Compare all timetables for the bus from Lyon to Madrid
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 25m | 4:30 PM | Lyon | Perrache Bus Stop | 9:55 AM | Madrid | Mendez Alvaro Train Station | Economy | $50 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 5/5/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/6/2026 9:55:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 17h 25m
|
||
| ALSA | 17h 55m | 10:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 4:45 PM | Madrid | Mendez Alvaro Train Station | Economy | $57 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/5/2026 10:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/6/2026 4:45:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 17h 55m
|
||
| FlixBus | 16h 40m | 4:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:40 AM | Madrid | Sur Bus Station | Economy | $72 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/5/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/6/2026 8:40:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 16h 40m
|
||
| FlixBus | 17h 45m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:35 PM | Madrid | Sur Bus Station | Economy | $75 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/5/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/6/2026 3:35:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 17h 45m
|
||
| FlixBus | 19h 50m | 2:25 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 10:15 AM | Madrid | Sur Bus Station | Economy | $134 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/5/2026 2:25:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/6/2026 10:15:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 19h 50m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 25m | 4:30 PM | Lyon | Perrache Bus Stop | 9:55 AM | Madrid | Mendez Alvaro Train Station | Economy | $50 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 5/6/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/7/2026 9:55:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 17h 25m
|
||
| ALSA | 17h 15m | 8:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 2:05 PM | Madrid | Mendez Alvaro Train Station | Economy | $57 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/6/2026 8:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/7/2026 2:05:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 17h 15m
|
||
| BlaBlaCar Bus | 17h 10m | 8:55 PM | Lyon | Perrache Train Station | 2:05 PM | Madrid | Sur Bus Station | Economy | $64 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 5/6/2026 8:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/7/2026 2:05:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 17h 10m
|
||
| FlixBus | 16h 40m | 4:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:40 AM | Madrid | Sur Bus Station | Economy | $72 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/6/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/7/2026 8:40:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 16h 40m
|
||
| FlixBus | 17h 45m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:35 PM | Madrid | Sur Bus Station | Economy | $84 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/6/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/7/2026 3:35:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 17h 45m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 55m | 10:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 4:45 PM | Madrid | Mendez Alvaro Train Station | Economy | $47 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/7/2026 10:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/8/2026 4:45:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 17h 55m
|
||
| FlixBus | 17h 45m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:35 PM | Madrid | Sur Bus Station | Economy | $98 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/7/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/8/2026 3:35:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 17h 45m
|
||
| FlixBus | 22h 35m | 9:20 AM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 7:55 AM | Madrid | Sur Bus Station | Economy | $140 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/7/2026 9:20:00 AM to Sur Bus Station, Madrid (Spain) arriving at 5/8/2026 7:55:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 22h 35m
|
||
| FlixBus | 16h 40m | 4:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:40 AM | Madrid | Sur Bus Station | Economy | $145 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/7/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/8/2026 8:40:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 16h 40m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 55m | 10:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 4:45 PM | Madrid | Sur Bus Station | Basic | $51 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/8/2026 10:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/9/2026 4:45:00 PM. 50 Basic ticket for $51 per person are available. Travel duration is 17h 55m
|
||
| ALSA | 17h 15m | 8:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 2:05 PM | Madrid | Sur Bus Station | Basic | $51 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/8/2026 8:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/9/2026 2:05:00 PM. 50 Basic ticket for $51 per person are available. Travel duration is 17h 15m
|
||
| BlaBlaCar Bus | 17h 25m | 4:30 PM | Lyon | Perrache Train Station | 9:55 AM | Madrid | Sur Bus Station | Economy | $70 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 5/8/2026 4:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/9/2026 9:55:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 17h 25m
|
||
| BlaBlaCar Bus | 17h 10m | 8:55 PM | Lyon | Perrache Train Station | 2:05 PM | Madrid | Sur Bus Station | Economy | $70 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 5/8/2026 8:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/9/2026 2:05:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 17h 10m
|
||
| Union Ivkoni | 19h 15m | 2:15 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 9:30 AM | Madrid | Mendez Alvaro Train Station | Basic | $76 |
