Bus San Luis Potosí to Mexico City: Compare prices and save money

Compare all timetables for the bus from San Luis Potosí to Mexico City

Here is a selection of the cheapest bus trips from the schedule from San Luis Potosí to Mexico City from various bus operators like Futura, Flix Mexico or Senda TDN Diamante for the next days.

today

$27

tomorrow

$27

Monday

$27

Tuesday

$27

Wednesday

$27

Thursday

$27

Friday

$27

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viajes Seguro	5h 0m	6:00 PM	San Luis Potosí	Central Bus Station	11:00 PM	Mexico City	Parque Delta Bus Station	Economy	$27	A Bus from Viajes Seguro goes from Central Bus Station, San Luis Potosí (Mexico) at 4/18/2026 6:00:00 PM to Parque Delta Bus Station, Mexico City (Mexico) arriving at 4/18/2026 11:00:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 0m
Flix Mexico	6h 40m	3:25 PM	San Luis Potosí	Soriana El Paseo Bus Station	10:05 PM	Mexico City	Fórum Buenavista	Economy	$28	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/18/2026 3:25:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 4/18/2026 10:05:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 40m
Valle del Guadiana	5h 38m	10:08 PM	San Luis Potosí	Central Bus Station	3:46 AM	Mexico City	Eje Central Bus Stop	Economy	$48	A Bus from Valle del Guadiana goes from Central Bus Station, San Luis Potosí (Mexico) at 4/18/2026 10:08:00 PM to Eje Central Bus Stop, Mexico City (Mexico) arriving at 4/19/2026 3:46:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 38m
Senda TDN Diamante	6h 1m	6:20 AM	San Luis Potosí	Central Bus Station	12:21 PM	Mexico City	Norte Bus Station	Basic	$53	A Bus from Senda TDN Diamante goes from Central Bus Station, San Luis Potosí (Mexico) at 4/18/2026 6:20:00 AM to Norte Bus Station, Mexico City (Mexico) arriving at 4/18/2026 12:21:00 PM. 50 Basic ticket for $53 per person are available. Travel duration is 6h 1m
Futura	6h 40m	1:20 PM	San Luis Potosí	Central Bus Station	8:00 PM	Mexico City	Norte Bus Station	Economy	$55	A Bus from Futura goes from Central Bus Station, San Luis Potosí (Mexico) at 4/18/2026 1:20:00 PM to Norte Bus Station, Mexico City (Mexico) arriving at 4/18/2026 8:00:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 6h 40m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viajes Seguro	5h 0m	5:00 PM	San Luis Potosí	Central Bus Station	10:00 PM	Mexico City	Parque Delta Bus Station	Economy	$27	A Bus from Viajes Seguro goes from Central Bus Station, San Luis Potosí (Mexico) at 4/19/2026 5:00:00 PM to Parque Delta Bus Station, Mexico City (Mexico) arriving at 4/19/2026 10:00:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 0m
Flix Mexico	6h 5m	5:45 PM	San Luis Potosí	Soriana El Paseo Bus Station	11:50 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$28	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/19/2026 5:45:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 4/19/2026 11:50:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 5m
SKPT de Viaje	6h 30m	11:30 PM	San Luis Potosí	Central Bus Station	6:00 AM	Mexico City	Norte Bus Station	Premium Economy	$29	A Bus from SKPT de Viaje goes from Central Bus Station, San Luis Potosí (Mexico) at 4/19/2026 11:30:00 PM to Norte Bus Station, Mexico City (Mexico) arriving at 4/20/2026 6:00:00 AM. 50 Premium Economy ticket for $29 per person are available. Travel duration is 6h 30m
Primera Plus	5h 0m	1:00 AM	San Luis Potosí	Central Bus Station	6:00 AM	Mexico City	Norte Bus Station	Economy	$42	A Bus from Primera Plus goes from Central Bus Station, San Luis Potosí (Mexico) at 4/19/2026 1:00:00 AM to Norte Bus Station, Mexico City (Mexico) arriving at 4/19/2026 6:00:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 0m
Valle del Guadiana	5h 38m	6:00 AM	San Luis Potosí	Central Bus Station	11:38 AM	Mexico City	Eje Central Bus Stop	Economy	$48	A Bus from Valle del Guadiana goes from Central Bus Station, San Luis Potosí (Mexico) at 4/19/2026 6:00:00 AM to Eje Central Bus Stop, Mexico City (Mexico) arriving at 4/19/2026 11:38:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 38m

