Compare all timetables for the bus from Lyon to Madrid
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 16h 40m | 4:30 PM | Lyon | Perrache Bus Stop | 9:10 AM | Madrid | Mendez Alvaro Train Station | Economy | $50 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 3/21/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/22/2026 9:10:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 16h 40m
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| ALSA | 17h 55m | 10:50 PM | Lyon | Perrache Bus Stop | 4:45 PM | Madrid | Mendez Alvaro Train Station | Economy | $62 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 3/21/2026 10:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/22/2026 4:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 17h 55m
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| FlixBus | 17h 35m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:25 PM | Madrid | Sur Bus Station | Economy | $67 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/21/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/22/2026 3:25:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 17h 35m
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| FlixBus | 16h 40m | 4:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:40 AM | Madrid | Sur Bus Station | Economy | $74 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/21/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/22/2026 8:40:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 16h 40m
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| BlaBlaCar Bus | 19h 45m | 2:00 PM | Lyon | Perrache Train Station | 9:45 AM | Madrid | Sur Bus Station | Economy | $133 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 3/21/2026 2:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/22/2026 9:45:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 19h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 16h 40m | 4:30 PM | Lyon | Perrache Bus Stop | 9:10 AM | Madrid | Mendez Alvaro Train Station | Economy | $50 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 3/22/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/23/2026 9:10:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 16h 40m
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| ALSA | 17h 15m | 8:50 PM | Lyon | Perrache Bus Stop | 2:05 PM | Madrid | Mendez Alvaro Train Station | Economy | $62 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 3/22/2026 8:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/23/2026 2:05:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 17h 15m
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| Union Ivkoni | 22h 15m | 3:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 1:15 PM | Madrid | Mendez Alvaro Train Station | Basic | $64 |
A Bus from Union Ivkoni goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/22/2026 3:00:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/23/2026 1:15:00 PM. 50 Basic ticket for $64 per person are available. Travel duration is 22h 15m
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| FlixBus | 17h 35m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:25 PM | Madrid | Sur Bus Station | Economy | $66 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/22/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/23/2026 3:25:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 17h 35m
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| BlaBlaCar Bus | 17h 10m | 8:55 PM | Lyon | Perrache Train Station | 2:05 PM | Madrid | Sur Bus Station | Economy | $69 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 3/22/2026 8:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/23/2026 2:05:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 17h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 16h 40m | 4:30 PM | Lyon | Perrache Bus Stop | 9:10 AM | Madrid | Mendez Alvaro Train Station | Economy | $51 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 3/23/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/24/2026 9:10:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 16h 40m
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| FlixBus | 17h 35m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:25 PM | Madrid | Sur Bus Station | Economy | $66 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/23/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/24/2026 3:25:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 17h 35m
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| FlixBus | 22h 35m | 9:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 7:55 AM | Madrid | Sur Bus Station | Economy | $72 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/23/2026 9:20:00 AM to Sur Bus Station, Madrid (Spain) arriving at 3/24/2026 7:55:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 22h 35m
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| BlaBlaCar Bus | 19h 45m | 2:00 PM | Lyon | Perrache Train Station | 9:45 AM | Madrid | Sur Bus Station | Economy | $86 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 3/23/2026 2:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/24/2026 9:45:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 19h 45m
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| BlaBlaCar Bus | 19h 20m | 5:20 AM | Lyon | Perrache Train Station | 12:40 AM | Madrid | Sur Bus Station | Economy | $127 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 3/23/2026 5:20:00 AM to Sur Bus Station, Madrid (Spain) arriving at 3/24/2026 12:40:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 19h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 35m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:25 PM | Madrid | Sur Bus Station | Economy | $58 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/24/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/25/2026 3:25:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 17h 35m
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| FlixBus | 22h 35m | 9:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 7:55 AM | Madrid | Sur Bus Station | Economy | $69 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/24/2026 9:20:00 AM to Sur Bus Station, Madrid (Spain) arriving at 3/25/2026 7:55:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 22h 35m
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| FlixBus | 16h 40m | 4:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:40 AM | Madrid | Sur Bus Station | Economy | $72 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/24/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/25/2026 8:40:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 16h 40m
