Bus Mezcales to San Luis Potosí - Compare all Companies

Compare all timetables for the bus from Mezcales to San Luis Potosí

Here is a selection of the cheapest bus trips from the schedule from Mezcales to San Luis Potosí from various bus operators like ETN Autobuses for the next days.

today

tomorrow

Wednesday

Thursday

$148

Friday

Saturday

$148

Sunday

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ETN Autobuses	11h 50m	1:50 PM	Mezcales	Vallarte Plus	1:40 AM	San Luis Potosí	Central Bus Station		Premium Economy	$148	A Bus from ETN Autobuses goes from Vallarte Plus, Mezcales (Mexico) at 8/6/2026 1:50:00 PM to Central Bus Station, San Luis Potosí (Mexico) arriving at 8/7/2026 1:40:00 AM. 50 Premium Economy ticket for $148 per person are available. Travel duration is 11h 50m

Did you know that if you travel from Mezcales to San Luis Potosí via San Juan de los Lagos, you can save more than $49? You can find the corresponding connections below.
- Futura
  
  12h 28m
  
  0
  
  11:32 PM
  
  Mezcales
  Primera Plus
  
  6:12 AM
  
  San Juan de los Lagos
  Central Bus Station
  
  0
  
  Economy
  
  $67
  
  A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 8/5/2026 11:32:00 PM to Central Bus Station, San Juan de los Lagos (Mexico) arriving at 8/6/2026 6:12:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 6h 40m
- Primera Plus
  
  3h 0m
  
  0
  
  9:00 AM
  
  San Juan de los Lagos
  Central Bus Station
  
  12:00 PM
  
  San Luis Potosí
  Central Bus Station
  
  0
  
  Economy
  
  $32
  
  A Bus from Primera Plus goes from Central Bus Station, San Juan de los Lagos (Mexico) at 8/6/2026 9:00:00 AM to Central Bus Station, San Luis Potosí (Mexico) arriving at 8/6/2026 12:00:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 3h 0m
Travel time is 0h 38m longer, but you will save $49

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ETN Autobuses	11h 50m	1:50 PM	Mezcales	Vallarte Plus	1:40 AM	San Luis Potosí	Central Bus Station		Premium Economy	$148	A Bus from ETN Autobuses goes from Vallarte Plus, Mezcales (Mexico) at 8/8/2026 1:50:00 PM to Central Bus Station, San Luis Potosí (Mexico) arriving at 8/9/2026 1:40:00 AM. 50 Premium Economy ticket for $148 per person are available. Travel duration is 11h 50m

Did you know that if you travel from Mezcales to San Luis Potosí via San Juan de los Lagos, you can save more than $49? You can find the corresponding connections below.
- Futura
  
  12h 28m
  
  0
  
  11:32 PM
  
  Mezcales
  Primera Plus
  
  6:12 AM
  
  San Juan de los Lagos
  Central Bus Station
  
  0
  
  Economy
  
  $67
  
  A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 8/5/2026 11:32:00 PM to Central Bus Station, San Juan de los Lagos (Mexico) arriving at 8/6/2026 6:12:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 6h 40m
- Primera Plus
  
  3h 0m
  
  0
  
  9:00 AM
  
  San Juan de los Lagos
  Central Bus Station
  
  12:00 PM
  
  San Luis Potosí
  Central Bus Station
  
  0
  
  Economy
  
  $32
  
  A Bus from Primera Plus goes from Central Bus Station, San Juan de los Lagos (Mexico) at 8/6/2026 9:00:00 AM to Central Bus Station, San Luis Potosí (Mexico) arriving at 8/6/2026 12:00:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 3h 0m
Travel time is 0h 38m longer, but you will save $49

Best Price Offer: The price for the cheapest bus from Mezcales to San Luis Potosí is $147 on 8/21/2026. Flexible travelers save on ticket prices.

Facts about the bus from Mezcales to San Luis Potosí

Compare all providers like ETN Autobuses that travel 1 times every day by bus from Mezcales to San Luis Potosí in one click! Book your bus ticket from Mezcales to San Luis Potosí starting from $147!