Did you know that if you travel from San Luis Potosí to Mexico City via Santiago de Queretaro, you can save more than $3? You can find the corresponding connections below.
- Flix Mexico
  
  5h 40m
  
  0
  
  5:45 PM
  
  San Luis Potosí
  Soriana El Paseo Bus Station
  
  8:30 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $10
  
  A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/20/2026 5:45:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/20/2026 8:30:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 2h 45m
- Flix Mexico
  
  2h 45m
  
  0
  
  8:40 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  11:25 PM
  
  Mexico City
  Fórum Buenavista
  
  0
  
  Economy
  
  $14
  
  A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/20/2026 8:40:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 4/20/2026 11:25:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 2h 45m
Travel time is 0h 40m longer, but you will save $3

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viajes Seguro	5h 0m	6:00 PM	San Luis Potosí	Central Bus Station	11:00 PM	Mexico City	Parque Delta Bus Station	Economy	$27	A Bus from Viajes Seguro goes from Central Bus Station, San Luis Potosí (Mexico) at 4/20/2026 6:00:00 PM to Parque Delta Bus Station, Mexico City (Mexico) arriving at 4/20/2026 11:00:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 0m
Flix Mexico	6h 40m	7:20 AM	San Luis Potosí	Soriana El Paseo Bus Station	2:00 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$28	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/20/2026 7:20:00 AM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 4/20/2026 2:00:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 40m
Primera Plus	5h 0m	1:00 AM	San Luis Potosí	Central Bus Station	6:00 AM	Mexico City	Norte Bus Station	Economy	$38	A Bus from Primera Plus goes from Central Bus Station, San Luis Potosí (Mexico) at 4/20/2026 1:00:00 AM to Norte Bus Station, Mexico City (Mexico) arriving at 4/20/2026 6:00:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 5h 0m
Valle del Guadiana	5h 38m	6:00 AM	San Luis Potosí	Central Bus Station	11:38 AM	Mexico City	Eje Central Bus Stop	Economy	$48	A Bus from Valle del Guadiana goes from Central Bus Station, San Luis Potosí (Mexico) at 4/20/2026 6:00:00 AM to Eje Central Bus Stop, Mexico City (Mexico) arriving at 4/20/2026 11:38:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 38m
Senda TDN Diamante	6h 1m	12:09 AM	San Luis Potosí	Central Bus Station	6:10 AM	Mexico City	Norte Bus Station	Basic	$54	A Bus from Senda TDN Diamante goes from Central Bus Station, San Luis Potosí (Mexico) at 4/20/2026 12:09:00 AM to Norte Bus Station, Mexico City (Mexico) arriving at 4/20/2026 6:10:00 AM. 50 Basic ticket for $54 per person are available. Travel duration is 6h 1m

Did you know that if you travel from San Luis Potosí to Mexico City via Santiago de Queretaro, you can save more than $5? You can find the corresponding connections below.
- Flix Mexico
  
  6h 40m
  
  0
  
  3:25 PM
  
  San Luis Potosí
  Soriana El Paseo Bus Station
  
  6:40 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $10
  
  A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/21/2026 3:25:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/21/2026 6:40:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 3h 15m
- Flix Mexico
  
  3h 15m
  
  0
  
  6:50 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  10:05 PM
  
  Mexico City
  Fórum Buenavista
  
  0
  
  Economy
  
  $12
  
  A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/21/2026 6:50:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 4/21/2026 10:05:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 15m
Travel time is 1h 40m longer, but you will save $5

