Bus from Mexico City to San Luis Potosí from $18

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Mexico City to San Luis Potosí

Here is a selection of the cheapest bus trips from the schedule from Mexico City to San Luis Potosí from various bus operators like Primera Plus, Flix Mexico or ETN Autobuses for the next days.

today
from $18
tomorrow
from $21
Saturday
from $18
Sunday
from $22
Monday
from $18
Tuesday
from $18
Wednesday
from $18

Cheapest bus trips today

Prices are for one way and one person
  • Flix Mexico
    6h 40m
    0
    7:00 AM
    Mexico City
    San Pedro Santa Clara Bus Stop
    1:40 PM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    Flix Mexico
    Economy
    $18
  • FlixBus
    6h 40m
    0
    7:00 AM
    Mexico City
    San Pedro Santa Clara Bus Stop
    1:40 PM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    FlixBus
    Economy
    $20
  • Viajes Seguro
    5h 10m
    0
    10:50 AM
    Mexico City
    Norte Bus Station
    4:00 PM
    San Luis Potosí
    Central Bus Station
    0
    Viajes Seguro
    Economy
    $30
  • Futura
    6h 50m
    0
    1:00 AM
    Mexico City
    Terminal del Sur
    7:50 AM
    San Luis Potosí
    Central Bus Station
    0
    Futura
    First Class
    $45
  • Transportes Frontera
    5h 35m
    0
    4:00 PM
    Mexico City
    Norte Bus Station
    9:35 PM
    San Luis Potosí
    Central Bus Station
    0
    Transportes Frontera
    Economy
    $49

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Flix Mexico
    7h 20m
    0
    10:00 PM
    Mexico City
    San Pedro Santa Clara Bus Stop
    5:20 AM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    Flix Mexico
    Economy
    $21
  • Viajes Seguro
    5h 10m
    0
    10:50 AM
    Mexico City
    Norte Bus Station
    4:00 PM
    San Luis Potosí
    Central Bus Station
    0
    Viajes Seguro
    Economy
    $30
  • Senda TDN Diamante
    6h 25m
    0
    8:45 AM
    Mexico City
    Norte Bus Station
    3:10 PM
    San Luis Potosí
    Central Bus Station
    0
    Senda TDN Diamante
    Economy
    $44
  • Primera Plus
    5h 0m
    0
    7:00 AM
    Mexico City
    Norte Bus Station
    12:00 PM
    San Luis Potosí
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Turistar
    6h 45m
    0
    7:00 AM
    Mexico City
    Taxqueña Bus Station
    1:45 PM
    San Luis Potosí
    Central Bus Station
    0
    Turistar
    Economy
    $67
  • Did you know that if you travel from Mexico City to San Luis Potosí via Santiago de Queretaro, you can save more than $4? You can find the corresponding connections below.
    • Busbud
      6h 55m
      0
      7:25 PM
      Mexico City
      Mexico City Buenavista (Fórum Buenavista) Bus Stop
      10:55 PM
      Santiago de Queretaro
      Centro Comercial Galeria
      0
      Busbud
      Economy
      $7
      • Waiting Time 0h 10m
    • Busbud
      3h 15m
      0
      11:05 PM
      Santiago de Queretaro
      Centro Comercial Galeria
      2:20 AM
      San Luis Potosí
      Soriana, Plaza El Paseo Bus Stop
      0
      Busbud
      Economy
      $10
    Travel time is 1h 55m longer, but you will save $4

Cheapest bus trips Saturday

Prices are for one way and one person
  • Flix Mexico
    6h 55m
    0
    7:25 PM
    Mexico City
    Mexico City Buenavista (Fórum Buenavista) Bus Stop
    2:20 AM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    Flix Mexico
    Economy
    $18
  • Viajes Seguro
    5h 30m
    0
    10:50 AM
    Mexico City
    Parque Delta Bus Station
    4:20 PM
    San Luis Potosí
    Central Bus Station
    0
    Viajes Seguro
    Economy
    $24
  • Primera Plus
    5h 0m
    0
    7:00 AM
    Mexico City
    Norte Bus Station
    12:00 PM
    San Luis Potosí
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • ETN Autobuses
    6h 0m
    0
    10:30 AM
    Mexico City
    Norte Bus Station
    4:30 PM
    San Luis Potosí
    Central Bus Station
    0
    ETN Autobuses
    Economy
    $67
  • Turistar
    5h 45m
    0
    11:00 PM
    Mexico City
    Norte Bus Station
    4:45 AM
    San Luis Potosí
    Central Bus Station
    0
    Turistar
    Economy
    $67

