Bus Brindisi to Milan - Compare all Companies

Compare all timetables for the bus from Brindisi to Milan

Here is a selection of the cheapest bus trips from the schedule from Brindisi to Milan from various bus operators like Itabus, MarinoBus or FlixBus for the next days.

today

$47

tomorrow

$38

Wednesday

$34

Thursday

$26

Friday

$26

Saturday

$26

Sunday

$26

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	19h 45m	12:05 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	7:50 AM	Milan	Lampugnano Bus Station	Premium Economy	$47	A Bus from Itabus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/13/2026 12:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/14/2026 7:50:00 AM. 50 Premium Economy ticket for $47 per person are available. Travel duration is 19h 45m
Itabus	18h 50m	12:05 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	6:55 AM	Milan	Lampugnano Bus Station	Premium Economy	$50	A Bus from Itabus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/13/2026 12:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/14/2026 6:55:00 AM. 50 Premium Economy ticket for $50 per person are available. Travel duration is 18h 50m
FlixBus	17h 40m	11:30 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	5:10 PM	Milan	Lampugnano Bus Station	Economy	$75	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/13/2026 11:30:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/14/2026 5:10:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 17h 40m
FlixBus	19h 0m	11:30 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	6:30 PM	Milan	San Donato Bus Station	Economy	$77	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/13/2026 11:30:00 PM to San Donato Bus Station, Milan (Italy) arriving at 4/14/2026 6:30:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 19h 0m
MarinoBus	12h 50m	8:50 PM	Brindisi	Tribunale Bus Stop	9:40 AM	Milan	San Donato Bus Station	Basic	$103	A Bus from MarinoBus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/13/2026 8:50:00 PM to San Donato Bus Station, Milan (Italy) arriving at 4/14/2026 9:40:00 AM. 50 Basic ticket for $103 per person are available. Travel duration is 12h 50m

Did you know that if you travel from Brindisi to Milan via Bologna, you can save more than $12? You can find the corresponding connections below.
- Itabus
  
  18h 5m
  
  0
  
  5:30 AM
  
  Brindisi
  Via Giuseppe Maria Galanti Bus Stop
  
  7:20 PM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Premium Economy
  
  $29
  
  A Bus from Itabus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/15/2026 5:30:00 AM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 4/15/2026 7:20:00 PM. 50 Premium Economy ticket for $29 per person are available. Travel duration is 13h 50m
- FlixBus
  
  3h 15m
  
  0
  
  8:20 PM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  11:35 PM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Economy
  
  $6
  
  A Bus from FlixBus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 4/15/2026 8:20:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/15/2026 11:35:00 PM. 50 Economy ticket for $6 per person are available. Travel duration is 3h 15m
Travel time is 5h 15m longer, but you will save $12

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	19h 0m	12:05 PM	Brindisi	Tribunale Bus Stop	7:05 AM	Milan	San Donato Bus Station	Premium Economy	$38	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/14/2026 12:05:00 PM to San Donato Bus Station, Milan (Italy) arriving at 4/15/2026 7:05:00 AM. 50 Premium Economy ticket for $38 per person are available. Travel duration is 19h 0m
Itabus	18h 20m	10:50 PM	Brindisi	Tribunale Bus Stop	5:10 PM	Milan	Lampugnano Bus Station	Premium Economy	$39	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/14/2026 10:50:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/15/2026 5:10:00 PM. 50 Premium Economy ticket for $39 per person are available. Travel duration is 18h 20m
FlixBus	14h 0m	6:15 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	8:15 AM	Milan	Lampugnano Bus Station	Economy	$42	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/14/2026 6:15:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/15/2026 8:15:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 14h 0m
FlixBus	13h 15m	6:15 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	7:30 AM	Milan	San Donato Bus Station	Economy	$42	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/14/2026 6:15:00 PM to San Donato Bus Station, Milan (Italy) arriving at 4/15/2026 7:30:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 13h 15m
MarinoBus	13h 15m	5:45 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	7:00 AM	Milan	Lampugnano Bus Station	Economy	$49	A Bus from MarinoBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/14/2026 5:45:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/15/2026 7:00:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 13h 15m

Did you know that if you travel from Brindisi to Milan via Bologna, you can save more than $6? You can find the corresponding connections below.
- Itabus
  
