Which bus from Columbia, MO to Indianapolis is the cheapest?

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Compare all timetables for the bus from Columbia, MO to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from Columbia, MO to Indianapolis from various bus operators like Greyhound US for the next days.

today
$83
tomorrow
Wednesday
Thursday
Friday
Saturday
Sunday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 9h 50m 8:35 PM Columbia, MO Red Thread 7:25 AM Indianapolis Central Bus Station  Economy $83
Greyhound US 9h 50m 8:30 AM Columbia, MO Bus Stop 7:20 PM Indianapolis Central Bus Station  Economy $84
Greyhound US 10h 20m 8:05 PM Columbia, MO Bus Stop 7:25 AM Indianapolis Central Bus Station  Economy $84
Greyhound US 14h 45m 8:05 PM Columbia, MO Bus Stop 11:50 AM Indianapolis Downtown Transit Center  Economy $84
Greyhound US 14h 15m 8:35 PM Columbia, MO Red Thread 11:50 AM Indianapolis Downtown Transit Center  Economy $84
  • Did you know that if you travel from Columbia, MO to Indianapolis via St. Louis, MO, you can save more than $28? You can find the corresponding connections below.
    • Greyhound US
      9h 50m
      0
      8:35 PM
      Columbia, MO
      Red Thread
      10:55 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $23
      • Waiting Time 3h 5m
    • Greyhound US
      4h 25m
      0
      2:00 AM
      St. Louis, MO
      Gateway Station
      7:25 AM
      Indianapolis
      Central Bus Station
      0
      Greyhound US
      Economy
      $32
    Travel Time is 1h 0m shorter, and you will save $28

Best Price Offer: The price for the cheapest bus from Columbia, MO to Indianapolis is $83 on 6/22/2026. Flexible travelers save on ticket prices.


Facts about the bus from Columbia, MO to Indianapolis

Compare all providers like Greyhound US that travel 12 times every day by bus from Columbia, MO to Indianapolis in one click! Book your bus ticket from Columbia, MO to Indianapolis starting from $83!

Cheapest Bus $83
Fastest Bus 8h 40m
Earliest Bus 8:30 AM
Latest Bus 8:35 PM
Daily Bus Routes 12 Ø
Distance 334.5 miles
Bus Companies Greyhound US

Cheapest bus connections from Columbia, MO to Indianapolis

Every day, 12 buses from 1 bus companies leave Columbia, MO for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/21
Monday 06/22
$83
Tuesday 06/23
Wednesday 06/24
Thursday 06/25
Friday 06/26
Saturday 06/27
Sunday 06/28
Monday 06/29
Tuesday 06/30
Wednesday 07/01
Thursday 07/02
Friday 07/03
Saturday 07/04
Sunday 07/05
Monday 07/06
Tuesday 07/07
Wednesday 07/08
Thursday 07/09
Friday 07/10
Saturday 07/11
Sunday 07/12
Monday 07/13
Tuesday 07/14
Wednesday 07/15
Thursday 07/16
Friday 07/17
Saturday 07/18

How to save money travelling from Columbia, MO to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Columbia, MO to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Columbia, MO to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Columbia, MO to Indianapolis are also emptier.

All bus stations and stops in Columbia, MO and Indianapolis

In the map below, you can see where to find all bus stations in Columbia, MO and Indianapolis.

Service and Comfort on the bus from Columbia, MO to Indianapolis

Want to know which seat classes are available on the buses from Columbia, MO to Indianapolis? Or which bus companies serve the route Columbia, MO to Indianapolis? Below you will find answers to your questions.

FAQs about the Columbia, MO to Indianapolis bus

How much does a Columbia, MO Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $83 and takes 10h 50m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from Columbia, MO to Indianapolis?

This route is offered by 1 companies with a range of ticket prices between $83 and $143. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from Columbia, MO to Indianapolis each day?

Every day, the Columbia, MO to Indianapolis bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Columbia, MO to Indianapolis take?

The fastest bus from Columbia, MO to Indianapolis is offered by Greyhound US and takes 8h 40m. Bus tickets for this connection cost $143. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Columbia, MO to Indianapolis?

The earliest bus arriving in Indianapolis from Columbia, MO starts at 8:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Columbia, MO to Indianapolis?

The latest bus trip departing from Columbia, MO for Indianapolis starts at 8:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Columbia, MO Indianapolis route?

When traveling by bus from Columbia, MO to Indianapolis, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Columbia, MO and Indianapolis?

You can check all the direct connections between Columbia, MO and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Columbia, MO to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Columbia, MO Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Columbia, MO Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Columbia, MO to Indianapolis on your planned travel date.

How does CheckMyBus find the best bus deals from Columbia, MO to Indianapolis?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 12 daily trips between Columbia, MO and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Columbia, MO to Indianapolis?

Prices and availability for 12 trips between Columbia, MO and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Columbia, MO to Indianapolis

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Columbia, MO and to Indianapolis

Here’s an overview of the most popular bus routes to Columbia, MO and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!
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