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viajes Seguro	5h 0m	6:00 PM	San Luis Potosí	Central Bus Station	11:00 PM	Mexico City	Parque Delta Bus Station	Economy	$27	A Bus from Viajes Seguro goes from Central Bus Station, San Luis Potosí (Mexico) at 4/21/2026 6:00:00 PM to Parque Delta Bus Station, Mexico City (Mexico) arriving at 4/21/2026 11:00:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 0m
Flix Mexico	6h 45m	3:00 AM	San Luis Potosí	Soriana El Paseo Bus Station	9:45 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$28	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/21/2026 3:00:00 AM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 4/21/2026 9:45:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 45m
Primera Plus	5h 0m	1:00 AM	San Luis Potosí	Central Bus Station	6:00 AM	Mexico City	Norte Bus Station	Economy	$42	A Bus from Primera Plus goes from Central Bus Station, San Luis Potosí (Mexico) at 4/21/2026 1:00:00 AM to Norte Bus Station, Mexico City (Mexico) arriving at 4/21/2026 6:00:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 0m
Valle del Guadiana	5h 38m	6:00 AM	San Luis Potosí	Central Bus Station	11:38 AM	Mexico City	Eje Central Bus Stop	Economy	$48	A Bus from Valle del Guadiana goes from Central Bus Station, San Luis Potosí (Mexico) at 4/21/2026 6:00:00 AM to Eje Central Bus Stop, Mexico City (Mexico) arriving at 4/21/2026 11:38:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 38m
Senda TDN Diamante	6h 1m	12:09 AM	San Luis Potosí	Central Bus Station	6:10 AM	Mexico City	Norte Bus Station	Basic	$54	A Bus from Senda TDN Diamante goes from Central Bus Station, San Luis Potosí (Mexico) at 4/21/2026 12:09:00 AM to Norte Bus Station, Mexico City (Mexico) arriving at 4/21/2026 6:10:00 AM. 50 Basic ticket for $54 per person are available. Travel duration is 6h 1m

Did you know that if you travel from San Luis Potosí to Mexico City via Santiago de Queretaro, you can save more than $6? You can find the corresponding connections below.
- Flix Mexico
  
  6h 15m
  
  0
  
  5:00 PM
  
  San Luis Potosí
  Soriana El Paseo Bus Station
  
  7:55 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $9
  
  A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/22/2026 5:00:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/22/2026 7:55:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 55m
- Flix Mexico
  
  3h 0m
  
  0
  
  8:15 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  11:15 PM
  
  Mexico City
  Fórum Buenavista
  
  0
  
  Economy
  
  $12
  
  A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/22/2026 8:15:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 4/22/2026 11:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 0m
Travel time is 1h 15m longer, but you will save $6

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viajes Seguro	5h 0m	6:00 PM	San Luis Potosí	Central Bus Station	11:00 PM	Mexico City	Parque Delta Bus Station	Economy	$27	A Bus from Viajes Seguro goes from Central Bus Station, San Luis Potosí (Mexico) at 4/22/2026 6:00:00 PM to Parque Delta Bus Station, Mexico City (Mexico) arriving at 4/22/2026 11:00:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 0m
Flix Mexico	7h 5m	3:25 PM	San Luis Potosí	Soriana El Paseo Bus Station	10:30 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$28	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/22/2026 3:25:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 4/22/2026 10:30:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 7h 5m
Primera Plus	5h 0m	1:00 AM	San Luis Potosí	Central Bus Station	6:00 AM	Mexico City	Norte Bus Station	Economy	$42	A Bus from Primera Plus goes from Central Bus Station, San Luis Potosí (Mexico) at 4/22/2026 1:00:00 AM to Norte Bus Station, Mexico City (Mexico) arriving at 4/22/2026 6:00:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 0m
Valle del Guadiana	5h 38m	6:00 AM	San Luis Potosí	Central Bus Station	11:38 AM	Mexico City	Eje Central Bus Stop	Economy	$48	A Bus from Valle del Guadiana goes from Central Bus Station, San Luis Potosí (Mexico) at 4/22/2026 6:00:00 AM to Eje Central Bus Stop, Mexico City (Mexico) arriving at 4/22/2026 11:38:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 38m
Futura	6h 40m	1:20 PM	San Luis Potosí	Central Bus Station	8:00 PM	Mexico City	Norte Bus Station	Economy	$55	A Bus from Futura goes from Central Bus Station, San Luis Potosí (Mexico) at 4/22/2026 1:20:00 PM to Norte Bus Station, Mexico City (Mexico) arriving at 4/22/2026 8:00:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 6h 40m

