Bus Chicago to Mississauga, ON - Compare all Companies

Compare all timetables for the bus from Chicago to Mississauga, ON

Here is a selection of the cheapest bus trips from the schedule from Chicago to Mississauga, ON from various bus operators like Greyhound US or FlixBus for the next days.

today

$85

tomorrow

$45

Saturday

$43

Sunday

$44

Monday

$43

Tuesday

$37

Wednesday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	28h 25m	11:50 PM	Chicago	95th Red Line Station	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd		Economy	$85	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 12/4/2025 11:50:00 PM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/6/2025 5:15:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 28h 25m

Did you know that if you travel from Chicago to Mississauga, ON via Pearson Toronto Airport, you can save more than $33? You can find the corresponding connections below.
- Busbud
  
  14h 50m
  
  0
  
  3:55 PM
  
  Chicago
  Downtown Bus Station
  
  5:40 AM
  
  Pearson Toronto Airport
  Pearson Toronto Airport
  
  0
  
  Economy
  
  $45
  
  A Bus from Busbud goes from Downtown Bus Station, Chicago (USA) at 12/5/2025 3:55:00 PM to Pearson Toronto Airport, Pearson Toronto Airport (Canada) arriving at 12/6/2025 5:40:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 12h 45m
- ONEXBUS
  
  0h 15m
  
  0
  
  7:30 AM
  
  Pearson Toronto Airport
  Pearson Toronto Airport
  
  7:45 AM
  
  Mississauga, ON
  Mavis Rd At Cantay Rd Bus Stop
  
  0
  
  Economy
  
  $7
  
  A Bus from ONEXBUS goes from Pearson Toronto Airport, Pearson Toronto Airport (Canada) at 12/6/2025 7:30:00 AM to Mavis Rd At Cantay Rd Bus Stop, Mississauga, ON (Canada) arriving at 12/6/2025 7:45:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 0h 15m
Travel Time is 14h 35m shorter, and you will save $33

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 20m	3:55 PM	Chicago	Downtown Bus Station	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$45	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/5/2025 3:55:00 PM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/6/2025 5:15:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 12h 20m
Greyhound US	18h 15m	10:00 AM	Chicago	Canal & Van Buren	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$58	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 12/5/2025 10:00:00 AM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/6/2025 5:15:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 18h 15m
Greyhound US	14h 30m	1:45 PM	Chicago	95th Red Line Station	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$81	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 12/5/2025 1:45:00 PM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/6/2025 5:15:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 30m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 20m	3:55 PM	Chicago	Downtown Bus Station	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$43	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/6/2025 3:55:00 PM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/7/2025 5:15:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 12h 20m
Greyhound US	18h 15m	10:00 AM	Chicago	Canal & Van Buren	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$57	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 12/6/2025 10:00:00 AM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/7/2025 5:15:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 18h 15m
Greyhound US	14h 30m	1:45 PM	Chicago	95th Red Line Station	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$62	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 12/6/2025 1:45:00 PM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/7/2025 5:15:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 14h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 20m	3:55 PM	Chicago	Downtown Bus Station	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$44	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/7/2025 3:55:00 PM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/8/2025 5:15:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 12h 20m
Greyhound US	18h 15m	10:00 AM	Chicago	Canal & Van Buren	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$57	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 12/7/2025 10:00:00 AM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/8/2025 5:15:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 18h 15m
Greyhound US	14h 30m	1:45 PM	Chicago	95th Red Line Station	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$82	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 12/7/2025 1:45:00 PM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/8/2025 5:15:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 14h 30m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 20m	3:55 PM	Chicago	Downtown Bus Station	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$43	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 3:55:00 PM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/9/2025 5:15:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 12h 20m
Greyhound US	18h 15m	10:00 AM	Chicago	Canal & Van Buren	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$58	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 12/8/2025 10:00:00 AM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/9/2025 5:15:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 18h 15m
Greyhound US	14h 30m	1:45 PM	Chicago	95th Red Line Station	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$76	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 12/8/2025 1:45:00 PM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/9/2025 5:15:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 14h 30m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 20m	3:55 PM	Chicago	Downtown Bus Station	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$37	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/9/2025 3:55:00 PM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/10/2025 5:15:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 12h 20m
Greyhound US	18h 15m	10:00 AM	Chicago	Canal & Van Buren	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$55	A Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 12/9/2025 10:00:00 AM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/10/2025 5:15:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 18h 15m
Greyhound US	14h 30m	1:45 PM	Chicago	95th Red Line Station	5:15 AM	Mississauga, ON	City Centre Dr / Duke of York Blvd	Economy	$57	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 12/9/2025 1:45:00 PM to City Centre Dr / Duke of York Blvd, Mississauga, ON (Canada) arriving at 12/10/2025 5:15:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 14h 30m

Best Price Offer: The price for the cheapest bus from Chicago to Mississauga, ON is $37 on 12/9/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and Mississauga, ON

See here how frequent the connections between Chicago and Mississauga, ON are, during different times and days of the week.

