Bus Mersin to Istanbul: Compare prices and save money

Compare all timetables for the bus from Mersin to Istanbul

Here is a selection of the cheapest bus trips from the schedule from Mersin to Istanbul from various bus operators like Metro Turizm, FlixBus or Gülnarlılar Mersin Nur Turizm for the next days.

today

$40

tomorrow

$41

Wednesday

$43

Thursday

$43

Friday

$43

Saturday

$41

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Metro Turizm	13h 0m	11:00 PM	Mersin	Yeni Otogar	12:00 PM	Istanbul	Samandira Bus Station	Economy	$40	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 6/22/2026 11:00:00 PM to Samandira Bus Station, Istanbul (Turkey) arriving at 6/23/2026 12:00:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 13h 0m
FlixBus	13h 25m	12:00 PM	Mersin	Yeni Otogar	1:25 AM	Istanbul	Alibeyköy Otogarı	Economy	$42	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/22/2026 12:00:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 6/23/2026 1:25:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 13h 25m
Kamil Koc	13h 45m	12:00 PM	Mersin	Central Station	1:45 AM	Istanbul	Esenler Bus Station	Economy	$42	A Bus from Kamil Koc goes from Central Station, Mersin (Turkey) at 6/22/2026 12:00:00 PM to Esenler Bus Station, Istanbul (Turkey) arriving at 6/23/2026 1:45:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 13h 45m
Villa Seyahat	15h 0m	2:00 AM	Mersin	Central Station	5:00 PM	Istanbul	Alibeyköy Otogarı	Economy	$47	A Bus from Villa Seyahat goes from Central Station, Mersin (Turkey) at 6/22/2026 2:00:00 AM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 6/22/2026 5:00:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 15h 0m
Gülnarlılar Mersin Nur Turizm	16h 0m	10:00 AM	Mersin	Central Station	2:00 AM	Istanbul	Alibeyköy Otogarı	Economy	$47	A Bus from Gülnarlılar Mersin Nur Turizm goes from Central Station, Mersin (Turkey) at 6/22/2026 10:00:00 AM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 6/23/2026 2:00:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 16h 0m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Kamil Koc	13h 45m	12:00 PM	Mersin	Central Station	1:45 AM	Istanbul	Esenler Bus Station	Economy	$41	A Bus from Kamil Koc goes from Central Station, Mersin (Turkey) at 6/23/2026 12:00:00 PM to Esenler Bus Station, Istanbul (Turkey) arriving at 6/24/2026 1:45:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 13h 45m
Kamil Koc	15h 5m	5:30 PM	Mersin	Central Station	8:35 AM	Istanbul	Esenler Bus Station	Economy	$41	A Bus from Kamil Koc goes from Central Station, Mersin (Turkey) at 6/23/2026 5:30:00 PM to Esenler Bus Station, Istanbul (Turkey) arriving at 6/24/2026 8:35:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 15h 5m
FlixBus	12h 0m	12:00 PM	Mersin	Yeni Otogar	12:00 AM	Istanbul	Dudullu Bus Station	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/23/2026 12:00:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 6/24/2026 12:00:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 12h 0m
FlixBus	13h 35m	5:30 PM	Mersin	Yeni Otogar	7:05 AM	Istanbul	Dudullu Bus Station	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/23/2026 5:30:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 6/24/2026 7:05:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 13h 35m
Metro Turizm	11h 0m	7:30 PM	Mersin	Yeni Otogar	6:30 AM	Istanbul	Samandira Bus Station	Economy	$54	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 6/23/2026 7:30:00 PM to Samandira Bus Station, Istanbul (Turkey) arriving at 6/24/2026 6:30:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 45m	12:00 PM	Mersin	Yeni Otogar	1:45 AM	Istanbul	Otogar Bus Station	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/24/2026 12:00:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 6/25/2026 1:45:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 13h 45m
FlixBus	14h 45m	11:00 PM	Mersin	Yeni Otogar	1:45 PM	Istanbul	Otogar Bus Station	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/24/2026 11:00:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 6/25/2026 1:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 14h 45m
FlixBus	13h 25m	12:00 PM	Mersin	Yeni Otogar	1:25 AM	Istanbul	Alibeyköy Otogarı	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/24/2026 12:00:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 6/25/2026 1:25:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 13h 25m
Metro Turizm	12h 20m	7:30 PM	Mersin	Yeni Otogar	7:50 AM	Istanbul	Otogar Bus Station	Economy	$54	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 6/24/2026 7:30:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 6/25/2026 7:50:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 12h 20m
