Bus from Jacksonville, FL to Chicago from $125

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Compare all timetables for the bus from Jacksonville, FL to Chicago

Here is a selection of the cheapest bus trips from the schedule from Jacksonville, FL to Chicago from various bus operators like FlixBus or Greyhound US for the next days.

today
tomorrow
$210
Sunday
$138
Monday
Tuesday
$177
Wednesday
Thursday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 55m 9:05 AM Jacksonville, FL Amtrak Train Station 8:00 AM Chicago Union Station  Economy $210
FlixBus 24h 20m 9:05 AM Jacksonville, FL Amtrak Train Station 8:25 AM Chicago Downtown Bus Station  Economy $210
FlixBus 23h 45m 4:30 PM Jacksonville, FL Amtrak Train Station 3:15 PM Chicago Downtown Bus Station  Economy $210
Greyhound US 27h 0m 9:30 AM Jacksonville, FL Amtrak Train Station 11:30 AM Chicago Downtown Bus Station  Economy $210
Greyhound US 29h 40m 9:30 AM Jacksonville, FL Amtrak Train Station 2:10 PM Chicago Union Station  Economy $212
  • Did you know that if you travel from Jacksonville, FL to Chicago via Atlanta, GA, you can save more than $75? You can find the corresponding connections below.
    • FlixBus
      23h 45m
      0
      9:25 PM
      Jacksonville, FL
      Amtrak Train Station
      4:10 AM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $50
      • Waiting Time 0h 55m
    • Busbud
      16h 5m
      0
      5:05 AM
      Atlanta, GA
      Garnett Transit Station
      8:10 PM
      Chicago
      Downtown Bus Station
      0
      Busbud
      Economy
      $85
    Travel time is 1h 0m longer, but you will save $75

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 35h 35m 11:15 PM Jacksonville, FL Amtrak Train Station 9:50 AM Chicago 95th Red Line Station  Economy $138
FlixBus 25h 45m 9:05 AM Jacksonville, FL Amtrak Train Station 9:50 AM Chicago 95th Red Line Station  Economy $139
FlixBus 27h 10m 9:25 PM Jacksonville, FL Amtrak Train Station 11:35 PM Chicago 95th Red Line Station  Economy $139
Greyhound US 26h 35m 9:30 AM Jacksonville, FL Amtrak Train Station 11:05 AM Chicago 95th Red Line Station  Economy $139
Greyhound US 27h 0m 9:30 AM Jacksonville, FL Amtrak Train Station 11:30 AM Chicago Downtown Bus Station  Economy $145

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 45m 9:25 PM Jacksonville, FL Amtrak Train Station 8:10 PM Chicago Downtown Bus Station  Economy $177
FlixBus 33h 45m 11:15 PM Jacksonville, FL Amtrak Train Station 8:00 AM Chicago Union Station  Economy $184
FlixBus 34h 10m 11:15 PM Jacksonville, FL Amtrak Train Station 8:25 AM Chicago Downtown Bus Station  Economy $184
Greyhound US 27h 0m 9:30 AM Jacksonville, FL Amtrak Train Station 11:30 AM Chicago Downtown Bus Station  Economy $185
Greyhound US 29h 40m 9:30 AM Jacksonville, FL Amtrak Train Station 2:10 PM Chicago Union Station  Economy $187
  • Did you know that if you travel from Jacksonville, FL to Chicago via Atlanta, GA, you can save more than $42? You can find the corresponding connections below.
    • FlixBus
      23h 45m
      0
      9:25 PM
      Jacksonville, FL
      Amtrak Train Station
      4:10 AM
      Atlanta, GA
      Garnett Transit Station
      0
      FlixBus
      Economy
      $50
      • Waiting Time 0h 55m
    • Busbud
      16h 5m
      0
      5:05 AM
      Atlanta, GA
      Garnett Transit Station
      8:10 PM
      Chicago
      Downtown Bus Station
      0
      Busbud
      Economy
      $85
    Travel time is 1h 0m longer, but you will save $42

Best Price Offer: The price for the cheapest bus from Jacksonville, FL to Chicago is $125 on 2/13/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Jacksonville, FL and Chicago

See here how frequent the connections between Jacksonville, FL and Chicago are, during different times and days of the week.
Sunday is the busiest day, with more than 13 daily buses from Jacksonville, FL to Chicago. Tuesday has instead the fewest connections, with only 7 daily coaches between Jacksonville, FL and Chicago.
The busiest time of the day is the Morning, with 14 buses from Jacksonville, FL to Chicago, while Afternoon sees the fewest connections between Jacksonville, FL and Chicago, with 3 offers.

