Bus Louisville, KY to Jacksonville, FL: Compare prices and save money

Compare all timetables for the bus from Louisville, KY to Jacksonville, FL

Here is a selection of the cheapest bus trips from the schedule from Louisville, KY to Jacksonville, FL from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

Sunday

Monday

Tuesday

Wednesday

Thursday

$131

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	15h 30m	10:05 PM	Louisville, KY	Greyhound Bus Station	1:35 PM	Jacksonville, FL	Amtrak Train Station	Economy	$131	A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 12/11/2025 10:05:00 PM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/12/2025 1:35:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 15h 30m
FlixBus	18h 20m	1:35 AM	Louisville, KY	Greyhound Bus Station	7:55 PM	Jacksonville, FL	Amtrak Train Station	Economy	$132	A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 12/11/2025 1:35:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/11/2025 7:55:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 18h 20m
Greyhound US	16h 40m	2:20 PM	Louisville, KY	Greyhound Bus Station	7:00 AM	Jacksonville, FL	Amtrak Train Station	Economy	$132	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 12/11/2025 2:20:00 PM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/12/2025 7:00:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 16h 40m
Greyhound US	21h 0m	10:55 PM	Louisville, KY	Greyhound Bus Station	7:55 PM	Jacksonville, FL	Amtrak Train Station	Economy	$132	A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 12/11/2025 10:55:00 PM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/12/2025 7:55:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 21h 0m

Did you know that if you travel from Louisville, KY to Jacksonville, FL via Atlanta, GA, you can save more than $30? You can find the corresponding connections below.
- FlixBus
  
  18h 10m
  
  0
  
  1:35 AM
  
  Louisville, KY
  Greyhound Bus Station
  
  9:25 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $60
  
  A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 12/13/2025 1:35:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 12/13/2025 9:25:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 7h 50m
- Busbud
  
  9h 5m
  
  0
  
  10:40 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  7:45 PM
  
  Jacksonville, FL
  Downtown Bus Stop
  
  0
  
  Economy
  
  $41
  
  A Bus from Busbud goes from Garnett Transit Station, Atlanta, GA (USA) at 12/13/2025 10:40:00 AM to Downtown Bus Stop, Jacksonville, FL (USA) arriving at 12/13/2025 7:45:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 9h 5m
Travel time is 2h 40m longer, but you will save $30

Best Price Offer: The price for the cheapest bus from Louisville, KY to Jacksonville, FL is $129 on 12/13/2025. Flexible travelers save on ticket prices.

Facts about the bus from Louisville, KY to Jacksonville, FL

Compare all providers like FlixBus and Greyhound US that travel 4 times every day by bus from Louisville, KY to Jacksonville, FL in one click! Book your bus ticket from Louisville, KY to Jacksonville, FL starting from $129!

Cheapest Bus	$129
Fastest Bus	15h 30m
Earliest Bus	1:35 AM
Latest Bus	10:55 PM
Daily Bus Routes	4 Ø
Distance	595.4 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Louisville, KY to Jacksonville, FL

Every day, 4 buses from 2 bus companies leave Louisville, KY for Jacksonville, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

Saturday 12/06

Sunday 12/07

Monday 12/08

Tuesday 12/09

Wednesday 12/10

Thursday 12/11

$131

Friday 12/12

Saturday 12/13

$129

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

How to save money travelling from Louisville, KY to Jacksonville, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Louisville, KY to Jacksonville, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Louisville, KY to Jacksonville, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Louisville, KY to Jacksonville, FL are also emptier.

All bus stations and stops in Louisville, KY and Jacksonville, FL

In the map below, you can see where to find all bus stations in Louisville, KY and Jacksonville, FL.

Greyhound Bus Station

W Muhammad Ali Blvd 720

Convention Center

S 3rd St 300

BP Gas Station

Newburg Rd 3301

W Muhammad Ali Blvd

East Broadway, under the I-65 overpass between S 1st Street and S Brook Street

International Airport

Downtown Bus Stop

West Forsyth Street 1111

Central Bus Station

Old St. Augustine Rd

Old St. Augustine Rd 10584-13

Beaver St. & Ocean St. Bus Stop

Friendship Fountain

Service and Comfort on the bus from Louisville, KY to Jacksonville, FL

Want to know which seat classes are available on the buses from Louisville, KY to Jacksonville, FL? Or which bus companies serve the route Louisville, KY to Jacksonville, FL? Below you will find answers to your questions.

FAQs about the Louisville, KY to Jacksonville, FL bus

How much does a Louisville, KY Jacksonville, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $129 and takes 15h 30m to reach Jacksonville, FL. Compare offers to save money!

How much could I save by comparing buses from Louisville, KY to Jacksonville, FL?

This route is offered by 2 companies with a range of ticket prices between $129 and $132. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Jacksonville, FL.

On average, how many connections are available from Louisville, KY to Jacksonville, FL each day?

Every day, the Louisville, KY to Jacksonville, FL bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Louisville, KY to Jacksonville, FL take?

The fastest bus from Louisville, KY to Jacksonville, FL is offered by FlixBus and takes 15h 30m. Bus tickets for this connection cost $131. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Louisville, KY to Jacksonville, FL?

The earliest bus arriving in Jacksonville, FL from Louisville, KY starts at 1:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Louisville, KY to Jacksonville, FL?

The latest bus trip departing from Louisville, KY for Jacksonville, FL starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Louisville, KY Jacksonville, FL route?

When traveling by bus from Louisville, KY to Jacksonville, FL, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Louisville, KY and Jacksonville, FL?

You can check all the direct connections between Louisville, KY and Jacksonville, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Louisville, KY to Jacksonville, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Louisville, KY Jacksonville, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Louisville, KY Jacksonville, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Louisville, KY to Jacksonville, FL on your planned travel date.

Available seat classes which are offered on the bus route Louisville, KY to Jacksonville, FL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Louisville, KY and to Jacksonville, FL

Here’s an overview of the most popular bus routes to Louisville, KY and to Jacksonville, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!