticket for $91 per person are available. Travel duration is 20h 0m
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BlaBlaCar Bus22h 25m04:45 PMLyonPerrache Train Station3:10 PMMadridSur Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/7/2025 4:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/8/2025 3:10:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 22h 25m
Fastest Buses Sunday
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FlixBus16h 40m04:00 PMLyonPerrache Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/8/2025 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/9/2025 8:40:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 16h 40m
Fastest Buses Monday
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Vueling Airlines4h 50m08:15 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station1:05 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/9/2025 8:15:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/9/2025 1:05:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 4h 50m
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EasyJet Airline4h 55m05:25 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:20 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/9/2025 5:25:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/9/2025 10:20:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 4h 55m
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Skyscanner5h 10m06:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:30 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/9/2025 6:20:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/9/2025 11:30:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 5h 10m
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KLM - Royal Dutch Airlines20h 5m02:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from KLM - Royal Dutch Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/9/2025 2:10:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/10/2025 10:15:00 AM. 50 Economy ticket for $183 per person are available. Travel duration is 20h 5m
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Renfe8h 44m02:35 PMLyonPart-Dieu Train Station11:19 PMMadridAtocha Train Station0EconomyA Train from Renfe goes from Part-Dieu Train Station, Lyon (France) at 12/9/2025 2:35:00 PM to Atocha Train Station, Madrid (Spain) arriving at 12/9/2025 11:19:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 8h 44m
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Renfe9h 12m02:35 PMLyonPart-Dieu Train Station11:47 PMMadridAtocha Train Station0EconomyA Train from Renfe goes from Part-Dieu Train Station, Lyon (France) at 12/9/2025 2:35:00 PM to Atocha Train Station, Madrid (Spain) arriving at 12/9/2025 11:47:00 PM. 50 Economy ticket for $198 per person are available. Travel duration is 9h 12m
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Renfe9h 23m02:35 PMLyonPart-Dieu Train Station11:58 PMMadridAtocha Train Station0EconomyA Train from Renfe goes from Part-Dieu Train Station, Lyon (France) at 12/9/2025 2:35:00 PM to Atocha Train Station, Madrid (Spain) arriving at 12/9/2025 11:58:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 9h 23m
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FlixBus16h 40m04:00 PMLyonPerrache Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/10/2025 8:40:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 16h 40m
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FlixBus19h 0m03:15 PMLyonPerrache Bus Stop10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 3:15:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/10/2025 10:15:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 19h 0m
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FlixBus19h 50m02:25 PMLyonPerrache Bus Stop10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 2:25:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/10/2025 10:15:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 19h 50m
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FlixBus22h 35m011:40 AMLyonPerrache Bus Stop10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 11:40:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/10/2025 10:15:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 22h 35m
Fastest Flights Tuesday
Fastest Trains Tuesday
Fastest Buses Tuesday
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FlixBus16h 40m04:00 PMLyonPerrache Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/11/2025 8:40:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 16h 40m
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Union Ivkoni23h 0m02:15 PMLyonPerrache Bus Stop1:15 PMMadridMendez Alvaro Train Station0BasicA Bus from Union Ivkoni goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 2:15:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 12/11/2025 1:15:00 PM. 50 Basic ticket for $58 per person are available. Travel duration is 23h 0m
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FlixBus25h 10m07:30 AMLyons St. Exupery AirportLyons St. Exupery Airport8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 12/10/2025 7:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/11/2025 8:40:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 25h 10m
Fastest Buses Wednesday
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FlixBus16h 40m04:00 PMLyonPerrache Bus Stop8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/11/2025 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/12/2025 8:40:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 40m
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FlixBus19h 0m03:15 PMLyonPerrache Bus Stop10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/11/2025 3:15:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/12/2025 10:15:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 19h 0m
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ALSA19h 30m08:30 PMLyonPerrache Bus Stop4:00 PMMadridMendez Alvaro Train Station0EconomyA Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 12/11/2025 8:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 12/12/2025 4:00:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 19h 30m
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FlixBus20h 15m02:00 PMLyonPerrache Bus Stop10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/11/2025 2:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/12/2025 10:15:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 20h 15m
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Lyon to Madrid
What are the most popular stations in Lyon and Madrid?
In Lyon, you will usually depart from Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, while in Madrid you will be arriving at Atocha Train Station, Chamartin Train Station or Sur Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Madrid from Lyon? With 4 connections between 5 Bus, Train and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Madrid, you can pay as low as $58 with a Bus from Union Ivkoni.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Vueling Airlines: you will get to Madrid in just 4h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Madrid are FlixBus, BlaBlaCar Bus and ALSA, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Madrid is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Delicias, and look at flights from Lyons St. Exupery Airport, and landing at Adolfo Suárez Madrid-Barajas Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Madrid?
The most popular companies between Lyon and Madrid, are FlixBus, BlaBlaCar Bus and ALSA. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, BlaBlaCar Bus, ALSA and 1 more.
Train companies: Renfe
Airlines: LC Perú, Skyscanner, Vueling Airlines and 2 more.
All you need to know when you travel from Lyon to Madrid
Check all information on comfort and services on all modes of transports from Lyon to Madrid. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Madrid
How can I reach Madrid from Lyon?
Every day, there are on average 4 connections between Bus, Train and Flight, with which you can get to Madrid from Lyon.
How far is Madrid from Lyon?
The distance between Lyon and Madrid is 566.9 miles.
What is the most ecofriendly mode of transport between Lyon and Madrid?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 155 kgs, and a flight 224 kgs.
What is the cheapest mode of transport from Lyon to Madrid?
You can get to Madrid with just $58 by taking a Bus from Union Ivkoni.
What is the fastest way to get from Lyon to Madrid?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Madrid in just 4h 50m with a Flight from Vueling Airlines.
More routes to Lyon and to Madrid
Looking for more options? Here you can see the most popular routes to Lyon and to Madrid. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Avignon to Lyon
- Barcelona to Lyon
- Basel to Lyon
- Bordeaux to Lyon
- Caen to Lyon
- Dijon to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Lisbon to Lyon
- Lloret de Mar to Lyon
- London to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille to Lyon
- Milan to Lyon
- Nancy to Lyon
- Paris to Lyon
- Rome to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Venice to Lyon
- Trips to Madrid
- Almería to Madrid
- Badajoz to Madrid
- Barcelona to Madrid
- Bordeaux to Madrid
- Cuenca to Madrid
- Granada to Madrid
- Guadalajara to Madrid
- Jaén to Madrid
- Lisbon to Madrid
- Lleida to Madrid
- Malaga to Madrid
- Milan to Madrid
- Molina de Aragón to Madrid
- Navalmoral de la Mata to Madrid
- Oropesa del Mar to Madrid
- Paris to Madrid
- Pontevedra to Madrid
- Porto Airport to Madrid
- Porto to Madrid
- Segovia to Madrid
- Talavera de la Reina to Madrid
- Toledo (ES) to Madrid
- Valencia to Madrid
- Vigo to Madrid

