Bus Indianapolis to Tupelo, MS - Compare all Companies

Compare all timetables for the bus from Indianapolis to Tupelo, MS

Here is a selection of the cheapest bus trips from the schedule from Indianapolis to Tupelo, MS from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

Thursday

Friday

Saturday

$91

Sunday

Monday

$84

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 5m	11:30 PM	Indianapolis	Washington / Delaware	9:35 PM	Tupelo, MS	Bus Stop	Economy	$91	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/9/2026 11:30:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 5/10/2026 9:35:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 23h 5m
FlixBus	20h 50m	3:15 AM	Indianapolis	Washington / Delaware	11:05 PM	Tupelo, MS	Bus Stop	Economy	$92	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/9/2026 3:15:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 5/9/2026 11:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 20h 50m
FlixBus	17h 15m	6:25 PM	Indianapolis	Washington / Delaware	10:40 AM	Tupelo, MS	Bus Stop	Economy	$92	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/9/2026 6:25:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 5/10/2026 10:40:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 17h 15m
Greyhound US	13h 0m	11:05 AM	Indianapolis	Central Bus Station	11:05 PM	Tupelo, MS	Bus Stop	Economy	$92	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 5/9/2026 11:05:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 5/9/2026 11:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 13h 0m
Greyhound US	19h 10m	11:15 AM	Indianapolis	Central Bus Station	5:25 AM	Tupelo, MS	Bus Stop	Economy	$93	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 5/9/2026 11:15:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 5/10/2026 5:25:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 19h 10m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 50m	3:15 AM	Indianapolis	Washington / Delaware	11:05 PM	Tupelo, MS	Bus Stop	Economy	$84	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/11/2026 3:15:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 5/11/2026 11:05:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 20h 50m
FlixBus	23h 5m	11:30 PM	Indianapolis	Washington / Delaware	9:35 PM	Tupelo, MS	Bus Stop	Economy	$84	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/11/2026 11:30:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 5/12/2026 9:35:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 23h 5m
FlixBus	17h 15m	6:25 PM	Indianapolis	Washington / Delaware	10:40 AM	Tupelo, MS	Bus Stop	Economy	$85	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 5/11/2026 6:25:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 5/12/2026 10:40:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 17h 15m
Greyhound US	13h 0m	11:05 AM	Indianapolis	Central Bus Station	11:05 PM	Tupelo, MS	Bus Stop	Economy	$85	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 5/11/2026 11:05:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 5/11/2026 11:05:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 13h 0m
Greyhound US	19h 10m	11:15 AM	Indianapolis	Central Bus Station	5:25 AM	Tupelo, MS	Bus Stop	Economy	$85	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 5/11/2026 11:15:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 5/12/2026 5:25:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 19h 10m

Best Price Offer: The price for the cheapest bus from Indianapolis to Tupelo, MS is $81 on 5/17/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Indianapolis and Tupelo, MS

See here how frequent the connections between Indianapolis and Tupelo, MS are, during different times and days of the week.

Monday is the busiest day, with more than 6 daily buses from Indianapolis to Tupelo, MS. Monday has instead the fewest connections, with only 6 daily coaches between Indianapolis and Tupelo, MS.

The busiest time of the day is the Evening, with 6 buses from Indianapolis to Tupelo, MS, while Night sees the fewest connections between Indianapolis and Tupelo, MS, with 2 offers.

Facts about the bus from Indianapolis to Tupelo, MS

Compare all providers like FlixBus and Greyhound US that travel 6 times every day by bus from Indianapolis to Tupelo, MS in one click! Book your bus ticket from Indianapolis to Tupelo, MS starting from $81!

Cheapest Bus	$81
Fastest Bus	12h 0m
Earliest Bus	3:15 AM
Latest Bus	11:30 PM
Daily Bus Routes	6 Ø
Distance	405.9 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Indianapolis to Tupelo, MS

Every day, 6 buses from 2 bus companies leave Indianapolis for Tupelo, MS: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/05/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/03

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

Saturday 05/09

$91

Sunday 05/10

Monday 05/11

$84

Tuesday 05/12

Wednesday 05/13

Thursday 05/14

Friday 05/15

$87

Saturday 05/16

Sunday 05/17

$81

Monday 05/18

$82

Tuesday 05/19

$88

Wednesday 05/20

$94

Thursday 05/21

Friday 05/22

Saturday 05/23

$102

Sunday 05/24

$100

Monday 05/25

Tuesday 05/26

Wednesday 05/27

$99

Thursday 05/28

Friday 05/29

$93

Saturday 05/30

The cheapest time to travel from Indianapolis to Tupelo, MS

See here on which day and which time of the day you can find the cheapest bus ticket from Indianapolis to Tupelo, MS, for the next 30 days.

With a price starting from $82, Monday is the cheapest day for a bus from Indianapolis to Tupelo, MS. Saturday instead is the most expensive day with prices starting from $91.

Night is the cheapest day time for bus tickets from Indianapolis to Tupelo, MS, with $81. Morning is the most expensive time of the day with prices starting from $85.

How to save money travelling from Indianapolis to Tupelo, MS

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Indianapolis to Tupelo, MS in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Indianapolis to Tupelo, MS, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Indianapolis to Tupelo, MS are also emptier.

All bus stations and stops in Indianapolis and Tupelo, MS

In the map below, you can see where to find all bus stations in Indianapolis and Tupelo, MS.

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Central Bus Station

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

Bus Stop

S Eason Blvd 2831

Service and Comfort on the bus from Indianapolis to Tupelo, MS

Want to know which seat classes are available on the buses from Indianapolis to Tupelo, MS? Or which bus companies serve the route Indianapolis to Tupelo, MS? Below you will find answers to your questions.

FAQs about the Indianapolis to Tupelo, MS bus

How much does a Indianapolis Tupelo, MS bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $81 and takes 19h 50m to reach Tupelo, MS. Compare offers to save money!

How much could I save by comparing buses from Indianapolis to Tupelo, MS?

This route is offered by 2 companies with a range of ticket prices between $81 and $93. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Tupelo, MS.

On average, how many connections are available from Indianapolis to Tupelo, MS each day?

Every day, the Indianapolis to Tupelo, MS bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Indianapolis to Tupelo, MS take?

The fastest bus from Indianapolis to Tupelo, MS is offered by Greyhound US and takes 12h 0m. Bus tickets for this connection cost $92. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Indianapolis to Tupelo, MS?

The earliest bus arriving in Tupelo, MS from Indianapolis starts at 3:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Indianapolis to Tupelo, MS?

The latest bus trip departing from Indianapolis for Tupelo, MS starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Indianapolis Tupelo, MS route?

When traveling by bus from Indianapolis to Tupelo, MS, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Indianapolis and Tupelo, MS?

You can check all the direct connections between Indianapolis and Tupelo, MS by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Indianapolis to Tupelo, MS bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Indianapolis Tupelo, MS bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Indianapolis Tupelo, MS bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Indianapolis to Tupelo, MS on your planned travel date.

How does CheckMyBus find the best bus deals from Indianapolis to Tupelo, MS?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Indianapolis and Tupelo, MS. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Indianapolis to Tupelo, MS?

Prices and availability for 6 trips between Indianapolis and Tupelo, MS change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Indianapolis to Tupelo, MS

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Indianapolis and to Tupelo, MS

Here’s an overview of the most popular bus routes to Indianapolis and to Tupelo, MS. Simply click on the connection of your choice, and you will find all the details about your bus route!