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| FlixBus | 22h 30m | 11:45 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 10:15 AM | Madrid | Sur Bus Station | Economy | $149 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/24/2026 11:45:00 AM to Sur Bus Station, Madrid (Spain) arriving at 3/25/2026 10:15:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 22h 30m
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| FlixBus | 19h 50m | 2:25 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 10:15 AM | Madrid | Sur Bus Station | Economy | $149 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/24/2026 2:25:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/25/2026 10:15:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 19h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 35m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:25 PM | Madrid | Sur Bus Station | Economy | $58 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/25/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/26/2026 3:25:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 17h 35m
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| BlaBlaCar Bus | 17h 10m | 8:55 PM | Lyon | Perrache Train Station | 2:05 PM | Madrid | Sur Bus Station | Economy | $61 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 3/25/2026 8:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/26/2026 2:05:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 17h 10m
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| Union Ivkoni | 23h 0m | 2:15 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 1:15 PM | Madrid | Mendez Alvaro Train Station | Basic | $64 |
A Bus from Union Ivkoni goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/25/2026 2:15:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/26/2026 1:15:00 PM. 50 Basic ticket for $64 per person are available. Travel duration is 23h 0m
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| ALSA | 17h 15m | 8:50 PM | Lyon | Perrache Bus Stop | 2:05 PM | Madrid | Mendez Alvaro Train Station | Economy | $64 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 3/25/2026 8:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/26/2026 2:05:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 17h 15m
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| FlixBus | 16h 40m | 4:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:40 AM | Madrid | Sur Bus Station | Economy | $72 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/25/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/26/2026 8:40:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 16h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 35m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:25 PM | Madrid | Sur Bus Station | Economy | $58 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/26/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/27/2026 3:25:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 17h 35m
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| ALSA | 17h 55m | 10:50 PM | Lyon | Perrache Bus Stop | 4:45 PM | Madrid | Mendez Alvaro Train Station | Economy | $62 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 3/26/2026 10:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/27/2026 4:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 17h 55m
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| FlixBus | 22h 35m | 9:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 7:55 AM | Madrid | Sur Bus Station | Economy | $71 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/26/2026 9:20:00 AM to Sur Bus Station, Madrid (Spain) arriving at 3/27/2026 7:55:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 22h 35m
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| FlixBus | 16h 40m | 4:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:40 AM | Madrid | Sur Bus Station | Economy | $86 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/26/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/27/2026 8:40:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 40m
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| ALSA | 20h 15m | 8:30 PM | Lyon | Perrache Bus Stop | 4:45 PM | Madrid | Mendez Alvaro Train Station | Economy | $126 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 3/26/2026 8:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/27/2026 4:45:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 20h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Union Ivkoni | 22h 45m | 2:15 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 1:00 PM | Madrid | Sur Bus Station | Basic | $46 |
A Bus from Union Ivkoni goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/27/2026 2:15:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/28/2026 1:00:00 PM. 50 Basic ticket for $46 per person are available. Travel duration is 22h 45m
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| ALSA | 16h 40m | 4:30 PM | Lyon | Perrache Bus Stop | 9:10 AM | Madrid | Mendez Alvaro Train Station | Economy | $50 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 3/27/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/28/2026 9:10:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 16h 40m
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| BlaBlaCar Bus | 17h 10m | 8:55 PM | Lyon | Perrache Train Station | 2:05 PM | Madrid | Sur Bus Station | Economy | $62 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 3/27/2026 8:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/28/2026 2:05:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 17h 10m
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| ALSA | 17h 15m | 8:50 PM | Lyon | Perrache Bus Stop | 2:05 PM | Madrid | Mendez Alvaro Train Station | Economy | $62 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 3/27/2026 8:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 3/28/2026 2:05:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 17h 15m
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| FlixBus | 17h 35m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:25 PM | Madrid | Sur Bus Station | Economy | $88 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 3/27/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 3/28/2026 3:25:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 17h 35m
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Best Price Offer: The price for the cheapest bus from Lyon to Madrid is $46 on 3/27/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Lyon and Madrid
Facts about the bus from Lyon to Madrid
Compare all providers like FlixBus, ALSA and BlaBlaCar Bus that travel 10 times every day by bus from Lyon to Madrid in one click! Book your bus ticket from Lyon to Madrid starting from $46!
