Bus from Buenos Aires to Santa Cruz de la Sierra from $135

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Compare all timetables for the bus from Buenos Aires to Santa Cruz de la Sierra

Here is a selection of the cheapest bus trips from the schedule from Buenos Aires to Santa Cruz de la Sierra from various bus operators like Autobuses Quirquincho or La Preferida Bus for the next days.

today
tomorrow
from $182
Monday
from $182
Tuesday
from $135
Wednesday
from $182
Thursday
from $135
Friday

Cheapest bus trips tomorrow

Prices are for one way and one person
  • La Preferida Bus
    38h 0m
    0
    4:30 PM
    Buenos Aires
    Avenida Corrientes
    6:30 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    $182

Cheapest bus trips Monday

Prices are for one way and one person
  • La Preferida Bus
    38h 0m
    0
    4:30 PM
    Buenos Aires
    Avenida Corrientes
    6:30 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    $182
  • Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Tarija, you can save more than $27? You can find the corresponding connections below.
    • Central de Pasajes
      43h 0m
      0
      12:00 PM
      Buenos Aires
      Liniers Bus Station
      4:35 PM
      Tarija
      Julio Pantoja
      0
      Central de Pasajes
      Premium Economy
      $118
      • Waiting Time 2h 25m
    • Tickets Bolivia
      12h 0m
      0
      7:00 PM
      Tarija
      Nueva Terminal de Buses
      7:00 AM
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Tickets Bolivia
      First Class
      $37
    Travel time is 5h 0m longer, but you will save $27

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Autobuses Quirquincho
    35h 55m
    0
    5:00 PM
    Buenos Aires
    Liniers Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $135
  • Autobuses Quirquincho
    35h 55m
    0
    5:00 PM
    Buenos Aires
    Liniers Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $147
  • Autobuses Quirquincho
    37h 55m
    0
    3:00 PM
    Buenos Aires
    Retiro Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $156

Cheapest bus trips Wednesday

Prices are for one way and one person
  • La Preferida Bus
    38h 0m
    0
    4:30 PM
    Buenos Aires
    Avenida Corrientes
    6:30 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    $182
  • Did you know that if you travel from Buenos Aires to Santa Cruz de la Sierra via Tarija, you can save more than $27? You can find the corresponding connections below.
    • Central de Pasajes
      43h 0m
      0
      12:00 PM
      Buenos Aires
      Liniers Bus Station
      4:35 PM
      Tarija
      Julio Pantoja
      0
      Central de Pasajes
      Premium Economy
      $118
      • Waiting Time 2h 25m
    • Tickets Bolivia
      12h 0m
      0
      7:00 PM
      Tarija
      Nueva Terminal de Buses
      7:00 AM
      Santa Cruz de la Sierra
      Terminal Bimodal
      0
      Tickets Bolivia
      First Class
      $37
    Travel time is 5h 0m longer, but you will save $27

Cheapest bus trips Thursday

Prices are for one way and one person
  • Autobuses Quirquincho
    37h 55m
    0
    3:00 PM
    Buenos Aires
    Retiro Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $135
  • Autobuses Quirquincho
    35h 55m
    0
    5:00 PM
    Buenos Aires
    Liniers Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $135
  • Autobuses Quirquincho
    35h 55m
    0
    5:00 PM
    Buenos Aires
    Liniers Bus Station
    4:55 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    Autobuses Quirquincho
    First Class
    $147
  • La Preferida Bus
    38h 0m
    0
    4:30 PM
    Buenos Aires
    Avenida Corrientes
    6:30 AM
    Santa Cruz de la Sierra
    Terminal Bimodal
    0
    La Preferida Bus
    First Class
    $182

Facts about the bus from Buenos Aires to Santa Cruz de la Sierra

Compare all providers like Autobuses Quirquincho and La Preferida Bus that travel 2 times every day by bus from Buenos Aires to Santa Cruz de la Sierra in one click! Book your bus ticket from Buenos Aires to Santa Cruz de la Sierra starting from $135!

