What is the best way to travel from Prague to Madrid?
Looking for a trip? Compare all the available Flights and Buses for the journey to Madrid from Prague. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Madrid from Prague?
You can get to Madrid with just $62 by taking a Flight from Wizz Air, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus36h 45m010:45 PMPrague AirportPrague Airport - T1/211:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/18/2026 10:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/20/2026 11:30:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 36h 45m
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FlixBus37h 40m011:40 PMPragueÚAN Florenc1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 10/18/2026 11:40:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/20/2026 1:20:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 37h 40m
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FlixBus37h 30m011:50 PMPragueWilsonova Bus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/18/2026 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/20/2026 1:20:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 37h 30m
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FlixBus34h 50m09:50 PMPragueNa Knížecí Station8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 10/18/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/20/2026 8:40:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 34h 50m
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FlixBus35h 15m09:25 PMPragueÚAN Florenc8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 10/18/2026 9:25:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/20/2026 8:40:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 35h 15m
Cheapest Buses Sunday
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FlixBus41h 30m04:45 PMPragueWilsonova Bus Station10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/19/2026 4:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 10:15:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 41h 30m
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FlixBus40h 45m05:30 PMPragueWilsonova Bus Station10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/19/2026 5:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 10:15:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 40h 45m
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FlixBus39h 30m06:45 PMPragueWilsonova Bus Station10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/19/2026 6:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 10:15:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 39h 30m
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FlixBus41h 45m05:45 PMPragueWilsonova Bus Station11:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/19/2026 5:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 11:30:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 41h 45m
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FlixBus44h 30m03:00 PMPragueČerný Most11:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 10/19/2026 3:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 11:30:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 44h 30m
Cheapest Buses Monday
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Wizz Air18h 5m05:35 PMPrague AirportPrague Airport11:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 10/20/2026 5:35:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/21/2026 11:40:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 18h 5m
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EasyJet Airline11h 20m09:50 PMPrague AirportPrague Airport9:10 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 10/20/2026 9:50:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/21/2026 9:10:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 11h 20m
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Eurowings13h 40m08:10 AMPrague AirportPrague Airport9:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Eurowings goes from Prague Airport, Prague Airport (Czech Republic) at 10/20/2026 8:10:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/20/2026 9:50:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 13h 40m
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Vueling Airlines9h 30m010:30 AMPrague AirportPrague Airport8:00 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 10/20/2026 10:30:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/20/2026 8:00:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 9h 30m
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Lufthansa9h 10m01:20 PMPrague AirportPrague Airport10:30 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Lufthansa goes from Prague Airport, Prague Airport (Czech Republic) at 10/20/2026 1:20:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/20/2026 10:30:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 9h 10m
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FlixBus37h 5m02:30 AMPragueWilsonova Bus Station3:35 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/20/2026 2:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 3:35:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 37h 5m
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FlixBus39h 25m05:30 PMPragueWilsonova Bus Station8:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/20/2026 5:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/22/2026 8:55:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 39h 25m
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FlixBus38h 10m06:45 PMPragueWilsonova Bus Station8:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/20/2026 6:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/22/2026 8:55:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 38h 10m
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FlixBus45h 55m011:00 AMPragueRoztyly8:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 10/20/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/22/2026 8:55:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 45h 55m
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FlixBus48h 5m03:30 PMPragueRoztyly3:35 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 10/20/2026 3:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/22/2026 3:35:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 48h 5m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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FlixBus37h 5m02:30 AMPragueWilsonova Bus Station3:35 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/22/2026 2:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/23/2026 3:35:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 37h 5m
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FlixBus41h 20m05:10 PMPragueRoztyly10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 10/22/2026 5:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/24/2026 10:30:00 AM. 50 Economy ticket for $156 per person are available. Travel duration is 41h 20m
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FlixBus39h 5m07:25 PMPragueZličín10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 10/22/2026 7:25:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/24/2026 10:30:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 39h 5m
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FlixBus48h 55m07:00 AMPrague AirportPrague Airport - T1/27:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/22/2026 7:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/24/2026 7:55:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 48h 55m