Did you know that if you travel from San Luis Potosí to Mexico City via Santiago de Queretaro, you can save more than $6? You can find the corresponding connections below.
- Flix Mexico
  
  6h 15m
  
  0
  
  5:00 PM
  
  San Luis Potosí
  Soriana El Paseo Bus Station
  
  7:55 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $9
  
  A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/22/2026 5:00:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/22/2026 7:55:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 55m
- Flix Mexico
  
  3h 0m
  
  0
  
  8:15 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  11:15 PM
  
  Mexico City
  Fórum Buenavista
  
  0
  
  Economy
  
  $12
  
  A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/22/2026 8:15:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 4/22/2026 11:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 0m
Travel time is 1h 15m longer, but you will save $6

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viajes Seguro	5h 0m	6:00 PM	San Luis Potosí	Central Bus Station	11:00 PM	Mexico City	Parque Delta Bus Station	Economy	$27	A Bus from Viajes Seguro goes from Central Bus Station, San Luis Potosí (Mexico) at 4/23/2026 6:00:00 PM to Parque Delta Bus Station, Mexico City (Mexico) arriving at 4/23/2026 11:00:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 0m
Flix Mexico	6h 45m	3:00 AM	San Luis Potosí	Soriana El Paseo Bus Station	9:45 AM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$28	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/23/2026 3:00:00 AM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 4/23/2026 9:45:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 45m
Primera Plus	5h 0m	1:00 AM	San Luis Potosí	Central Bus Station	6:00 AM	Mexico City	Norte Bus Station	Economy	$42	A Bus from Primera Plus goes from Central Bus Station, San Luis Potosí (Mexico) at 4/23/2026 1:00:00 AM to Norte Bus Station, Mexico City (Mexico) arriving at 4/23/2026 6:00:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 0m
Valle del Guadiana	5h 38m	6:00 AM	San Luis Potosí	Central Bus Station	11:38 AM	Mexico City	Eje Central Bus Stop	Economy	$48	A Bus from Valle del Guadiana goes from Central Bus Station, San Luis Potosí (Mexico) at 4/23/2026 6:00:00 AM to Eje Central Bus Stop, Mexico City (Mexico) arriving at 4/23/2026 11:38:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 38m
Futura	6h 0m	12:50 AM	San Luis Potosí	Central Bus Station	6:50 AM	Mexico City	Taxqueña Bus Station	Economy	$54	A Bus from Futura goes from Central Bus Station, San Luis Potosí (Mexico) at 4/23/2026 12:50:00 AM to Taxqueña Bus Station, Mexico City (Mexico) arriving at 4/23/2026 6:50:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 6h 0m

Did you know that if you travel from San Luis Potosí to Mexico City via Santiago de Queretaro, you can save more than $6? You can find the corresponding connections below.
- Flix Mexico
  
  6h 15m
  
  0
  
  5:00 PM
  
  San Luis Potosí
  Soriana El Paseo Bus Station
  
  7:55 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $9
  
  A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/22/2026 5:00:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/22/2026 7:55:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 55m
- Flix Mexico
  