| Cheapest Bus | $46 |
| Fastest Bus | 16h 20m |
| Earliest Bus | 5:20 AM |
| Latest Bus | 10:50 PM |
| Daily Bus Routes | 10 Ø |
| Distance | 566.9 miles |
| Bus Companies | FlixBus, ALSA, BlaBlaCar Bus, Union Ivkoni and Internorte Transportes |
Cheapest bus connections from Lyon to Madrid
Every day, 10 buses from 5 bus companies leave Lyon for Madrid: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/21/2026 and for the following days.
The cheapest time to travel from Lyon to Madrid
How to save money travelling from Lyon to Madrid
Book the ticket from Lyon to Madrid in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lyon to Madrid, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lyon to Madrid are also emptier.Beloved bus companies from Lyon to Madrid
FlixBus from Lyon to Madrid
Here you will find the key facts about the FlixBus bus route Lyon to Madrid:
| Cheapest Price | $58 |
| Fastest Bus | 16h 40m |
| Earliest Bus | 9:20 AM |
| Last Bus | 9:50 PM |
| Daily Connections | 4 Ø |
| Found on | 3/20/2026 |
Union Ivkoni from Lyon to Madrid
Here you will find the key facts about the Union Ivkoni bus route Lyon to Madrid:
| Cheapest Price | $46 |
| Fastest Bus | 22h 15m |
| Earliest Bus | 3:00 PM |
| Last Bus | 2:15 PM |
| Daily Connections | 1 Ø |
| Found on | 3/20/2026 |
Latest reviews for bus companies on the route Lyon - Madrid
All bus stations and stops in Lyon and Madrid
In the map below, you can see where to find all bus stations in Lyon and Madrid.
Compare the bus with other modes of transport
Service and Comfort on the bus from Lyon to Madrid
FAQs about the Lyon to Madrid bus
How much does a Lyon Madrid bus trip cost?
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On average, how many connections are available from Lyon to Madrid each day?
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What time is the last bus from Lyon to Madrid?
Which bus companies operate the Lyon Madrid route?
Is there a direct bus between Lyon and Madrid?
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What equipment is available for the Lyon Madrid bus route?
How does CheckMyBus find the best bus deals from Lyon to Madrid?
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Available seat classes which are offered on the bus route Lyon to Madrid
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Lyon and to Madrid
- Bus Routes to Lyon
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- Bayonne to Lyon bus
- Buses Bilbao to Lyon
- From Bourges to Lyon bus
- Buses Clermont-Ferrand to Lyon
- Bus to Lyon from Dijon
- Buses Grenoble to Lyon
- Buses Le Puy-en-Velay to Lyon
- Bus Lille to Lyon
- Bus Lisbon - Lyon
- London to Lyon bus
- Buses Marseille - Lyon
- Buses from Massy to Lyon
- Bus from Milan to Lyon
- Buses to Lyon from Montpellier
- Buses from Munich to Lyon
- Buses Nice to Lyon
- Buses Paris - Lyon
- Bus to Lyon from Prague
- Buses Saint-Étienne to Lyon
- Bus Routes to Madrid
- Bus Almería - Madrid
- Bus Amsterdam to Madrid
- Buses Astorga - Madrid
- Buses from Benidorm to Madrid
- Buses Bilbao to Madrid
- Buses to Madrid from Bucharest
- Buses to Madrid from Cáceres (ES)
- From Jaén to Madrid bus
- Buses La Linea de la Concepción - Madrid
- Bus Lisbon to Madrid
- Buses Lourdes - Madrid
- Buses Lugo - Madrid
- Buses to Madrid from Murcia
- Buses Oliva - Madrid
- Bus Ourense to Madrid
- Buses Santander to Madrid
- Bus Segovia to Madrid
- Bus to Madrid from Torremolinos
- Bus to Madrid from Torrevieja
- Bus from Valencia to Madrid
