Bus San Diego to San Luis Potosí - Compare all Companies

Compare all timetables for the bus from San Diego to San Luis Potosí

Here is a selection of the cheapest bus trips from the schedule from San Diego to San Luis Potosí from various bus operators like FlixBus or Greyhound US for the next days.

today

$218

tomorrow

Tuesday

$222

Wednesday

$219

Thursday

$221

Friday

$217

Saturday

$217

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	56h 40m	1:10 PM	San Diego	Seaport Village	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$218	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 6/14/2026 1:10:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/16/2026 10:50:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 56h 40m
FlixBus	60h 25m	9:25 AM	San Diego	Old Town Transit Center	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$219	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/14/2026 9:25:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/16/2026 10:50:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 60h 25m
Greyhound US	52h 0m	9:50 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$219	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/14/2026 9:50:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/16/2026 2:50:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 52h 0m
FlixBus	54h 15m	7:35 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$220	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/14/2026 7:35:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/16/2026 2:50:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 54h 15m
Greyhound US	65h 55m	7:55 PM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$244	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/14/2026 7:55:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/17/2026 2:50:00 PM. 50 Economy ticket for $244 per person are available. Travel duration is 65h 55m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	53h 55m	7:55 AM	San Diego	La Jolla Village	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$222	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 6/16/2026 7:55:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/18/2026 2:50:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 53h 55m
FlixBus	54h 15m	7:35 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$223	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/16/2026 7:35:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/18/2026 2:50:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 54h 15m
Greyhound US	57h 50m	7:55 PM	San Diego	Old Town Transit Center	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$238	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/16/2026 7:55:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/19/2026 6:45:00 AM. 50 Economy ticket for $238 per person are available. Travel duration is 57h 50m
FlixBus	53h 20m	1:35 PM	San Diego	La Jolla Village	7:55 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$250	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 6/16/2026 1:35:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/18/2026 7:55:00 PM. 50 Economy ticket for $250 per person are available. Travel duration is 53h 20m
Greyhound US	59h 50m	7:05 AM	San Diego	Old Town Transit Center	7:55 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$251	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/16/2026 7:05:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/18/2026 7:55:00 PM. 50 Economy ticket for $251 per person are available. Travel duration is 59h 50m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	54h 15m	7:35 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$219	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/17/2026 7:35:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/19/2026 2:50:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 54h 15m
Greyhound US	57h 50m	7:55 PM	San Diego	Old Town Transit Center	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$221	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/17/2026 7:55:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/20/2026 6:45:00 AM. 50 Economy ticket for $221 per person are available. Travel duration is 57h 50m
FlixBus	53h 55m	7:55 AM	San Diego	La Jolla Village	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$222	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 6/17/2026 7:55:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/19/2026 2:50:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 53h 55m
FlixBus	53h 45m	1:10 PM	San Diego	Seaport Village	7:55 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$267	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 6/17/2026 1:10:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/19/2026 7:55:00 PM. 50 Economy ticket for $267 per person are available. Travel duration is 53h 45m
Greyhound US	59h 50m	7:05 AM	San Diego	Old Town Transit Center	7:55 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$269	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/17/2026 7:05:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/19/2026 7:55:00 PM. 50 Economy ticket for $269 per person are available. Travel duration is 59h 50m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	57h 50m	7:55 PM	San Diego	Old Town Transit Center	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$221	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/18/2026 7:55:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/21/2026 6:45:00 AM. 50 Economy ticket for $221 per person are available. Travel duration is 57h 50m
Greyhound US	52h 0m	9:50 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$225	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/18/2026 9:50:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/20/2026 2:50:00 PM. 50 Economy ticket for $225 per person are available. Travel duration is 52h 0m
FlixBus	54h 15m	7:35 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$226	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/18/2026 7:35:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/20/2026 2:50:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 54h 15m
FlixBus	53h 45m	1:10 PM	San Diego	Seaport Village	7:55 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$266	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 6/18/2026 1:10:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/20/2026 7:55:00 PM. 50 Economy ticket for $266 per person are available. Travel duration is 53h 45m
FlixBus	57h 30m	9:25 AM	San Diego	Old Town Transit Center	7:55 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$268	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/18/2026 9:25:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/20/2026 7:55:00 PM. 50 Economy ticket for $268 per person are available. Travel duration is 57h 30m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	57h 50m	7:55 PM	San Diego	Old Town Transit Center	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$217	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/19/2026 7:55:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/22/2026 6:45:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 57h 50m
FlixBus	53h 45m	1:10 PM	San Diego	Seaport Village	7:55 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$218	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 6/19/2026 1:10:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/21/2026 7:55:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 53h 45m
FlixBus	57h 30m	9:25 AM	San Diego	Old Town Transit Center	7:55 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$219	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/19/2026 9:25:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/21/2026 7:55:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 57h 30m
FlixBus	53h 20m	1:35 PM	San Diego	La Jolla Village	7:55 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$222	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 6/19/2026 1:35:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/21/2026 7:55:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 53h 20m
Greyhound US	52h 0m	9:50 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$269	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/19/2026 9:50:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/21/2026 2:50:00 PM. 50 Economy ticket for $269 per person are available. Travel duration is 52h 0m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	57h 30m	9:25 AM	San Diego	Old Town Transit Center	7:55 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$217	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/20/2026 9:25:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/22/2026 7:55:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 57h 30m
Greyhound US	57h 50m	7:55 PM	San Diego	Old Town Transit Center	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$217	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/20/2026 7:55:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/23/2026 6:45:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 57h 50m
FlixBus	53h 45m	1:10 PM	San Diego	Seaport Village	7:55 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$218	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 6/20/2026 1:10:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/22/2026 7:55:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 53h 45m
Greyhound US	52h 0m	9:50 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$218	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 6/20/2026 9:50:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/22/2026 2:50:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 52h 0m
FlixBus	54h 15m	7:35 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$219	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 6/20/2026 7:35:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 6/22/2026 2:50:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 54h 15m