  3h 0m
  
  0
  
  8:15 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  11:15 PM
  
  Mexico City
  Fórum Buenavista
  
  0
  
  Economy
  
  $12
  
  A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/22/2026 8:15:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 4/22/2026 11:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 0m
Travel time is 1h 15m longer, but you will save $6

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Viajes Seguro	5h 0m	6:00 PM	San Luis Potosí	Central Bus Station	11:00 PM	Mexico City	Parque Delta Bus Station	Economy	$27	A Bus from Viajes Seguro goes from Central Bus Station, San Luis Potosí (Mexico) at 4/24/2026 6:00:00 PM to Parque Delta Bus Station, Mexico City (Mexico) arriving at 4/24/2026 11:00:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 0m
SKPT de Viaje	6h 30m	11:30 PM	San Luis Potosí	Central Bus Station	6:00 AM	Mexico City	Norte Bus Station	Premium Economy	$29	A Bus from SKPT de Viaje goes from Central Bus Station, San Luis Potosí (Mexico) at 4/24/2026 11:30:00 PM to Norte Bus Station, Mexico City (Mexico) arriving at 4/25/2026 6:00:00 AM. 50 Premium Economy ticket for $29 per person are available. Travel duration is 6h 30m
Flix Mexico	7h 5m	3:25 PM	San Luis Potosí	Soriana El Paseo Bus Station	10:30 PM	Mexico City	San Pedro Santa Clara Bus Stop	Economy	$31	A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/24/2026 3:25:00 PM to San Pedro Santa Clara Bus Stop, Mexico City (Mexico) arriving at 4/24/2026 10:30:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 7h 5m
Valle del Guadiana	5h 38m	6:00 AM	San Luis Potosí	Central Bus Station	11:38 AM	Mexico City	Eje Central Bus Stop	Economy	$48	A Bus from Valle del Guadiana goes from Central Bus Station, San Luis Potosí (Mexico) at 4/24/2026 6:00:00 AM to Eje Central Bus Stop, Mexico City (Mexico) arriving at 4/24/2026 11:38:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 38m
Senda TDN Diamante	6h 1m	12:09 AM	San Luis Potosí	Central Bus Station	6:10 AM	Mexico City	Norte Bus Station	Basic	$52	A Bus from Senda TDN Diamante goes from Central Bus Station, San Luis Potosí (Mexico) at 4/24/2026 12:09:00 AM to Norte Bus Station, Mexico City (Mexico) arriving at 4/24/2026 6:10:00 AM. 50 Basic ticket for $52 per person are available. Travel duration is 6h 1m

Did you know that if you travel from San Luis Potosí to Mexico City via Santiago de Queretaro, you can save more than $6? You can find the corresponding connections below.
- Flix Mexico
  
  6h 15m
  
  0
  
  5:00 PM
  
  San Luis Potosí
  Soriana El Paseo Bus Station
  
  7:55 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  0
  
  Economy
  
  $9
  
  A Bus from Flix Mexico goes from Soriana El Paseo Bus Station, San Luis Potosí (Mexico) at 4/22/2026 5:00:00 PM to Centro Comercial Galeria, Santiago de Queretaro (Mexico) arriving at 4/22/2026 7:55:00 PM. 50 Economy ticket for $9 per person are available. Travel duration is 2h 55m
- Flix Mexico
  
  3h 0m
  
  0
  
  8:15 PM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  11:15 PM
  
  Mexico City
  Fórum Buenavista
  
  0
  
  Economy
  
  $12
  
  A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/22/2026 8:15:00 PM to Fórum Buenavista, Mexico City (Mexico) arriving at 4/22/2026 11:15:00 PM. 50 Economy ticket for $12 per person are available. Travel duration is 3h 0m
Travel time is 1h 15m longer, but you will save $6

Best Price Offer: The price for the cheapest bus from San Luis Potosí to Mexico City is $11 on 4/13/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Luis Potosí and Mexico City

See here how frequent the connections between San Luis Potosí and Mexico City are, during different times and days of the week.

