Bus San Diego to Mexico City: Compare prices and save money

Compare all timetables for the bus from San Diego to Mexico City

Here is a selection of the cheapest bus trips from the schedule from San Diego to Mexico City from various bus operators like FlixBus or Greyhound US for the next days.

today

$252

tomorrow

$237

Wednesday

$237

Thursday

$230

Friday

$223

Saturday

$224

Sunday

$252

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	62h 15m	1:45 PM	San Diego	Seaport Village	6:00 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$252	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 12/22/2025 1:45:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/25/2025 6:00:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 62h 15m
FlixBus	61h 50m	1:45 PM	San Diego	Seaport Village	5:35 AM	Mexico City	Fórum Buenavista	Economy	$252	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 12/22/2025 1:45:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/25/2025 5:35:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 61h 50m
FlixBus	63h 45m	12:15 PM	San Diego	Old Town Transit Center	6:00 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$254	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 12/22/2025 12:15:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/25/2025 6:00:00 AM. 50 Economy ticket for $254 per person are available. Travel duration is 63h 45m
Greyhound US	67h 15m	7:35 PM	San Diego	Old Town Transit Center	4:50 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$264	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/22/2025 7:35:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/25/2025 4:50:00 PM. 50 Economy ticket for $264 per person are available. Travel duration is 67h 15m
Greyhound US	66h 55m	7:35 PM	San Diego	Old Town Transit Center	4:30 PM	Mexico City	Fórum Buenavista	Economy	$264	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/22/2025 7:35:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/25/2025 4:30:00 PM. 50 Economy ticket for $264 per person are available. Travel duration is 66h 55m

Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $106? You can find the corresponding connections below.
- Busbud
  
  51h 49m
  
  0
  
  12:01 AM
  
  San Diego
  Old Town Transit Center
  
  2:25 AM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $9
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 12/24/2025 12:01:00 AM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 12/24/2025 2:25:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 24m
- Busbud
  
  42h 10m
  
  0
  
  9:40 AM
  
  Tijuana, BC
  Centro Bus Stop
  
  5:50 AM
  
  Mexico City
  Instituto Politécnico Nacional Bus Stop
  
  0
  
  Economy
  
  $137
  
  A Bus from Busbud goes from Centro Bus Stop, Tijuana, BC (Mexico) at 12/24/2025 9:40:00 AM to Instituto Politécnico Nacional Bus Stop, Mexico City (Mexico) arriving at 12/26/2025 5:50:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 42h 10m
Travel Time is 12h 1m shorter, and you will save $106

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	63h 20m	12:15 PM	San Diego	Old Town Transit Center	5:35 AM	Mexico City	Fórum Buenavista	Economy	$237	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 12/23/2025 12:15:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/26/2025 5:35:00 AM. 50 Economy ticket for $237 per person are available. Travel duration is 63h 20m
FlixBus	63h 45m	12:15 PM	San Diego	Old Town Transit Center	6:00 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$237	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 12/23/2025 12:15:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/26/2025 6:00:00 AM. 50 Economy ticket for $237 per person are available. Travel duration is 63h 45m
FlixBus	62h 15m	1:45 PM	San Diego	Seaport Village	6:00 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$237	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 12/23/2025 1:45:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/26/2025 6:00:00 AM. 50 Economy ticket for $237 per person are available. Travel duration is 62h 15m
Greyhound US	68h 50m	6:45 AM	San Diego	Old Town Transit Center	5:35 AM	Mexico City	Fórum Buenavista	Economy	$238	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/23/2025 6:45:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/26/2025 5:35:00 AM. 50 Economy ticket for $238 per person are available. Travel duration is 68h 50m
Greyhound US	69h 15m	6:45 AM	San Diego	Old Town Transit Center	6:00 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$238	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/23/2025 6:45:00 AM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/26/2025 6:00:00 AM. 50 Economy ticket for $238 per person are available. Travel duration is 69h 15m

Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $91? You can find the corresponding connections below.
- Busbud
  
  51h 49m
  
  0
  
  12:01 AM
  
  San Diego
  Old Town Transit Center
  
  2:25 AM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $9
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 12/24/2025 12:01:00 AM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 12/24/2025 2:25:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 24m
- Busbud
  
