Bus from San Diego to Mexico City from $216

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Compare all timetables for the bus from San Diego to Mexico City

Here is a selection of the cheapest bus trips from the schedule from San Diego to Mexico City from various bus operators like FlixBus or Greyhound US for the next days.

today
$217
tomorrow
$216
Monday
$216
Tuesday
$216
Wednesday
$237
Thursday
$218
Friday
$219

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 61h 30m 7:35 AM San Diego Old Town Transit Center 10:05 PM Mexico City Fórum Buenavista  Economy $217
FlixBus 61h 55m 7:35 AM San Diego Old Town Transit Center 10:30 PM Mexico City San Pedro Santa Clara Bus Stop  Economy $217
FlixBus 67h 0m 9:25 AM San Diego Old Town Transit Center 5:25 AM Mexico City Fórum Buenavista  Economy $219
Greyhound US 64h 40m 7:55 PM San Diego Old Town Transit Center 1:35 PM Mexico City Fórum Buenavista  Economy $219
Greyhound US 65h 5m 7:55 PM San Diego Old Town Transit Center 2:00 PM Mexico City San Pedro Santa Clara Bus Stop  Economy $219
  • Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $91? You can find the corresponding connections below.
    • Greyhound Lines Mexico
      56h 35m
      0
      7:15 PM
      San Diego
      San Ysidro Transit Center
      8:15 PM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      0
      Greyhound Lines Mexico
      Economy
      $8
    • Waiting Time 13h 25m
    • ACN Autobuses
      42h 10m
      0
      9:40 AM
      Tijuana, BC
      Centro Bus Stop
      4:50 AM
      Mexico City
      Calz. Ignacio Zaragoza
      0
      ACN Autobuses
      Economy
      $118
    Travel Time is 5h 55m shorter, and you will save $91

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 61h 55m 7:35 AM San Diego Old Town Transit Center 10:30 PM Mexico City San Pedro Santa Clara Bus Stop  Economy $216
FlixBus 61h 30m 7:35 AM San Diego Old Town Transit Center 10:05 PM Mexico City Fórum Buenavista  Economy $216
Greyhound US 68h 10m 7:55 PM San Diego Old Town Transit Center 5:05 PM Mexico City San Pedro Santa Clara Bus Stop  Economy $218
Greyhound US 67h 45m 7:55 PM San Diego Old Town Transit Center 4:40 PM Mexico City Fórum Buenavista  Economy $218
FlixBus 67h 25m 9:25 AM San Diego Old Town Transit Center 5:50 AM Mexico City San Pedro Santa Clara Bus Stop  Economy $219
  • Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $90? You can find the corresponding connections below.
    • Greyhound Lines Mexico
      56h 35m
      0
      7:15 PM
      San Diego
      San Ysidro Transit Center
      8:15 PM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      0
      Greyhound Lines Mexico
      Economy
      $8
    • Waiting Time 13h 25m
    • ACN Autobuses
      42h 10m
      0
      9:40 AM
      Tijuana, BC
      Centro Bus Stop
      4:50 AM
      Mexico City
      Calz. Ignacio Zaragoza
      0
      ACN Autobuses
      Economy
      $118
    Travel Time is 5h 55m shorter, and you will save $90

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 61h 30m 7:35 AM San Diego Old Town Transit Center 10:05 PM Mexico City Fórum Buenavista  Economy $216
FlixBus 61h 55m 7:35 AM San Diego Old Town Transit Center 10:30 PM Mexico City San Pedro Santa Clara Bus Stop  Economy $216
Greyhound US 73h 10m 7:55 PM San Diego Old Town Transit Center 10:05 PM Mexico City Fórum Buenavista  Economy $218
Greyhound US 73h 35m 7:55 PM San Diego Old Town Transit Center 10:30 PM Mexico City San Pedro Santa Clara Bus Stop  Economy $218
Greyhound US 59h 15m 9:50 AM San Diego Old Town Transit Center 10:05 PM Mexico City Fórum Buenavista  Economy $220
  • Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $90? You can find the corresponding connections below.
    • Greyhound Lines Mexico
      56h 35m
      0
      7:15 PM
      San Diego
      San Ysidro Transit Center
      8:15 PM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      0
      Greyhound Lines Mexico
      Economy
      $8
    • Waiting Time 13h 25m
    • ACN Autobuses
      42h 10m
      0
      9:40 AM
      Tijuana, BC
      Centro Bus Stop
      4:50 AM
      Mexico City
      Calz. Ignacio Zaragoza
      0
      ACN Autobuses
      Economy
      $118
    Travel Time is 3h 40m shorter, and you will save $90

