Bus Houston to Winston-Salem, NC - Compare all Companies

Compare all timetables for the bus from Houston to Winston-Salem, NC

Here is a selection of the cheapest bus trips from the schedule from Houston to Winston-Salem, NC from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today

$150

tomorrow

Wednesday

Thursday

Friday

Saturday

$153

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	31h 45m	10:00 PM	Houston	Harrisburg Blvd Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$150	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 1/19/2026 10:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 1/21/2026 6:45:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 31h 45m
FlixBus	41h 55m	7:50 PM	Houston	Uptown/Upper Kirby	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$150	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 1/19/2026 7:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 1/21/2026 2:45:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 41h 55m
Greyhound US	24h 40m	1:05 PM	Houston	Harrisburg Blvd Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$151	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 1/19/2026 1:05:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 1/20/2026 2:45:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 24h 40m
FlixBus	36h 25m	5:35 PM	Houston	Uptown/Upper Kirby	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$151	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 1/19/2026 5:35:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 1/21/2026 7:00:00 AM. 50 Economy ticket for $151 per person are available. Travel duration is 36h 25m
FlixBus	24h 30m	1:15 PM	Houston	Uptown/Upper Kirby	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$152	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 1/19/2026 1:15:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 1/20/2026 2:45:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 24h 30m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 0m	5:00 AM	Houston	Harrisburg Blvd Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$153	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 1/24/2026 5:00:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 1/25/2026 7:00:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 25h 0m
Greyhound Lines Mexico	44h 30m	9:30 AM	Houston	SW Agencia Autobuses	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$153	A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 1/24/2026 9:30:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 1/26/2026 7:00:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 44h 30m
FlixBus	36h 25m	5:35 PM	Houston	Uptown/Upper Kirby	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$153	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 1/24/2026 5:35:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 1/26/2026 7:00:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 36h 25m
FlixBus	31h 10m	10:50 PM	Houston	Downtown Houston	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$153	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 1/24/2026 10:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 1/26/2026 7:00:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 31h 10m
Greyhound US	31h 45m	10:00 PM	Houston	Harrisburg Blvd Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$154	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 1/24/2026 10:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 1/26/2026 6:45:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 31h 45m

Did you know that if you travel from Houston to Winston-Salem, NC via Atlanta, GA, you can save more than $33? You can find the corresponding connections below.
- FlixBus
  
  25h 0m
  
  0
  
  5:00 AM
  
  Houston
  Harrisburg Blvd Station
  
  10:55 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $72
  
  A Bus from FlixBus goes from Harrisburg Blvd Station, Houston (USA) at 1/26/2026 5:00:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 1/26/2026 10:55:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 16h 55m
- FlixBus
  
  6h 20m
  
  0
  
  12:40 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  7:00 AM
  
  Winston-Salem, NC
  Greyhound Bus Station
  
  0
  
  Economy
  
  $48
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 1/27/2026 12:40:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 1/27/2026 7:00:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 6h 20m
Travel Time is 1h 0m shorter, and you will save $33

Best Price Offer: The price for the cheapest bus from Houston to Winston-Salem, NC is $139 on 1/27/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Houston and Winston-Salem, NC

See here how frequent the connections between Houston and Winston-Salem, NC are, during different times and days of the week.

Saturday is the busiest day, with more than 11 daily buses from Houston to Winston-Salem, NC. Monday has instead the fewest connections, with only 8 daily coaches between Houston and Winston-Salem, NC.

The busiest time of the day is the Afternoon, with 11 buses from Houston to Winston-Salem, NC, while Morning sees the fewest connections between Houston and Winston-Salem, NC, with 1 offers.

Facts about the bus from Houston to Winston-Salem, NC

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 9 times every day by bus from Houston to Winston-Salem, NC in one click! Book your bus ticket from Houston to Winston-Salem, NC starting from $139!

Cheapest Bus	$139
Fastest Bus	25h 0m
Earliest Bus	1:05 PM
Latest Bus	10:50 PM
Daily Bus Routes	9 Ø
Distance	979.6 miles
Bus Companies	FlixBus, Greyhound US and Greyhound Lines Mexico

Cheapest bus connections from Houston to Winston-Salem, NC

Every day, 9 buses from 3 bus companies leave Houston for Winston-Salem, NC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

$150

Tuesday 01/20

Wednesday 01/21

Thursday 01/22

Friday 01/23

Saturday 01/24

$153

Sunday 01/25

Monday 01/26

Tuesday 01/27

$139

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

The cheapest time to travel from Houston to Winston-Salem, NC

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to Winston-Salem, NC, for the next 30 days.

With a price starting from $150, Monday is the cheapest day for a bus from Houston to Winston-Salem, NC. Saturday instead is the most expensive day with prices starting from $153.

Night is the cheapest day time for bus tickets from Houston to Winston-Salem, NC, with $139. Morning is the most expensive time of the day with prices starting from $152.

How to save money travelling from Houston to Winston-Salem, NC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to Winston-Salem, NC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to Winston-Salem, NC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to Winston-Salem, NC are also emptier.

All bus stations and stops in Houston and Winston-Salem, NC

In the map below, you can see where to find all bus stations in Houston and Winston-Salem, NC.

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Uptown/Upper Kirby

Southwest Fwy 2525

Chase Bank

Milam Street 212

Greyhound Bus Station

W 5th St 100

Hong Kong King Buffet

Silas Creek Pkwy 1237

Forsyth Hospital

Silas Creek Pkwy 3333

E Sprague St

E Sprague St 841

Hicks St.

Service and Comfort on the bus from Houston to Winston-Salem, NC

Want to know which seat classes are available on the buses from Houston to Winston-Salem, NC? Or which bus companies serve the route Houston to Winston-Salem, NC? Below you will find answers to your questions.

FAQs about the Houston to Winston-Salem, NC bus

How much does a Houston Winston-Salem, NC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $139 and takes 42h 55m to reach Winston-Salem, NC. Compare offers to save money!

How much could I save by comparing buses from Houston to Winston-Salem, NC?

This route is offered by 3 companies with a range of ticket prices between $139 and $171. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Winston-Salem, NC.

On average, how many connections are available from Houston to Winston-Salem, NC each day?

Every day, the Houston to Winston-Salem, NC bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to Winston-Salem, NC take?

The fastest bus from Houston to Winston-Salem, NC is offered by FlixBus and takes 25h 0m. Bus tickets for this connection cost $152. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to Winston-Salem, NC?

The earliest bus arriving in Winston-Salem, NC from Houston starts at 1:05 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to Winston-Salem, NC?

The latest bus trip departing from Houston for Winston-Salem, NC starts at 10:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston Winston-Salem, NC route?

When traveling by bus from Houston to Winston-Salem, NC, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and Winston-Salem, NC?

You can check all the direct connections between Houston and Winston-Salem, NC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the Houston to Winston-Salem, NC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston Winston-Salem, NC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston Winston-Salem, NC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to Winston-Salem, NC on your planned travel date.

How does CheckMyBus find the best bus deals from Houston to Winston-Salem, NC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Houston and Winston-Salem, NC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Houston to Winston-Salem, NC?

Prices and availability for 9 trips between Houston and Winston-Salem, NC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Houston to Winston-Salem, NC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to Winston-Salem, NC

Here’s an overview of the most popular bus routes to Houston and to Winston-Salem, NC. Simply click on the connection of your choice, and you will find all the details about your bus route!