Bus Mexico City to Mezcales - Compare all Companies

Compare all timetables for the bus from Mexico City to Mezcales

Here is a selection of the cheapest bus trips from the schedule from Mexico City to Mezcales from various bus operators like Futura, Primera Plus or ETN Autobuses for the next days.

today

$104

tomorrow

$104

Wednesday

$104

Thursday

$104

Friday

$104

Saturday

$104

Sunday

$104

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	10h 35m	8:00 PM	Mexico City	Norte Bus Station	6:35 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/19/2026 8:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/20/2026 6:35:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 35m
Primera Plus	10h 30m	9:00 PM	Mexico City	Norte Bus Station	7:30 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/19/2026 9:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/20/2026 7:30:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 30m
Futura	12h 10m	6:00 PM	Mexico City	Norte Bus Station	6:10 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/19/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/20/2026 6:10:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 10m
Futura	12h 30m	9:00 PM	Mexico City	Norte Bus Station	9:30 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/19/2026 9:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/20/2026 9:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 30m
ETN Autobuses	11h 40m	9:00 PM	Mexico City	Norte Bus Station	8:40 AM	Mezcales	Vallarte Plus	Premium Economy	$143	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 1/19/2026 9:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/20/2026 8:40:00 AM. 50 Premium Economy ticket for $143 per person are available. Travel duration is 11h 40m

Did you know that if you travel from Mexico City to Mezcales via Guadalajara, JC, you can save more than $27? You can find the corresponding connections below.
- Busbud
  
  13h 36m
  
  0
  
  9:00 AM
  
  Mexico City
  
  4:30 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  0
  
  Premium Economy
  
  $35
  
  A Bus from Busbud goes from , Mexico City (Mexico) at 1/20/2026 9:00:00 AM to Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) arriving at 1/20/2026 4:30:00 PM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 7h 30m
- ClickBus MX
  
  4h 36m
  
  0
  
  6:00 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  10:36 PM
  
  Mezcales
  Primera Plus
  
  0
  
  Economy
  
  $42
  
  A Bus from ClickBus MX goes from Central de Autobuses, Guadalajara, JC (Mexico) at 1/20/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/20/2026 10:36:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 4h 36m
Travel time is 3h 6m longer, but you will save $27

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	10h 35m	8:00 PM	Mexico City	Norte Bus Station	6:35 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/20/2026 8:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/21/2026 6:35:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 35m
Primera Plus	10h 30m	9:00 PM	Mexico City	Norte Bus Station	7:30 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/20/2026 9:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/21/2026 7:30:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 30m
Futura	12h 10m	6:00 PM	Mexico City	Norte Bus Station	6:10 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/20/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/21/2026 6:10:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 10m
Futura	12h 30m	9:00 PM	Mexico City	Norte Bus Station	9:30 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/20/2026 9:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/21/2026 9:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 30m
Futura	12h 30m	10:30 PM	Mexico City	Norte Bus Station	11:00 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/20/2026 10:30:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/21/2026 11:00:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 30m

Did you know that if you travel from Mexico City to Mezcales via Guadalajara, JC, you can save more than $27? You can find the corresponding connections below.
- Busbud
  
  13h 36m
  
  0
  
  9:00 AM
  
  Mexico City
  
  4:30 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  0
  
  Premium Economy
  
  $35
  
  A Bus from Busbud goes from , Mexico City (Mexico) at 1/20/2026 9:00:00 AM to Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) arriving at 1/20/2026 4:30:00 PM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 7h 30m
- ClickBus MX
  
  4h 36m
  
  0
  
  6:00 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  10:36 PM
  
  Mezcales
  Primera Plus
  
  0
  
  Economy
  
  $42
  
  A Bus from ClickBus MX goes from Central de Autobuses, Guadalajara, JC (Mexico) at 1/20/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/20/2026 10:36:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 4h 36m
Travel time is 3h 6m longer, but you will save $27

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	10h 35m	8:00 PM	Mexico City	Norte Bus Station	6:35 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/21/2026 8:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/22/2026 6:35:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 35m
Primera Plus	10h 30m	9:00 PM	Mexico City	Norte Bus Station	7:30 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/21/2026 9:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/22/2026 7:30:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 30m
Futura	732h 10m	6:00 PM	Mexico City	Norte Bus Station	6:10 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/21/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 2/21/2026 6:10:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 732h 10m
Futura	252h 30m	9:00 PM	Mexico City	Norte Bus Station	9:30 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/21/2026 9:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 2/1/2026 9:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 252h 30m
ETN Autobuses	11h 40m	9:00 PM	Mexico City	Norte Bus Station	8:40 AM	Mezcales	Vallarte Plus	Premium Economy	$152	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 1/21/2026 9:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/22/2026 8:40:00 AM. 50 Premium Economy ticket for $152 per person are available. Travel duration is 11h 40m