  42h 10m
  
  0
  
  9:40 AM
  
  Tijuana, BC
  Centro Bus Stop
  
  5:50 AM
  
  Mexico City
  Instituto Politécnico Nacional Bus Stop
  
  0
  
  Economy
  
  $137
  
  A Bus from Busbud goes from Centro Bus Stop, Tijuana, BC (Mexico) at 12/24/2025 9:40:00 AM to Instituto Politécnico Nacional Bus Stop, Mexico City (Mexico) arriving at 12/26/2025 5:50:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 42h 10m
Travel Time is 12h 26m shorter, and you will save $91

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	75h 10m	7:00 PM	San Diego	San Ysidro Transit Center	12:10 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$237	A Bus from Greyhound US goes from San Ysidro Transit Center, San Diego (USA) at 12/24/2025 7:00:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/28/2025 12:10:00 AM. 50 Economy ticket for $237 per person are available. Travel duration is 75h 10m
FlixBus	63h 20m	12:15 PM	San Diego	Old Town Transit Center	5:35 AM	Mexico City	Fórum Buenavista	Economy	$242	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 12/24/2025 12:15:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/27/2025 5:35:00 AM. 50 Economy ticket for $242 per person are available. Travel duration is 63h 20m
FlixBus	61h 25m	2:10 PM	San Diego	La Jolla Village	5:35 AM	Mexico City	Fórum Buenavista	Economy	$242	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 12/24/2025 2:10:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/27/2025 5:35:00 AM. 50 Economy ticket for $242 per person are available. Travel duration is 61h 25m
FlixBus	61h 50m	1:45 PM	San Diego	Seaport Village	5:35 AM	Mexico City	Fórum Buenavista	Economy	$242	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 12/24/2025 1:45:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/27/2025 5:35:00 AM. 50 Economy ticket for $242 per person are available. Travel duration is 61h 50m
Greyhound US	68h 50m	6:45 AM	San Diego	Old Town Transit Center	5:35 AM	Mexico City	Fórum Buenavista	Economy	$243	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/24/2025 6:45:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/27/2025 5:35:00 AM. 50 Economy ticket for $243 per person are available. Travel duration is 68h 50m

Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $91? You can find the corresponding connections below.
- Busbud
  
  51h 49m
  
  0
  
  12:01 AM
  
  San Diego
  Old Town Transit Center
  
  2:25 AM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $9
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 12/24/2025 12:01:00 AM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 12/24/2025 2:25:00 AM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 24m
- Busbud
  
  42h 10m
  
  0
  
  9:40 AM
  
  Tijuana, BC
  Centro Bus Stop
  
  5:50 AM
  
  Mexico City
  Instituto Politécnico Nacional Bus Stop
  
  0
  
  Economy
  
  $137
  
  A Bus from Busbud goes from Centro Bus Stop, Tijuana, BC (Mexico) at 12/24/2025 9:40:00 AM to Instituto Politécnico Nacional Bus Stop, Mexico City (Mexico) arriving at 12/26/2025 5:50:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 42h 10m
Travel Time is 11h 36m shorter, and you will save $91

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	61h 40m	7:35 AM	San Diego	Old Town Transit Center	11:15 PM	Mexico City	Fórum Buenavista	Economy	$230	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 12/25/2025 7:35:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/27/2025 11:15:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 61h 40m
FlixBus	61h 20m	7:55 AM	San Diego	La Jolla Village	11:15 PM	Mexico City	Fórum Buenavista	Economy	$230	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 12/25/2025 7:55:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/27/2025 11:15:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 61h 20m
Greyhound US	59h 50m	9:25 AM	San Diego	San Ysidro Transit Center	11:15 PM	Mexico City	Fórum Buenavista	Economy	$230	A Bus from Greyhound US goes from San Ysidro Transit Center, San Diego (USA) at 12/25/2025 9:25:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/27/2025 11:15:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 59h 50m
Greyhound US	59h 15m	10:00 AM	San Diego	Old Town Transit Center	11:15 PM	Mexico City	Fórum Buenavista	Economy	$232	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/25/2025 10:00:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/27/2025 11:15:00 PM. 50 Economy ticket for $232 per person are available. Travel duration is 59h 15m
FlixBus	62h 15m	1:45 PM	San Diego	Seaport Village	6:00 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$260	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 12/25/2025 1:45:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/28/2025 6:00:00 AM. 50 Economy ticket for $260 per person are available. Travel duration is 62h 15m

Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $86? You can find the corresponding connections below.
- Busbud
  
  51h 49m
  
  0
  
  12:01 AM
  
  San Diego
  Old Town Transit Center
  
  2:25 AM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 12/27/2025 12:01:00 AM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 12/27/2025 2:25:00 AM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 24m
- Busbud
  