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 61h 30m 7:35 AM San Diego Old Town Transit Center 10:05 PM Mexico City Fórum Buenavista  Economy $216
FlixBus 61h 55m 7:35 AM San Diego Old Town Transit Center 10:30 PM Mexico City San Pedro Santa Clara Bus Stop  Economy $216
Greyhound US 59h 15m 9:50 AM San Diego Old Town Transit Center 10:05 PM Mexico City Fórum Buenavista  Economy $220
Greyhound US 64h 40m 7:55 PM San Diego Old Town Transit Center 1:35 PM Mexico City Fórum Buenavista  Economy $220
Greyhound US 59h 40m 9:50 AM San Diego Old Town Transit Center 10:30 PM Mexico City San Pedro Santa Clara Bus Stop  Economy $220
  • Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $90? You can find the corresponding connections below.
    • Greyhound Lines Mexico
      56h 35m
      0
      7:15 PM
      San Diego
      San Ysidro Transit Center
      8:15 PM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      0
      Greyhound Lines Mexico
      Economy
      $8
    • Waiting Time 13h 25m
    • ACN Autobuses
      42h 10m
      0
      9:40 AM
      Tijuana, BC
      Centro Bus Stop
      4:50 AM
      Mexico City
      Calz. Ignacio Zaragoza
      0
      ACN Autobuses
      Economy
      $118
    Travel Time is 3h 40m shorter, and you will save $90

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 60h 15m 9:15 AM San Diego San Ysidro Transit Center 10:30 PM Mexico City San Pedro Santa Clara Bus Stop  Economy $237
Greyhound US 59h 50m 9:15 AM San Diego San Ysidro Transit Center 10:05 PM Mexico City Fórum Buenavista  Economy $237
FlixBus 63h 45m 12:40 PM San Diego San Ysidro Transit Center 5:25 AM Mexico City Fórum Buenavista  Economy $238
Greyhound US 81h 40m 7:10 PM San Diego San Ysidro Transit Center 5:50 AM Mexico City San Pedro Santa Clara Bus Stop  Economy $256
  • Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $111? You can find the corresponding connections below.
    • Greyhound Lines Mexico
      56h 35m
      0
      7:15 PM
      San Diego
      San Ysidro Transit Center
      8:15 PM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      0
      Greyhound Lines Mexico
      Economy
      $8
    • Waiting Time 13h 25m
    • ACN Autobuses
      42h 10m
      0
      9:40 AM
      Tijuana, BC
      Centro Bus Stop
      4:50 AM
      Mexico City
      Calz. Ignacio Zaragoza
      0
      ACN Autobuses
      Economy
      $118
    Travel Time is 4h 15m shorter, and you will save $111

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 61h 30m 7:35 AM San Diego Old Town Transit Center 10:05 PM Mexico City Fórum Buenavista  Economy $218
FlixBus 67h 0m 9:25 AM San Diego Old Town Transit Center 5:25 AM Mexico City Fórum Buenavista  Economy $219
FlixBus 67h 25m 9:25 AM San Diego Old Town Transit Center 5:50 AM Mexico City San Pedro Santa Clara Bus Stop  Economy $219
Greyhound US 59h 15m 9:50 AM San Diego Old Town Transit Center 10:05 PM Mexico City Fórum Buenavista  Economy $220
Greyhound US 67h 0m 9:50 AM San Diego Old Town Transit Center 5:50 AM Mexico City San Pedro Santa Clara Bus Stop  Economy $220
  • Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $92? You can find the corresponding connections below.
    • Greyhound Lines Mexico
      56h 35m
      0
      7:15 PM
      San Diego
      San Ysidro Transit Center
      8:15 PM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      0
      Greyhound Lines Mexico
      Economy
      $8
    • Waiting Time 13h 25m
    • ACN Autobuses
      42h 10m
      0
      9:40 AM
      Tijuana, BC
      Centro Bus Stop
      4:50 AM
      Mexico City
      Calz. Ignacio Zaragoza
      0
      ACN Autobuses
      Economy
      $118
    Travel Time is 3h 40m shorter, and you will save $92

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 67h 25m 9:25 AM San Diego Old Town Transit Center 5:50 AM Mexico City San Pedro Santa Clara Bus Stop  Economy $219
FlixBus 67h 0m 9:25 AM San Diego Old Town Transit Center 5:25 AM Mexico City Fórum Buenavista  Economy $219
FlixBus 63h 40m 1:10 PM San Diego Seaport Village 5:50 AM Mexico City San Pedro Santa Clara Bus Stop  Economy $220
Greyhound US 59h 40m 9:50 AM San Diego Old Town Transit Center 10:30 PM Mexico City San Pedro Santa Clara Bus Stop  Economy $223
Greyhound US 59h 15m 9:50 AM San Diego Old Town Transit Center 10:05 PM Mexico City Fórum Buenavista  Economy $223
  • Did you know that if you travel from San Diego to Mexico City via Tijuana, BC, you can save more than $93? You can find the corresponding connections below.
    • Greyhound Lines Mexico
      56h 35m
      0
      7:15 PM
      San Diego
      San Ysidro Transit Center
      8:15 PM
      Tijuana, BC
      Cross Border Xpress CBX Bus Station
      0
      Greyhound Lines Mexico
      Economy
      $8
    • Waiting Time 13h 25m
    • ACN Autobuses
      42h 10m
      0
      9:40 AM
      Tijuana, BC
      Centro Bus Stop
      4:50 AM
      Mexico City
      Calz. Ignacio Zaragoza
      0
      ACN Autobuses
      Economy
      $118
    Travel Time is 3h 40m shorter, and you will save $93

