Bus from Chicago to Mississauga, ON from $45

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Compare all timetables for the bus from Chicago to Mississauga, ON

Here is a selection of the cheapest bus trips from the schedule from Chicago to Mississauga, ON from various bus operators like Greyhound US or FlixBus for the next days.

today
from $99
tomorrow
from $70
Tuesday
from $71
Wednesday
Thursday
from $65
Friday
from $53
Saturday
from $45

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    13h 20m
    0
    3:55 PM
    Chicago
    Downtown Bus Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $99
  • Greyhound US
    19h 15m
    0
    10:00 AM
    Chicago
    Canal & Van Buren
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $101
  • Greyhound US
    13h 20m
    0
    3:55 PM
    Chicago
    Downtown Bus Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $103
  • Greyhound US
    19h 15m
    0
    10:00 AM
    Chicago
    Union Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $105
  • Greyhound US
    15h 10m
    0
    2:05 PM
    Chicago
    95th Red Line Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $111
  • Did you know that if you travel from Chicago to Mississauga, ON via London, ON, you can save more than $32? You can find the corresponding connections below.
    • Busbud
      15h 10m
      0
      2:05 PM
      Chicago
      95th Red Line Station
      2:45 AM
      London, ON
      London (City Plaza - Downtown) Bus Stop
      0
      Busbud
      Economy
      $43
      • Waiting Time 0h 5m
    • Busbud
      2h 25m
      0
      2:50 AM
      London, ON
      London (City Plaza - Downtown) Bus Stop
      5:15 AM
      Mississauga, ON
      City Centre Dr / Duke of York Blvd
      0
      Busbud
      Economy
      $23
    Travel time is 1h 50m longer, but you will save $32

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    13h 20m
    0
    3:55 PM
    Chicago
    Downtown Bus Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $70
  • Greyhound US
    13h 20m
    0
    3:55 PM
    Chicago
    Downtown Bus Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $74
  • Greyhound US
    15h 10m
    0
    2:05 PM
    Chicago
    95th Red Line Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $86
  • Greyhound US
    15h 10m
    0
    2:05 PM
    Chicago
    95th Red Line Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $90
  • Greyhound US
    19h 15m
    0
    10:00 AM
    Chicago
    Canal & Van Buren
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $97
  • Did you know that if you travel from Chicago to Mississauga, ON via London, ON, you can save more than $8? You can find the corresponding connections below.
    • Busbud
      17h 10m
      0
      7:40 PM
      Chicago
      95th Red Line Station
      10:10 AM
      London, ON
      London (City Plaza - Downtown) Bus Stop
      0
      Busbud
      Economy
      $43
      • Waiting Time 0h 30m
    • Busbud
      2h 10m
      0
      10:40 AM
      London, ON
      The D.B. Weldon Library
      12:50 PM
      Mississauga, ON
      Mavis Rd At Cantay Rd Bus Stop
      0
      Busbud
      Economy
      $19
    Travel time is 3h 50m longer, but you will save $8

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    15h 10m
    0
    2:05 PM
    Chicago
    95th Red Line Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $71
  • Greyhound US
    15h 10m
    0
    2:05 PM
    Chicago
    95th Red Line Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $73
  • Greyhound US
    13h 20m
    0
    3:55 PM
    Chicago
    Downtown Bus Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $74
  • Greyhound US
    13h 20m
    0
    3:55 PM
    Chicago
    Downtown Bus Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $76
  • Greyhound US
    19h 15m
    0
    10:00 AM
    Chicago
    Canal & Van Buren
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $93
  • Did you know that if you travel from Chicago to Mississauga, ON via London, ON, you can save more than $9? You can find the corresponding connections below.
    • Busbud
      17h 10m
      0
      7:40 PM
      Chicago
      95th Red Line Station
      10:10 AM
      London, ON
      London (City Plaza - Downtown) Bus Stop
      0
      Busbud
      Economy
      $43
      • Waiting Time 0h 30m
    • Busbud
      2h 10m
      0
      10:40 AM
      London, ON
      The D.B. Weldon Library
      12:50 PM
      Mississauga, ON
      Mavis Rd At Cantay Rd Bus Stop
      0
      Busbud
      Economy
      $19
    Travel time is 3h 50m longer, but you will save $9

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    29h 25m
    0
    11:50 PM
    Chicago
    95th Red Line Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    FlixBus
    Economy
    $65
  • FlixBus
    29h 25m
    0
    11:50 PM
    Chicago
    95th Red Line Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    FlixBus
    Economy
    $69
  • Did you know that if you travel from Chicago to Mississauga, ON via London, ON, you can save more than $11? You can find the corresponding connections below.
    • Busbud
      23h 33m
      0
      7:40 PM
      Chicago
      95th Red Line Station
      10:10 AM
      London, ON
      London (City Plaza - Downtown) Bus Stop
      0
      Busbud
      Economy
      $43
      • Waiting Time 7h 5m
    • ONEXBUS
      1h 58m
      0
      5:15 PM
      London, ON
      Elgin Hall
      7:13 PM
      Mississauga, ON
      Mavis Rd At Cantay Rd Bus Stop
      0
      ONEXBUS
      Economy
      $11
    Travel Time is 5h 52m shorter, and you will save $11

Cheapest bus trips Friday

Prices are for one way and one person
  • Greyhound US
    13h 20m
    0
    3:55 PM
    Chicago
    Downtown Bus Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $53
  • Greyhound US
    19h 15m
    0
    10:00 AM
    Chicago
    Canal & Van Buren
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $65
  • Greyhound US
    13h 20m
    0
    3:55 PM
    Chicago
    Downtown Bus Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $66
  • Greyhound US
    19h 15m
    0
    10:00 AM
    Chicago
    Union Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $70
  • Greyhound US
    15h 10m
    0
    2:05 PM
    Chicago
    95th Red Line Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $86