  42h 10m
  
  0
  
  9:40 AM
  
  Tijuana, BC
  Centro Bus Stop
  
  5:50 AM
  
  Mexico City
  Instituto Politécnico Nacional Bus Stop
  
  0
  
  Economy
  
  $137
  
  A Bus from Busbud goes from Centro Bus Stop, Tijuana, BC (Mexico) at 12/27/2025 9:40:00 AM to Instituto Politécnico Nacional Bus Stop, Mexico City (Mexico) arriving at 12/29/2025 5:50:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 42h 10m
Travel Time is 9h 26m shorter, and you will save $86

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	60h 15m	9:25 AM	San Diego	San Ysidro Transit Center	11:40 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$223	A Bus from Greyhound US goes from San Ysidro Transit Center, San Diego (USA) at 12/26/2025 9:25:00 AM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/28/2025 11:40:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 60h 15m
Greyhound US	59h 50m	9:25 AM	San Diego	San Ysidro Transit Center	11:15 PM	Mexico City	Fórum Buenavista	Economy	$223	A Bus from Greyhound US goes from San Ysidro Transit Center, San Diego (USA) at 12/26/2025 9:25:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/28/2025 11:15:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 59h 50m
FlixBus	62h 45m	1:15 PM	San Diego	San Ysidro Transit Center	6:00 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$247	A Bus from FlixBus goes from San Ysidro Transit Center, San Diego (USA) at 12/26/2025 1:15:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/29/2025 6:00:00 AM. 50 Economy ticket for $247 per person are available. Travel duration is 62h 45m
FlixBus	62h 20m	1:15 PM	San Diego	San Ysidro Transit Center	5:35 AM	Mexico City	Fórum Buenavista	Economy	$247	A Bus from FlixBus goes from San Ysidro Transit Center, San Diego (USA) at 12/26/2025 1:15:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/29/2025 5:35:00 AM. 50 Economy ticket for $247 per person are available. Travel duration is 62h 20m
Greyhound US	64h 25m	7:00 PM	San Diego	San Ysidro Transit Center	1:25 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$290	A Bus from Greyhound US goes from San Ysidro Transit Center, San Diego (USA) at 12/26/2025 7:00:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/29/2025 1:25:00 PM. 50 Economy ticket for $290 per person are available. Travel duration is 64h 25m

Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $80? You can find the corresponding connections below.
- Busbud
  
  82h 25m
  
  0
  
  5:55 PM
  
  San Diego
  Old Town Transit Center
  
  8:05 PM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 12/26/2025 5:55:00 PM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 12/26/2025 8:05:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 10m
- Busbud
  
  42h 40m
  
  0
  
  9:40 AM
  
  Tijuana, BC
  Centro Bus Stop
  
  6:20 AM
  
  Mexico City
  Calz. Ignacio Zaragoza
  
  0
  
  Economy
  
  $136
  
  A Bus from Busbud goes from Centro Bus Stop, Tijuana, BC (Mexico) at 12/28/2025 9:40:00 AM to Calz. Ignacio Zaragoza, Mexico City (Mexico) arriving at 12/30/2025 6:20:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 42h 40m
Travel time is 20h 35m longer, but you will save $80

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	62h 45m	1:15 PM	San Diego	San Ysidro Transit Center	6:00 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$224	A Bus from FlixBus goes from San Ysidro Transit Center, San Diego (USA) at 12/27/2025 1:15:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/30/2025 6:00:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 62h 45m
FlixBus	62h 20m	1:15 PM	San Diego	San Ysidro Transit Center	5:35 AM	Mexico City	Fórum Buenavista	Economy	$224	A Bus from FlixBus goes from San Ysidro Transit Center, San Diego (USA) at 12/27/2025 1:15:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/30/2025 5:35:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 62h 20m
Greyhound US	60h 15m	9:25 AM	San Diego	San Ysidro Transit Center	11:40 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$267	A Bus from Greyhound US goes from San Ysidro Transit Center, San Diego (USA) at 12/27/2025 9:25:00 AM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/29/2025 11:40:00 PM. 50 Economy ticket for $267 per person are available. Travel duration is 60h 15m
Greyhound US	59h 50m	9:25 AM	San Diego	San Ysidro Transit Center	11:15 PM	Mexico City	Fórum Buenavista	Economy	$267	A Bus from Greyhound US goes from San Ysidro Transit Center, San Diego (USA) at 12/27/2025 9:25:00 AM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/29/2025 11:15:00 PM. 50 Economy ticket for $267 per person are available. Travel duration is 59h 50m
Greyhound US	64h 25m	7:00 PM	San Diego	San Ysidro Transit Center	1:25 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$300	A Bus from Greyhound US goes from San Ysidro Transit Center, San Diego (USA) at 12/27/2025 7:00:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/30/2025 1:25:00 PM. 50 Economy ticket for $300 per person are available. Travel duration is 64h 25m

Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $81? You can find the corresponding connections below.
- Busbud
  
  82h 25m
  
  0
  
  5:55 PM
  
  San Diego
  Old Town Transit Center
  
  8:05 PM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 12/26/2025 5:55:00 PM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 12/26/2025 8:05:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 10m
- Busbud
  
  42h 40m
  
  0
  
  9:40 AM
  
  Tijuana, BC
  Centro Bus Stop
  
  6:20 AM
  
  Mexico City
  Calz. Ignacio Zaragoza
  
  0
  
  Economy
  
  $136
  
  A Bus from Busbud goes from Centro Bus Stop, Tijuana, BC (Mexico) at 12/28/2025 9:40:00 AM to Calz. Ignacio Zaragoza, Mexico City (Mexico) arriving at 12/30/2025 6:20:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 42h 40m
Travel time is 20h 35m longer, but you will save $81

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	70h 55m	3:55 PM	San Diego	Old Town Transit Center	4:50 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$252	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 12/28/2025 3:55:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/31/2025 4:50:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 70h 55m
FlixBus	70h 35m	3:55 PM	San Diego	Old Town Transit Center	4:30 PM	Mexico City	Fórum Buenavista	Economy	$252	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 12/28/2025 3:55:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/31/2025 4:30:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 70h 35m
Greyhound US	67h 15m	7:35 PM	San Diego	Old Town Transit Center	4:50 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$253	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/28/2025 7:35:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/31/2025 4:50:00 PM. 50 Economy ticket for $253 per person are available. Travel duration is 67h 15m
Greyhound US	66h 55m	7:35 PM	San Diego	Old Town Transit Center	4:30 PM	Mexico City	Fórum Buenavista	Economy	$253	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 12/28/2025 7:35:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 12/31/2025 4:30:00 PM. 50 Economy ticket for $253 per person are available. Travel duration is 66h 55m
Greyhound US	67h 50m	7:00 PM	San Diego	San Ysidro Transit Center	4:50 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$255	A Bus from Greyhound US goes from San Ysidro Transit Center, San Diego (USA) at 12/28/2025 7:00:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 12/31/2025 4:50:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 67h 50m

Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $109? You can find the corresponding connections below.
- Busbud
  
  82h 25m
  
  0
  
  5:55 PM
  
  San Diego
  Old Town Transit Center
  
  8:05 PM
  
  Tijuana, BC
  CHEVRON Gas Station
  
  0
  
  Economy
  
  $7
  
  A Bus from Busbud goes from Old Town Transit Center, San Diego (USA) at 12/26/2025 5:55:00 PM to CHEVRON Gas Station, Tijuana, BC (Mexico) arriving at 12/26/2025 8:05:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 10m
- Busbud
  
  42h 40m
  
  0
  
  9:40 AM
  
  Tijuana, BC
  Centro Bus Stop
  
  6:20 AM
  
  Mexico City
  Calz. Ignacio Zaragoza
  
  0
  
  Economy
  
  $136
  
  A Bus from Busbud goes from Centro Bus Stop, Tijuana, BC (Mexico) at 12/28/2025 9:40:00 AM to Calz. Ignacio Zaragoza, Mexico City (Mexico) arriving at 12/30/2025 6:20:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 42h 40m
Travel time is 13h 30m longer, but you will save $109

Best Price Offer: The price for the cheapest bus from San Diego to Mexico City is $222 on 1/16/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Diego and Mexico City

See here how frequent the connections between San Diego and Mexico City are, during different times and days of the week.

Thursday is the busiest day, with more than 32 daily buses from San Diego to Mexico City. Friday has instead the fewest connections, with only 6 daily coaches between San Diego and Mexico City.

The busiest time of the day is the Afternoon, with 44 buses from San Diego to Mexico City, while Evening sees the fewest connections between San Diego and Mexico City, with 25 offers.

