Bus Lafayette, LA to Chicago: Compare prices and save money

Compare all timetables for the bus from Lafayette, LA to Chicago

Here is a selection of the cheapest bus trips from the schedule from Lafayette, LA to Chicago from various bus operators like Greyhound US or FlixBus for the next days.

today

$112

tomorrow

$101

Thursday

$109

Friday

Saturday

Sunday

$109

Monday

$111

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	27h 40m	9:35 AM	Lafayette, LA	Bus Stop	1:15 PM	Chicago	95th Red Line Station		Economy	$112	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/3/2026 9:35:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/4/2026 1:15:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 27h 40m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	33h 5m	2:00 AM	Lafayette, LA	Bus Stop	11:05 AM	Chicago	95th Red Line Station	Economy	$101	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/4/2026 2:00:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/5/2026 11:05:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 33h 5m
Greyhound US	27h 40m	9:35 AM	Lafayette, LA	Bus Stop	1:15 PM	Chicago	95th Red Line Station	Economy	$101	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/4/2026 9:35:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/5/2026 1:15:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 27h 40m
Greyhound US	31h 45m	9:25 PM	Lafayette, LA	Bus Stop	5:10 AM	Chicago	95th Red Line Station	Economy	$101	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/4/2026 9:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/6/2026 5:10:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 31h 45m
FlixBus	40h 20m	12:50 PM	Lafayette, LA	TA Travel Center	5:10 AM	Chicago	95th Red Line Station	Economy	$101	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 11/4/2026 12:50:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/6/2026 5:10:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 40h 20m
FlixBus	39h 30m	12:50 PM	Lafayette, LA	TA Travel Center	4:20 AM	Chicago	Downtown Bus Station	Economy	$119	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 11/4/2026 12:50:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/6/2026 4:20:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 39h 30m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	33h 5m	2:00 AM	Lafayette, LA	Bus Stop	11:05 AM	Chicago	95th Red Line Station	Economy	$109	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/5/2026 2:00:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/6/2026 11:05:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 33h 5m
Greyhound US	30h 5m	5:25 PM	Lafayette, LA	Bus Stop	11:30 PM	Chicago	95th Red Line Station	Economy	$109	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/5/2026 5:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/6/2026 11:30:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 30h 5m
FlixBus	26h 0m	9:30 PM	Lafayette, LA	TA Travel Center	11:30 PM	Chicago	95th Red Line Station	Economy	$109	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 11/5/2026 9:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/6/2026 11:30:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 26h 0m
FlixBus	32h 40m	2:25 AM	Lafayette, LA	TA Travel Center	11:05 AM	Chicago	95th Red Line Station	Economy	$110	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 11/5/2026 2:25:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/6/2026 11:05:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 32h 40m
Greyhound US	31h 45m	9:25 PM	Lafayette, LA	Bus Stop	5:10 AM	Chicago	95th Red Line Station	Economy	$111	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/5/2026 9:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/7/2026 5:10:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 31h 45m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	33h 5m	2:00 AM	Lafayette, LA	Bus Stop	11:05 AM	Chicago	95th Red Line Station	Economy	$109	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/8/2026 2:00:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/9/2026 11:05:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 33h 5m
Greyhound US	30h 5m	5:25 PM	Lafayette, LA	Bus Stop	11:30 PM	Chicago	95th Red Line Station	Economy	$110	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/8/2026 5:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/9/2026 11:30:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 30h 5m
FlixBus	32h 40m	2:25 AM	Lafayette, LA	TA Travel Center	11:05 AM	Chicago	95th Red Line Station	Economy	$110	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 11/8/2026 2:25:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/9/2026 11:05:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 32h 40m
FlixBus	26h 0m	9:30 PM	Lafayette, LA	TA Travel Center	11:30 PM	Chicago	95th Red Line Station	Economy	$111	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 11/8/2026 9:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/9/2026 11:30:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 26h 0m
Greyhound US	31h 45m	9:25 PM	Lafayette, LA	Bus Stop	5:10 AM	Chicago	95th Red Line Station	Economy	$112	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/8/2026 9:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/10/2026 5:10:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 31h 45m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	33h 5m	2:00 AM	Lafayette, LA	Bus Stop	11:05 AM	Chicago	95th Red Line Station	Economy	$111	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/9/2026 2:00:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/10/2026 11:05:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 33h 5m
Greyhound US	30h 5m	5:25 PM	Lafayette, LA	Bus Stop	11:30 PM	Chicago	95th Red Line Station	Economy	$111	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/9/2026 5:25:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/10/2026 11:30:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 30h 5m
FlixBus	32h 40m	2:25 AM	Lafayette, LA	TA Travel Center	11:05 AM	Chicago	95th Red Line Station	Economy	$111	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 11/9/2026 2:25:00 AM to 95th Red Line Station, Chicago (USA) arriving at 11/10/2026 11:05:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 32h 40m
FlixBus	26h 0m	9:30 PM	Lafayette, LA	TA Travel Center	11:30 PM	Chicago	95th Red Line Station	Economy	$111	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 11/9/2026 9:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 11/10/2026 11:30:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 26h 0m
Greyhound US	30h 55m	9:25 PM	Lafayette, LA	Bus Stop	4:20 AM	Chicago	Downtown Bus Station	Economy	$120	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 11/9/2026 9:25:00 PM to Downtown Bus Station, Chicago (USA) arriving at 11/11/2026 4:20:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 30h 55m

