Bus Luxembourg City to Rome - Compare all Companies

Compare all timetables for the bus from Luxembourg City to Rome

Here is a selection of the cheapest bus trips from the schedule from Luxembourg City to Rome from various bus operators like FlixBus for the next days.

today

$170

tomorrow

$185

Monday

$145

Tuesday

$138

Wednesday

$133

Thursday

$149

Friday

$152

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 0m	11:25 PM	Luxembourg City	P+R Bouillon	9:25 PM	Rome	Tiburtina Bus Station	Economy	$170	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/20/2025 11:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 9:25:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 22h 0m
FlixBus	23h 40m	1:40 PM	Luxembourg City	P+R Bouillon	1:20 PM	Rome	Tiburtina Bus Station	Economy	$176	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/20/2025 1:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 1:20:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 23h 40m
FlixBus	25h 25m	1:40 PM	Luxembourg City	P+R Bouillon	3:05 PM	Rome	Anagnina Bus Station	Economy	$177	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/20/2025 1:40:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/21/2025 3:05:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 25h 25m
FlixBus	19h 30m	9:00 PM	Luxembourg City	P+R Bouillon	4:30 PM	Rome	Tiburtina Bus Station	Economy	$178	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/20/2025 9:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 4:30:00 PM. 50 Economy ticket for $178 per person are available. Travel duration is 19h 30m
FlixBus	21h 5m	9:00 PM	Luxembourg City	P+R Bouillon	6:05 PM	Rome	Anagnina Bus Station	Economy	$198	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/20/2025 9:00:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/21/2025 6:05:00 PM. 50 Economy ticket for $198 per person are available. Travel duration is 21h 5m

Did you know that if you travel from Luxembourg City to Rome via Zurich, you can save more than $48? You can find the corresponding connections below.
- FlixBus
  
  29h 5m
  
  0
  
  3:00 AM
  
  Luxembourg City
  P+R Bouillon
  
  9:40 AM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $55
  
  A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/22/2025 3:00:00 AM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/22/2025 9:40:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 6h 40m
- INFOBUS
  
  14h 45m
  
  0
  
  5:20 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  8:05 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $67
  
  A Bus from INFOBUS goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/22/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 8:05:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 14h 45m
Travel time is 9h 35m longer, but you will save $48

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	25h 15m	4:45 PM	Luxembourg City	P+R Bouillon	6:00 PM	Rome	Anagnina Bus Station	Economy	$185	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/21/2025 4:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/22/2025 6:00:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 25h 15m
FlixBus	24h 15m	5:50 AM	Luxembourg City	P+R Bouillon	6:05 AM	Rome	Anagnina Bus Station	Economy	$194	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/21/2025 5:50:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/22/2025 6:05:00 AM. 50 Economy ticket for $194 per person are available. Travel duration is 24h 15m
FlixBus	22h 0m	11:25 PM	Luxembourg City	P+R Bouillon	9:25 PM	Rome	Tiburtina Bus Station	Economy	$196	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/21/2025 11:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 9:25:00 PM. 50 Economy ticket for $196 per person are available. Travel duration is 22h 0m
FlixBus	23h 45m	5:50 AM	Luxembourg City	P+R Bouillon	5:35 AM	Rome	Tiburtina Bus Station	Economy	$199	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/21/2025 5:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 5:35:00 AM. 50 Economy ticket for $199 per person are available. Travel duration is 23h 45m
FlixBus	23h 5m	10:25 AM	Luxembourg City	P+R Bouillon	9:30 AM	Rome	Tiburtina Bus Station	Economy	$201	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/21/2025 10:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/22/2025 9:30:00 AM. 50 Economy ticket for $201 per person are available. Travel duration is 23h 5m

Did you know that if you travel from Luxembourg City to Rome via Zurich, you can save more than $66? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  29h 40m
  
  0
  
  2:25 AM
  
  Luxembourg City
  Central Bus Station
  
  8:55 AM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $53
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Luxembourg City (Luxembourg) at 12/22/2025 2:25:00 AM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/22/2025 8:55:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 6h 30m
- INFOBUS
  
  14h 45m
  
  0
  
  5:20 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  8:05 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $67
  
  A Bus from INFOBUS goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/22/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 8:05:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 14h 45m
Travel time is 7h 40m longer, but you will save $66