  14h 50m
  
  0
  
  4:05 PM
  
  Brindisi
  Tribunale Bus Stop
  
  2:50 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Premium Economy
  
  $25
  
  A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/16/2026 4:05:00 PM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 4/17/2026 2:50:00 AM. 50 Premium Economy ticket for $25 per person are available. Travel duration is 10h 45m
- FlixBus
  
  2h 50m
  
  0
  
  4:05 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  6:55 AM
  
  Milan
  Lampugnano Bus Station
  
  0
  
  Economy
  
  $7
  
  A Bus from FlixBus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 4/17/2026 4:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 4/17/2026 6:55:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 50m
Travel time is 1h 35m longer, but you will save $6

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	19h 0m	12:05 PM	Brindisi	Tribunale Bus Stop	7:05 AM	Milan	San Donato Bus Station	Premium Economy	$34	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/15/2026 12:05:00 PM to San Donato Bus Station, Milan (Italy) arriving at 4/16/2026 7:05:00 AM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 19h 0m
MarinoBus	13h 15m	5:45 PM	Brindisi	Tribunale Bus Stop	7:00 AM	Milan	Lampugnano Bus Station	Basic	$38	A Bus from MarinoBus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/15/2026 5:45:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/16/2026 7:00:00 AM. 50 Basic ticket for $38 per person are available. Travel duration is 13h 15m
MarinoBus	13h 30m	8:50 PM	Brindisi	Tribunale Bus Stop	10:20 AM	Milan	Lampugnano Bus Station	Basic	$38	A Bus from MarinoBus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/15/2026 8:50:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/16/2026 10:20:00 AM. 50 Basic ticket for $38 per person are available. Travel duration is 13h 30m
Itabus	17h 50m	10:50 PM	Brindisi	Tribunale Bus Stop	4:40 PM	Milan	Lampugnano Bus Station	Premium Economy	$39	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/15/2026 10:50:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/16/2026 4:40:00 PM. 50 Premium Economy ticket for $39 per person are available. Travel duration is 17h 50m
FlixBus	14h 40m	6:05 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	8:45 PM	Milan	Lampugnano Bus Station	Economy	$53	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/15/2026 6:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 4/15/2026 8:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 14h 40m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	14h 5m	4:05 PM	Brindisi	Tribunale Bus Stop	6:10 AM	Milan	Lampugnano Bus Station	Premium Economy	$26	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/16/2026 4:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/17/2026 6:10:00 AM. 50 Premium Economy ticket for $26 per person are available. Travel duration is 14h 5m
Itabus	17h 50m	10:50 PM	Brindisi	Tribunale Bus Stop	4:40 PM	Milan	Lampugnano Bus Station	Premium Economy	$33	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/16/2026 10:50:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/17/2026 4:40:00 PM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 17h 50m
FlixBus	17h 30m	6:05 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	11:35 PM	Milan	Lampugnano Bus Station	Economy	$48	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/16/2026 6:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 4/16/2026 11:35:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 17h 30m
MarinoBus	13h 15m	5:45 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	7:00 AM	Milan	Lampugnano Bus Station	Economy	$49	A Bus from MarinoBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/16/2026 5:45:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/17/2026 7:00:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 13h 15m
FlixBus	13h 50m	6:05 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	7:55 PM	Milan	San Donato Bus Station	Economy	$50	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/16/2026 6:05:00 AM to San Donato Bus Station, Milan (Italy) arriving at 4/16/2026 7:55:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 13h 50m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	14h 5m	4:05 PM	Brindisi	Tribunale Bus Stop	6:10 AM	Milan	Lampugnano Bus Station	Premium Economy	$26	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/17/2026 4:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/18/2026 6:10:00 AM. 50 Premium Economy ticket for $26 per person are available. Travel duration is 14h 5m
Itabus	20h 45m	12:05 PM	Brindisi	Tribunale Bus Stop	8:50 AM	Milan	Lampugnano Bus Station	Premium Economy	$32	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/17/2026 12:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/18/2026 8:50:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 20h 45m