Cheapest Bus $135
Fastest Bus 35h 55m
Earliest Bus 4:30 PM
Latest Bus 5:00 PM
Daily Bus Routes 2 Ø
Distance 1,199.3 miles
Bus Companies Autobuses Quirquincho and La Preferida Bus

Cheapest bus connections from Buenos Aires to Santa Cruz de la Sierra

Every day, 2 buses from 2 bus companies leave Buenos Aires for Santa Cruz de la Sierra: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/28/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
Monday 06/23
Tuesday 06/24
Wednesday 06/25
Thursday 06/26
Friday 06/27
Saturday 06/28
Sunday 06/29
$182
Monday 06/30
$182
Tuesday 07/01
$135
Wednesday 07/02
$182
Thursday 07/03
$182
Friday 07/04
Saturday 07/05
$182
Sunday 07/06
$182
Monday 07/07
$182
Tuesday 07/08
$182
Wednesday 07/09
Thursday 07/10
Friday 07/11
$182
Saturday 07/12
$182
Sunday 07/13
Monday 07/14
Tuesday 07/15
$182
Wednesday 07/16
$182
Thursday 07/17
Friday 07/18
$182
Saturday 07/19

How to save money travelling from Buenos Aires to Santa Cruz de la Sierra

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Buenos Aires to Santa Cruz de la Sierra in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Buenos Aires to Santa Cruz de la Sierra, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Buenos Aires to Santa Cruz de la Sierra are also emptier.

Beloved bus companies from Buenos Aires to Santa Cruz de la Sierra

These are the most booked bus companies between Buenos Aires to Santa Cruz de la Sierra from our users.

La Preferida Bus from Buenos Aires to Santa Cruz de la Sierra

La Preferida Bus

Here you will find the key facts about the La Preferida Bus bus route Buenos Aires to Santa Cruz de la Sierra:

Cheapest Price $182
Fastest Bus 38h 0m
Earliest Bus 4:30 PM
Last Bus 4:30 PM
Daily Connections 1 Ø
Found on 6/25/2025

All bus stations and stops in Buenos Aires and Santa Cruz de la Sierra

In the map below, you can see where to find all bus stations in Buenos Aires and Santa Cruz de la Sierra.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Buenos Aires to Santa Cruz de la Sierra? Compare all modes of transports from Buenos Aires to Santa Cruz de la Sierra.

Service and Comfort on the bus from Buenos Aires to Santa Cruz de la Sierra

Want to know which seat classes are available on the buses from Buenos Aires to Santa Cruz de la Sierra? Or which bus companies serve the route Buenos Aires to Santa Cruz de la Sierra? Below you will find answers to your questions.

FAQs about the Buenos Aires to Santa Cruz de la Sierra bus

How much does a Buenos Aires Santa Cruz de la Sierra bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $135 and takes 35h 55m to reach Santa Cruz de la Sierra. Compare offers to save money!

How much could I save by comparing buses from Buenos Aires to Santa Cruz de la Sierra?

This route is offered by 2 companies with a range of ticket prices between $135 and $182. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Cruz de la Sierra.

On average, how many connections are available from Buenos Aires to Santa Cruz de la Sierra each day?

Every day, the Buenos Aires to Santa Cruz de la Sierra bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Buenos Aires to Santa Cruz de la Sierra take?

The fastest bus from Buenos Aires to Santa Cruz de la Sierra is offered by Autobuses Quirquincho and takes 35h 55m. Bus tickets for this connection cost $147. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Buenos Aires to Santa Cruz de la Sierra?

The earliest bus arriving in Santa Cruz de la Sierra from Buenos Aires starts at 4:30 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Buenos Aires to Santa Cruz de la Sierra?

The latest bus trip departing from Buenos Aires for Santa Cruz de la Sierra starts at 5:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Buenos Aires Santa Cruz de la Sierra route?

When traveling by bus from Buenos Aires to Santa Cruz de la Sierra, passengers can travel with Autobuses Quirquincho and La Preferida Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Buenos Aires and Santa Cruz de la Sierra?

You can check all the direct connections between Buenos Aires and Santa Cruz de la Sierra by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Autobuses Quirquincho and La Preferida Bus.

What can I take with me on the Buenos Aires to Santa Cruz de la Sierra bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Buenos Aires Santa Cruz de la Sierra bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Buenos Aires Santa Cruz de la Sierra bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Buenos Aires to Santa Cruz de la Sierra on your planned travel date.

Available seat classes which are offered on the bus route Buenos Aires to Santa Cruz de la Sierra

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Buenos Aires and to Santa Cruz de la Sierra

Here’s an overview of the most popular bus routes to Buenos Aires and to Santa Cruz de la Sierra. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Buses Asunción, PY - Santa Cruz de la Sierra Buses Asunción, PY - Santa Cruz de la Sierra
Sucre to Santa Cruz de la Sierra bus Sucre to Santa Cruz de la Sierra bus
Bus from La Paz to Santa Cruz de la Sierra Bus from La Paz to Santa Cruz de la Sierra
Bus from Cochabamba to Santa Cruz de la Sierra Bus from Cochabamba to Santa Cruz de la Sierra
Popular Airport Shuttles to Buenos Aires and to Santa Cruz de la Sierra
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