Bus from Mezcales to Mexico City from $110

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Mezcales to Mexico City

Here is a selection of the cheapest bus trips from the schedule from Mezcales to Mexico City from various bus operators like Futura, Primera Plus or ETN Autobuses for the next days.

today
$110
tomorrow
$110
Thursday
$110
Friday
$110
Saturday
$110
Sunday
$110
Monday
$110

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $110
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $110
Futura 13h 15m 11:45 AM Mezcales Primera Plus 1:00 AM Mexico City Terminal del Sur  Economy $111
Futura 14h 35m 6:25 PM Mezcales Primera Plus 9:00 AM Mexico City Terminal del Sur  Economy $111
ETN Autobuses 11h 25m 7:50 PM Mezcales Vallarte Plus 7:15 AM Mexico City Norte Bus Station  Basic $156
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $24? You can find the corresponding connections below.
    • Primera Plus
      13h 40m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $52
      • Waiting Time 0h 40m
    • SKPT de Viaje
      8h 30m
      0
      9:00 PM
      Guadalajara, JC
      Avenida de las Torres Bus Station
      5:30 AM
      Mexico City
      Norte Bus Station
      0
      SKPT de Viaje
      Premium Economy
      $34
    Travel time is 3h 25m longer, but you will save $24

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $110
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $110
Futura 13h 15m 11:45 AM Mezcales Primera Plus 1:00 AM Mexico City Terminal del Sur  Economy $111
Futura 14h 35m 6:25 PM Mezcales Primera Plus 9:00 AM Mexico City Terminal del Sur  Economy $111
ETN Autobuses 11h 25m 7:50 PM Mezcales Vallarte Plus 7:15 AM Mexico City Norte Bus Station  Economy $156
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $24? You can find the corresponding connections below.
    • Primera Plus
      13h 40m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $52
      • Waiting Time 0h 40m
    • SKPT de Viaje
      8h 30m
      0
      9:00 PM
      Guadalajara, JC
      Avenida de las Torres Bus Station
      5:30 AM
      Mexico City
      Norte Bus Station
      0
      SKPT de Viaje
      Premium Economy
      $34
    Travel time is 3h 25m longer, but you will save $24

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $110
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $110
Futura 13h 15m 11:45 AM Mezcales Primera Plus 1:00 AM Mexico City Terminal del Sur  Economy $111
Futura 14h 35m 6:25 PM Mezcales Primera Plus 9:00 AM Mexico City Terminal del Sur  Economy $111
ETN Autobuses 11h 25m 7:50 PM Mezcales Vallarte Plus 7:15 AM Mexico City Norte Bus Station  Basic $156
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $24? You can find the corresponding connections below.
    • Primera Plus
      13h 40m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $52
      • Waiting Time 0h 40m
    • SKPT de Viaje
      8h 30m
      0
      9:00 PM
      Guadalajara, JC
      Avenida de las Torres Bus Station
      5:30 AM
      Mexico City
      Norte Bus Station
      0
      SKPT de Viaje
      Premium Economy
      $34
    Travel time is 3h 25m longer, but you will save $24

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $110
Futura 13h 15m 11:45 AM Mezcales Primera Plus 1:00 AM Mexico City Terminal del Sur  Economy $111
ETN Autobuses 11h 25m 7:50 PM Mezcales Vallarte Plus 7:15 AM Mexico City Norte Bus Station  Basic $156
Transportes Chihuahuenses 33h 0m 12:15 PM Mezcales Primera Plus 9:15 PM Mexico City Eje Central Bus Stop  Economy $195
Elite 39h 20m 7:00 PM Mezcales Primera Plus 10:20 AM Mexico City Eje Central Bus Stop  Economy $195
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $24? You can find the corresponding connections below.
    • Primera Plus
      13h 40m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $52
      • Waiting Time 0h 40m
    • SKPT de Viaje
      8h 30m
      0
      9:00 PM
      Guadalajara, JC
      Avenida de las Torres Bus Station
      5:30 AM
      Mexico City
      Norte Bus Station
      0
      SKPT de Viaje
      Premium Economy
      $34
    Travel time is 3h 20m longer, but you will save $24