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FlixBus36h 45m010:45 PMPrague AirportPrague Airport - T1/211:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/22/2026 10:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/24/2026 11:30:00 AM. 50 Economy ticket for $169 per person are available. Travel duration is 36h 45m
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Sunexpress21h 5m09:40 PMPrague AirportPrague Airport6:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Sunexpress goes from Prague Airport, Prague Airport (Czech Republic) at 10/22/2026 9:40:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/23/2026 6:45:00 PM. 50 Economy ticket for $249 per person are available. Travel duration is 21h 5m
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Smartwings25h 30m06:00 AMPrague AirportPrague Airport7:30 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 10/22/2026 6:00:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/23/2026 7:30:00 AM. 50 Economy ticket for $261 per person are available. Travel duration is 25h 30m
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Bulgaria Air8h 15m011:55 AMPrague AirportPrague Airport8:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Bulgaria Air goes from Prague Airport, Prague Airport (Czech Republic) at 10/22/2026 11:55:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/22/2026 8:10:00 PM. 50 Economy ticket for $269 per person are available. Travel duration is 8h 15m
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Wizz Air11h 25m08:45 AMPrague AirportPrague Airport8:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 10/22/2026 8:45:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/22/2026 8:10:00 PM. 50 Economy ticket for $303 per person are available. Travel duration is 11h 25m
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Air Europa3h 10m09:55 AMPrague AirportPrague Airport1:05 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Air Europa goes from Prague Airport, Prague Airport (Czech Republic) at 10/22/2026 9:55:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/22/2026 1:05:00 PM. 50 Economy ticket for $319 per person are available. Travel duration is 3h 10m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus36h 45m010:45 PMPrague AirportPrague Airport - T1/210:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 10:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/25/2026 10:30:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 36h 45m
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FlixBus48h 55m07:00 AMPrague AirportPrague Airport - T1/26:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 7:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/25/2026 6:55:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 48h 55m
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FlixBus37h 50m06:50 PMPrague AirportPrague Airport - T1/27:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/25/2026 7:40:00 AM. 50 Economy ticket for $164 per person are available. Travel duration is 37h 50m
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Wizz Air7h 10m01:30 PMPrague AirportPrague Airport - T1/28:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 1:30:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/23/2026 8:40:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 7h 10m
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LOT Polish Airlines / Polskie Linie Lotnicze18h 55m07:40 PMPrague AirportPrague Airport - T1/22:35 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 7:40:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/24/2026 2:35:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 18h 55m
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Bulgaria Air26h 30m09:10 AMPrague AirportPrague Airport - T1/211:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Bulgaria Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 9:10:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/24/2026 11:40:00 AM. 50 Economy ticket for $189 per person are available. Travel duration is 26h 30m
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Air Serbia15h 5m08:35 PMPrague AirportPrague Airport - T1/211:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Serbia goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 8:35:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/24/2026 11:40:00 AM. 50 Economy ticket for $212 per person are available. Travel duration is 15h 5m
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Buzz5h 25m06:10 AMPrague AirportPrague Airport - T1/211:35 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 6:10:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/23/2026 11:35:00 AM. 50 Economy ticket for $213 per person are available. Travel duration is 5h 25m
Cheapest Buses Friday
Cheapest Flights Friday
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FlixBus37h 45m010:45 PMPrague AirportPrague Airport - T1/211:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/24/2026 10:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/26/2026 11:30:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 37h 45m
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FlixBus49h 55m07:00 AMPrague AirportPrague Airport - T1/27:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/24/2026 7:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/26/2026 7:55:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 49h 55m
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FlixBus38h 50m06:50 PMPrague AirportPrague Airport - T1/28:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/24/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/26/2026 8:40:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 38h 50m
Cheapest Buses Saturday
What are the fastest trips from Prague to Madrid?
You can get to Madrid from Prague in just 3h 10m with a Flight from Air Europa. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus34h 50m09:50 PMPragueNa Knížecí Station8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 10/18/2026 9:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/20/2026 8:40:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 34h 50m
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FlixBus35h 15m09:25 PMPragueÚAN Florenc8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 10/18/2026 9:25:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/20/2026 8:40:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 35h 15m
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FlixBus36h 45m010:45 PMPrague AirportPrague Airport - T1/211:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/18/2026 10:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/20/2026 11:30:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 36h 45m
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FlixBus37h 30m011:50 PMPragueWilsonova Bus Station1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/18/2026 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/20/2026 1:20:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 37h 30m
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FlixBus37h 40m011:40 PMPragueÚAN Florenc1:20 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 10/18/2026 11:40:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/20/2026 1:20:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 37h 40m
Fastest Buses Sunday