Sunday is the busiest day, with more than 6 daily buses from Chicago to Mississauga, ON. Thursday has instead the fewest connections, with only 2 daily coaches between Chicago and Mississauga, ON.

The busiest time of the day is the Afternoon, with 20 buses from Chicago to Mississauga, ON, while Evening sees the fewest connections between Chicago and Mississauga, ON, with 2 offers.

Facts about the bus from Chicago to Mississauga, ON

Compare all providers like Greyhound US and FlixBus that travel 5 times every day by bus from Chicago to Mississauga, ON in one click! Book your bus ticket from Chicago to Mississauga, ON starting from $37!

Cheapest Bus	$37
Fastest Bus	13h 20m
Earliest Bus	11:50 PM
Latest Bus	3:55 PM
Daily Bus Routes	5 Ø
Distance	422.6 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Chicago to Mississauga, ON

Every day, 5 buses from 2 bus companies leave Chicago for Mississauga, ON: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

$85

Friday 12/05

$45

Saturday 12/06

$43

Sunday 12/07

$44

Monday 12/08

$43

Tuesday 12/09

$37

Wednesday 12/10

Thursday 12/11

$114

Friday 12/12

$57

Saturday 12/13

$53

Sunday 12/14

$45

Monday 12/15

$54

Tuesday 12/16

$41

Wednesday 12/17

Thursday 12/18

Friday 12/19

$75

Saturday 12/20

Sunday 12/21

$94

Monday 12/22

$78

Tuesday 12/23

$114

Wednesday 12/24

Thursday 12/25

$93

Friday 12/26

$71

Saturday 12/27

The cheapest time to travel from Chicago to Mississauga, ON

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to Mississauga, ON, for the next 30 days.

With a price starting from $37, Tuesday is the cheapest day for a bus from Chicago to Mississauga, ON. Thursday instead is the most expensive day with prices starting from $85.

Afternoon is the cheapest day time for bus tickets from Chicago to Mississauga, ON, with $37. Evening is the most expensive time of the day with prices starting from $85.

How to save money travelling from Chicago to Mississauga, ON

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to Mississauga, ON in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Mississauga, ON, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Mississauga, ON are also emptier.

Beloved bus companies from Chicago to Mississauga, ON

These are the most booked bus companies between Chicago to Mississauga, ON from our users.

Greyhound US from Chicago to Mississauga, ON

Here you will find the key facts about the Greyhound US bus route Chicago to Mississauga, ON:

Cheapest Price	$37
Fastest Bus	13h 20m
Earliest Bus	10:00 AM
Last Bus	3:55 PM
Daily Connections	6 Ø
Found on	12/2/2025

All bus stations and stops in Chicago and Mississauga, ON

In the map below, you can see where to find all bus stations in Chicago and Mississauga, ON.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Mavis Rd At Cantay Rd Bus Stop

Mavis Rd At Cantay Rd Mavis Rd At Cantay Rd

Winston Churchill Bus Station

Mississauga (Winston Churchill) Mississauga (Winston Churchill)

Dundas St East

Dundas Street East 1050

Duke of York Blvd.

Applewood Village

N Service Rd 1077

Service and Comfort on the bus from Chicago to Mississauga, ON

Want to know which seat classes are available on the buses from Chicago to Mississauga, ON? Or which bus companies serve the route Chicago to Mississauga, ON? Below you will find answers to your questions.

FAQs about the Chicago to Mississauga, ON bus

How much does a Chicago Mississauga, ON bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $37 and takes 13h 20m to reach Mississauga, ON. Compare offers to save money!

How much could I save by comparing buses from Chicago to Mississauga, ON?

This route is offered by 2 companies with a range of ticket prices between $37 and $90. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mississauga, ON.

On average, how many connections are available from Chicago to Mississauga, ON each day?

Every day, the Chicago to Mississauga, ON bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to Mississauga, ON take?

The fastest bus from Chicago to Mississauga, ON is offered by Greyhound US and takes 13h 20m. Bus tickets for this connection cost $54. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to Mississauga, ON?

The earliest bus arriving in Mississauga, ON from Chicago starts at 11:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to Mississauga, ON?

The latest bus trip departing from Chicago for Mississauga, ON starts at 3:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago Mississauga, ON route?

When traveling by bus from Chicago to Mississauga, ON, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and Mississauga, ON?

You can check all the direct connections between Chicago and Mississauga, ON by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to Mississauga, ON bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Mississauga, ON bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago Mississauga, ON bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Mississauga, ON on your planned travel date.

Available seat classes which are offered on the bus route Chicago to Mississauga, ON

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to Mississauga, ON

Here’s an overview of the most popular bus routes to Chicago and to Mississauga, ON. Simply click on the connection of your choice, and you will find all the details about your bus route!