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	25h 15m	4:45 PM	Luxembourg City	P+R Bouillon	6:00 PM	Rome	Anagnina Bus Station	Economy	$145	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/22/2025 4:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/23/2025 6:00:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 25h 15m
FlixBus	25h 25m	1:40 PM	Luxembourg City	P+R Bouillon	3:05 PM	Rome	Anagnina Bus Station	Economy	$153	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/22/2025 1:40:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/23/2025 3:05:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 25h 25m
FlixBus	23h 40m	1:40 PM	Luxembourg City	P+R Bouillon	1:20 PM	Rome	Tiburtina Bus Station	Economy	$156	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/22/2025 1:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 1:20:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 23h 40m
FlixBus	23h 5m	10:25 AM	Luxembourg City	P+R Bouillon	9:30 AM	Rome	Tiburtina Bus Station	Economy	$157	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/22/2025 10:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 9:30:00 AM. 50 Economy ticket for $157 per person are available. Travel duration is 23h 5m
FlixBus	22h 0m	11:25 PM	Luxembourg City	P+R Bouillon	9:25 PM	Rome	Tiburtina Bus Station	Economy	$162	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/22/2025 11:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 9:25:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 22h 0m

Did you know that if you travel from Luxembourg City to Rome via Zurich, you can save more than $49? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  29h 40m
  
  0
  
  2:25 AM
  
  Luxembourg City
  Central Bus Station
  
  8:55 AM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $32
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Luxembourg City (Luxembourg) at 12/24/2025 2:25:00 AM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/24/2025 8:55:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 30m
- Distribusion
  
  14h 45m
  
  0
  
  5:20 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  8:05 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $64
  
  A Bus from Distribusion goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/24/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 8:05:00 AM. 50 Premium Economy ticket for $64 per person are available. Travel duration is 14h 45m
Travel time is 7h 40m longer, but you will save $49

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 40m	1:40 PM	Luxembourg City	P+R Bouillon	1:20 PM	Rome	Tiburtina Bus Station	Economy	$138	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/23/2025 1:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/24/2025 1:20:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 23h 40m
FlixBus	25h 25m	1:40 PM	Luxembourg City	P+R Bouillon	3:05 PM	Rome	Anagnina Bus Station	Economy	$142	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/23/2025 1:40:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/24/2025 3:05:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 25h 25m
FlixBus	19h 30m	9:00 PM	Luxembourg City	P+R Bouillon	4:30 PM	Rome	Tiburtina Bus Station	Economy	$174	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/23/2025 9:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/24/2025 4:30:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 19h 30m
FlixBus	23h 5m	10:25 AM	Luxembourg City	P+R Bouillon	9:30 AM	Rome	Tiburtina Bus Station	Economy	$177	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/23/2025 10:25:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/24/2025 9:30:00 AM. 50 Economy ticket for $177 per person are available. Travel duration is 23h 5m
FlixBus	24h 20m	5:50 AM	Luxembourg City	P+R Bouillon	6:10 AM	Rome	Tiburtina Bus Station	Economy	$184	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/23/2025 5:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/24/2025 6:10:00 AM. 50 Economy ticket for $184 per person are available. Travel duration is 24h 20m

Did you know that if you travel from Luxembourg City to Rome via Zurich, you can save more than $16? You can find the corresponding connections below.
- FlixBus
  
  29h 5m
  
  0
  
  3:00 AM
  
  Luxembourg City
  P+R Bouillon
  
  9:40 AM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $55
  
  A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/22/2025 3:00:00 AM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/22/2025 9:40:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 6h 40m
- INFOBUS
  
  14h 45m
  
  0
  
  5:20 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  8:05 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $67
  
  A Bus from INFOBUS goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/22/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 8:05:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 14h 45m
Travel time is 9h 35m longer, but you will save $16

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	28h 15m	3:35 AM	Luxembourg City	P+R Bouillon	7:50 AM	Rome	Tiburtina Bus Station	Economy	$133	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/24/2025 3:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 7:50:00 AM. 50 Economy ticket for $133 per person are available. Travel duration is 28h 15m
FlixBus	23h 40m	1:40 PM	Luxembourg City	P+R Bouillon	1:20 PM	Rome	Tiburtina Bus Station	Economy	$133	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/24/2025 1:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 1:20:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 23h 40m
FlixBus	21h 35m	9:00 PM	Luxembourg City	P+R Bouillon	6:35 PM	Rome	Tiburtina Bus Station	Economy	$157	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/24/2025 9:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 6:35:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 21h 35m
FlixBus	23h 10m	11:25 PM	Luxembourg City	P+R Bouillon	10:35 PM	Rome	Tiburtina Bus Station	Economy	$167	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/24/2025 11:25:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 10:35:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 23h 10m
FlixBus	23h 5m	10:55 AM	Luxembourg City	P+R Bouillon	10:00 AM	Rome	Tiburtina Bus Station	Economy	$177	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/24/2025 10:55:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 10:00:00 AM. 50 Economy ticket for $177 per person are available. Travel duration is 23h 5m