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FlixBus39h 30m06:45 PMPragueWilsonova Bus Station10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/19/2026 6:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 10:15:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 39h 30m
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FlixBus40h 45m05:30 PMPragueWilsonova Bus Station10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/19/2026 5:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 10:15:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 40h 45m
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FlixBus41h 30m04:45 PMPragueWilsonova Bus Station10:15 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/19/2026 4:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 10:15:00 AM. 50 Economy ticket for $126 per person are available. Travel duration is 41h 30m
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FlixBus41h 45m05:45 PMPragueWilsonova Bus Station11:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/19/2026 5:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 11:30:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 41h 45m
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FlixBus44h 30m03:00 PMPragueČerný Most11:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 10/19/2026 3:00:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 11:30:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 44h 30m
Fastest Buses Monday
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Lufthansa9h 10m01:20 PMPrague AirportPrague Airport10:30 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Lufthansa goes from Prague Airport, Prague Airport (Czech Republic) at 10/20/2026 1:20:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/20/2026 10:30:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 9h 10m
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Vueling Airlines9h 30m010:30 AMPrague AirportPrague Airport8:00 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 10/20/2026 10:30:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/20/2026 8:00:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 9h 30m
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EasyJet Airline11h 20m09:50 PMPrague AirportPrague Airport9:10 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 10/20/2026 9:50:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/21/2026 9:10:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 11h 20m
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Eurowings13h 40m08:10 AMPrague AirportPrague Airport9:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Eurowings goes from Prague Airport, Prague Airport (Czech Republic) at 10/20/2026 8:10:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/20/2026 9:50:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 13h 40m
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Wizz Air18h 5m05:35 PMPrague AirportPrague Airport11:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 10/20/2026 5:35:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/21/2026 11:40:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 18h 5m
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FlixBus37h 5m02:30 AMPragueWilsonova Bus Station3:35 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/20/2026 2:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/21/2026 3:35:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 37h 5m
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FlixBus38h 10m06:45 PMPragueWilsonova Bus Station8:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/20/2026 6:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/22/2026 8:55:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 38h 10m
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FlixBus39h 25m05:30 PMPragueWilsonova Bus Station8:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/20/2026 5:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/22/2026 8:55:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 39h 25m
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FlixBus45h 55m011:00 AMPragueRoztyly8:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 10/20/2026 11:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/22/2026 8:55:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 45h 55m
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FlixBus48h 5m03:30 PMPragueRoztyly3:35 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 10/20/2026 3:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/22/2026 3:35:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 48h 5m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Air Europa3h 10m09:55 AMPrague AirportPrague Airport1:05 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Air Europa goes from Prague Airport, Prague Airport (Czech Republic) at 10/22/2026 9:55:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/22/2026 1:05:00 PM. 50 Economy ticket for $319 per person are available. Travel duration is 3h 10m
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Bulgaria Air8h 15m011:55 AMPrague AirportPrague Airport8:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Bulgaria Air goes from Prague Airport, Prague Airport (Czech Republic) at 10/22/2026 11:55:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/22/2026 8:10:00 PM. 50 Economy ticket for $269 per person are available. Travel duration is 8h 15m
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Wizz Air11h 25m08:45 AMPrague AirportPrague Airport8:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 10/22/2026 8:45:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/22/2026 8:10:00 PM. 50 Economy ticket for $303 per person are available. Travel duration is 11h 25m
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Sunexpress21h 5m09:40 PMPrague AirportPrague Airport6:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Sunexpress goes from Prague Airport, Prague Airport (Czech Republic) at 10/22/2026 9:40:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/23/2026 6:45:00 PM. 50 Economy ticket for $249 per person are available. Travel duration is 21h 5m
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Smartwings25h 30m06:00 AMPrague AirportPrague Airport7:30 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 10/22/2026 6:00:00 AM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/23/2026 7:30:00 AM. 50 Economy ticket for $261 per person are available. Travel duration is 25h 30m
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FlixBus36h 45m010:45 PMPrague AirportPrague Airport - T1/211:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/22/2026 10:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/24/2026 11:30:00 AM. 50 Economy ticket for $169 per person are available. Travel duration is 36h 45m
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FlixBus37h 5m02:30 AMPragueWilsonova Bus Station3:35 PMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 10/22/2026 2:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/23/2026 3:35:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 37h 5m
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FlixBus39h 5m07:25 PMPragueZličín10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 10/22/2026 7:25:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/24/2026 10:30:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 39h 5m