Facts about the bus from Jacksonville, FL to Chicago

Compare all providers like FlixBus and Greyhound US that travel 9 times every day by bus from Jacksonville, FL to Chicago in one click! Book your bus ticket from Jacksonville, FL to Chicago starting from $125!

Cheapest Bus $125
Fastest Bus 22h 45m
Earliest Bus 9:05 AM
Latest Bus 11:15 PM
Daily Bus Routes 9 Ø
Distance 864.3 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Jacksonville, FL to Chicago

Every day, 9 buses from 2 bus companies leave Jacksonville, FL for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
Friday 02/06
Saturday 02/07
$210
Sunday 02/08
$138
Monday 02/09
Tuesday 02/10
$177
Wednesday 02/11
Thursday 02/12
Friday 02/13
$125
Saturday 02/14
Sunday 02/15
Monday 02/16
Tuesday 02/17
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
Sunday 02/22
Monday 02/23
Tuesday 02/24
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28

The cheapest time to travel from Jacksonville, FL to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Jacksonville, FL to Chicago, for the next 30 days.
With a price starting from $138, Sunday is the cheapest day for a bus from Jacksonville, FL to Chicago. Saturday instead is the most expensive day with prices starting from $210.
Evening is the cheapest day time for bus tickets from Jacksonville, FL to Chicago, with $138. Afternoon is the most expensive time of the day with prices starting from $140.

How to save money travelling from Jacksonville, FL to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Jacksonville, FL to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Jacksonville, FL to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Jacksonville, FL to Chicago are also emptier.

Beloved bus companies from Jacksonville, FL to Chicago

These are the most booked bus companies between Jacksonville, FL to Chicago from our users.

Greyhound US from Jacksonville, FL to Chicago

Greyhound US

Here you will find the key facts about the Greyhound US bus route Jacksonville, FL to Chicago:

Cheapest Price $139
Fastest Bus 25h 35m
Earliest Bus 9:30 AM
Last Bus 9:30 AM
Daily Connections 2 Ø
Found on 2/1/2026

All bus stations and stops in Jacksonville, FL and Chicago

In the map below, you can see where to find all bus stations in Jacksonville, FL and Chicago.

Service and Comfort on the bus from Jacksonville, FL to Chicago

Want to know which seat classes are available on the buses from Jacksonville, FL to Chicago? Or which bus companies serve the route Jacksonville, FL to Chicago? Below you will find answers to your questions.

FAQs about the Jacksonville, FL to Chicago bus

How much does a Jacksonville, FL Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $125 and takes 34h 35m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Jacksonville, FL to Chicago?

This route is offered by 2 companies with a range of ticket prices between $125 and $212. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Jacksonville, FL to Chicago each day?

Every day, the Jacksonville, FL to Chicago bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Jacksonville, FL to Chicago take?

The fastest bus from Jacksonville, FL to Chicago is offered by FlixBus and takes 22h 45m. Bus tickets for this connection cost $210. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Jacksonville, FL to Chicago?

The earliest bus arriving in Chicago from Jacksonville, FL starts at 9:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Jacksonville, FL to Chicago?

The latest bus trip departing from Jacksonville, FL for Chicago starts at 11:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Jacksonville, FL Chicago route?

When traveling by bus from Jacksonville, FL to Chicago, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Jacksonville, FL and Chicago?

You can check all the direct connections between Jacksonville, FL and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Jacksonville, FL to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Jacksonville, FL Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Jacksonville, FL Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Jacksonville, FL to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Jacksonville, FL to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Jacksonville, FL and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Jacksonville, FL to Chicago?

Prices and availability for 9 trips between Jacksonville, FL and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Jacksonville, FL to Chicago

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Jacksonville, FL and to Chicago

Here’s an overview of the most popular bus routes to Jacksonville, FL and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus Fort Lauderdale, FL - Chicago Bus Fort Lauderdale, FL - Chicago
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Bus from Shreveport, LA to Chicago Bus from Shreveport, LA to Chicago
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Popular Airport Shuttles to Jacksonville, FL and to Chicago
CheckMyBus › Buses in USA › Bus to Jacksonville, FL › Bus to Chicago

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