Bus Lafayette, LA to Chicago: Compare prices and save money

Compare all timetables for the bus from Lafayette, LA to Chicago

Here is a selection of the cheapest bus trips from the schedule from Lafayette, LA to Chicago from various bus operators like Greyhound US or FlixBus for the next days.

today

$150

tomorrow

Sunday

Monday

$110

Tuesday

Wednesday

$168

Thursday

$148

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	30h 50m	9:20 PM	Lafayette, LA	Bus Stop	4:10 AM	Chicago	Downtown Bus Station	Economy	$150	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/5/2025 9:20:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/7/2025 4:10:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 30h 50m
Greyhound US	28h 40m	5:35 PM	Lafayette, LA	Bus Stop	10:15 PM	Chicago	Downtown Bus Station	Economy	$151	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/5/2025 5:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 10:15:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 28h 40m
Greyhound US	29h 40m	9:35 AM	Lafayette, LA	Bus Stop	3:15 PM	Chicago	Downtown Bus Station	Economy	$152	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/5/2025 9:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 3:15:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 29h 40m
FlixBus	25h 25m	8:50 PM	Lafayette, LA	TA Travel Center	10:15 PM	Chicago	Downtown Bus Station	Economy	$152	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 12/5/2025 8:50:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/6/2025 10:15:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 25h 25m
FlixBus	35h 40m	2:30 AM	Lafayette, LA	TA Travel Center	2:10 PM	Chicago	Union Station	Economy	$153	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 12/5/2025 2:30:00 AM to Union Station, Chicago (USA) arriving at 12/6/2025 2:10:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 35h 40m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 15m	5:35 PM	Lafayette, LA	Bus Stop	9:50 PM	Chicago	95th Red Line Station	Economy	$110	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/8/2025 5:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 9:50:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 28h 15m
FlixBus	25h 0m	8:50 PM	Lafayette, LA	TA Travel Center	9:50 PM	Chicago	95th Red Line Station	Economy	$110	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 12/8/2025 8:50:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 9:50:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 25h 0m
FlixBus	32h 35m	2:30 AM	Lafayette, LA	TA Travel Center	11:05 AM	Chicago	95th Red Line Station	Economy	$111	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 12/8/2025 2:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 11:05:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 32h 35m
Greyhound US	31h 50m	2:00 AM	Lafayette, LA	Bus Stop	9:50 AM	Chicago	95th Red Line Station	Economy	$112	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/8/2025 2:00:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 9:50:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 31h 50m
Greyhound US	33h 0m	9:35 AM	Lafayette, LA	Bus Stop	6:35 PM	Chicago	95th Red Line Station	Economy	$112	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/8/2025 9:35:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 6:35:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 33h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	35h 20m	12:50 PM	Lafayette, LA	TA Travel Center	12:10 AM	Chicago	Downtown Bus Station	Economy	$168	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 12/10/2025 12:50:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/12/2025 12:10:00 AM. 50 Economy ticket for $168 per person are available. Travel duration is 35h 20m
Greyhound US	30h 50m	9:20 PM	Lafayette, LA	Bus Stop	4:10 AM	Chicago	Downtown Bus Station	Economy	$169	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/10/2025 9:20:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/12/2025 4:10:00 AM. 50 Economy ticket for $169 per person are available. Travel duration is 30h 50m
Greyhound US	30h 0m	2:00 AM	Lafayette, LA	Bus Stop	8:00 AM	Chicago	Canal & Van Buren	Economy	$170	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/10/2025 2:00:00 AM to Canal & Van Buren, Chicago (USA) arriving at 12/11/2025 8:00:00 AM. 50 Economy ticket for $170 per person are available. Travel duration is 30h 0m
Greyhound US	30h 25m	2:00 AM	Lafayette, LA	Bus Stop	8:25 AM	Chicago	Downtown Bus Station	Economy	$170	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/10/2025 2:00:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/11/2025 8:25:00 AM. 50 Economy ticket for $170 per person are available. Travel duration is 30h 25m
FlixBus	35h 0m	12:50 PM	Lafayette, LA	TA Travel Center	11:50 PM	Chicago	95th Red Line Station	Economy	$181	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 12/10/2025 12:50:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/11/2025 11:50:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 35h 0m

Did you know that if you travel from Lafayette, LA to Chicago via Baton Rouge, you can save more than $25? You can find the corresponding connections below.
- FlixBus
  
  26h 50m
  
  0
  
  2:30 AM
  
  Lafayette, LA
  TA Travel Center
  
  3:25 AM
  
  Baton Rouge
  Park & Ride
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 12/8/2025 2:30:00 AM to Park & Ride, Baton Rouge (USA) arriving at 12/8/2025 3:25:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 0h 55m
- Busbud
  
  23h 15m
  
  0
  
  6:05 AM
  
  Baton Rouge
  Park & Ride
  
  5:20 AM
  
  Chicago
  95th Red Line Station
  
  0
  
  Economy
  
  $130
  
  A Bus from Busbud goes from Park & Ride, Baton Rouge (USA) at 12/8/2025 6:05:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/9/2025 5:20:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 23h 15m
Travel Time is 3h 10m shorter, and you will save $25