Monday is the busiest day, with more than 142 daily buses from San Luis Potosí to Mexico City. Saturday has instead the fewest connections, with only 64 daily coaches between San Luis Potosí and Mexico City.

The busiest time of the day is the Afternoon, with 200 buses from San Luis Potosí to Mexico City, while Morning sees the fewest connections between San Luis Potosí and Mexico City, with 172 offers.

Facts about the bus from San Luis Potosí to Mexico City

Compare all providers like Futura, Flix Mexico and Senda TDN Diamante that travel 107 times every day by bus from San Luis Potosí to Mexico City in one click! Book your bus ticket from San Luis Potosí to Mexico City starting from $11!

Cheapest Bus	$11
Fastest Bus	4h 45m
Earliest Bus	5:45 AM
Latest Bus	11:59 PM
Daily Bus Routes	107 Ø
Distance	221.3 miles
Bus Companies	Futura, Flix Mexico, Senda TDN Diamante, Primera Plus, ETN Autobuses, Transportes Chihuahuenses, Viajes Seguro, Autobuses Anáhuac, Valle del Guadiana, Turistar and 1 more.

Cheapest bus connections from San Luis Potosí to Mexico City

Every day, 107 buses from 11 bus companies leave San Luis Potosí for Mexico City: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/18/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/12

Monday 04/13

Tuesday 04/14

Wednesday 04/15

Thursday 04/16

Friday 04/17

Saturday 04/18

$11

Sunday 04/19

$65

Monday 04/20

$27

Tuesday 04/21

$29

Wednesday 04/22

$27

Thursday 04/23

$55

Friday 04/24

$55

Saturday 04/25

$11

Sunday 04/26

$55

Monday 04/27

$27

Tuesday 04/28

$55

Wednesday 04/29

$60

Thursday 04/30

$60

Friday 05/01

$55

Saturday 05/02

$54

Sunday 05/03

$55

Monday 05/04

$11

Tuesday 05/05

$27

Wednesday 05/06

$55

Thursday 05/07

$54

Friday 05/08

$11

Saturday 05/09

The cheapest time to travel from San Luis Potosí to Mexico City

See here on which day and which time of the day you can find the cheapest bus ticket from San Luis Potosí to Mexico City, for the next 30 days.

With a price starting from $11, Thursday is the cheapest day for a bus from San Luis Potosí to Mexico City. Sunday instead is the most expensive day with prices starting from $27.

Night is the cheapest day time for bus tickets from San Luis Potosí to Mexico City, with $11. Morning is the most expensive time of the day with prices starting from $28.

How to save money travelling from San Luis Potosí to Mexico City

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Luis Potosí to Mexico City in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Luis Potosí to Mexico City, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Luis Potosí to Mexico City are also emptier.

Beloved bus companies from San Luis Potosí to Mexico City

These are the most booked bus companies between San Luis Potosí to Mexico City from our users.

Futura from San Luis Potosí to Mexico City

Here you will find the key facts about the Futura bus route San Luis Potosí to Mexico City:

Cheapest Price	$34
Fastest Bus	4h 45m
Earliest Bus	5:45 AM
Last Bus	11:59 PM
Daily Connections	64 Ø
Found on	4/18/2026

Transportes Frontera from San Luis Potosí to Mexico City

Here you will find the key facts about the Transportes Frontera bus route San Luis Potosí to Mexico City:

Cheapest Price	$30
Fastest Bus	5h 35m
Earliest Bus	10:15 PM
Last Bus	10:15 PM
Daily Connections	1 Ø
Found on	4/2/2026

Senda TDN Diamante from San Luis Potosí to Mexico City

Here you will find the key facts about the Senda TDN Diamante bus route San Luis Potosí to Mexico City:

Cheapest Price	$52
Fastest Bus	5h 55m
Earliest Bus	6:20 AM
Last Bus	12:35 PM
Daily Connections	13 Ø
Found on	4/18/2026