Did you know that if you travel from Mexico City to Mezcales via Guadalajara, JC, you can save more than $27? You can find the corresponding connections below.
- Busbud
  
  13h 36m
  
  0
  
  9:00 AM
  
  Mexico City
  
  4:30 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  0
  
  Premium Economy
  
  $35
  
  A Bus from Busbud goes from , Mexico City (Mexico) at 1/20/2026 9:00:00 AM to Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) arriving at 1/20/2026 4:30:00 PM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 7h 30m
- ClickBus MX
  
  4h 36m
  
  0
  
  6:00 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  10:36 PM
  
  Mezcales
  Primera Plus
  
  0
  
  Economy
  
  $42
  
  A Bus from ClickBus MX goes from Central de Autobuses, Guadalajara, JC (Mexico) at 1/20/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/20/2026 10:36:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 4h 36m
Travel time is 3h 6m longer, but you will save $27

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	10h 35m	8:00 PM	Mexico City	Norte Bus Station	6:35 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/22/2026 8:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/23/2026 6:35:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 35m
Primera Plus	10h 30m	9:00 PM	Mexico City	Norte Bus Station	7:30 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/22/2026 9:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/23/2026 7:30:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 30m
Futura	12h 10m	6:00 PM	Mexico City	Norte Bus Station	6:10 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/22/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/23/2026 6:10:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 10m
Futura	12h 30m	9:00 PM	Mexico City	Norte Bus Station	9:30 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/22/2026 9:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/23/2026 9:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 30m
Futura	12h 30m	10:30 PM	Mexico City	Norte Bus Station	11:00 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/22/2026 10:30:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/23/2026 11:00:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 30m

Did you know that if you travel from Mexico City to Mezcales via Guadalajara, JC, you can save more than $27? You can find the corresponding connections below.
- Busbud
  
  13h 36m
  
  0
  
  9:00 AM
  
  Mexico City
  
  4:30 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  0
  
  Premium Economy
  
  $35
  
  A Bus from Busbud goes from , Mexico City (Mexico) at 1/20/2026 9:00:00 AM to Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) arriving at 1/20/2026 4:30:00 PM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 7h 30m
- ClickBus MX
  
  4h 36m
  
  0
  
  6:00 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  10:36 PM
  
  Mezcales
  Primera Plus
  
  0
  
  Economy
  
  $42
  
  A Bus from ClickBus MX goes from Central de Autobuses, Guadalajara, JC (Mexico) at 1/20/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/20/2026 10:36:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 4h 36m
Travel time is 3h 6m longer, but you will save $27

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	10h 35m	8:00 PM	Mexico City	Norte Bus Station	6:35 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/23/2026 8:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/24/2026 6:35:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 35m
Primera Plus	10h 30m	9:00 PM	Mexico City	Norte Bus Station	7:30 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/23/2026 9:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/24/2026 7:30:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 30m
Futura	12h 10m	6:00 PM	Mexico City	Norte Bus Station	6:10 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/23/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/24/2026 6:10:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 10m
Futura	12h 30m	9:00 PM	Mexico City	Norte Bus Station	9:30 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/23/2026 9:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/24/2026 9:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 30m
ETN Autobuses	11h 40m	9:00 PM	Mexico City	Norte Bus Station	8:40 AM	Mezcales	Vallarte Plus	Premium Economy	$152	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 1/23/2026 9:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/24/2026 8:40:00 AM. 50 Premium Economy ticket for $152 per person are available. Travel duration is 11h 40m

Did you know that if you travel from Mexico City to Mezcales via Guadalajara, JC, you can save more than $27? You can find the corresponding connections below.
- Busbud
  
  13h 36m
  
  0
  
  9:00 AM
  
  Mexico City
  
  4:30 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  0
  
  Premium Economy
  
  $35
  
  A Bus from Busbud goes from , Mexico City (Mexico) at 1/20/2026 9:00:00 AM to Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) arriving at 1/20/2026 4:30:00 PM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 7h 30m
- ClickBus MX
  
  4h 36m
  
  0
  
  6:00 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  10:36 PM
  
  Mezcales
  Primera Plus
  
  0
  
  Economy
  
  $42
  
  A Bus from ClickBus MX goes from Central de Autobuses, Guadalajara, JC (Mexico) at 1/20/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/20/2026 10:36:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 4h 36m
Travel time is 3h 6m longer, but you will save $27