Cheapest Bus	$147
Fastest Bus	11h 50m
Earliest Bus	1:50 PM
Latest Bus	1:50 PM
Daily Bus Routes	1 Ø
Distance	295.3 miles
Bus Companies	ETN Autobuses

Cheapest bus connections from Mezcales to San Luis Potosí

Every day, 1 buses from 1 bus companies leave Mezcales for San Luis Potosí: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/03/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/02

Monday 08/03

Tuesday 08/04

Wednesday 08/05

Thursday 08/06

$148

Friday 08/07

Saturday 08/08

$148

Sunday 08/09

Monday 08/10

$147

Tuesday 08/11

$147

Wednesday 08/12

Thursday 08/13

Friday 08/14

Saturday 08/15

$147

Sunday 08/16

$149

Monday 08/17

$149

Tuesday 08/18

$149

Wednesday 08/19

$148

Thursday 08/20

$148

Friday 08/21

$147

Saturday 08/22

Sunday 08/23

Monday 08/24

$148

Tuesday 08/25

Wednesday 08/26

$159

Thursday 08/27

$160

Friday 08/28

$161

Saturday 08/29

How to save money travelling from Mezcales to San Luis Potosí

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mezcales to San Luis Potosí in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mezcales to San Luis Potosí, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mezcales to San Luis Potosí are also emptier.

All bus stations and stops in Mezcales and San Luis Potosí

In the map below, you can see where to find all bus stations in Mezcales and San Luis Potosí.

Primera Plus

Blvrd Riviera Nayarit 171

Central Bus Station

Av Benito Juarez 250

Soriana El Paseo Bus Station

Doctor Salvador Nava Martínez 405

Av Constitución / Manual José Othón Bus Stop

Avenida Constitución 300

Barrio de Santiago

Bus Stop

Service and Comfort on the bus from Mezcales to San Luis Potosí

Want to know which seat classes are available on the buses from Mezcales to San Luis Potosí? Or which bus companies serve the route Mezcales to San Luis Potosí? Below you will find answers to your questions.

FAQs about the Mezcales to San Luis Potosí bus

How much does a Mezcales San Luis Potosí bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $147 and takes 11h 50m to reach San Luis Potosí. Compare offers to save money!

How much could I save by comparing buses from Mezcales to San Luis Potosí?

This route is offered by 1 companies with a range of ticket prices between $147 and $148. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Luis Potosí.

On average, how many connections are available from Mezcales to San Luis Potosí each day?

Every day, the Mezcales to San Luis Potosí bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mezcales to San Luis Potosí take?

The fastest bus from Mezcales to San Luis Potosí is offered by ETN Autobuses and takes 11h 50m. Bus tickets for this connection cost $148. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mezcales to San Luis Potosí?

The earliest bus arriving in San Luis Potosí from Mezcales starts at 1:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mezcales to San Luis Potosí?

The latest bus trip departing from Mezcales for San Luis Potosí starts at 1:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mezcales San Luis Potosí route?

When traveling by bus from Mezcales to San Luis Potosí, passengers can travel with ETN Autobuses. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mezcales and San Luis Potosí?

You can check all the direct connections between Mezcales and San Luis Potosí by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ETN Autobuses.

What can I take with me on the Mezcales to San Luis Potosí bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mezcales San Luis Potosí bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mezcales San Luis Potosí bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mezcales to San Luis Potosí on your planned travel date.

How does CheckMyBus find the best bus deals from Mezcales to San Luis Potosí?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Mezcales and San Luis Potosí. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mezcales to San Luis Potosí?

Prices and availability for 1 trips between Mezcales and San Luis Potosí change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mezcales to San Luis Potosí

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Mezcales and to San Luis Potosí

Here’s an overview of the most popular bus routes to Mezcales and to San Luis Potosí. Simply click on the connection of your choice, and you will find all the details about your bus route!