Bus Appleton, WI to Indianapolis - Compare all Companies

Compare all timetables for the bus from Appleton, WI to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from Appleton, WI to Indianapolis from various bus operators like FlixBus for the next days.

today

tomorrow

$57

Wednesday

Thursday

Friday

Saturday

$60

Sunday

$60

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	8h 20m	9:30 AM	Appleton, WI	Bus Stop	6:50 PM	Indianapolis	Central Bus Station		Economy	$57	A Bus from FlixBus goes from Bus Stop, Appleton, WI (USA) at 4/21/2026 9:30:00 AM to Central Bus Station, Indianapolis (USA) arriving at 4/21/2026 6:50:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 8h 20m
	FlixBus	12h 50m	9:30 AM	Appleton, WI	Bus Stop	11:20 PM	Indianapolis	Downtown Transit Center		Economy	$57	A Bus from FlixBus goes from Bus Stop, Appleton, WI (USA) at 4/21/2026 9:30:00 AM to Downtown Transit Center, Indianapolis (USA) arriving at 4/21/2026 11:20:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 12h 50m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	12h 50m	9:30 AM	Appleton, WI	Bus Stop	11:20 PM	Indianapolis	Washington / Delaware		Economy	$60	A Bus from FlixBus goes from Bus Stop, Appleton, WI (USA) at 4/25/2026 9:30:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 4/25/2026 11:20:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 12h 50m
	FlixBus	8h 20m	9:30 AM	Appleton, WI	Bus Stop	6:50 PM	Indianapolis	Central Bus Station		Economy	$61	A Bus from FlixBus goes from Bus Stop, Appleton, WI (USA) at 4/25/2026 9:30:00 AM to Central Bus Station, Indianapolis (USA) arriving at 4/25/2026 6:50:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 8h 20m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	8h 20m	9:30 AM	Appleton, WI	Bus Stop	6:50 PM	Indianapolis	Central Bus Station		Economy	$60	A Bus from FlixBus goes from Bus Stop, Appleton, WI (USA) at 4/26/2026 9:30:00 AM to Central Bus Station, Indianapolis (USA) arriving at 4/26/2026 6:50:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 8h 20m
	FlixBus	12h 50m	9:30 AM	Appleton, WI	Bus Stop	11:20 PM	Indianapolis	Downtown Transit Center		Economy	$61	A Bus from FlixBus goes from Bus Stop, Appleton, WI (USA) at 4/26/2026 9:30:00 AM to Downtown Transit Center, Indianapolis (USA) arriving at 4/26/2026 11:20:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 12h 50m

Best Price Offer: The price for the cheapest bus from Appleton, WI to Indianapolis is $49 on 5/4/2026. Flexible travelers save on ticket prices.

Facts about the bus from Appleton, WI to Indianapolis

Compare all providers like FlixBus that travel 2 times every day by bus from Appleton, WI to Indianapolis in one click! Book your bus ticket from Appleton, WI to Indianapolis starting from $49!

Cheapest Bus	$49
Fastest Bus	9h 20m
Earliest Bus	9:30 AM
Latest Bus	9:30 AM
Daily Bus Routes	2 Ø
Distance	331.6 miles
Bus Companies	FlixBus

Cheapest bus connections from Appleton, WI to Indianapolis

Every day, 2 buses from 1 bus companies leave Appleton, WI for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

Tuesday 04/21

$57

Wednesday 04/22

Thursday 04/23

Friday 04/24

Saturday 04/25

$60

Sunday 04/26

$60

Monday 04/27

Tuesday 04/28

$57

Wednesday 04/29

Thursday 04/30

Friday 05/01

$60

Saturday 05/02

$59

Sunday 05/03

$58

Monday 05/04

$49

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$58

Saturday 05/09

$62

Sunday 05/10

Monday 05/11

$55

Tuesday 05/12

Wednesday 05/13

Thursday 05/14

Friday 05/15

$66

Saturday 05/16

How to save money travelling from Appleton, WI to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Appleton, WI to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Appleton, WI to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Appleton, WI to Indianapolis are also emptier.

All bus stations and stops in Appleton, WI and Indianapolis

In the map below, you can see where to find all bus stations in Appleton, WI and Indianapolis.

Bus Stop

E Washington St 100

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Central Bus Station

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

Service and Comfort on the bus from Appleton, WI to Indianapolis

Want to know which seat classes are available on the buses from Appleton, WI to Indianapolis? Or which bus companies serve the route Appleton, WI to Indianapolis? Below you will find answers to your questions.

FAQs about the Appleton, WI to Indianapolis bus

How much does a Appleton, WI Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $49 and takes 9h 20m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from Appleton, WI to Indianapolis?

This route is offered by 1 companies with a range of ticket prices between $49 and $61. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from Appleton, WI to Indianapolis each day?

Every day, the Appleton, WI to Indianapolis bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Appleton, WI to Indianapolis take?

The fastest bus from Appleton, WI to Indianapolis is offered by FlixBus and takes 9h 20m. Bus tickets for this connection cost $57. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Appleton, WI to Indianapolis?

The earliest bus arriving in Indianapolis from Appleton, WI starts at 9:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Appleton, WI to Indianapolis?

The latest bus trip departing from Appleton, WI for Indianapolis starts at 9:30 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Appleton, WI Indianapolis route?

When traveling by bus from Appleton, WI to Indianapolis, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Appleton, WI and Indianapolis?

You can check all the direct connections between Appleton, WI and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Appleton, WI to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Appleton, WI Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Appleton, WI Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Appleton, WI to Indianapolis on your planned travel date.

How does CheckMyBus find the best bus deals from Appleton, WI to Indianapolis?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Appleton, WI and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Appleton, WI to Indianapolis?

Prices and availability for 2 trips between Appleton, WI and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Appleton, WI to Indianapolis

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Appleton, WI and to Indianapolis

Here’s an overview of the most popular bus routes to Appleton, WI and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!