Which bus from Buenos Aires to Santa Cruz de la Sierra is the cheapest?

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Compare all timetables for the bus from Buenos Aires to Santa Cruz de la Sierra

Here is a selection of the cheapest bus trips from the schedule from Buenos Aires to Santa Cruz de la Sierra from various bus operators like Autobuses Quirquincho or La Preferida Bus for the next days.

today
$161
tomorrow
$161
Tuesday
$161
Wednesday
Thursday
$161
Friday
$307
Saturday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Autobuses Quirquincho 38h 55m 3:00 PM Buenos Aires Retiro Bus Station 4:55 AM Santa Cruz de la Sierra Terminal Bimodal  First Class $161
La Preferida Bus 38h 0m 4:30 PM Buenos Aires Avenida Corrientes 6:30 AM Santa Cruz de la Sierra Terminal Bimodal  First Class $299

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Autobuses Quirquincho 38h 55m 3:00 PM Buenos Aires Retiro Bus Station 4:55 AM Santa Cruz de la Sierra Terminal Bimodal  First Class $161

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Autobuses Quirquincho 38h 55m 3:00 PM Buenos Aires Retiro Bus Station 4:55 AM Santa Cruz de la Sierra Terminal Bimodal  First Class $161
Autobuses Quirquincho 36h 55m 5:00 PM Buenos Aires Liniers Bus Station 4:55 AM Santa Cruz de la Sierra Terminal Bimodal  First Class $175
Autobuses Quirquincho 37h 55m 3:00 PM Buenos Aires Retiro Bus Station 3:55 AM Santa Cruz de la Sierra Terminal Bimodal  Premium Economy $204
La Preferida Bus 38h 0m 4:30 PM Buenos Aires Avenida Corrientes 6:30 AM Santa Cruz de la Sierra Terminal Bimodal  First Class $299

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Autobuses Quirquincho 38h 55m 3:00 PM Buenos Aires Retiro Bus Station 4:55 AM Santa Cruz de la Sierra Terminal Bimodal  First Class $161
Autobuses Quirquincho 36h 55m 5:00 PM Buenos Aires Liniers Bus Station 4:55 AM Santa Cruz de la Sierra Terminal Bimodal  First Class $161
Autobuses Quirquincho 37h 55m 3:00 PM Buenos Aires Retiro Bus Station 3:55 AM Santa Cruz de la Sierra Terminal Bimodal  Premium Economy $189
La Preferida Bus 38h 0m 4:30 PM Buenos Aires Avenida Corrientes 6:30 AM Santa Cruz de la Sierra Terminal Bimodal  First Class $307

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
La Preferida Bus 38h 0m 4:30 PM Buenos Aires Avenida Corrientes 6:30 AM Santa Cruz de la Sierra Terminal Bimodal  First Class $307
  • Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Asunción, PY, you can save more than $149? You can find the corresponding connections below.
    • DeÔnibus
      46h 30m
      0
      6:30 PM
      Buenos Aires
      Retiro Bus Station
      1:15 PM
      Asunción, PY
      Bus Station Assunção
      0
      DeÔnibus
      Premium Economy
      $67
      • Waiting Time 6h 45m
    • Plataforma 10
      21h 0m
      0
      8:00 PM
      Asunción, PY
      Bus Station Assunção
      4:00 PM
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Plataforma 10
      Premium Economy
      $91
    Travel time is 8h 30m longer, but you will save $149

Best Price Offer: The price for the cheapest bus from Buenos Aires to Santa Cruz de la Sierra is $161 on 2/9/2026. Flexible travelers save on ticket prices.


Facts about the bus from Buenos Aires to Santa Cruz de la Sierra

Compare all providers like Autobuses Quirquincho and La Preferida Bus that travel 4 times every day by bus from Buenos Aires to Santa Cruz de la Sierra in one click! Book your bus ticket from Buenos Aires to Santa Cruz de la Sierra starting from $161!

Cheapest Bus $161
Fastest Bus 34h 55m
Earliest Bus 3:00 PM
Latest Bus 4:30 PM
Daily Bus Routes 4 Ø
Distance 1,199.3 miles
Bus Companies Autobuses Quirquincho and La Preferida Bus

Cheapest bus connections from Buenos Aires to Santa Cruz de la Sierra

Every day, 4 buses from 2 bus companies leave Buenos Aires for Santa Cruz de la Sierra: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/08/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/08
$182
Monday 02/09
$161
Tuesday 02/10
$161
Wednesday 02/11
Thursday 02/12
$161
Friday 02/13
$307
Saturday 02/14
Sunday 02/15
$299
Monday 02/16
Tuesday 02/17
$299
Wednesday 02/18
Thursday 02/19
$299
Friday 02/20
Saturday 02/21
$299
Sunday 02/22
$299
Monday 02/23
Tuesday 02/24
$299
Wednesday 02/25
Thursday 02/26
$299
Friday 02/27
Saturday 02/28
Sunday 03/01
Monday 03/02
Tuesday 03/03
Wednesday 03/04
$234
Thursday 03/05
Friday 03/06
$234
Saturday 03/07

How to save money travelling from Buenos Aires to Santa Cruz de la Sierra

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Buenos Aires to Santa Cruz de la Sierra in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Buenos Aires to Santa Cruz de la Sierra, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Buenos Aires to Santa Cruz de la Sierra are also emptier.