A Bus from Union Ivkoni goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/8/2026 2:15:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/9/2026 9:30:00 AM. 50 Basic ticket for $76 per person are available. Travel duration is 19h 15m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 25m | 4:30 PM | Lyon | Perrache Bus Stop | 9:55 AM | Madrid | Mendez Alvaro Train Station | Economy | $52 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 5/9/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/10/2026 9:55:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 17h 25m
|
||
| ALSA | 17h 55m | 10:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 4:45 PM | Madrid | Mendez Alvaro Train Station | Economy | $57 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/9/2026 10:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/10/2026 4:45:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 17h 55m
|
||
| FlixBus | 16h 40m | 4:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:40 AM | Madrid | Sur Bus Station | Economy | $72 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/9/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/10/2026 8:40:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 16h 40m
|
||
| FlixBus | 17h 45m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:35 PM | Madrid | Sur Bus Station | Economy | $72 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/9/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/10/2026 3:35:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 17h 45m
|
||
| BlaBlaCar Bus | 19h 20m | 5:20 AM | Lyon | Perrache Train Station | 12:40 AM | Madrid | Sur Bus Station | Economy | $92 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 5/9/2026 5:20:00 AM to Sur Bus Station, Madrid (Spain) arriving at 5/10/2026 12:40:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 19h 20m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 17h 25m | 4:30 PM | Lyon | Perrache Train Station | 9:55 AM | Madrid | Sur Bus Station | Economy | $49 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 5/10/2026 4:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/11/2026 9:55:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 17h 25m
|
||
| ALSA | 17h 55m | 10:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 4:45 PM | Madrid | Mendez Alvaro Train Station | Economy | $57 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/10/2026 10:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/11/2026 4:45:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 17h 55m
|
||
| ALSA | 17h 15m | 8:50 PM | Lyon | Perrache Bus Stop | 2:05 PM | Madrid | Mendez Alvaro Train Station | Economy | $63 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 5/10/2026 8:50:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/11/2026 2:05:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 17h 15m
|
||
| BlaBlaCar Bus | 17h 10m | 8:55 PM | Lyon | Perrache Train Station | 2:05 PM | Madrid | Sur Bus Station | Economy | $70 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 5/10/2026 8:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/11/2026 2:05:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 17h 10m
|
||
| FlixBus | 17h 45m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:35 PM | Madrid | Sur Bus Station | Economy | $86 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/10/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/11/2026 3:35:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 17h 45m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 16h 40m | 4:30 PM | Lyon | Perrache Bus Stop | 9:10 AM | Madrid | Mendez Alvaro Train Station | Economy | $50 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 5/11/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/12/2026 9:10:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 16h 40m
|
||
| ALSA | 17h 25m | 4:30 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 9:55 AM | Madrid | Mendez Alvaro Train Station | Economy | $57 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/11/2026 4:30:00 PM to Mendez Alvaro Train Station, Madrid (Spain) arriving at 5/12/2026 9:55:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 17h 25m
|
||
| FlixBus | 16h 40m | 4:00 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 8:40 AM | Madrid | Sur Bus Station | Economy | $64 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/11/2026 4:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/12/2026 8:40:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 16h 40m
|
||
| FlixBus | 17h 45m | 9:50 PM | Lyon | Lyon Avenue Tony Garnier Bus Stop | 3:35 PM | Madrid | Sur Bus Station | Economy | $67 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Bus Stop, Lyon (France) at 5/11/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 5/12/2026 3:35:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 17h 45m
|
||
| BlaBlaCar Bus | 19h 20m | 5:20 AM | Lyon | Perrache Train Station | 12:40 AM | Madrid | Sur Bus Station | Economy | $92 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 5/11/2026 5:20:00 AM to Sur Bus Station, Madrid (Spain) arriving at 5/12/2026 12:40:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 19h 20m
|
Best Price Offer: The price for the cheapest bus from Lyon to Madrid is $47 on 5/27/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Lyon and Madrid
Facts about the bus from Lyon to Madrid
Compare all providers like FlixBus, ALSA and BlaBlaCar Bus that travel 12 times every day by bus from Lyon to Madrid in one click! Book your bus ticket from Lyon to Madrid starting from $47!
| Cheapest Bus | $47 |
| Fastest Bus | 16h 40m |
| Earliest Bus | 11:45 AM |
| Latest Bus | 9:50 PM |
| Daily Bus Routes | 12 Ø |
| Distance | 566.9 miles |
| Bus Companies | FlixBus, ALSA, BlaBlaCar Bus, Union Ivkoni and Internorte Transportes |
Cheapest bus connections from Lyon to Madrid
Every day, 12 buses from 5 bus companies leave Lyon for Madrid: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/05/2026 and for the following days.
