Bus Indianapolis to Cambridge, MA: Compare prices and save money

Compare all timetables for the bus from Indianapolis to Cambridge, MA

Here is a selection of the cheapest bus trips from the schedule from Indianapolis to Cambridge, MA from various bus operators like FlixBus or Greyhound US for the next days.

today

$183

tomorrow

Friday

$194

Saturday

$177

Sunday

$167

Monday

$143

Tuesday

$138

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	27h 45m	3:35 PM	Indianapolis	Central Bus Station	7:20 PM	Cambridge, MA	Alewife Station		Economy	$183	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 12/17/2025 3:35:00 PM to Alewife Station, Cambridge, MA (USA) arriving at 12/18/2025 7:20:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 27h 45m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 0m	4:20 PM	Indianapolis	Downtown Transit Center	7:20 PM	Cambridge, MA	Alewife Station	Economy	$194	A Bus from FlixBus goes from Downtown Transit Center, Indianapolis (USA) at 12/19/2025 4:20:00 PM to Alewife Station, Cambridge, MA (USA) arriving at 12/20/2025 7:20:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 27h 0m
Greyhound US	27h 45m	3:35 PM	Indianapolis	Central Bus Station	7:20 PM	Cambridge, MA	Alewife Station	Economy	$195	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 12/19/2025 3:35:00 PM to Alewife Station, Cambridge, MA (USA) arriving at 12/20/2025 7:20:00 PM. 50 Economy ticket for $195 per person are available. Travel duration is 27h 45m
FlixBus	38h 30m	12:15 AM	Indianapolis	Washington / Delaware	2:45 PM	Cambridge, MA	Alewife Station	Economy	$204	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 12/19/2025 12:15:00 AM to Alewife Station, Cambridge, MA (USA) arriving at 12/20/2025 2:45:00 PM. 50 Economy ticket for $204 per person are available. Travel duration is 38h 30m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 45m	3:35 PM	Indianapolis	Central Bus Station	7:20 PM	Cambridge, MA	Alewife Station	Economy	$177	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 12/20/2025 3:35:00 PM to Alewife Station, Cambridge, MA (USA) arriving at 12/21/2025 7:20:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 27h 45m
FlixBus	27h 0m	4:20 PM	Indianapolis	Downtown Transit Center	7:20 PM	Cambridge, MA	Alewife Station	Economy	$178	A Bus from FlixBus goes from Downtown Transit Center, Indianapolis (USA) at 12/20/2025 4:20:00 PM to Alewife Station, Cambridge, MA (USA) arriving at 12/21/2025 7:20:00 PM. 50 Economy ticket for $178 per person are available. Travel duration is 27h 0m
FlixBus	38h 30m	12:15 AM	Indianapolis	Washington / Delaware	2:45 PM	Cambridge, MA	Alewife Station	Economy	$293	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 12/20/2025 12:15:00 AM to Alewife Station, Cambridge, MA (USA) arriving at 12/21/2025 2:45:00 PM. 50 Economy ticket for $293 per person are available. Travel duration is 38h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 0m	4:20 PM	Indianapolis	Downtown Transit Center	7:20 PM	Cambridge, MA	Alewife Station	Economy	$167	A Bus from FlixBus goes from Downtown Transit Center, Indianapolis (USA) at 12/21/2025 4:20:00 PM to Alewife Station, Cambridge, MA (USA) arriving at 12/22/2025 7:20:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 27h 0m
Greyhound US	27h 45m	3:35 PM	Indianapolis	Central Bus Station	7:20 PM	Cambridge, MA	Alewife Station	Economy	$167	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 12/21/2025 3:35:00 PM to Alewife Station, Cambridge, MA (USA) arriving at 12/22/2025 7:20:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 27h 45m
FlixBus	38h 30m	12:15 AM	Indianapolis	Washington / Delaware	2:45 PM	Cambridge, MA	Alewife Station	Economy	$197	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 12/21/2025 12:15:00 AM to Alewife Station, Cambridge, MA (USA) arriving at 12/22/2025 2:45:00 PM. 50 Economy ticket for $197 per person are available. Travel duration is 38h 30m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 45m	3:35 PM	Indianapolis	Central Bus Station	7:20 PM	Cambridge, MA	Alewife Station	Economy	$143	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 12/22/2025 3:35:00 PM to Alewife Station, Cambridge, MA (USA) arriving at 12/23/2025 7:20:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 27h 45m
FlixBus	27h 0m	4:20 PM	Indianapolis	Downtown Transit Center	7:20 PM	Cambridge, MA	Alewife Station	Economy	$145	A Bus from FlixBus goes from Downtown Transit Center, Indianapolis (USA) at 12/22/2025 4:20:00 PM to Alewife Station, Cambridge, MA (USA) arriving at 12/23/2025 7:20:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 27h 0m
FlixBus	38h 30m	12:15 AM	Indianapolis	Downtown Transit Center	2:45 PM	Cambridge, MA	Alewife Station	Economy	$156	A Bus from FlixBus goes from Downtown Transit Center, Indianapolis (USA) at 12/22/2025 12:15:00 AM to Alewife Station, Cambridge, MA (USA) arriving at 12/23/2025 2:45:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 38h 30m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 0m	4:20 PM	Indianapolis	Downtown Transit Center	7:20 PM	Cambridge, MA	Alewife Station	Economy	$138	A Bus from FlixBus goes from Downtown Transit Center, Indianapolis (USA) at 12/23/2025 4:20:00 PM to Alewife Station, Cambridge, MA (USA) arriving at 12/24/2025 7:20:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 27h 0m
Greyhound US	27h 45m	3:35 PM	Indianapolis	Central Bus Station	7:20 PM	Cambridge, MA	Alewife Station	Economy	$140	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 12/23/2025 3:35:00 PM to Alewife Station, Cambridge, MA (USA) arriving at 12/24/2025 7:20:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 27h 45m
FlixBus	38h 30m	12:15 AM	Indianapolis	Downtown Transit Center	2:45 PM	Cambridge, MA	Alewife Station	Economy	$162	A Bus from FlixBus goes from Downtown Transit Center, Indianapolis (USA) at 12/23/2025 12:15:00 AM to Alewife Station, Cambridge, MA (USA) arriving at 12/24/2025 2:45:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 38h 30m