Metro Turizm	14h 50m	8:00 PM	Mersin	Yeni Otogar	10:50 AM	Istanbul	Otogar Bus Station	Economy	$54	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 6/24/2026 8:00:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 6/25/2026 10:50:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 14h 50m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 0m	12:00 PM	Mersin	Yeni Otogar	12:00 AM	Istanbul	Dudullu Bus Station	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/25/2026 12:00:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 6/26/2026 12:00:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 12h 0m
FlixBus	13h 35m	5:30 PM	Mersin	Yeni Otogar	7:05 AM	Istanbul	Dudullu Bus Station	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/25/2026 5:30:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 6/26/2026 7:05:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 13h 35m
FlixBus	13h 10m	11:00 PM	Mersin	Yeni Otogar	12:10 PM	Istanbul	Dudullu Bus Station	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/25/2026 11:00:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 6/26/2026 12:10:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 13h 10m
Metro Turizm	11h 0m	7:30 PM	Mersin	Yeni Otogar	6:30 AM	Istanbul	Samandira Bus Station	Economy	$54	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 6/25/2026 7:30:00 PM to Samandira Bus Station, Istanbul (Turkey) arriving at 6/26/2026 6:30:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 0m
Metro Turizm	13h 15m	8:00 PM	Mersin	Yeni Otogar	9:15 AM	Istanbul	Samandira Bus Station	Economy	$54	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 6/25/2026 8:00:00 PM to Samandira Bus Station, Istanbul (Turkey) arriving at 6/26/2026 9:15:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 13h 15m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 45m	12:00 PM	Mersin	Yeni Otogar	1:45 AM	Istanbul	Otogar Bus Station	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/26/2026 12:00:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 6/27/2026 1:45:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 13h 45m
FlixBus	14h 45m	11:00 PM	Mersin	Yeni Otogar	1:45 PM	Istanbul	Otogar Bus Station	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/26/2026 11:00:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 6/27/2026 1:45:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 14h 45m
FlixBus	13h 25m	12:00 PM	Mersin	Yeni Otogar	1:25 AM	Istanbul	Alibeyköy Otogarı	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/26/2026 12:00:00 PM to Alibeyköy Otogarı, Istanbul (Turkey) arriving at 6/27/2026 1:25:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 13h 25m
Metro Turizm	12h 20m	7:30 PM	Mersin	Yeni Otogar	7:50 AM	Istanbul	Otogar Bus Station	Economy	$54	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 6/26/2026 7:30:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 6/27/2026 7:50:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 12h 20m
Metro Turizm	14h 50m	8:00 PM	Mersin	Yeni Otogar	10:50 AM	Istanbul	Otogar Bus Station	Economy	$54	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 6/26/2026 8:00:00 PM to Otogar Bus Station, Istanbul (Turkey) arriving at 6/27/2026 10:50:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 14h 50m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Kamil Koc	13h 45m	12:00 PM	Mersin	Central Station	1:45 AM	Istanbul	Esenler Bus Station	Economy	$41	A Bus from Kamil Koc goes from Central Station, Mersin (Turkey) at 6/27/2026 12:00:00 PM to Esenler Bus Station, Istanbul (Turkey) arriving at 6/28/2026 1:45:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 13h 45m
Kamil Koc	15h 5m	5:30 PM	Mersin	Central Station	8:35 AM	Istanbul	Esenler Bus Station	Economy	$41	A Bus from Kamil Koc goes from Central Station, Mersin (Turkey) at 6/27/2026 5:30:00 PM to Esenler Bus Station, Istanbul (Turkey) arriving at 6/28/2026 8:35:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 15h 5m
FlixBus	12h 0m	12:00 PM	Mersin	Yeni Otogar	12:00 AM	Istanbul	Dudullu Bus Station	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/27/2026 12:00:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 6/28/2026 12:00:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 12h 0m
FlixBus	13h 35m	5:30 PM	Mersin	Yeni Otogar	7:05 AM	Istanbul	Dudullu Bus Station	Economy	$43	A Bus from FlixBus goes from Yeni Otogar, Mersin (Turkey) at 6/27/2026 5:30:00 PM to Dudullu Bus Station, Istanbul (Turkey) arriving at 6/28/2026 7:05:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 13h 35m
Metro Turizm	11h 0m	7:30 PM	Mersin	Yeni Otogar	6:30 AM	Istanbul	Samandira Bus Station	Economy	$54	A Bus from Metro Turizm goes from Yeni Otogar, Mersin (Turkey) at 6/27/2026 7:30:00 PM to Samandira Bus Station, Istanbul (Turkey) arriving at 6/28/2026 6:30:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 0m