Best Price Offer: The price for the cheapest bus from Lafayette, LA to Chicago is $101 on 11/11/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Lafayette, LA and Chicago

See here how frequent the connections between Lafayette, LA and Chicago are, during different times and days of the week.

Thursday is the busiest day, with more than 34 daily buses from Lafayette, LA to Chicago. Tuesday has instead the fewest connections, with only 1 daily coaches between Lafayette, LA and Chicago.

The busiest time of the day is the Evening, with 27 buses from Lafayette, LA to Chicago, while Afternoon sees the fewest connections between Lafayette, LA and Chicago, with 11 offers.

Facts about the bus from Lafayette, LA to Chicago

Compare all providers like Greyhound US and FlixBus that travel 16 times every day by bus from Lafayette, LA to Chicago in one click! Book your bus ticket from Lafayette, LA to Chicago starting from $101!

Cheapest Bus	$101
Fastest Bus	23h 5m
Earliest Bus	9:35 AM
Latest Bus	10:35 PM
Daily Bus Routes	16 Ø
Distance	841.4 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Lafayette, LA to Chicago

Every day, 16 buses from 2 bus companies leave Lafayette, LA for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 11/03/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/01

Monday 11/02

Tuesday 11/03

$104

Wednesday 11/04

$121

Thursday 11/05

$109

Friday 11/06

Saturday 11/07

Sunday 11/08

$109

Monday 11/09

$120

Tuesday 11/10

$120

Wednesday 11/11

$101

Thursday 11/12

$108

Friday 11/13

Saturday 11/14

$117

Sunday 11/15

$114

Monday 11/16

$113

Tuesday 11/17

$119

Wednesday 11/18

$124

Thursday 11/19

$152

Friday 11/20

$139

Saturday 11/21

Sunday 11/22

Monday 11/23

$147

Tuesday 11/24

Wednesday 11/25

$137

Thursday 11/26

$116

Friday 11/27

$133

Saturday 11/28

The cheapest time to travel from Lafayette, LA to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Lafayette, LA to Chicago, for the next 30 days.

With a price starting from $101, Wednesday is the cheapest day for a bus from Lafayette, LA to Chicago. Monday instead is the most expensive day with prices starting from $111.

Afternoon is the cheapest day time for bus tickets from Lafayette, LA to Chicago, with $101. Morning is the most expensive time of the day with prices starting from $101.

How to save money travelling from Lafayette, LA to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lafayette, LA to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lafayette, LA to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lafayette, LA to Chicago are also emptier.

All bus stations and stops in Lafayette, LA and Chicago

In the map below, you can see where to find all bus stations in Lafayette, LA and Chicago.

Bus Stop

Lee Ave 100

TA Travel Center

N University Ave 1701

Cameron Street & Alley Five Bus Stop

Cameron St 2405

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Lafayette, LA to Chicago

Want to know which seat classes are available on the buses from Lafayette, LA to Chicago? Or which bus companies serve the route Lafayette, LA to Chicago? Below you will find answers to your questions.

FAQs about the Lafayette, LA to Chicago bus

How much does a Lafayette, LA Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $101 and takes 31h 45m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Lafayette, LA to Chicago?

This route is offered by 2 companies with a range of ticket prices between $101 and $151. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Lafayette, LA to Chicago each day?

Every day, the Lafayette, LA to Chicago bus route is served by approximately 16 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lafayette, LA to Chicago take?

The fastest bus from Lafayette, LA to Chicago is offered by FlixBus and takes 23h 5m. Bus tickets for this connection cost $130. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lafayette, LA to Chicago?

The earliest bus arriving in Chicago from Lafayette, LA starts at 9:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lafayette, LA to Chicago?

The latest bus trip departing from Lafayette, LA for Chicago starts at 10:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lafayette, LA Chicago route?

When traveling by bus from Lafayette, LA to Chicago, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lafayette, LA and Chicago?

You can check all the direct connections between Lafayette, LA and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Lafayette, LA to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lafayette, LA Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lafayette, LA Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lafayette, LA to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Lafayette, LA to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 16 daily trips between Lafayette, LA and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Lafayette, LA to Chicago?

Prices and availability for 16 trips between Lafayette, LA and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Lafayette, LA to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lafayette, LA and to Chicago

Here’s an overview of the most popular bus routes to Lafayette, LA and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!