Bus from Knoxville, TN to Cheyenne, WY from $221

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Compare all timetables for the bus from Knoxville, TN to Cheyenne, WY

Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to Cheyenne, WY from various bus operators like Greyhound US for the next days.

today
$228
tomorrow
Saturday
Sunday
$224
Monday
$228
Tuesday
$224
Wednesday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 62h 45m 10:50 PM Knoxville, TN Greyhound Bus Station 11:35 AM Cheyenne, WY Sinclair  Economy $228
Greyhound US 41h 55m 7:40 PM Knoxville, TN Greyhound Bus Station 11:35 AM Cheyenne, WY Sinclair  Economy $234
  • Did you know that if you travel from Knoxville, TN to Cheyenne, WY via St. Louis, MO, you can save more than $43? You can find the corresponding connections below.
    • Greyhound US
      43h 25m
      0
      6:10 PM
      Knoxville, TN
      Knoxville Area Transit Bus Stop
      3:10 PM
      St. Louis, MO
      Gateway Station
      0
      Greyhound US
      Economy
      $87
      • Waiting Time 1h 20m
    • Greyhound US
      20h 5m
      0
      4:30 PM
      St. Louis, MO
      Gateway Station
      11:35 AM
      Cheyenne, WY
      Roadway Inn
      0
      Greyhound US
      Economy
      $98
    Travel time is 3h 30m longer, but you will save $43

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 41h 55m 7:40 PM Knoxville, TN Greyhound Bus Station 11:35 AM Cheyenne, WY Sinclair  Economy $224
Greyhound US 62h 45m 10:50 PM Knoxville, TN Greyhound Bus Station 11:35 AM Cheyenne, WY Sinclair  Economy $226
  • Did you know that if you travel from Knoxville, TN to Cheyenne, WY via Denver, you can save more than $39? You can find the corresponding connections below.
    • Greyhound US
      41h 55m
      0
      7:40 PM
      Knoxville, TN
      Greyhound Bus Station
      8:45 AM
      Denver
      Union Station
      0
      Greyhound US
      Economy
      $162
      • Waiting Time 1h 0m
    • Greyhound US
      1h 50m
      0
      9:45 AM
      Denver
      Union Station
      11:35 AM
      Cheyenne, WY
      Roadway Inn
      0
      Greyhound US
      Economy
      $23
    Travel time is 2h 0m longer, but you will save $39

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 41h 55m 7:40 PM Knoxville, TN Greyhound Bus Station 11:35 AM Cheyenne, WY Sinclair  Economy $228
Greyhound US 62h 45m 10:50 PM Knoxville, TN Greyhound Bus Station 11:35 AM Cheyenne, WY Sinclair  Economy $229
  • Did you know that if you travel from Knoxville, TN to Cheyenne, WY via Denver, you can save more than $43? You can find the corresponding connections below.
    • Greyhound US
      41h 55m
      0
      7:40 PM
      Knoxville, TN
      Greyhound Bus Station
      8:45 AM
      Denver
      Union Station
      0
      Greyhound US
      Economy
      $162
      • Waiting Time 1h 0m
    • Greyhound US
      1h 50m
      0
      9:45 AM
      Denver
      Union Station
      11:35 AM
      Cheyenne, WY
      Roadway Inn
      0
      Greyhound US
      Economy
      $23
    Travel time is 2h 0m longer, but you will save $43

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 62h 45m 10:50 PM Knoxville, TN Greyhound Bus Station 11:35 AM Cheyenne, WY Sinclair  Economy $224
Greyhound US 41h 55m 7:40 PM Knoxville, TN Greyhound Bus Station 11:35 AM Cheyenne, WY Sinclair  Economy $233
  • Did you know that if you travel from Knoxville, TN to Cheyenne, WY via Denver, you can save more than $42? You can find the corresponding connections below.
    • Greyhound US
      43h 25m
      0
      6:10 PM
      Knoxville, TN
      Knoxville Area Transit Bus Stop
      7:50 AM
      Denver
      Union Station
      0
      Greyhound US
      Economy
      $163
      • Waiting Time 1h 55m
    • Greyhound US
      1h 50m
      0
      9:45 AM
      Denver
      Union Station
      11:35 AM
      Cheyenne, WY
      Sinclair
      0
      Greyhound US
      Economy
      $19
    Travel time is 3h 30m longer, but you will save $42

Best Price Offer: The price for the cheapest bus from Knoxville, TN to Cheyenne, WY is $221 on 6/16/2026. Flexible travelers save on ticket prices.