Best Price Offer: The price for the cheapest bus from San Diego to Mexico City is $216 on 6/21/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between San Diego and Mexico City

See here how frequent the connections between San Diego and Mexico City are, during different times and days of the week.
Sunday is the busiest day, with more than 16 daily buses from San Diego to Mexico City. Wednesday has instead the fewest connections, with only 5 daily coaches between San Diego and Mexico City.
The busiest time of the day is the Morning, with 45 buses from San Diego to Mexico City, while Afternoon sees the fewest connections between San Diego and Mexico City, with 21 offers.

Facts about the bus from San Diego to Mexico City

Compare all providers like FlixBus and Greyhound US that travel 12 times every day by bus from San Diego to Mexico City in one click! Book your bus ticket from San Diego to Mexico City starting from $216!

Cheapest Bus $216
Fastest Bus 60h 15m
Earliest Bus 7:35 AM
Latest Bus 7:55 PM
Daily Bus Routes 12 Ø
Distance 1,443.3 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from San Diego to Mexico City

Every day, 12 buses from 2 bus companies leave San Diego for Mexico City: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/20/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/14
Monday 06/15
Tuesday 06/16
Wednesday 06/17
Thursday 06/18
Friday 06/19
Saturday 06/20
$232
Sunday 06/21
$255
Monday 06/22
$236
Tuesday 06/23
$232
Wednesday 06/24
$237
Thursday 06/25
$218
Friday 06/26
$219
Saturday 06/27
$223
Sunday 06/28
$222
Monday 06/29
Tuesday 06/30
$226
Wednesday 07/01
$229
Thursday 07/02
$221
Friday 07/03
$223
Saturday 07/04
Sunday 07/05
Monday 07/06
$225
Tuesday 07/07
$223
Wednesday 07/08
$223
Thursday 07/09
$223
Friday 07/10
$218
Saturday 07/11

The cheapest time to travel from San Diego to Mexico City

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to Mexico City, for the next 30 days.
With a price starting from $216, Sunday is the cheapest day for a bus from San Diego to Mexico City. Wednesday instead is the most expensive day with prices starting from $222.
Morning is the cheapest day time for bus tickets from San Diego to Mexico City, with $216. Afternoon is the most expensive time of the day with prices starting from $220.

How to save money travelling from San Diego to Mexico City

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to Mexico City in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to Mexico City, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to Mexico City are also emptier.

All bus stations and stops in San Diego and Mexico City

In the map below, you can see where to find all bus stations in San Diego and Mexico City.

Service and Comfort on the bus from San Diego to Mexico City

Want to know which seat classes are available on the buses from San Diego to Mexico City? Or which bus companies serve the route San Diego to Mexico City? Below you will find answers to your questions.

FAQs about the San Diego to Mexico City bus

How much does a San Diego Mexico City bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $216 and takes 62h 55m to reach Mexico City. Compare offers to save money!

How much could I save by comparing buses from San Diego to Mexico City?

This route is offered by 2 companies with a range of ticket prices between $216 and $448. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mexico City.

On average, how many connections are available from San Diego to Mexico City each day?

Every day, the San Diego to Mexico City bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to Mexico City take?

The fastest bus from San Diego to Mexico City is offered by Greyhound US and takes 60h 15m. Bus tickets for this connection cost $221. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to Mexico City?

The earliest bus arriving in Mexico City from San Diego starts at 7:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to Mexico City?

The latest bus trip departing from San Diego for Mexico City starts at 7:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego Mexico City route?

When traveling by bus from San Diego to Mexico City, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and Mexico City?

You can check all the direct connections between San Diego and Mexico City by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to Mexico City bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego Mexico City bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego Mexico City bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to Mexico City on your planned travel date.

How does CheckMyBus find the best bus deals from San Diego to Mexico City?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 12 daily trips between San Diego and Mexico City. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Diego to Mexico City?

Prices and availability for 12 trips between San Diego and Mexico City change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Diego to Mexico City

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to Mexico City

Here’s an overview of the most popular bus routes to San Diego and to Mexico City. Simply click on the connection of your choice, and you will find all the details about your bus route!

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