Did you know that if you travel from Luxembourg City to Rome via Zurich, you can save more than $37? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  29h 40m
  
  0
  
  2:25 AM
  
  Luxembourg City
  Central Bus Station
  
  8:55 AM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $32
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Luxembourg City (Luxembourg) at 12/24/2025 2:25:00 AM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/24/2025 8:55:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 30m
- Distribusion
  
  14h 45m
  
  0
  
  5:20 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  8:05 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $64
  
  A Bus from Distribusion goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/24/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 8:05:00 AM. 50 Premium Economy ticket for $64 per person are available. Travel duration is 14h 45m
Travel time is 8h 5m longer, but you will save $37

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	29h 5m	1:00 AM	Luxembourg City	Central Bus Station	6:05 AM	Rome	Anagnina Bus Station	Economy	$149	A Bus from FlixBus goes from Central Bus Station, Luxembourg City (Luxembourg) at 12/25/2025 1:00:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/26/2025 6:05:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 29h 5m
FlixBus	25h 20m	4:45 PM	Luxembourg City	P+R Bouillon	6:05 PM	Rome	Anagnina Bus Station	Economy	$149	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/25/2025 4:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/26/2025 6:05:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 25h 20m
FlixBus	28h 15m	3:35 AM	Luxembourg City	P+R Bouillon	7:50 AM	Rome	Tiburtina Bus Station	Economy	$154	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/25/2025 3:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/26/2025 7:50:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 28h 15m
FlixBus	28h 20m	1:40 PM	Luxembourg City	P+R Bouillon	6:00 PM	Rome	Anagnina Bus Station	Economy	$154	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/25/2025 1:40:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/26/2025 6:00:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 28h 20m
FlixBus	23h 40m	1:40 PM	Luxembourg City	P+R Bouillon	1:20 PM	Rome	Tiburtina Bus Station	Economy	$160	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/25/2025 1:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/26/2025 1:20:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 23h 40m

Did you know that if you travel from Luxembourg City to Rome via Zurich, you can save more than $53? You can find the corresponding connections below.
- BlaBlaCar Bus
  
  29h 40m
  
  0
  
  2:25 AM
  
  Luxembourg City
  Central Bus Station
  
  8:55 AM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $32
  
  A Bus from BlaBlaCar Bus goes from Central Bus Station, Luxembourg City (Luxembourg) at 12/24/2025 2:25:00 AM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/24/2025 8:55:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 6h 30m
- Distribusion
  
  14h 45m
  
  0
  
  5:20 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  8:05 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $64
  
  A Bus from Distribusion goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/24/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 8:05:00 AM. 50 Premium Economy ticket for $64 per person are available. Travel duration is 14h 45m
Travel time is 6h 0m longer, but you will save $53

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	25h 25m	1:40 PM	Luxembourg City	P+R Bouillon	3:05 PM	Rome	Anagnina Bus Station	Economy	$152	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/26/2025 1:40:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/27/2025 3:05:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 25h 25m
FlixBus	19h 30m	9:00 PM	Luxembourg City	P+R Bouillon	4:30 PM	Rome	Tiburtina Bus Station	Economy	$153	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/26/2025 9:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/27/2025 4:30:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 19h 30m
FlixBus	23h 40m	1:40 PM	Luxembourg City	P+R Bouillon	1:20 PM	Rome	Tiburtina Bus Station	Economy	$160	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/26/2025 1:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/27/2025 1:20:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 23h 40m
FlixBus	25h 15m	4:45 PM	Luxembourg City	P+R Bouillon	6:00 PM	Rome	Anagnina Bus Station	Economy	$163	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/26/2025 4:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/27/2025 6:00:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 25h 15m
FlixBus	28h 15m	3:35 AM	Luxembourg City	P+R Bouillon	7:50 AM	Rome	Tiburtina Bus Station	Economy	$166	A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/26/2025 3:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/27/2025 7:50:00 AM. 50 Economy ticket for $166 per person are available. Travel duration is 28h 15m

Did you know that if you travel from Luxembourg City to Rome via Zurich, you can save more than $30? You can find the corresponding connections below.
- FlixBus
  
  29h 5m
  
  0
  
  3:00 AM
  
  Luxembourg City
  P+R Bouillon
  
  9:40 AM
  
  Zurich
  Central Bus Station Sihlquai
  
  0
  
  Economy
  
  $55
  
  A Bus from FlixBus goes from P+R Bouillon, Luxembourg City (Luxembourg) at 12/22/2025 3:00:00 AM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/22/2025 9:40:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 6h 40m
- INFOBUS
  
  14h 45m
  
  0
  
  5:20 PM
  
  Zurich
  Central Bus Station Sihlquai
  
  8:05 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $67
  
  A Bus from INFOBUS goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/22/2025 5:20:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/23/2025 8:05:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 14h 45m
Travel time is 9h 35m longer, but you will save $30

Best Price Offer: The price for the cheapest bus from Luxembourg City to Rome is $64 on 1/9/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Luxembourg City and Rome

See here how frequent the connections between Luxembourg City and Rome are, during different times and days of the week.

