Bus Knoxville, TN to Cheyenne, WY: Compare prices and save money

Compare all timetables for the bus from Knoxville, TN to Cheyenne, WY

Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to Cheyenne, WY from various bus operators like Greyhound US for the next days.

today

$224

tomorrow

$223

Wednesday

Thursday

Friday

Saturday

$221

Sunday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	41h 55m	7:40 PM	Knoxville, TN	Greyhound Bus Station	11:35 AM	Cheyenne, WY	Sinclair		Economy	$224	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 1/19/2026 7:40:00 PM to Sinclair, Cheyenne, WY (USA) arriving at 1/21/2026 11:35:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 41h 55m
	Greyhound US	62h 45m	10:50 PM	Knoxville, TN	Greyhound Bus Station	11:35 AM	Cheyenne, WY	Sinclair		Economy	$229	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 1/19/2026 10:50:00 PM to Sinclair, Cheyenne, WY (USA) arriving at 1/22/2026 11:35:00 AM. 50 Economy ticket for $229 per person are available. Travel duration is 62h 45m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	62h 45m	10:50 PM	Knoxville, TN	Greyhound Bus Station	11:35 AM	Cheyenne, WY	Sinclair		Economy	$223	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 1/20/2026 10:50:00 PM to Sinclair, Cheyenne, WY (USA) arriving at 1/23/2026 11:35:00 AM. 50 Economy ticket for $223 per person are available. Travel duration is 62h 45m
	Greyhound US	41h 55m	7:40 PM	Knoxville, TN	Greyhound Bus Station	11:35 AM	Cheyenne, WY	Sinclair		Economy	$224	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 1/20/2026 7:40:00 PM to Sinclair, Cheyenne, WY (USA) arriving at 1/22/2026 11:35:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 41h 55m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	41h 55m	7:40 PM	Knoxville, TN	Greyhound Bus Station	11:35 AM	Cheyenne, WY	Sinclair		Economy	$221	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 1/24/2026 7:40:00 PM to Sinclair, Cheyenne, WY (USA) arriving at 1/26/2026 11:35:00 AM. 50 Economy ticket for $221 per person are available. Travel duration is 41h 55m
	Greyhound US	62h 45m	10:50 PM	Knoxville, TN	Greyhound Bus Station	11:35 AM	Cheyenne, WY	Sinclair		Economy	$233	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 1/24/2026 10:50:00 PM to Sinclair, Cheyenne, WY (USA) arriving at 1/27/2026 11:35:00 AM. 50 Economy ticket for $233 per person are available. Travel duration is 62h 45m

Did you know that if you travel from Knoxville, TN to Cheyenne, WY via Indianapolis, you can save more than $28? You can find the corresponding connections below.
- FlixBus
  
  43h 25m
  
  0
  
  6:10 PM
  
  Knoxville, TN
  Greyhound Bus Station
  
  4:45 AM
  
  Indianapolis
  Central Bus Station
  
  0
  
  Economy
  
  $77
  
  A Bus from FlixBus goes from Greyhound Bus Station, Knoxville, TN (USA) at 1/24/2026 6:10:00 PM to Central Bus Station, Indianapolis (USA) arriving at 1/25/2026 4:45:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 10h 35m
- Busbud
  
  26h 10m
  
  0
  
  11:25 AM
  
  Indianapolis
  Central Bus Station
  
  11:35 AM
  
  Cheyenne, WY
  Roadway Inn
  
  0
  
  Economy
  
  $116
  
  A Bus from Busbud goes from Central Bus Station, Indianapolis (USA) at 1/25/2026 11:25:00 AM to Roadway Inn, Cheyenne, WY (USA) arriving at 1/26/2026 11:35:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 26h 10m
Travel time is 3h 30m longer, but you will save $28

Best Price Offer: The price for the cheapest bus from Knoxville, TN to Cheyenne, WY is $221 on 1/24/2026. Flexible travelers save on ticket prices.

Facts about the bus from Knoxville, TN to Cheyenne, WY

Compare all providers like Greyhound US that travel 2 times every day by bus from Knoxville, TN to Cheyenne, WY in one click! Book your bus ticket from Knoxville, TN to Cheyenne, WY starting from $221!

Cheapest Bus	$221
Fastest Bus	39h 55m
Earliest Bus	7:40 PM
Latest Bus	10:50 PM
Daily Bus Routes	2 Ø
Distance	1,181.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Knoxville, TN to Cheyenne, WY

Every day, 2 buses from 1 bus companies leave Knoxville, TN for Cheyenne, WY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

$224

Tuesday 01/20

$223

Wednesday 01/21

Thursday 01/22

Friday 01/23

Saturday 01/24

$221

Sunday 01/25

Monday 01/26

$229

Tuesday 01/27

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

How to save money travelling from Knoxville, TN to Cheyenne, WY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Knoxville, TN to Cheyenne, WY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Cheyenne, WY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Cheyenne, WY are also emptier.

All bus stations and stops in Knoxville, TN and Cheyenne, WY

In the map below, you can see where to find all bus stations in Knoxville, TN and Cheyenne, WY.

Kingston Pike

Kingston Pike 6927

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Greyhound Bus Station

E Magnolia Ave 100

Transit Center

E Church Ave 301

Sinclair

Roadway Inn

Walker Rd 5401

Service and Comfort on the bus from Knoxville, TN to Cheyenne, WY

Want to know which seat classes are available on the buses from Knoxville, TN to Cheyenne, WY? Or which bus companies serve the route Knoxville, TN to Cheyenne, WY? Below you will find answers to your questions.

FAQs about the Knoxville, TN to Cheyenne, WY bus

How much does a Knoxville, TN Cheyenne, WY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $221 and takes 39h 55m to reach Cheyenne, WY. Compare offers to save money!

How much could I save by comparing buses from Knoxville, TN to Cheyenne, WY?

This route is offered by 1 companies with a range of ticket prices between $221 and $233. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Cheyenne, WY.

On average, how many connections are available from Knoxville, TN to Cheyenne, WY each day?

Every day, the Knoxville, TN to Cheyenne, WY bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Knoxville, TN to Cheyenne, WY take?

The fastest bus from Knoxville, TN to Cheyenne, WY is offered by Greyhound US and takes 39h 55m. Bus tickets for this connection cost $224. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Knoxville, TN to Cheyenne, WY?

The earliest bus arriving in Cheyenne, WY from Knoxville, TN starts at 7:40 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Knoxville, TN to Cheyenne, WY?

The latest bus trip departing from Knoxville, TN for Cheyenne, WY starts at 10:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Knoxville, TN Cheyenne, WY route?

When traveling by bus from Knoxville, TN to Cheyenne, WY, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Knoxville, TN and Cheyenne, WY?

You can check all the direct connections between Knoxville, TN and Cheyenne, WY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Knoxville, TN to Cheyenne, WY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN Cheyenne, WY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Knoxville, TN Cheyenne, WY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to Cheyenne, WY on your planned travel date.

How does CheckMyBus find the best bus deals from Knoxville, TN to Cheyenne, WY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Knoxville, TN and Cheyenne, WY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Knoxville, TN to Cheyenne, WY?

Prices and availability for 2 trips between Knoxville, TN and Cheyenne, WY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Knoxville, TN to Cheyenne, WY

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Knoxville, TN and to Cheyenne, WY

Here’s an overview of the most popular bus routes to Knoxville, TN and to Cheyenne, WY. Simply click on the connection of your choice, and you will find all the details about your bus route!