Best Price Offer: The price for the cheapest bus from Mersin to Istanbul is $37 on 6/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Mersin and Istanbul

See here how frequent the connections between Mersin and Istanbul are, during different times and days of the week.

Monday is the busiest day, with more than 80 daily buses from Mersin to Istanbul. Thursday has instead the fewest connections, with only 5 daily coaches between Mersin and Istanbul.

The busiest time of the day is the Evening, with 69 buses from Mersin to Istanbul, while Night sees the fewest connections between Mersin and Istanbul, with 2 offers.

Facts about the bus from Mersin to Istanbul

Compare all providers like Metro Turizm, FlixBus and Gülnarlılar Mersin Nur Turizm that travel 19 times every day by bus from Mersin to Istanbul in one click! Book your bus ticket from Mersin to Istanbul starting from $37!

Cheapest Bus	$37
Fastest Bus	11h 0m
Earliest Bus	2:00 AM
Latest Bus	11:00 PM
Daily Bus Routes	19 Ø
Distance	420.4 miles
Bus Companies	Metro Turizm, FlixBus, Gülnarlılar Mersin Nur Turizm, Villa Seyahat, Lüks Mersin, Kamil Koc, Mersin Seyahat, İnan Turizm and Özkaymak Turizm

Cheapest bus connections from Mersin to Istanbul

Every day, 19 buses from 9 bus companies leave Mersin for Istanbul: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/21

Monday 06/22

$37

Tuesday 06/23

$41

Wednesday 06/24

$43

Thursday 06/25

$39

Friday 06/26

$39

Saturday 06/27

$39

Sunday 06/28

Monday 06/29

$41

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

$52

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

Friday 07/10

$48

Saturday 07/11

$44

Sunday 07/12

$50

Monday 07/13

$39

Tuesday 07/14

$51

Wednesday 07/15

$39

Thursday 07/16

$50

Friday 07/17

$46

Saturday 07/18

The cheapest time to travel from Mersin to Istanbul

See here on which day and which time of the day you can find the cheapest bus ticket from Mersin to Istanbul, for the next 30 days.

With a price starting from $37, Monday is the cheapest day for a bus from Mersin to Istanbul. Tuesday instead is the most expensive day with prices starting from $41.

Night is the cheapest day time for bus tickets from Mersin to Istanbul, with $37. Morning is the most expensive time of the day with prices starting from $47.

How to save money travelling from Mersin to Istanbul

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mersin to Istanbul in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mersin to Istanbul, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mersin to Istanbul are also emptier.

Beloved bus companies from Mersin to Istanbul

These are the most booked bus companies between Mersin to Istanbul from our users.

Lüks Mersin from Mersin to Istanbul

Here you will find the key facts about the Lüks Mersin bus route Mersin to Istanbul:

Cheapest Price	$47
Fastest Bus	14h 0m
Earliest Bus	4:30 PM
Last Bus	10:30 PM
Daily Connections	12 Ø
Found on	6/21/2026

All bus stations and stops in Mersin and Istanbul

In the map below, you can see where to find all bus stations in Mersin and Istanbul.

Yeni Otogar

Port

Mut

Bus Stop

Menteş

Alibeyköy Otogarı

Güzeltepe, Fatih Sultan Mehmet Blv 18

Dudullu Bus Station

Kible Sokak 38

Esenler Bus Station

Altıntepsi

Otogar Bus Station

Altıntepsi Mahallesi Bayrampasa-Istanbul

Samandira Bus Station

Tuna Cd 4

Service and Comfort on the bus from Mersin to Istanbul

Want to know which seat classes are available on the buses from Mersin to Istanbul? Or which bus companies serve the route Mersin to Istanbul? Below you will find answers to your questions.

FAQs about the Mersin to Istanbul bus

How much does a Mersin Istanbul bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $37 and takes 13h 0m to reach Istanbul. Compare offers to save money!

How much could I save by comparing buses from Mersin to Istanbul?

This route is offered by 9 companies with a range of ticket prices between $37 and $54. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Istanbul.

On average, how many connections are available from Mersin to Istanbul each day?

Every day, the Mersin to Istanbul bus route is served by approximately 19 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mersin to Istanbul take?

The fastest bus from Mersin to Istanbul is offered by Metro Turizm and takes 11h 0m. Bus tickets for this connection cost $54. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mersin to Istanbul?

The earliest bus arriving in Istanbul from Mersin starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mersin to Istanbul?

The latest bus trip departing from Mersin for Istanbul starts at 11:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mersin Istanbul route?

When traveling by bus from Mersin to Istanbul, passengers can travel with Metro Turizm, FlixBus and Gülnarlılar Mersin Nur Turizm. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mersin and Istanbul?

You can check all the direct connections between Mersin and Istanbul by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Metro Turizm, FlixBus and Gülnarlılar Mersin Nur Turizm.

What can I take with me on the Mersin to Istanbul bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mersin Istanbul bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mersin Istanbul bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mersin to Istanbul on your planned travel date.

How does CheckMyBus find the best bus deals from Mersin to Istanbul?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 19 daily trips between Mersin and Istanbul. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mersin to Istanbul?

Prices and availability for 19 trips between Mersin and Istanbul change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mersin to Istanbul

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mersin and to Istanbul

Here’s an overview of the most popular bus routes to Mersin and to Istanbul. Simply click on the connection of your choice, and you will find all the details about your bus route!