Facts about the bus from San Diego to Mexico City

Compare all providers like FlixBus and Greyhound US that travel 13 times every day by bus from San Diego to Mexico City in one click! Book your bus ticket from San Diego to Mexico City starting from $222!

Cheapest Bus	$222
Fastest Bus	61h 15m
Earliest Bus	12:15 PM
Latest Bus	7:35 PM
Daily Bus Routes	13 Ø
Distance	1,443.3 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from San Diego to Mexico City

Every day, 13 buses from 2 bus companies leave San Diego for Mexico City: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/22/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/21

Monday 12/22

$372

Tuesday 12/23

$270

Wednesday 12/24

$237

Thursday 12/25

$230

Friday 12/26

$223

Saturday 12/27

$224

Sunday 12/28

$255

Monday 12/29

$230

Tuesday 12/30

$223

Wednesday 12/31

$223

Thursday 01/01

$225

Friday 01/02

$248

Saturday 01/03

$223

Sunday 01/04

$223

Monday 01/05

$225

Tuesday 01/06

$223

Wednesday 01/07

$223

Thursday 01/08

$223

Friday 01/09

$227

Saturday 01/10

$223

Sunday 01/11

Monday 01/12

$227

Tuesday 01/13

Wednesday 01/14

$223

Thursday 01/15

$223

Friday 01/16

$222

Saturday 01/17

The cheapest time to travel from San Diego to Mexico City

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to Mexico City, for the next 30 days.

With a price starting from $222, Friday is the cheapest day for a bus from San Diego to Mexico City. Monday instead is the most expensive day with prices starting from $225.

Morning is the cheapest day time for bus tickets from San Diego to Mexico City, with $223. Evening is the most expensive time of the day with prices starting from $237.

How to save money travelling from San Diego to Mexico City

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to Mexico City in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to Mexico City, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to Mexico City are also emptier.

Beloved bus companies from San Diego to Mexico City

These are the most booked bus companies between San Diego to Mexico City from our users.

Greyhound US from San Diego to Mexico City

Here you will find the key facts about the Greyhound US bus route San Diego to Mexico City:

Cheapest Price	$223
Fastest Bus	61h 15m
Earliest Bus	7:00 PM
Last Bus	7:35 PM
Daily Connections	5 Ø
Found on	12/22/2025

All bus stations and stops in San Diego and Mexico City

In the map below, you can see where to find all bus stations in San Diego and Mexico City.

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Norte Bus Station

Eje Central Lázaro Cárdenas

Terminal de Autobuses de Oriente (TAPO)

Calz. Ignacio Zaragoza 200

Terminal del Sur

Av. Taxqueña 1320

Observatorio Central Bus Station

Av Río de Tacubaya 122 232

Terminal Antas Tla

Emiliano Zapata 97

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from San Diego to Mexico City? Compare all modes of transports from San Diego to Mexico City.

Service and Comfort on the bus from San Diego to Mexico City

Want to know which seat classes are available on the buses from San Diego to Mexico City? Or which bus companies serve the route San Diego to Mexico City? Below you will find answers to your questions.

FAQs about the San Diego to Mexico City bus

How much does a San Diego Mexico City bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $222 and takes 62h 15m to reach Mexico City. Compare offers to save money!

How much could I save by comparing buses from San Diego to Mexico City?

This route is offered by 2 companies with a range of ticket prices between $222 and $440. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mexico City.

On average, how many connections are available from San Diego to Mexico City each day?

Every day, the San Diego to Mexico City bus route is served by approximately 13 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to Mexico City take?

The fastest bus from San Diego to Mexico City is offered by Greyhound US and takes 61h 15m. Bus tickets for this connection cost $232. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to Mexico City?

The earliest bus arriving in Mexico City from San Diego starts at 12:15 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to Mexico City?

The latest bus trip departing from San Diego for Mexico City starts at 7:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego Mexico City route?

When traveling by bus from San Diego to Mexico City, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and Mexico City?

You can check all the direct connections between San Diego and Mexico City by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to Mexico City bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego Mexico City bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego Mexico City bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to Mexico City on your planned travel date.

How does CheckMyBus find the best bus deals from San Diego to Mexico City?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 13 daily trips between San Diego and Mexico City. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Diego to Mexico City?

Prices and availability for 13 trips between San Diego and Mexico City change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Diego to Mexico City

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to Mexico City

Here’s an overview of the most popular bus routes to San Diego and to Mexico City. Simply click on the connection of your choice, and you will find all the details about your bus route!