Bus from Mesa, AZ to San Diego from $70

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Compare all timetables for the bus from Mesa, AZ to San Diego

Here is a selection of the cheapest bus trips from the schedule from Mesa, AZ to San Diego from various bus operators like Greyhound US for the next days.

today
from $87
tomorrow
from $75
Sunday
from $87
Monday
Tuesday
from $70
Wednesday
from $79
Thursday

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    13h 55m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $87

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    13h 5m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:15 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $75
  • Greyhound US
    14h 30m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    10:40 AM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $76
  • Greyhound US
    13h 20m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $76
  • Greyhound US
    19h 30m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    3:40 PM
    San Diego
    SDSU Transit Center
    0
    Greyhound US
    Economy
    $77
  • Greyhound US
    12h 35m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    8:45 AM
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    $77

Cheapest bus trips Sunday

Prices are for one way and one person
  • Greyhound US
    13h 5m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:15 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $87
  • Greyhound US
    14h 30m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    10:40 AM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $88
  • Greyhound US
    13h 20m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $88
  • Greyhound US
    12h 35m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    8:45 AM
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    $88
  • Greyhound US
    19h 30m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    3:40 PM
    San Diego
    SDSU Transit Center
    0
    Greyhound US
    Economy
    $89

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    12h 35m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    8:45 AM
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    $70
  • Greyhound US
    13h 5m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:15 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $71
  • Greyhound US
    13h 20m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $72
  • Greyhound US
    13h 55m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $74

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Greyhound US
    13h 55m
    0
    8:10 PM
    Mesa, AZ
    Greyhound
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $79

Facts about the bus from Mesa, AZ to San Diego

Compare all providers like Greyhound US that travel 3 times every day by bus from Mesa, AZ to San Diego in one click! Book your bus ticket from Mesa, AZ to San Diego starting from $70!

Cheapest Bus $70
Fastest Bus 12h 35m
Earliest Bus 8:10 PM
Latest Bus 8:10 PM
Daily Bus Routes 3 Ø
Distance 311.8 miles
Bus Companies Greyhound US

Cheapest bus connections from Mesa, AZ to San Diego

Every day, 3 buses from 1 bus companies leave Mesa, AZ for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/12/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
$87
Saturday 07/12
$80
Sunday 07/13
$87
Monday 07/14
Tuesday 07/15
$70
Wednesday 07/16
$79
Thursday 07/17
Friday 07/18
$72
Saturday 07/19
Sunday 07/20
Monday 07/21
Tuesday 07/22
Wednesday 07/23
Thursday 07/24
Friday 07/25
Saturday 07/26
Sunday 07/27
Monday 07/28
Tuesday 07/29
Wednesday 07/30
Thursday 07/31
Friday 08/01
Saturday 08/02

How to save money travelling from Mesa, AZ to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mesa, AZ to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mesa, AZ to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mesa, AZ to San Diego are also emptier.

All bus stations and stops in Mesa, AZ and San Diego

In the map below, you can see where to find all bus stations in Mesa, AZ and San Diego.

Service and Comfort on the bus from Mesa, AZ to San Diego

Want to know which seat classes are available on the buses from Mesa, AZ to San Diego? Or which bus companies serve the route Mesa, AZ to San Diego? Below you will find answers to your questions.

FAQs about the Mesa, AZ to San Diego bus

How much does a Mesa, AZ San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $70 and takes 12h 35m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Mesa, AZ to San Diego?

This route is offered by 1 companies with a range of ticket prices between $70 and $89. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Mesa, AZ to San Diego each day?

Every day, the Mesa, AZ to San Diego bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mesa, AZ to San Diego take?

The fastest bus from Mesa, AZ to San Diego is offered by Greyhound US and takes 12h 35m. Bus tickets for this connection cost $77. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mesa, AZ to San Diego?

The earliest bus arriving in San Diego from Mesa, AZ starts at 8:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mesa, AZ to San Diego?

The latest bus trip departing from Mesa, AZ for San Diego starts at 8:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mesa, AZ San Diego route?

When traveling by bus from Mesa, AZ to San Diego, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mesa, AZ and San Diego?

You can check all the direct connections between Mesa, AZ and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mesa, AZ to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mesa, AZ San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mesa, AZ San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mesa, AZ to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Mesa, AZ to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mesa, AZ and to San Diego

Here’s an overview of the most popular bus routes to Mesa, AZ and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus from San Jose, CA to San Diego Bus from San Jose, CA to San Diego
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Popular Airport Shuttles to Mesa, AZ and to San Diego
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