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $110
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $110
Futura 13h 15m 11:45 AM Mezcales Primera Plus 1:00 AM Mexico City Terminal del Sur  Economy $111
Futura 14h 35m 6:25 PM Mezcales Primera Plus 9:00 AM Mexico City Terminal del Sur  Economy $111
Futura 14h 35m 1:45 PM Mezcales Primera Plus 4:20 AM Mexico City Norte Bus Station  Economy $118
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $24? You can find the corresponding connections below.
    • Primera Plus
      13h 40m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $52
      • Waiting Time 0h 40m
    • SKPT de Viaje
      8h 30m
      0
      9:00 PM
      Guadalajara, JC
      Avenida de las Torres Bus Station
      5:30 AM
      Mexico City
      Norte Bus Station
      0
      SKPT de Viaje
      Premium Economy
      $34
    Travel time is 3h 25m longer, but you will save $24

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $110
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $110
Futura 13h 15m 11:45 AM Mezcales Primera Plus 1:00 AM Mexico City Terminal del Sur  Economy $111
Futura 14h 35m 6:25 PM Mezcales Primera Plus 9:00 AM Mexico City Terminal del Sur  Economy $111
Futura 14h 35m 1:45 PM Mezcales Primera Plus 4:20 AM Mexico City Norte Bus Station  Economy $118
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $24? You can find the corresponding connections below.
    • Primera Plus
      13h 40m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $52
      • Waiting Time 0h 40m
    • SKPT de Viaje
      8h 30m
      0
      9:00 PM
      Guadalajara, JC
      Avenida de las Torres Bus Station
      5:30 AM
      Mexico City
      Norte Bus Station
      0
      SKPT de Viaje
      Premium Economy
      $34
    Travel time is 3h 25m longer, but you will save $24

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Primera Plus 10h 20m 8:30 PM Mezcales Primera Plus 6:50 AM Mexico City Norte Bus Station  Economy $110
Primera Plus 10h 15m 9:30 PM Mezcales Primera Plus 7:45 AM Mexico City Norte Bus Station  Economy $110
Futura 13h 15m 11:45 AM Mezcales Primera Plus 1:00 AM Mexico City Terminal del Sur  Economy $111
Futura 14h 35m 6:25 PM Mezcales Primera Plus 9:00 AM Mexico City Terminal del Sur  Economy $111
ETN Autobuses 11h 25m 7:50 PM Mezcales Vallarte Plus 7:15 AM Mexico City Norte Bus Station  Economy $156
  • Did you know that if you travel from Mezcales to Mexico City via Guadalajara, JC, you can save more than $24? You can find the corresponding connections below.
    • Primera Plus
      13h 40m
      0
      3:50 PM
      Mezcales
      Vallarte Plus
      8:20 PM
      Guadalajara, JC
      Central de Autobuses
      0
      Primera Plus
      Economy
      $52
      • Waiting Time 0h 40m
    • SKPT de Viaje
      8h 30m
      0
      9:00 PM
      Guadalajara, JC
      Avenida de las Torres Bus Station
      5:30 AM
      Mexico City
      Norte Bus Station
      0
      SKPT de Viaje
      Premium Economy
      $34
    Travel time is 3h 25m longer, but you will save $24

Best Price Offer: The price for the cheapest bus from Mezcales to Mexico City is $110 on 5/4/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Mezcales and Mexico City

See here how frequent the connections between Mezcales and Mexico City are, during different times and days of the week.
Friday is the busiest day, with more than 11 daily buses from Mezcales to Mexico City. Sunday has instead the fewest connections, with only 8 daily coaches between Mezcales and Mexico City.
The busiest time of the day is the Evening, with 48 buses from Mezcales to Mexico City, while Morning sees the fewest connections between Mezcales and Mexico City, with 7 offers.

Facts about the bus from Mezcales to Mexico City

Compare all providers like Futura, Primera Plus and ETN Autobuses that travel 9 times every day by bus from Mezcales to Mexico City in one click! Book your bus ticket from Mezcales to Mexico City starting from $110!

Cheapest Bus $110
Fastest Bus 10h 15m
Earliest Bus 11:45 AM
Latest Bus 9:30 PM
Daily Bus Routes 9 Ø
Distance 409.1 miles
Bus Companies Futura, Primera Plus, ETN Autobuses, Transportes Chihuahuenses and Elite

Cheapest bus connections from Mezcales to Mexico City

Every day, 9 buses from 5 bus companies leave Mezcales for Mexico City: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/05/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/03
Monday 05/04
Tuesday 05/05
$110
Wednesday 05/06
$156
Thursday 05/07
$111
Friday 05/08
$118
Saturday 05/09
$111
Sunday 05/10
$111
Monday 05/11
$110
Tuesday 05/12
$111
Wednesday 05/13
$111
Thursday 05/14
$111
Friday 05/15
$110
Saturday 05/16
$110
Sunday 05/17
$111
Monday 05/18
$111
Tuesday 05/19
$110
Wednesday 05/20
$111
Thursday 05/21
$110
Friday 05/22
$111
Saturday 05/23
$111
Sunday 05/24
$110
Monday 05/25
$111
Tuesday 05/26
$111
Wednesday 05/27
$110
Thursday 05/28
$111
Friday 05/29
$111
Saturday 05/30