Best Price Offer: The price for the cheapest bus from San Diego to San Luis Potosí is $217 on 6/20/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Diego and San Luis Potosí

See here how frequent the connections between San Diego and San Luis Potosí are, during different times and days of the week.

Sunday is the busiest day, with more than 12 daily buses from San Diego to San Luis Potosí. Thursday has instead the fewest connections, with only 5 daily coaches between San Diego and San Luis Potosí.

The busiest time of the day is the Morning, with 35 buses from San Diego to San Luis Potosí, while Evening sees the fewest connections between San Diego and San Luis Potosí, with 10 offers.

Facts about the bus from San Diego to San Luis Potosí

Compare all providers like FlixBus and Greyhound US that travel 10 times every day by bus from San Diego to San Luis Potosí in one click! Book your bus ticket from San Diego to San Luis Potosí starting from $217!

Cheapest Bus	$217
Fastest Bus	53h 0m
Earliest Bus	7:35 AM
Latest Bus	7:55 PM
Daily Bus Routes	10 Ø
Distance	1,231.0 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from San Diego to San Luis Potosí

Every day, 10 buses from 2 bus companies leave San Diego for San Luis Potosí: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/14/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/14

$218

Monday 06/15

Tuesday 06/16

$222

Wednesday 06/17

$222

Thursday 06/18

$221

Friday 06/19

$217

Saturday 06/20

$217

Sunday 06/21

$221

Monday 06/22

$217

Tuesday 06/23

$217

Wednesday 06/24

$217

Thursday 06/25

$221

Friday 06/26

$217

Saturday 06/27

$217

Sunday 06/28

$221

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

$224

Friday 07/10

Saturday 07/11

The cheapest time to travel from San Diego to San Luis Potosí

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to San Luis Potosí, for the next 30 days.

With a price starting from $217, Tuesday is the cheapest day for a bus from San Diego to San Luis Potosí. Thursday instead is the most expensive day with prices starting from $221.

Morning is the cheapest day time for bus tickets from San Diego to San Luis Potosí, with $217. Afternoon is the most expensive time of the day with prices starting from $218.

How to save money travelling from San Diego to San Luis Potosí

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to San Luis Potosí in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to San Luis Potosí, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to San Luis Potosí are also emptier.

All bus stations and stops in San Diego and San Luis Potosí

In the map below, you can see where to find all bus stations in San Diego and San Luis Potosí.

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

La Jolla Village

Hyatt Regency

Downtown

La Valle & 2705 Bus Stop

Central Bus Station

Av Benito Juarez 250

Soriana El Paseo Bus Station

Doctor Salvador Nava Martínez 405

Av Constitución / Manual José Othón Bus Stop

Avenida Constitución 300

Barrio de Santiago

Bus Stop

Service and Comfort on the bus from San Diego to San Luis Potosí

Want to know which seat classes are available on the buses from San Diego to San Luis Potosí? Or which bus companies serve the route San Diego to San Luis Potosí? Below you will find answers to your questions.

FAQs about the San Diego to San Luis Potosí bus

How much does a San Diego San Luis Potosí bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $217 and takes 58h 30m to reach San Luis Potosí. Compare offers to save money!

How much could I save by comparing buses from San Diego to San Luis Potosí?

This route is offered by 2 companies with a range of ticket prices between $217 and $276. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Luis Potosí.

On average, how many connections are available from San Diego to San Luis Potosí each day?

Every day, the San Diego to San Luis Potosí bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to San Luis Potosí take?

The fastest bus from San Diego to San Luis Potosí is offered by Greyhound US and takes 53h 0m. Bus tickets for this connection cost $223. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to San Luis Potosí?

The earliest bus arriving in San Luis Potosí from San Diego starts at 7:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to San Luis Potosí?

The latest bus trip departing from San Diego for San Luis Potosí starts at 7:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego San Luis Potosí route?

When traveling by bus from San Diego to San Luis Potosí, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and San Luis Potosí?

You can check all the direct connections between San Diego and San Luis Potosí by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to San Luis Potosí bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego San Luis Potosí bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego San Luis Potosí bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to San Luis Potosí on your planned travel date.

How does CheckMyBus find the best bus deals from San Diego to San Luis Potosí?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between San Diego and San Luis Potosí. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Diego to San Luis Potosí?

Prices and availability for 10 trips between San Diego and San Luis Potosí change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Diego to San Luis Potosí

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to San Luis Potosí

Here’s an overview of the most popular bus routes to San Diego and to San Luis Potosí. Simply click on the connection of your choice, and you will find all the details about your bus route!