Best Price Offer: The price for the cheapest bus from Indianapolis to Cambridge, MA is $114 on 1/8/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Indianapolis and Cambridge, MA

See here how frequent the connections between Indianapolis and Cambridge, MA are, during different times and days of the week.

Sunday is the busiest day, with more than 6 daily buses from Indianapolis to Cambridge, MA. Wednesday has instead the fewest connections, with only 2 daily coaches between Indianapolis and Cambridge, MA.

The busiest time of the day is the Afternoon, with 22 buses from Indianapolis to Cambridge, MA, while Night sees the fewest connections between Indianapolis and Cambridge, MA, with 10 offers.

Facts about the bus from Indianapolis to Cambridge, MA

Compare all providers like FlixBus and Greyhound US that travel 5 times every day by bus from Indianapolis to Cambridge, MA in one click! Book your bus ticket from Indianapolis to Cambridge, MA starting from $114!

Cheapest Bus	$114
Fastest Bus	27h 0m
Earliest Bus	3:35 PM
Latest Bus	4:20 PM
Daily Bus Routes	5 Ø
Distance	803.1 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Indianapolis to Cambridge, MA

Every day, 5 buses from 2 bus companies leave Indianapolis for Cambridge, MA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/17/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

$183

Thursday 12/18

Friday 12/19

$194

Saturday 12/20

$177

Sunday 12/21

$178

Monday 12/22

$143

Tuesday 12/23

$138

Wednesday 12/24

$148

Thursday 12/25

$146

Friday 12/26

Saturday 12/27

$150

Sunday 12/28

$182

Monday 12/29

$157

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

$148

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

$114

Friday 01/09

Saturday 01/10

The cheapest time to travel from Indianapolis to Cambridge, MA

See here on which day and which time of the day you can find the cheapest bus ticket from Indianapolis to Cambridge, MA, for the next 30 days.

With a price starting from $112, Sunday is the cheapest day for a bus from Indianapolis to Cambridge, MA. Friday instead is the most expensive day with prices starting from $194.

Night is the cheapest day time for bus tickets from Indianapolis to Cambridge, MA, with $112. Afternoon is the most expensive time of the day with prices starting from $138.

How to save money travelling from Indianapolis to Cambridge, MA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Indianapolis to Cambridge, MA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Indianapolis to Cambridge, MA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Indianapolis to Cambridge, MA are also emptier.

All bus stations and stops in Indianapolis and Cambridge, MA

In the map below, you can see where to find all bus stations in Indianapolis and Cambridge, MA.

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Central Bus Station

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

Alewife Station

Rindge Ave 351

Service and Comfort on the bus from Indianapolis to Cambridge, MA

Want to know which seat classes are available on the buses from Indianapolis to Cambridge, MA? Or which bus companies serve the route Indianapolis to Cambridge, MA? Below you will find answers to your questions.

FAQs about the Indianapolis to Cambridge, MA bus

How much does a Indianapolis Cambridge, MA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $114 and takes 27h 0m to reach Cambridge, MA. Compare offers to save money!

How much could I save by comparing buses from Indianapolis to Cambridge, MA?

This route is offered by 2 companies with a range of ticket prices between $114 and $324. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Cambridge, MA.

On average, how many connections are available from Indianapolis to Cambridge, MA each day?

Every day, the Indianapolis to Cambridge, MA bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Indianapolis to Cambridge, MA take?

The fastest bus from Indianapolis to Cambridge, MA is offered by FlixBus and takes 27h 0m. Bus tickets for this connection cost $237. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Indianapolis to Cambridge, MA?

The earliest bus arriving in Cambridge, MA from Indianapolis starts at 3:35 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Indianapolis to Cambridge, MA?

The latest bus trip departing from Indianapolis for Cambridge, MA starts at 4:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Indianapolis Cambridge, MA route?

When traveling by bus from Indianapolis to Cambridge, MA, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Indianapolis and Cambridge, MA?

You can check all the direct connections between Indianapolis and Cambridge, MA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Indianapolis to Cambridge, MA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Indianapolis Cambridge, MA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Indianapolis Cambridge, MA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Indianapolis to Cambridge, MA on your planned travel date.

How does CheckMyBus find the best bus deals from Indianapolis to Cambridge, MA?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Indianapolis and Cambridge, MA. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Indianapolis to Cambridge, MA?

Prices and availability for 5 trips between Indianapolis and Cambridge, MA change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Indianapolis to Cambridge, MA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Indianapolis and to Cambridge, MA

Here’s an overview of the most popular bus routes to Indianapolis and to Cambridge, MA. Simply click on the connection of your choice, and you will find all the details about your bus route!