The cheapest time to travel from Mezcales to Mexico City

See here on which day and which time of the day you can find the cheapest bus ticket from Mezcales to Mexico City, for the next 30 days.
With a price starting from $110, Sunday is the cheapest day for a bus from Mezcales to Mexico City. Sunday instead is the most expensive day with prices starting from $110.
Morning is the cheapest day time for bus tickets from Mezcales to Mexico City, with $110. Afternoon is the most expensive time of the day with prices starting from $118.

How to save money travelling from Mezcales to Mexico City

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mezcales to Mexico City in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mezcales to Mexico City, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mezcales to Mexico City are also emptier.

Beloved bus companies from Mezcales to Mexico City

These are the most booked bus companies between Mezcales to Mexico City from our users.

Futura from Mezcales to Mexico City

Futura

Here you will find the key facts about the Futura bus route Mezcales to Mexico City:

Cheapest Price $111
Fastest Bus 11h 13m
Earliest Bus 11:45 AM
Last Bus 9:15 PM
Daily Connections 6 Ø
Found on 5/5/2026

Primera Plus from Mezcales to Mexico City

Primera Plus

Here you will find the key facts about the Primera Plus bus route Mezcales to Mexico City:

Cheapest Price $110
Fastest Bus 10h 15m
Earliest Bus 8:30 PM
Last Bus 9:30 PM
Daily Connections 2 Ø
Found on 5/5/2026

All bus stations and stops in Mezcales and Mexico City

In the map below, you can see where to find all bus stations in Mezcales and Mexico City.

Service and Comfort on the bus from Mezcales to Mexico City

Want to know which seat classes are available on the buses from Mezcales to Mexico City? Or which bus companies serve the route Mezcales to Mexico City? Below you will find answers to your questions.

FAQs about the Mezcales to Mexico City bus

How much does a Mezcales Mexico City bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $110 and takes 10h 20m to reach Mexico City. Compare offers to save money!

How much could I save by comparing buses from Mezcales to Mexico City?

This route is offered by 5 companies with a range of ticket prices between $110 and $195. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mexico City.

On average, how many connections are available from Mezcales to Mexico City each day?

Every day, the Mezcales to Mexico City bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mezcales to Mexico City take?

The fastest bus from Mezcales to Mexico City is offered by Primera Plus and takes 10h 15m. Bus tickets for this connection cost $110. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mezcales to Mexico City?

The earliest bus arriving in Mexico City from Mezcales starts at 11:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mezcales to Mexico City?

The latest bus trip departing from Mezcales for Mexico City starts at 9:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mezcales Mexico City route?

When traveling by bus from Mezcales to Mexico City, passengers can travel with Futura, Primera Plus and ETN Autobuses. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mezcales and Mexico City?

You can check all the direct connections between Mezcales and Mexico City by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Futura, Primera Plus and ETN Autobuses.

What can I take with me on the Mezcales to Mexico City bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mezcales Mexico City bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mezcales Mexico City bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mezcales to Mexico City on your planned travel date.

How does CheckMyBus find the best bus deals from Mezcales to Mexico City?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Mezcales and Mexico City. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mezcales to Mexico City?

Prices and availability for 9 trips between Mezcales and Mexico City change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mezcales to Mexico City

Basic
Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mezcales and to Mexico City

Here’s an overview of the most popular bus routes to Mezcales and to Mexico City. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Mezcales from Bucerías Bus to Mezcales from Bucerías
Bus from Celaya to Mezcales Bus from Celaya to Mezcales
Bus Irapuato to Mezcales Bus Irapuato to Mezcales
Bus from Zacatecas, ZS to Mezcales Bus from Zacatecas, ZS to Mezcales
Buses Tlalnepantla de Baz, ME - Mexico City Buses Tlalnepantla de Baz, ME - Mexico City
Buses Sonoyta - Mexico City Buses Sonoyta - Mexico City
Bus from Cuautitlán Izcalli to Mexico City Bus from Cuautitlán Izcalli to Mexico City
Buses Mexicali to Mexico City Buses Mexicali to Mexico City
Popular Airport Shuttles to Mezcales and to Mexico City
CheckMyBus › Buses in Mexico › Bus to Mezcales › Bus to Mexico City

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.