Cheapest bus trips Sunday

Prices are for one way and one person
  • Flix Mexico
    7h 25m
    0
    7:00 AM
    Mexico City
    San Pedro Santa Clara Bus Stop
    2:25 PM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    Flix Mexico
    Economy
    $22
  • FlixBus
    7h 25m
    0
    7:00 AM
    Mexico City
    San Pedro Santa Clara Bus Stop
    2:25 PM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    FlixBus
    Economy
    $23
  • Viajes Seguro
    5h 40m
    0
    10:50 AM
    Mexico City
    Parque Delta Bus Station
    4:30 PM
    San Luis Potosí
    Central Bus Station
    0
    Viajes Seguro
    Economy
    $24
  • Senda TDN Diamante
    6h 25m
    0
    8:45 AM
    Mexico City
    Norte Bus Station
    3:10 PM
    San Luis Potosí
    Central Bus Station
    0
    Senda TDN Diamante
    Economy
    $43
  • Primera Plus
    5h 0m
    0
    7:00 AM
    Mexico City
    Norte Bus Station
    12:00 PM
    San Luis Potosí
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Did you know that if you travel from Mexico City to San Luis Potosí via Santiago de Queretaro, you can save more than $5? You can find the corresponding connections below.
    • Busbud
      6h 55m
      0
      7:25 PM
      Mexico City
      Mexico City Buenavista (Fórum Buenavista) Bus Stop
      10:55 PM
      Santiago de Queretaro
      Centro Comercial Galeria
      0
      Busbud
      Economy
      $7
      • Waiting Time 0h 10m
    • Busbud
      3h 15m
      0
      11:05 PM
      Santiago de Queretaro
      Centro Comercial Galeria
      2:20 AM
      San Luis Potosí
      Soriana, Plaza El Paseo Bus Stop
      0
      Busbud
      Economy
      $10
    Travel time is 1h 55m longer, but you will save $5

Cheapest bus trips Monday

Prices are for one way and one person
  • Flix Mexico
    7h 25m
    0
    7:00 AM
    Mexico City
    San Pedro Santa Clara Bus Stop
    2:25 PM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    Flix Mexico
    Economy
    $18
  • FlixBus
    7h 25m
    0
    7:00 AM
    Mexico City
    San Pedro Santa Clara Bus Stop
    2:25 PM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    FlixBus
    Economy
    $20
  • Viajes Seguro
    5h 30m
    0
    10:50 AM
    Mexico City
    Parque Delta Bus Station
    4:20 PM
    San Luis Potosí
    Central Bus Station
    0
    Viajes Seguro
    Economy
    $24
  • Primera Plus
    5h 0m
    0
    7:00 AM
    Mexico City
    Norte Bus Station
    12:00 PM
    San Luis Potosí
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • Turistar
    6h 45m
    0
    7:00 AM
    Mexico City
    Taxqueña Bus Station
    1:45 PM
    San Luis Potosí
    Central Bus Station
    0
    Turistar
    Economy
    $67

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Flix Mexico
    7h 25m
    0
    7:00 AM
    Mexico City
    San Pedro Santa Clara Bus Stop
    2:25 PM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    Flix Mexico
    Economy
    $18
  • FlixBus
    7h 25m
    0
    7:00 AM
    Mexico City
    San Pedro Santa Clara Bus Stop
    2:25 PM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    FlixBus
    Economy
    $20
  • Viajes Seguro
    5h 30m
    0
    10:50 AM
    Mexico City
    Parque Delta Bus Station
    4:20 PM
    San Luis Potosí
    Central Bus Station
    0
    Viajes Seguro
    Economy
    $24
  • Primera Plus
    5h 0m
    0
    7:00 AM
    Mexico City
    Norte Bus Station
    12:00 PM
    San Luis Potosí
    Central Bus Station
    0
    Primera Plus
    Economy
    $36
  • Turistar
    6h 45m
    0
    7:00 AM
    Mexico City
    Taxqueña Bus Station
    1:45 PM
    San Luis Potosí
    Central Bus Station
    0
    Turistar
    Economy
    $67

