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Bus from Mesa, AZ to San Diego from $64

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Compare all timetables for the bus from Mesa, AZ to San Diego

Here is a selection of the cheapest bus trips from the schedule from Mesa, AZ to San Diego from various bus operators like Greyhound US for the next days.
today
tomorrow
from $79
Monday
from $64
Tuesday
from $71
Wednesday
Thursday
from $65
Friday
from $77

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    12h 30m
    0
    1:45 PM
    Mesa, AZ
    Greyhound
    2:15 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $79
  • Greyhound US
    12h 5m
    0
    1:45 PM
    Mesa, AZ
    Greyhound
    1:50 AM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $85
  • Greyhound US
    12h 35m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    8:45 AM
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    $179
  • Greyhound US
    13h 5m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:15 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $180
  • Greyhound US
    13h 55m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $182
  • Did you know that if you travel from Mesa, AZ to San Diego via Los Angeles, you can save more than $8? You can find the corresponding connections below.
    • Busbud
      13h 20m
      0
      8:10 PM
      Mesa, AZ
      Greyhound
      5:50 AM
      Los Angeles
      North Hollywood
      0
      Busbud
      Economy
      $46
      • Waiting Time 0h 15m
    • Busbud
      3h 25m
      0
      6:05 AM
      Los Angeles
      Union Station
      9:30 AM
      San Diego
      Old Town Transit Center
      0
      Busbud
      Economy
      $25
    Travel time is 1h 15m longer, but you will save $8

Cheapest bus trips Monday

Prices are for one way and one person
  • Greyhound US
    14h 50m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    11:00 AM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $64
  • Greyhound US
    14h 30m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    10:40 AM
    San Diego
    Balboa Park
    0
    Greyhound US
    Economy
    $64
  • Greyhound US
    13h 5m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:15 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $65
  • Greyhound US
    13h 20m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $65

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    13h 5m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:15 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $71
  • Greyhound US
    13h 20m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $71
  • Greyhound US
    13h 55m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $73
  • Greyhound US
    13h 20m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $76
  • Greyhound US
    12h 35m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    8:45 AM
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    $76

Cheapest bus trips Thursday

Prices are for one way and one person
  • Greyhound US
    13h 5m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:15 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $65
  • Greyhound US
    13h 20m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $65
  • Greyhound US
    13h 5m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:15 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $67
  • Greyhound US
    13h 20m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $67
  • Greyhound US
    12h 5m
    0
    1:45 PM
    Mesa, AZ
    Greyhound
    1:50 AM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $68

Cheapest bus trips Friday

Prices are for one way and one person
  • Greyhound US
    13h 55m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $77
  • Greyhound US
    12h 30m
    0
    1:45 PM
    Mesa, AZ
    Greyhound
    2:15 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $85

Frequency of bus connections between Mesa, AZ and San Diego

See here how frequent the connections between Mesa, AZ and San Diego are, during different times and days of the week.
Thursday is the busiest day, with more than 13 daily buses from Mesa, AZ to San Diego. Friday has instead the fewest connections, with only 2 daily coaches between Mesa, AZ and San Diego.
The busiest time of the day is the Evening, with 29 buses from Mesa, AZ to San Diego, while Afternoon sees the fewest connections between Mesa, AZ and San Diego, with 5 offers.

Facts about the bus from Mesa, AZ to San Diego

Compare all providers like Greyhound US that travel 6 times every day by bus from Mesa, AZ to San Diego in one click! Book your bus ticket from Mesa, AZ to San Diego starting from $64!

Cheapest Bus $64
Fastest Bus 12h 5m
Earliest Bus 1:45 PM
Latest Bus 8:10 PM
Daily Bus Routes 6 Ø
Distance 311.8 miles
Bus Companies Greyhound US

Cheapest bus connections from Mesa, AZ to San Diego

Every day, 6 buses from 1 bus companies leave Mesa, AZ for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/15/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/09
Monday 03/10
Tuesday 03/11
Wednesday 03/12
Thursday 03/13
Friday 03/14
Saturday 03/15
Sunday 03/16
$79
Monday 03/17
$64
Tuesday 03/18
$71
Wednesday 03/19
Thursday 03/20
$65
Friday 03/21
$77
Saturday 03/22
Sunday 03/23
Monday 03/24
Tuesday 03/25
Wednesday 03/26
Thursday 03/27
Friday 03/28
Saturday 03/29
Sunday 03/30
Monday 03/31
Tuesday 04/01
Wednesday 04/02
Thursday 04/03
Friday 04/04
Saturday 04/05

The cheapest time to travel from Mesa, AZ to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Mesa, AZ to San Diego, for the next 30 days.
With a price starting from $64, Monday is the cheapest day for a bus from Mesa, AZ to San Diego. Sunday instead is the most expensive day with prices starting from $79.
Evening is the cheapest day time for bus tickets from Mesa, AZ to San Diego, with $64. Afternoon is the most expensive time of the day with prices starting from $68.

How to save money travelling from Mesa, AZ to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mesa, AZ to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mesa, AZ to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mesa, AZ to San Diego are also emptier.

All bus stations and stops in Mesa, AZ and San Diego

In the map below, you can see where to find all bus stations in Mesa, AZ and San Diego.

Service and Comfort on the bus from Mesa, AZ to San Diego

Want to know which seat classes are available on the buses from Mesa, AZ to San Diego? Or which bus companies serve the route Mesa, AZ to San Diego? Below you will find answers to your questions.

FAQs about the Mesa, AZ to San Diego bus

How much does a Mesa, AZ San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $64 and takes 14h 50m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Mesa, AZ to San Diego?

This route is offered by 1 companies with a range of ticket prices between $64 and $183. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Mesa, AZ to San Diego each day?

Every day, the Mesa, AZ to San Diego bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mesa, AZ to San Diego take?

The fastest bus from Mesa, AZ to San Diego is offered by Greyhound US and takes 12h 5m. Bus tickets for this connection cost $85. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mesa, AZ to San Diego?

The earliest bus arriving in San Diego from Mesa, AZ starts at 1:45 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mesa, AZ to San Diego?

The latest bus trip departing from Mesa, AZ for San Diego starts at 8:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mesa, AZ San Diego route?

When traveling by bus from Mesa, AZ to San Diego, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mesa, AZ and San Diego?

You can check all the direct connections between Mesa, AZ and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mesa, AZ to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mesa, AZ San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mesa, AZ San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mesa, AZ to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Mesa, AZ to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mesa, AZ and to San Diego

Here’s an overview of the most popular bus routes to Mesa, AZ and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Mesa, AZ and to San Diego
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