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	28h 40m	5:35 PM	Lafayette, LA	Bus Stop	10:15 PM	Chicago	Downtown Bus Station	Economy	$148	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/11/2025 5:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/12/2025 10:15:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 28h 40m
Greyhound US	29h 40m	9:35 AM	Lafayette, LA	Bus Stop	3:15 PM	Chicago	Downtown Bus Station	Economy	$149	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/11/2025 9:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/12/2025 3:15:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 29h 40m
FlixBus	33h 0m	2:30 AM	Lafayette, LA	TA Travel Center	11:30 AM	Chicago	Downtown Bus Station	Economy	$149	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 12/11/2025 2:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/12/2025 11:30:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 33h 0m
FlixBus	25h 25m	8:50 PM	Lafayette, LA	TA Travel Center	10:15 PM	Chicago	Downtown Bus Station	Economy	$149	A Bus from FlixBus goes from TA Travel Center, Lafayette, LA (USA) at 12/11/2025 8:50:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/12/2025 10:15:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 25h 25m
Greyhound US	33h 25m	10:35 PM	Lafayette, LA	Bus Stop	8:00 AM	Chicago	Canal & Van Buren	Economy	$150	A Bus from Greyhound US goes from Bus Stop, Lafayette, LA (USA) at 12/11/2025 10:35:00 PM to Canal & Van Buren, Chicago (USA) arriving at 12/13/2025 8:00:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 33h 25m

Best Price Offer: The price for the cheapest bus from Lafayette, LA to Chicago is $110 on 12/8/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Lafayette, LA and Chicago

See here how frequent the connections between Lafayette, LA and Chicago are, during different times and days of the week.

Thursday is the busiest day, with more than 35 daily buses from Lafayette, LA to Chicago. Friday has instead the fewest connections, with only 18 daily coaches between Lafayette, LA and Chicago.

The busiest time of the day is the Evening, with 44 buses from Lafayette, LA to Chicago, while Morning sees the fewest connections between Lafayette, LA and Chicago, with 16 offers.

Facts about the bus from Lafayette, LA to Chicago

Compare all providers like Greyhound US and FlixBus that travel 27 times every day by bus from Lafayette, LA to Chicago in one click! Book your bus ticket from Lafayette, LA to Chicago starting from $110!

Cheapest Bus	$110
Fastest Bus	25h 0m
Earliest Bus	2:00 AM
Latest Bus	10:35 PM
Daily Bus Routes	27 Ø
Distance	841.4 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Lafayette, LA to Chicago

Every day, 27 buses from 2 bus companies leave Lafayette, LA for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$150

Saturday 12/06

Sunday 12/07

Monday 12/08

$110

Tuesday 12/09

Wednesday 12/10

$168

Thursday 12/11

$179

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

$139

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Lafayette, LA to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Lafayette, LA to Chicago, for the next 30 days.

With a price starting from $110, Monday is the cheapest day for a bus from Lafayette, LA to Chicago. Wednesday instead is the most expensive day with prices starting from $168.

Evening is the cheapest day time for bus tickets from Lafayette, LA to Chicago, with $110. Morning is the most expensive time of the day with prices starting from $112.

How to save money travelling from Lafayette, LA to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lafayette, LA to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lafayette, LA to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lafayette, LA to Chicago are also emptier.

Beloved bus companies from Lafayette, LA to Chicago

These are the most booked bus companies between Lafayette, LA to Chicago from our users.

FlixBus from Lafayette, LA to Chicago

Here you will find the key facts about the FlixBus bus route Lafayette, LA to Chicago:

Cheapest Price	$110
Fastest Bus	25h 0m
Earliest Bus	2:30 AM
Last Bus	8:50 PM
Daily Connections	9 Ø
Found on	12/3/2025

All bus stations and stops in Lafayette, LA and Chicago

In the map below, you can see where to find all bus stations in Lafayette, LA and Chicago.

Bus Stop

Lee Ave 100

TA Travel Center

N University Ave 1701

Cameron Street & Alley Five Bus Stop

Cameron St 2405

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Lafayette, LA to Chicago

Want to know which seat classes are available on the buses from Lafayette, LA to Chicago? Or which bus companies serve the route Lafayette, LA to Chicago? Below you will find answers to your questions.

FAQs about the Lafayette, LA to Chicago bus

How much does a Lafayette, LA Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $110 and takes 25h 0m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Lafayette, LA to Chicago?

This route is offered by 2 companies with a range of ticket prices between $110 and $204. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Lafayette, LA to Chicago each day?

Every day, the Lafayette, LA to Chicago bus route is served by approximately 27 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lafayette, LA to Chicago take?

The fastest bus from Lafayette, LA to Chicago is offered by FlixBus and takes 25h 0m. Bus tickets for this connection cost $162. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lafayette, LA to Chicago?

The earliest bus arriving in Chicago from Lafayette, LA starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lafayette, LA to Chicago?

The latest bus trip departing from Lafayette, LA for Chicago starts at 10:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lafayette, LA Chicago route?

When traveling by bus from Lafayette, LA to Chicago, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lafayette, LA and Chicago?

You can check all the direct connections between Lafayette, LA and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Lafayette, LA to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lafayette, LA Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lafayette, LA Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lafayette, LA to Chicago on your planned travel date.

Available seat classes which are offered on the bus route Lafayette, LA to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lafayette, LA and to Chicago

Here’s an overview of the most popular bus routes to Lafayette, LA and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!