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Flix Mexico
    7h 25m
    0
    7:00 AM
    Mexico City
    San Pedro Santa Clara Bus Stop
    2:25 PM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    Flix Mexico
    Economy
    $18
  • FlixBus
    7h 25m
    0
    7:00 AM
    Mexico City
    San Pedro Santa Clara Bus Stop
    2:25 PM
    San Luis Potosí
    Soriana, Plaza El Paseo Bus Stop
    0
    FlixBus
    Economy
    $20
  • Viajes Seguro
    5h 30m
    0
    10:50 AM
    Mexico City
    Parque Delta Bus Station
    4:20 PM
    San Luis Potosí
    Central Bus Station
    0
    Viajes Seguro
    Economy
    $24
  • Primera Plus
    5h 0m
    0
    7:00 AM
    Mexico City
    Norte Bus Station
    12:00 PM
    San Luis Potosí
    Central Bus Station
    0
    Primera Plus
    Economy
    $49
  • ETN Autobuses
    6h 0m
    0
    10:30 AM
    Mexico City
    Norte Bus Station
    4:30 PM
    San Luis Potosí
    Central Bus Station
    0
    ETN Autobuses
    Economy
    $67

Frequency of bus connections between Mexico City and San Luis Potosí

See here how frequent the connections between Mexico City and San Luis Potosí are, during different times and days of the week.
Thursday is the busiest day, with more than 89 daily buses from Mexico City to San Luis Potosí. Tuesday has instead the fewest connections, with only 43 daily coaches between Mexico City and San Luis Potosí.
The busiest time of the day is the Evening, with 140 buses from Mexico City to San Luis Potosí, while Night sees the fewest connections between Mexico City and San Luis Potosí, with 4 offers.

Facts about the bus from Mexico City to San Luis Potosí

Compare all providers like Primera Plus, Flix Mexico and ETN Autobuses that travel 56 times every day by bus from Mexico City to San Luis Potosí in one click! Book your bus ticket from Mexico City to San Luis Potosí starting from $18!

Cheapest Bus $18
Fastest Bus 4h 45m
Earliest Bus 12:30 AM
Latest Bus 11:59 PM
Daily Bus Routes 56 Ø
Distance 221.3 miles
Bus Companies Primera Plus, Flix Mexico, ETN Autobuses, Turistar, FlixBus, Futura, Viajes Seguro, Senda TDN Diamante, Transportes Chihuahuenses, Transportes Frontera and 1 more.

Cheapest bus connections from Mexico City to San Luis Potosí

Every day, 56 buses from 11 bus companies leave Mexico City for San Luis Potosí: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/03/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/29
Monday 06/30
Tuesday 07/01
Wednesday 07/02
Thursday 07/03
$38
Friday 07/04
$21
Saturday 07/05
$67
Sunday 07/06
$38
Monday 07/07
$67
Tuesday 07/08
$36
Wednesday 07/09
$38
Thursday 07/10
$38
Friday 07/11
$51
Saturday 07/12
$18
Sunday 07/13
$20
Monday 07/14
$38
Tuesday 07/15
$38
Wednesday 07/16
$20
Thursday 07/17
$20
Friday 07/18
$38
Saturday 07/19
$18
Sunday 07/20
$38
Monday 07/21
$18
Tuesday 07/22
$38
Wednesday 07/23
$18
Thursday 07/24
$18
Friday 07/25
$38
Saturday 07/26

The cheapest time to travel from Mexico City to San Luis Potosí

See here on which day and which time of the day you can find the cheapest bus ticket from Mexico City to San Luis Potosí, for the next 30 days.
With a price starting from $18, Monday is the cheapest day for a bus from Mexico City to San Luis Potosí. Sunday instead is the most expensive day with prices starting from $22.
Morning is the cheapest day time for bus tickets from Mexico City to San Luis Potosí, with $18. Night is the most expensive time of the day with prices starting from $45.

How to save money travelling from Mexico City to San Luis Potosí

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mexico City to San Luis Potosí in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mexico City to San Luis Potosí, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mexico City to San Luis Potosí are also emptier.

Beloved bus companies from Mexico City to San Luis Potosí

These are the most booked bus companies between Mexico City to San Luis Potosí from our users.