Beloved bus companies from Buenos Aires to Santa Cruz de la Sierra

These are the most booked bus companies between Buenos Aires to Santa Cruz de la Sierra from our users.

La Preferida Bus from Buenos Aires to Santa Cruz de la Sierra

La Preferida Bus

Here you will find the key facts about the La Preferida Bus bus route Buenos Aires to Santa Cruz de la Sierra:

Cheapest Price $299
Fastest Bus 38h 0m
Earliest Bus 4:30 PM
Last Bus 4:30 PM
Daily Connections 1 Ø
Found on 2/5/2026

All bus stations and stops in Buenos Aires and Santa Cruz de la Sierra

In the map below, you can see where to find all bus stations in Buenos Aires and Santa Cruz de la Sierra.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Buenos Aires to Santa Cruz de la Sierra? Compare all modes of transports from Buenos Aires to Santa Cruz de la Sierra.

Service and Comfort on the bus from Buenos Aires to Santa Cruz de la Sierra

Want to know which seat classes are available on the buses from Buenos Aires to Santa Cruz de la Sierra? Or which bus companies serve the route Buenos Aires to Santa Cruz de la Sierra? Below you will find answers to your questions.

FAQs about the Buenos Aires to Santa Cruz de la Sierra bus

How much does a Buenos Aires Santa Cruz de la Sierra bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $161 and takes 37h 55m to reach Santa Cruz de la Sierra. Compare offers to save money!

How much could I save by comparing buses from Buenos Aires to Santa Cruz de la Sierra?

This route is offered by 2 companies with a range of ticket prices between $161 and $329. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Cruz de la Sierra.

On average, how many connections are available from Buenos Aires to Santa Cruz de la Sierra each day?

Every day, the Buenos Aires to Santa Cruz de la Sierra bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Buenos Aires to Santa Cruz de la Sierra take?

The fastest bus from Buenos Aires to Santa Cruz de la Sierra is offered by Autobuses Quirquincho and takes 34h 55m. Bus tickets for this connection cost $229. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Buenos Aires to Santa Cruz de la Sierra?

The earliest bus arriving in Santa Cruz de la Sierra from Buenos Aires starts at 3:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Buenos Aires to Santa Cruz de la Sierra?

The latest bus trip departing from Buenos Aires for Santa Cruz de la Sierra starts at 4:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Buenos Aires Santa Cruz de la Sierra route?

When traveling by bus from Buenos Aires to Santa Cruz de la Sierra, passengers can travel with Autobuses Quirquincho and La Preferida Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Buenos Aires and Santa Cruz de la Sierra?

You can check all the direct connections between Buenos Aires and Santa Cruz de la Sierra by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Autobuses Quirquincho and La Preferida Bus.

What can I take with me on the Buenos Aires to Santa Cruz de la Sierra bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Buenos Aires Santa Cruz de la Sierra bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Buenos Aires Santa Cruz de la Sierra bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Buenos Aires to Santa Cruz de la Sierra on your planned travel date.

How does CheckMyBus find the best bus deals from Buenos Aires to Santa Cruz de la Sierra?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Buenos Aires and Santa Cruz de la Sierra. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Buenos Aires to Santa Cruz de la Sierra?

Prices and availability for 4 trips between Buenos Aires and Santa Cruz de la Sierra change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Buenos Aires to Santa Cruz de la Sierra

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Buenos Aires and to Santa Cruz de la Sierra

Here’s an overview of the most popular bus routes to Buenos Aires and to Santa Cruz de la Sierra. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses from Pergamino to Buenos Aires Buses from Pergamino to Buenos Aires
Buses Santo Tomé, SF - Buenos Aires Buses Santo Tomé, SF - Buenos Aires
Bus from Sierra de La Ventana to Buenos Aires Bus from Sierra de La Ventana to Buenos Aires
From Trelew to Buenos Aires bus From Trelew to Buenos Aires bus
Bus Iquique to Santa Cruz de la Sierra Bus Iquique to Santa Cruz de la Sierra
Villazón to Santa Cruz de la Sierra bus Villazón to Santa Cruz de la Sierra bus
Buses Tarija - Santa Cruz de la Sierra Buses Tarija - Santa Cruz de la Sierra
From Uyuni to Santa Cruz de la Sierra bus From Uyuni to Santa Cruz de la Sierra bus
Popular Airport Shuttles to Buenos Aires and to Santa Cruz de la Sierra
CheckMyBus › Buses in Argentina › Bus to Buenos Aires › Bus to Santa Cruz de la Sierra

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