Latest reviews for bus companies on the route San Luis Potosí - Mexico City

Luna, 3/14/2025

Nuestro camion se atraso 3 horas y no nos quisieron dar cancelacion, lo unico que nos ofrecieron fue un cambio pero nos cobrar 250 pesos adicionales!! Apesar de estar en los haciendos de hasta el fren ... Nuestro camion se atraso 3 horas y no nos quisieron dar cancelacion, lo unico que nos ofrecieron fue un cambio pero nos cobrar 250 pesos adicionales!! Apesar de estar en los haciendos de hasta el frente, despues de 3 horas empezo a oler el baño horrible No vale lo que fue el precio, primera y ultima vez viajando con Senda

karla diaz, 1/15/2025

Bajaron a una gatita en medio de la nada sin avisar nada a la dueña y la abandonaron, regrésenla a su familia!!!

All bus stations and stops in San Luis Potosí and Mexico City

In the map below, you can see where to find all bus stations in San Luis Potosí and Mexico City.

Central Bus Station

Av Benito Juarez 250

Soriana El Paseo Bus Station

Doctor Salvador Nava Martínez 405

Av Constitución / Manual José Othón Bus Stop

Avenida Constitución 300

Barrio de Santiago

Bus Stop

Observatorio Central Bus Station

Av Río de Tacubaya 122 232

Eje Central Bus Stop

Avenida Lázaro Cárdenas & Calle Poniente 112 Avenida Lázaro Cárdenas & Calle Poniente 112

Moctezuma Bus Stop

Ampliación 7 de Julio

Terminal Antas Tla

Emiliano Zapata 97

Tlalpan - Metro General Anaya Bus Stop

General Anaya General Anaya

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from San Luis Potosí to Mexico City? Compare all modes of transports from San Luis Potosí to Mexico City.

Service and Comfort on the bus from San Luis Potosí to Mexico City

Want to know which seat classes are available on the buses from San Luis Potosí to Mexico City? Or which bus companies serve the route San Luis Potosí to Mexico City? Below you will find answers to your questions.

FAQs about the San Luis Potosí to Mexico City bus

How much does a San Luis Potosí Mexico City bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $11 and takes 5h 0m to reach Mexico City. Compare offers to save money!

How much could I save by comparing buses from San Luis Potosí to Mexico City?

This route is offered by 11 companies with a range of ticket prices between $11 and $78. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mexico City.

On average, how many connections are available from San Luis Potosí to Mexico City each day?

Every day, the San Luis Potosí to Mexico City bus route is served by approximately 107 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Luis Potosí to Mexico City take?

The fastest bus from San Luis Potosí to Mexico City is offered by Futura and takes 4h 45m. Bus tickets for this connection cost $60. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Luis Potosí to Mexico City?

The earliest bus arriving in Mexico City from San Luis Potosí starts at 5:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Luis Potosí to Mexico City?

The latest bus trip departing from San Luis Potosí for Mexico City starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Luis Potosí Mexico City route?

When traveling by bus from San Luis Potosí to Mexico City, passengers can travel with Futura, Flix Mexico and Senda TDN Diamante. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Luis Potosí and Mexico City?

You can check all the direct connections between San Luis Potosí and Mexico City by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Futura, Flix Mexico and Senda TDN Diamante.

What can I take with me on the San Luis Potosí to Mexico City bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Luis Potosí Mexico City bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Luis Potosí Mexico City bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Luis Potosí to Mexico City on your planned travel date.

How does CheckMyBus find the best bus deals from San Luis Potosí to Mexico City?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 107 daily trips between San Luis Potosí and Mexico City. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Luis Potosí to Mexico City?

Prices and availability for 107 trips between San Luis Potosí and Mexico City change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Luis Potosí to Mexico City

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to San Luis Potosí and to Mexico City

Here’s an overview of the most popular bus routes to San Luis Potosí and to Mexico City. Simply click on the connection of your choice, and you will find all the details about your bus route!