Sunday is the busiest day, with more than 13 daily buses from Luxembourg City to Rome. Wednesday has instead the fewest connections, with only 7 daily coaches between Luxembourg City and Rome.

The busiest time of the day is the Evening, with 19 buses from Luxembourg City to Rome, while Night sees the fewest connections between Luxembourg City and Rome, with 14 offers.

Facts about the bus from Luxembourg City to Rome

Compare all providers like FlixBus that travel 9 times every day by bus from Luxembourg City to Rome in one click! Book your bus ticket from Luxembourg City to Rome starting from $64!

Cheapest Bus	$64
Fastest Bus	19h 30m
Earliest Bus	10:55 AM
Latest Bus	11:25 PM
Daily Bus Routes	9 Ø
Distance	614.5 miles
Bus Companies	FlixBus

Cheapest bus connections from Luxembourg City to Rome

Every day, 9 buses from 1 bus companies leave Luxembourg City for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/20/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

$170

Sunday 12/21

$185

Monday 12/22

$145

Tuesday 12/23

$138

Wednesday 12/24

$133

Thursday 12/25

$149

Friday 12/26

$152

Saturday 12/27

$153

Sunday 12/28

$125

Monday 12/29

$125

Tuesday 12/30

$125

Wednesday 12/31

$131

Thursday 01/01

$153

Friday 01/02

$131

Saturday 01/03

$109

Sunday 01/04

$108

Monday 01/05

$70

Tuesday 01/06

$72

Wednesday 01/07

$68

Thursday 01/08

$66

Friday 01/09

$64

Saturday 01/10

The cheapest time to travel from Luxembourg City to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Luxembourg City to Rome, for the next 30 days.

With a price starting from $50, Monday is the cheapest day for a bus from Luxembourg City to Rome. Friday instead is the most expensive day with prices starting from $64.

Night is the cheapest day time for bus tickets from Luxembourg City to Rome, with $50. Morning is the most expensive time of the day with prices starting from $157.

How to save money travelling from Luxembourg City to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Luxembourg City to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Luxembourg City to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Luxembourg City to Rome are also emptier.

All bus stations and stops in Luxembourg City and Rome

In the map below, you can see where to find all bus stations in Luxembourg City and Rome.

Central Bus Station

Place de la Gare

P+R Bouillon

Rue de Bouillon

Bus Stop

Rue Mercier 2

Limpertsberg

Avenue de la Faïencerie

Gasperich

Rue In Bouler 1

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Service and Comfort on the bus from Luxembourg City to Rome

Want to know which seat classes are available on the buses from Luxembourg City to Rome? Or which bus companies serve the route Luxembourg City to Rome? Below you will find answers to your questions.

FAQs about the Luxembourg City to Rome bus

How much does a Luxembourg City Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $64 and takes 28h 15m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Luxembourg City to Rome?

This route is offered by 1 companies with a range of ticket prices between $64 and $252. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Luxembourg City to Rome each day?

Every day, the Luxembourg City to Rome bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Luxembourg City to Rome take?

The fastest bus from Luxembourg City to Rome is offered by FlixBus and takes 19h 30m. Bus tickets for this connection cost $178. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Luxembourg City to Rome?

The earliest bus arriving in Rome from Luxembourg City starts at 10:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Luxembourg City to Rome?

The latest bus trip departing from Luxembourg City for Rome starts at 11:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Luxembourg City Rome route?

When traveling by bus from Luxembourg City to Rome, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Luxembourg City and Rome?

You can check all the direct connections between Luxembourg City and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Luxembourg City to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Luxembourg City Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Luxembourg City Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Luxembourg City to Rome on your planned travel date.

How does CheckMyBus find the best bus deals from Luxembourg City to Rome?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Luxembourg City and Rome. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Luxembourg City to Rome?

Prices and availability for 9 trips between Luxembourg City and Rome change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Luxembourg City to Rome

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Luxembourg City and to Rome

Here’s an overview of the most popular bus routes to Luxembourg City and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!