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	10h 35m	8:00 PM	Mexico City	Norte Bus Station	6:35 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/24/2026 8:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/25/2026 6:35:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 35m
Primera Plus	10h 30m	9:00 PM	Mexico City	Norte Bus Station	7:30 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/24/2026 9:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/25/2026 7:30:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 30m
Futura	12h 10m	6:00 PM	Mexico City	Norte Bus Station	6:10 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/24/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/25/2026 6:10:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 10m
Futura	12h 30m	9:00 PM	Mexico City	Norte Bus Station	9:30 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/24/2026 9:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/25/2026 9:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 30m
Futura	12h 30m	10:30 PM	Mexico City	Norte Bus Station	11:00 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/24/2026 10:30:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/25/2026 11:00:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 30m

Did you know that if you travel from Mexico City to Mezcales via Guadalajara, JC, you can save more than $27? You can find the corresponding connections below.
- Busbud
  
  13h 36m
  
  0
  
  9:00 AM
  
  Mexico City
  
  4:30 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  0
  
  Premium Economy
  
  $35
  
  A Bus from Busbud goes from , Mexico City (Mexico) at 1/20/2026 9:00:00 AM to Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) arriving at 1/20/2026 4:30:00 PM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 7h 30m
- ClickBus MX
  
  4h 36m
  
  0
  
  6:00 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  10:36 PM
  
  Mezcales
  Primera Plus
  
  0
  
  Economy
  
  $42
  
  A Bus from ClickBus MX goes from Central de Autobuses, Guadalajara, JC (Mexico) at 1/20/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/20/2026 10:36:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 4h 36m
Travel time is 3h 6m longer, but you will save $27

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	10h 35m	8:00 PM	Mexico City	Norte Bus Station	6:35 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/25/2026 8:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/26/2026 6:35:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 35m
Primera Plus	10h 30m	9:00 PM	Mexico City	Norte Bus Station	7:30 AM	Mezcales	Vallarte Plus	Economy	$104	A Bus from Primera Plus goes from Norte Bus Station, Mexico City (Mexico) at 1/25/2026 9:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/26/2026 7:30:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 30m
Futura	12h 10m	6:00 PM	Mexico City	Norte Bus Station	6:10 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/25/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/26/2026 6:10:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 10m
Futura	12h 30m	9:00 PM	Mexico City	Norte Bus Station	9:30 AM	Mezcales	Primera Plus	Economy	$112	A Bus from Futura goes from Norte Bus Station, Mexico City (Mexico) at 1/25/2026 9:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/26/2026 9:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 12h 30m
ETN Autobuses	11h 40m	9:00 PM	Mexico City	Norte Bus Station	8:40 AM	Mezcales	Vallarte Plus	Premium Economy	$152	A Bus from ETN Autobuses goes from Norte Bus Station, Mexico City (Mexico) at 1/25/2026 9:00:00 PM to Vallarte Plus, Mezcales (Mexico) arriving at 1/26/2026 8:40:00 AM. 50 Premium Economy ticket for $152 per person are available. Travel duration is 11h 40m

Did you know that if you travel from Mexico City to Mezcales via Guadalajara, JC, you can save more than $27? You can find the corresponding connections below.
- Busbud
  
  13h 36m
  
  0
  
  9:00 AM
  
  Mexico City
  
  4:30 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  0
  
  Premium Economy
  
  $35
  
  A Bus from Busbud goes from , Mexico City (Mexico) at 1/20/2026 9:00:00 AM to Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) arriving at 1/20/2026 4:30:00 PM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 7h 30m
- ClickBus MX
  
  4h 36m
  
  0
  
  6:00 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  10:36 PM
  
  Mezcales
  Primera Plus
  
  0
  
  Economy
  
  $42
  
  A Bus from ClickBus MX goes from Central de Autobuses, Guadalajara, JC (Mexico) at 1/20/2026 6:00:00 PM to Primera Plus, Mezcales (Mexico) arriving at 1/20/2026 10:36:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 4h 36m
Travel time is 3h 6m longer, but you will save $27

Best Price Offer: The price for the cheapest bus from Mexico City to Mezcales is $104 on 1/19/2026. Flexible travelers save on ticket prices.

Facts about the bus from Mexico City to Mezcales

Compare all providers like Futura, Primera Plus and ETN Autobuses that travel 6 times every day by bus from Mexico City to Mezcales in one click! Book your bus ticket from Mexico City to Mezcales starting from $104!