Futura from Mexico City to San Luis Potosí

Futura

Here you will find the key facts about the Futura bus route Mexico City to San Luis Potosí:

Cheapest Price $45
Fastest Bus 4h 45m
Earliest Bus 12:30 AM
Last Bus 11:59 PM
Daily Connections 29 Ø
Found on 7/2/2025

Primera Plus from Mexico City to San Luis Potosí

Primera Plus

Here you will find the key facts about the Primera Plus bus route Mexico City to San Luis Potosí:

Cheapest Price $36
Fastest Bus 4h 59m
Earliest Bus 7:00 AM
Last Bus 11:59 PM
Daily Connections 13 Ø
Found on 7/2/2025

Viajes Seguro from Mexico City to San Luis Potosí

Viajes Seguro

Here you will find the key facts about the Viajes Seguro bus route Mexico City to San Luis Potosí:

Cheapest Price $24
Fastest Bus 5h 10m
Earliest Bus 10:50 AM
Last Bus 10:50 AM
Daily Connections 2 Ø
Found on 7/2/2025

All bus stations and stops in Mexico City and San Luis Potosí

In the map below, you can see where to find all bus stations in Mexico City and San Luis Potosí.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mexico City to San Luis Potosí? Compare all modes of transports from Mexico City to San Luis Potosí.

Service and Comfort on the bus from Mexico City to San Luis Potosí

Want to know which seat classes are available on the buses from Mexico City to San Luis Potosí? Or which bus companies serve the route Mexico City to San Luis Potosí? Below you will find answers to your questions.

FAQs about the Mexico City to San Luis Potosí bus

How much does a Mexico City San Luis Potosí bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $18 and takes 6h 40m to reach San Luis Potosí. Compare offers to save money!

How much could I save by comparing buses from Mexico City to San Luis Potosí?

This route is offered by 11 companies with a range of ticket prices between $18 and $69. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Luis Potosí.

On average, how many connections are available from Mexico City to San Luis Potosí each day?

Every day, the Mexico City to San Luis Potosí bus route is served by approximately 56 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mexico City to San Luis Potosí take?

The fastest bus from Mexico City to San Luis Potosí is offered by Futura and takes 4h 45m. Bus tickets for this connection cost $60. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mexico City to San Luis Potosí?

The earliest bus arriving in San Luis Potosí from Mexico City starts at 12:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mexico City to San Luis Potosí?

The latest bus trip departing from Mexico City for San Luis Potosí starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mexico City San Luis Potosí route?

When traveling by bus from Mexico City to San Luis Potosí, passengers can travel with Primera Plus, Flix Mexico and ETN Autobuses. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mexico City and San Luis Potosí?

You can check all the direct connections between Mexico City and San Luis Potosí by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Primera Plus, Flix Mexico and ETN Autobuses.

What can I take with me on the Mexico City to San Luis Potosí bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mexico City San Luis Potosí bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mexico City San Luis Potosí bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mexico City to San Luis Potosí on your planned travel date.

Available seat classes which are offered on the bus route Mexico City to San Luis Potosí

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Mexico City and to San Luis Potosí

Here’s an overview of the most popular bus routes to Mexico City and to San Luis Potosí. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Tijuana, BC - Mexico City Bus Tijuana, BC - Mexico City
Buses Guadalajara, JC - Mexico City Buses Guadalajara, JC - Mexico City
Buses Tepoztlán - Mexico City Buses Tepoztlán - Mexico City
Buses Cuernavaca to Mexico City Buses Cuernavaca to Mexico City
Bus to San Luis Potosí from Dallas Bus to San Luis Potosí from Dallas
Bus to San Luis Potosí from San Miguel de Allende Bus to San Luis Potosí from San Miguel de Allende
Bus from Guadalajara, JC to San Luis Potosí Bus from Guadalajara, JC to San Luis Potosí
Buses Puerto Vallarta - San Luis Potosí Buses Puerto Vallarta - San Luis Potosí
Popular Airport Shuttles to Mexico City and to San Luis Potosí
CheckMyBus › Buses in Mexico › Bus to Mexico City › Bus to San Luis Potosí

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus offers, we and our partners use technical, analytical, and marketing cookies to personalize the ads. We remember your anonymized details to provide a personalized experience.