The cheapest time to travel from Lyon to Madrid
How to save money travelling from Lyon to Madrid
Book the ticket from Lyon to Madrid in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lyon to Madrid, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lyon to Madrid are also emptier.Beloved bus companies from Lyon to Madrid
FlixBus from Lyon to Madrid
Here you will find the key facts about the FlixBus bus route Lyon to Madrid:
| Cheapest Price | $64 |
| Fastest Bus | 16h 40m |
| Earliest Bus | 11:45 AM |
| Last Bus | 9:50 PM |
| Daily Connections | 5 Ø |
| Found on | 5/5/2026 |
Union Ivkoni from Lyon to Madrid
Here you will find the key facts about the Union Ivkoni bus route Lyon to Madrid:
| Cheapest Price | $76 |
| Fastest Bus | 19h 15m |
| Earliest Bus | 2:15 PM |
| Last Bus | 3:00 PM |
| Daily Connections | 1 Ø |
| Found on | 5/5/2026 |
Latest reviews for bus companies on the route Lyon - Madrid
All bus stations and stops in Lyon and Madrid
In the map below, you can see where to find all bus stations in Lyon and Madrid.
Compare the bus with other modes of transport
Service and Comfort on the bus from Lyon to Madrid
FAQs about the Lyon to Madrid bus
How much does a Lyon Madrid bus trip cost?
How much could I save by comparing buses from Lyon to Madrid?
On average, how many connections are available from Lyon to Madrid each day?
How long does a bus journey from Lyon to Madrid take?
What time is the first bus from Lyon to Madrid?
What time is the last bus from Lyon to Madrid?
Which bus companies operate the Lyon Madrid route?
Is there a direct bus between Lyon and Madrid?
What can I take with me on the Lyon to Madrid bus route?
What equipment is available for the Lyon Madrid bus route?
How does CheckMyBus find the best bus deals from Lyon to Madrid?
How does CheckMyBus technology work for trips from Lyon to Madrid?
Available seat classes which are offered on the bus route Lyon to Madrid
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Lyon and to Madrid
- Bus Routes to Lyon
- Buses to Lyon from Berlin
- Brest to Lyon bus
- From Brive-la-Gaillarde to Lyon bus
- Bus Caen to Lyon
- From Chamonix to Lyon bus
- Buses Geneva - Lyon
- Bus Genoa to Lyon
- From Huez (Alpe d’Huez) to Lyon bus
- Bus Ljubljana to Lyon
- Buses to Lyon from Montpellier
- Buses to Lyon from Mulhouse
- Bus to Lyon from Nancy
- From Naples to Lyon bus
- From Perpignan to Lyon bus
- Bus from Poitiers to Lyon
- Bus Rennes - Lyon
- Buses Saint-Étienne to Lyon
- Buses from Tignes to Lyon
- Bus Turin to Lyon
- Buses to Lyon from Venice
- Bus Routes to Madrid
- Buses Algeciras - Madrid
- Bus Almería - Madrid
- Bus Amsterdam to Madrid
- Buses Ávila - Madrid
- Bus Badajoz - Madrid
- Buses from Benidorm to Madrid
- Buses Bilbao to Madrid
- Buses from Cuenca to Madrid
- Buses Estepona to Madrid
- From Évora to Madrid bus
- Buses from Fátima to Madrid
- Buses Granada to Madrid
- From Jaén to Madrid bus
- Bus from Lleida to Madrid
- Bus Paris to Madrid
- Bus Pontevedra to Madrid
- Bus San Sebastian to Madrid
- Bus to Madrid from Santiago de Compostela
- Bus Talavera de la Reina - Madrid
- Buses from Zamora to Madrid