Facts about the bus from Knoxville, TN to Cheyenne, WY

Compare all providers like Greyhound US that travel 2 times every day by bus from Knoxville, TN to Cheyenne, WY in one click! Book your bus ticket from Knoxville, TN to Cheyenne, WY starting from $221!

Cheapest Bus $221
Fastest Bus 39h 55m
Earliest Bus 7:40 PM
Latest Bus 10:50 PM
Daily Bus Routes 2 Ø
Distance 1,181.9 miles
Bus Companies Greyhound US

Cheapest bus connections from Knoxville, TN to Cheyenne, WY

Every day, 2 buses from 1 bus companies leave Knoxville, TN for Cheyenne, WY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/04/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/31
Monday 06/01
Tuesday 06/02
Wednesday 06/03
Thursday 06/04
$228
Friday 06/05
Saturday 06/06
Sunday 06/07
$224
Monday 06/08
$228
Tuesday 06/09
$224
Wednesday 06/10
Thursday 06/11
Friday 06/12
$225
Saturday 06/13
Sunday 06/14
Monday 06/15
Tuesday 06/16
$221
Wednesday 06/17
Thursday 06/18
Friday 06/19
Saturday 06/20
Sunday 06/21
$221
Monday 06/22
$221
Tuesday 06/23
$225
Wednesday 06/24
$225
Thursday 06/25
$224
Friday 06/26
Saturday 06/27

How to save money travelling from Knoxville, TN to Cheyenne, WY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Knoxville, TN to Cheyenne, WY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Cheyenne, WY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Cheyenne, WY are also emptier.

All bus stations and stops in Knoxville, TN and Cheyenne, WY

In the map below, you can see where to find all bus stations in Knoxville, TN and Cheyenne, WY.

Service and Comfort on the bus from Knoxville, TN to Cheyenne, WY

Want to know which seat classes are available on the buses from Knoxville, TN to Cheyenne, WY? Or which bus companies serve the route Knoxville, TN to Cheyenne, WY? Below you will find answers to your questions.

FAQs about the Knoxville, TN to Cheyenne, WY bus

How much does a Knoxville, TN Cheyenne, WY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $221 and takes 60h 45m to reach Cheyenne, WY. Compare offers to save money!

How much could I save by comparing buses from Knoxville, TN to Cheyenne, WY?

This route is offered by 1 companies with a range of ticket prices between $221 and $234. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Cheyenne, WY.

On average, how many connections are available from Knoxville, TN to Cheyenne, WY each day?

Every day, the Knoxville, TN to Cheyenne, WY bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Knoxville, TN to Cheyenne, WY take?

The fastest bus from Knoxville, TN to Cheyenne, WY is offered by Greyhound US and takes 39h 55m. Bus tickets for this connection cost $234. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Knoxville, TN to Cheyenne, WY?

The earliest bus arriving in Cheyenne, WY from Knoxville, TN starts at 7:40 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Knoxville, TN to Cheyenne, WY?

The latest bus trip departing from Knoxville, TN for Cheyenne, WY starts at 10:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Knoxville, TN Cheyenne, WY route?

When traveling by bus from Knoxville, TN to Cheyenne, WY, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Knoxville, TN and Cheyenne, WY?

You can check all the direct connections between Knoxville, TN and Cheyenne, WY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Knoxville, TN to Cheyenne, WY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN Cheyenne, WY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Knoxville, TN Cheyenne, WY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to Cheyenne, WY on your planned travel date.

How does CheckMyBus find the best bus deals from Knoxville, TN to Cheyenne, WY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Knoxville, TN and Cheyenne, WY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Knoxville, TN to Cheyenne, WY?

Prices and availability for 2 trips between Knoxville, TN and Cheyenne, WY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Knoxville, TN to Cheyenne, WY

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Knoxville, TN and to Cheyenne, WY

Here’s an overview of the most popular bus routes to Knoxville, TN and to Cheyenne, WY. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Knoxville, TN and to Cheyenne, WY
CheckMyBus › Buses in USA › Bus to Knoxville, TN › Bus to Cheyenne, WY

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