Cheapest bus trips Saturday

Prices are for one way and one person
  • Greyhound US
    13h 20m
    0
    3:55 PM
    Chicago
    Downtown Bus Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $45
  • Greyhound US
    19h 15m
    0
    10:00 AM
    Chicago
    Canal & Van Buren
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $61
  • Greyhound US
    13h 20m
    0
    3:55 PM
    Chicago
    Downtown Bus Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $63
  • Greyhound US
    19h 15m
    0
    10:00 AM
    Chicago
    Union Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $69
  • Greyhound US
    15h 10m
    0
    2:05 PM
    Chicago
    95th Red Line Station
    5:15 AM
    Mississauga, ON
    City Centre Dr / Duke of York Blvd
    0
    Greyhound US
    Economy
    $79

Frequency of bus connections between Chicago and Mississauga, ON

See here how frequent the connections between Chicago and Mississauga, ON are, during different times and days of the week.
Sunday is the busiest day, with more than 6 daily buses from Chicago to Mississauga, ON. Thursday has instead the fewest connections, with only 2 daily coaches between Chicago and Mississauga, ON.
The busiest time of the day is the Afternoon, with 20 buses from Chicago to Mississauga, ON, while Evening sees the fewest connections between Chicago and Mississauga, ON, with 2 offers.

Facts about the bus from Chicago to Mississauga, ON

Compare all providers like Greyhound US and FlixBus that travel 5 times every day by bus from Chicago to Mississauga, ON in one click! Book your bus ticket from Chicago to Mississauga, ON starting from $45!

Cheapest Bus $45
Fastest Bus 13h 20m
Earliest Bus 10:00 AM
Latest Bus 3:55 PM
Daily Bus Routes 5 Ø
Distance 422.6 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Chicago to Mississauga, ON

Every day, 5 buses from 2 bus companies leave Chicago for Mississauga, ON: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/29/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/29
$99
Monday 06/30
$70
Tuesday 07/01
$71
Wednesday 07/02
Thursday 07/03
$65
Friday 07/04
$53
Saturday 07/05
$45
Sunday 07/06
$137
Monday 07/07
$52
Tuesday 07/08
$45
Wednesday 07/09
Thursday 07/10
$84
Friday 07/11
$56
Saturday 07/12
$51
Sunday 07/13
$51
Monday 07/14
$41
Tuesday 07/15
$45
Wednesday 07/16
Thursday 07/17
$93
Friday 07/18
$58
Saturday 07/19
$53
Sunday 07/20
$55
Monday 07/21
$48
Tuesday 07/22
$52
Wednesday 07/23
Thursday 07/24
$75
Friday 07/25
$55
Saturday 07/26

The cheapest time to travel from Chicago to Mississauga, ON

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to Mississauga, ON, for the next 30 days.
With a price starting from $45, Saturday is the cheapest day for a bus from Chicago to Mississauga, ON. Sunday instead is the most expensive day with prices starting from $99.
Afternoon is the cheapest day time for bus tickets from Chicago to Mississauga, ON, with $45. Evening is the most expensive time of the day with prices starting from $65.

How to save money travelling from Chicago to Mississauga, ON

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to Mississauga, ON in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Mississauga, ON, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Mississauga, ON are also emptier.

Beloved bus companies from Chicago to Mississauga, ON

These are the most booked bus companies between Chicago to Mississauga, ON from our users.

Greyhound US from Chicago to Mississauga, ON

Greyhound US

Here you will find the key facts about the Greyhound US bus route Chicago to Mississauga, ON:

Cheapest Price $45
Fastest Bus 13h 20m
Earliest Bus 10:00 AM
Last Bus 3:55 PM
Daily Connections 6 Ø
Found on 6/27/2025

All bus stations and stops in Chicago and Mississauga, ON

In the map below, you can see where to find all bus stations in Chicago and Mississauga, ON.

Service and Comfort on the bus from Chicago to Mississauga, ON

Want to know which seat classes are available on the buses from Chicago to Mississauga, ON? Or which bus companies serve the route Chicago to Mississauga, ON? Below you will find answers to your questions.

FAQs about the Chicago to Mississauga, ON bus

How much does a Chicago Mississauga, ON bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $45 and takes 13h 20m to reach Mississauga, ON. Compare offers to save money!

How much could I save by comparing buses from Chicago to Mississauga, ON?

This route is offered by 2 companies with a range of ticket prices between $45 and $115. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mississauga, ON.

On average, how many connections are available from Chicago to Mississauga, ON each day?

Every day, the Chicago to Mississauga, ON bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to Mississauga, ON take?

The fastest bus from Chicago to Mississauga, ON is offered by Greyhound US and takes 13h 20m. Bus tickets for this connection cost $103. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to Mississauga, ON?

The earliest bus arriving in Mississauga, ON from Chicago starts at 10:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to Mississauga, ON?

The latest bus trip departing from Chicago for Mississauga, ON starts at 3:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago Mississauga, ON route?

When traveling by bus from Chicago to Mississauga, ON, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and Mississauga, ON?

You can check all the direct connections between Chicago and Mississauga, ON by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to Mississauga, ON bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Mississauga, ON bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago Mississauga, ON bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Mississauga, ON on your planned travel date.

Available seat classes which are offered on the bus route Chicago to Mississauga, ON

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to Mississauga, ON

Here’s an overview of the most popular bus routes to Chicago and to Mississauga, ON. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Chicago and to Mississauga, ON
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