Cheapest Bus	$104
Fastest Bus	10h 30m
Earliest Bus	6:00 PM
Latest Bus	10:40 PM
Daily Bus Routes	6 Ø
Distance	409.1 miles
Bus Companies	Futura, Primera Plus and ETN Autobuses

Cheapest bus connections from Mexico City to Mezcales

Every day, 6 buses from 3 bus companies leave Mexico City for Mezcales: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

$104

Tuesday 01/20

$112

Wednesday 01/21

$112

Thursday 01/22

$104

Friday 01/23

$104

Saturday 01/24

$112

Sunday 01/25

$104

Monday 01/26

$112

Tuesday 01/27

$112

Wednesday 01/28

$104

Thursday 01/29

$112

Friday 01/30

$104

Saturday 01/31

$104

Sunday 02/01

$112

Monday 02/02

$112

Tuesday 02/03

$112

Wednesday 02/04

$104

Thursday 02/05

$112

Friday 02/06

$104

Saturday 02/07

$112

Sunday 02/08

$104

Monday 02/09

$112

Tuesday 02/10

$112

Wednesday 02/11

$112

Thursday 02/12

$112

Friday 02/13

$104

Saturday 02/14

How to save money travelling from Mexico City to Mezcales

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mexico City to Mezcales in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mexico City to Mezcales, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mexico City to Mezcales are also emptier.

Beloved bus companies from Mexico City to Mezcales

These are the most booked bus companies between Mexico City to Mezcales from our users.

Futura from Mexico City to Mezcales

Here you will find the key facts about the Futura bus route Mexico City to Mezcales:

Cheapest Price	$112
Fastest Bus	12h 10m
Earliest Bus	6:00 PM
Last Bus	10:30 PM
Daily Connections	2 Ø
Found on	1/19/2026

Primera Plus from Mexico City to Mezcales

Here you will find the key facts about the Primera Plus bus route Mexico City to Mezcales:

Cheapest Price	$104
Fastest Bus	10h 30m
Earliest Bus	8:00 PM
Last Bus	9:00 PM
Daily Connections	2 Ø
Found on	1/19/2026

ETN Autobuses from Mexico City to Mezcales

Here you will find the key facts about the ETN Autobuses bus route Mexico City to Mezcales:

Cheapest Price	$143
Fastest Bus	11h 40m
Earliest Bus	9:00 PM
Last Bus	10:40 PM
Daily Connections	2 Ø
Found on	12/28/2025

All bus stations and stops in Mexico City and Mezcales

In the map below, you can see where to find all bus stations in Mexico City and Mezcales.

Norte Bus Station

Eje Central Lázaro Cárdenas

Terminal de Autobuses de Oriente (TAPO)

Calz. Ignacio Zaragoza 200

Terminal del Sur

Av. Taxqueña 1320

Observatorio Central Bus Station

Av Río de Tacubaya 122 232

Terminal Antas Tla

Emiliano Zapata 97

Primera Plus

Blvrd Riviera Nayarit 171

Service and Comfort on the bus from Mexico City to Mezcales

Want to know which seat classes are available on the buses from Mexico City to Mezcales? Or which bus companies serve the route Mexico City to Mezcales? Below you will find answers to your questions.

FAQs about the Mexico City to Mezcales bus

How much does a Mexico City Mezcales bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $104 and takes 10h 35m to reach Mezcales. Compare offers to save money!

How much could I save by comparing buses from Mexico City to Mezcales?

This route is offered by 3 companies with a range of ticket prices between $104 and $152. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mezcales.

On average, how many connections are available from Mexico City to Mezcales each day?

Every day, the Mexico City to Mezcales bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mexico City to Mezcales take?

The fastest bus from Mexico City to Mezcales is offered by Primera Plus and takes 10h 30m. Bus tickets for this connection cost $104. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mexico City to Mezcales?

The earliest bus arriving in Mezcales from Mexico City starts at 6:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mexico City to Mezcales?

The latest bus trip departing from Mexico City for Mezcales starts at 10:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mexico City Mezcales route?

When traveling by bus from Mexico City to Mezcales, passengers can travel with Futura, Primera Plus and ETN Autobuses. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mexico City and Mezcales?

You can check all the direct connections between Mexico City and Mezcales by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Futura, Primera Plus and ETN Autobuses.

What can I take with me on the Mexico City to Mezcales bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mexico City Mezcales bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mexico City Mezcales bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mexico City to Mezcales on your planned travel date.

How does CheckMyBus find the best bus deals from Mexico City to Mezcales?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Mexico City and Mezcales. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mexico City to Mezcales?

Prices and availability for 6 trips between Mexico City and Mezcales change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mexico City to Mezcales

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Mexico City and to Mezcales

Here’s an overview of the most popular bus routes to Mexico City and to Mezcales. Simply click on the connection of your choice, and you will find all the details about your bus route!