FlixBus	13h 35m	5:55 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	7:30 AM	Milan	San Donato Bus Station	Economy	$35	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/17/2026 5:55:00 PM to San Donato Bus Station, Milan (Italy) arriving at 4/18/2026 7:30:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 13h 35m
FlixBus	14h 20m	5:55 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	8:15 AM	Milan	Lampugnano Bus Station	Economy	$35	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/17/2026 5:55:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/18/2026 8:15:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 14h 20m
MarinoBus	13h 15m	5:45 PM	Brindisi	Tribunale Bus Stop	7:00 AM	Milan	Lampugnano Bus Station	Basic	$38	A Bus from MarinoBus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/17/2026 5:45:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/18/2026 7:00:00 AM. 50 Basic ticket for $38 per person are available. Travel duration is 13h 15m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	14h 5m	4:05 PM	Brindisi	Tribunale Bus Stop	6:10 AM	Milan	Lampugnano Bus Station	Premium Economy	$26	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/18/2026 4:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/19/2026 6:10:00 AM. 50 Premium Economy ticket for $26 per person are available. Travel duration is 14h 5m
Itabus	18h 20m	10:50 PM	Brindisi	Tribunale Bus Stop	5:10 PM	Milan	Lampugnano Bus Station	Premium Economy	$33	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/18/2026 10:50:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/19/2026 5:10:00 PM. 50 Premium Economy ticket for $33 per person are available. Travel duration is 18h 20m
FlixBus	18h 40m	12:40 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	7:20 AM	Milan	San Donato Bus Station	Economy	$35	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/18/2026 12:40:00 PM to San Donato Bus Station, Milan (Italy) arriving at 4/19/2026 7:20:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 18h 40m
FlixBus	17h 25m	12:40 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	6:05 AM	Milan	Lampugnano Bus Station	Economy	$37	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/18/2026 12:40:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/19/2026 6:05:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 17h 25m
MarinoBus	12h 40m	5:45 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	6:25 AM	Milan	San Donato Bus Station	Basic	$38	A Bus from MarinoBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/18/2026 5:45:00 PM to San Donato Bus Station, Milan (Italy) arriving at 4/19/2026 6:25:00 AM. 50 Basic ticket for $38 per person are available. Travel duration is 12h 40m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	14h 5m	4:05 PM	Brindisi	Tribunale Bus Stop	6:10 AM	Milan	Lampugnano Bus Station	Premium Economy	$26	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/19/2026 4:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 4/20/2026 6:10:00 AM. 50 Premium Economy ticket for $26 per person are available. Travel duration is 14h 5m
Itabus	18h 19m	5:30 AM	Brindisi	Tribunale Bus Stop	11:49 PM	Milan	San Donato Bus Station	Premium Economy	$36	A Bus from Itabus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/19/2026 5:30:00 AM to San Donato Bus Station, Milan (Italy) arriving at 4/19/2026 11:49:00 PM. 50 Premium Economy ticket for $36 per person are available. Travel duration is 18h 19m
MarinoBus	13h 5m	5:35 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	6:40 PM	Milan	San Donato Bus Station	Basic	$48	A Bus from MarinoBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/19/2026 5:35:00 AM to San Donato Bus Station, Milan (Italy) arriving at 4/19/2026 6:40:00 PM. 50 Basic ticket for $48 per person are available. Travel duration is 13h 5m
MarinoBus	13h 50m	5:35 AM	Brindisi	Tribunale Bus Stop	7:25 PM	Milan	Lampugnano Bus Station	Basic	$48	A Bus from MarinoBus goes from Tribunale Bus Stop, Brindisi (Italy) at 4/19/2026 5:35:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 4/19/2026 7:25:00 PM. 50 Basic ticket for $48 per person are available. Travel duration is 13h 50m
FlixBus	13h 50m	6:05 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	7:55 PM	Milan	San Donato Bus Station	Economy	$53	A Bus from FlixBus goes from Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) at 4/19/2026 6:05:00 AM to San Donato Bus Station, Milan (Italy) arriving at 4/19/2026 7:55:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 13h 50m

Best Price Offer: The price for the cheapest bus from Brindisi to Milan is $23 on 4/23/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Brindisi and Milan

See here how frequent the connections between Brindisi and Milan are, during different times and days of the week.

Saturday is the busiest day, with more than 72 daily buses from Brindisi to Milan. Monday has instead the fewest connections, with only 44 daily coaches between Brindisi and Milan.

The busiest time of the day is the Afternoon, with 227 buses from Brindisi to Milan, while Morning sees the fewest connections between Brindisi and Milan, with 26 offers.