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FlixBus41h 20m05:10 PMPragueRoztyly10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 10/22/2026 5:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/24/2026 10:30:00 AM. 50 Economy ticket for $156 per person are available. Travel duration is 41h 20m
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FlixBus48h 55m07:00 AMPrague AirportPrague Airport - T1/27:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/22/2026 7:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/24/2026 7:55:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 48h 55m
Fastest Flights Thursday
Fastest Buses Thursday
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Buzz5h 25m06:10 AMPrague AirportPrague Airport - T1/211:35 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 6:10:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/23/2026 11:35:00 AM. 50 Economy ticket for $213 per person are available. Travel duration is 5h 25m
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Wizz Air7h 10m01:30 PMPrague AirportPrague Airport - T1/28:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 1:30:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/23/2026 8:40:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 7h 10m
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Air Serbia15h 5m08:35 PMPrague AirportPrague Airport - T1/211:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Serbia goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 8:35:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/24/2026 11:40:00 AM. 50 Economy ticket for $212 per person are available. Travel duration is 15h 5m
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LOT Polish Airlines / Polskie Linie Lotnicze18h 55m07:40 PMPrague AirportPrague Airport - T1/22:35 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 7:40:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/24/2026 2:35:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 18h 55m
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Bulgaria Air26h 30m09:10 AMPrague AirportPrague Airport - T1/211:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Bulgaria Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 9:10:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 10/24/2026 11:40:00 AM. 50 Economy ticket for $189 per person are available. Travel duration is 26h 30m
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FlixBus36h 45m010:45 PMPrague AirportPrague Airport - T1/210:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 10:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/25/2026 10:30:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 36h 45m
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FlixBus37h 50m06:50 PMPrague AirportPrague Airport - T1/27:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/25/2026 7:40:00 AM. 50 Economy ticket for $164 per person are available. Travel duration is 37h 50m
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FlixBus48h 55m07:00 AMPrague AirportPrague Airport - T1/26:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/23/2026 7:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/25/2026 6:55:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 48h 55m
Fastest Flights Friday
Fastest Buses Friday
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FlixBus37h 45m010:45 PMPrague AirportPrague Airport - T1/211:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/24/2026 10:45:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/26/2026 11:30:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 37h 45m
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FlixBus38h 50m06:50 PMPrague AirportPrague Airport - T1/28:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/24/2026 6:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 10/26/2026 8:40:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 38h 50m
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FlixBus49h 55m07:00 AMPrague AirportPrague Airport - T1/27:55 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/24/2026 7:00:00 AM to Sur Bus Station, Madrid (Spain) arriving at 10/26/2026 7:55:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 49h 55m
Fastest Buses Saturday
Here you will find all operators and timetables for a
Bus from Prague to Madrid
What are the most popular stations in Prague and Madrid?
In Prague, you will usually depart from Wilsonova Bus Station, ÚAN Florenc or Roztyly, while in Madrid you will be arriving at Sur Bus Station, Benavente Bus Station or Chamartin Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Madrid from Prague? With 6 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Madrid, you can pay as low as $62 with a Flight from Wizz Air.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Air Europa: you will get to Madrid in just 3h 10m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Madrid are FlixBus, Wizz Air and Bulgaria Air, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Madrid is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Delicias, and look at flights from Prague Airport, and landing at Adolfo Suárez Madrid-Barajas Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Madrid?
The most popular companies between Prague and Madrid, are FlixBus, Wizz Air and Bulgaria Air. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: Wizz Air, Bulgaria Air, EasyJet Airline and 9 more.
All you need to know when you travel from Prague to Madrid
Check all information on comfort and services on all modes of transports from Prague to Madrid. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Madrid
How can I reach Madrid from Prague?
Every day, there are on average 6 connections between Flight and Bus, with which you can get to Madrid from Prague.
How far is Madrid from Prague?
The distance between Prague and Madrid is 1,101.9 miles.
What is the most ecofriendly mode of transport between Prague and Madrid?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 48 kgs of CO2, a train 62 kgs, a car 301 kgs, and a flight 436 kgs.
What is the cheapest mode of transport from Prague to Madrid?
You can get to Madrid with just $62 by taking a Flight from Wizz Air.
What is the fastest way to get from Prague to Madrid?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Madrid in just 3h 10m with a Flight from Air Europa.
More routes to Prague and to Madrid
Looking for more options? Here you can see the most popular routes to Prague and to Madrid. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Bologna to Prague
- Bratislava to Prague
- Brno to Prague
- Budapest to Prague
- Cheb to Prague
- Dresden to Prague
- Dusseldorf to Prague
- Frankfurt am Main to Prague
- Hamburg to Prague
- Hanover to Prague
- Hradec Kralove to Prague
- Karlovy Vary to Prague
- Krakow to Prague
- London to Prague
- Manchester to Prague
- Munich to Prague
- Nuremberg to Prague
- Prague Airport to Prague
- Salzburg to Prague
- Třebíč to Prague
- Vienna to Prague
- Zurich to Prague
- Trips to Madrid
- A Coruña to Madrid
- Alicante to Madrid
- Almería to Madrid
- Barcelona to Madrid
- Benidorm to Madrid
- Bilbao to Madrid
- Cuenca to Madrid
- Granada to Madrid
- Linares to Madrid
- Lisbon to Madrid
- Lleida to Madrid
- Malaga to Madrid
- Martín Muñoz de las Posadas to Madrid
- Ourense to Madrid
- Oviedo to Madrid
- Pamplona to Madrid
- Pontevedra to Madrid
- Reinosa to Madrid
- San Sebastian to Madrid
- Santander to Madrid
- Santiago de Compostela to Madrid
- Talavera de la Reina to Madrid
- Vienna to Madrid
- Zaragoza to Madrid