Facts about the bus from Brindisi to Milan

Compare all providers like Itabus, MarinoBus and FlixBus that travel 54 times every day by bus from Brindisi to Milan in one click! Book your bus ticket from Brindisi to Milan starting from $23!

Cheapest Bus	$23
Fastest Bus	12h 40m
Earliest Bus	5:35 AM
Latest Bus	11:30 PM
Daily Bus Routes	54 Ø
Distance	553.7 miles
Bus Companies	Itabus, MarinoBus and FlixBus

Cheapest bus connections from Brindisi to Milan

Every day, 54 buses from 3 bus companies leave Brindisi for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/13/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/12

Monday 04/13

$52

Tuesday 04/14

$33

Wednesday 04/15

$33

Thursday 04/16

$26

Friday 04/17

$26

Saturday 04/18

$26

Sunday 04/19

$36

Monday 04/20

$34

Tuesday 04/21

$34

Wednesday 04/22

$42

Thursday 04/23

$23

Friday 04/24

$34

Saturday 04/25

$34

Sunday 04/26

$23

Monday 04/27

$34

Tuesday 04/28

$23

Wednesday 04/29

$23

Thursday 04/30

$34

Friday 05/01

$38

Saturday 05/02

$38

Sunday 05/03

$48

Monday 05/04

$77

Tuesday 05/05

$38

Wednesday 05/06

$32

Thursday 05/07

$27

Friday 05/08

$27

Saturday 05/09

The cheapest time to travel from Brindisi to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Brindisi to Milan, for the next 30 days.

With a price starting from $23, Sunday is the cheapest day for a bus from Brindisi to Milan. Monday instead is the most expensive day with prices starting from $34.

Night is the cheapest day time for bus tickets from Brindisi to Milan, with $23. Morning is the most expensive time of the day with prices starting from $43.

How to save money travelling from Brindisi to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Brindisi to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Brindisi to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Brindisi to Milan are also emptier.

Beloved bus companies from Brindisi to Milan

These are the most booked bus companies between Brindisi to Milan from our users.

Itabus from Brindisi to Milan

Here you will find the key facts about the Itabus bus route Brindisi to Milan:

Cheapest Price	$26
Fastest Bus	14h 5m
Earliest Bus	12:05 PM
Last Bus	10:50 PM
Daily Connections	29 Ø
Found on	4/13/2026

All bus stations and stops in Brindisi and Milan

In the map below, you can see where to find all bus stations in Brindisi and Milan.

Via Giuseppe Maria Galanti Bus Stop

Via Giuseppe Maria Galanti 8

Port

Ospedale "A. Perrino" Bus Stop

Costa Morena Bus Stop

Viale Arno Bus Stop

Viale Arno

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Central Station - Piazza Luigi di Savoia

Piazza Duca D'Aosta 16

Duomo Bus Stop

Piazza del Duomo

Service and Comfort on the bus from Brindisi to Milan

Want to know which seat classes are available on the buses from Brindisi to Milan? Or which bus companies serve the route Brindisi to Milan? Below you will find answers to your questions.

FAQs about the Brindisi to Milan bus

How much does a Brindisi Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $23 and takes 14h 5m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Brindisi to Milan?

This route is offered by 3 companies with a range of ticket prices between $23 and $136. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Brindisi to Milan each day?

Every day, the Brindisi to Milan bus route is served by approximately 54 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Brindisi to Milan take?

The fastest bus from Brindisi to Milan is offered by MarinoBus and takes 12h 40m. Bus tickets for this connection cost $136. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Brindisi to Milan?

The earliest bus arriving in Milan from Brindisi starts at 5:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Brindisi to Milan?

The latest bus trip departing from Brindisi for Milan starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Brindisi Milan route?

When traveling by bus from Brindisi to Milan, passengers can travel with Itabus, MarinoBus and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Brindisi and Milan?

You can check all the direct connections between Brindisi and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus, MarinoBus and FlixBus.

What can I take with me on the Brindisi to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Brindisi Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Brindisi Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Brindisi to Milan on your planned travel date.

How does CheckMyBus find the best bus deals from Brindisi to Milan?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 54 daily trips between Brindisi and Milan. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Brindisi to Milan?

Prices and availability for 54 trips between Brindisi and Milan change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Brindisi to Milan

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Brindisi and to Milan

Here’s an overview of the most popular bus routes to Brindisi and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!