Bus San Diego to San Luis Potosí - Compare all Companies

Compare all timetables for the bus from San Diego to San Luis Potosí

Here is a selection of the cheapest bus trips from the schedule from San Diego to San Luis Potosí from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$218

Friday

Saturday

$252

Sunday

$296

Monday

$218

Tuesday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	56h 40m	1:10 PM	San Diego	Seaport Village	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$218	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 4/30/2026 1:10:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/2/2026 10:50:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 56h 40m
FlixBus	60h 25m	9:25 AM	San Diego	Old Town Transit Center	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$219	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 4/30/2026 9:25:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/2/2026 10:50:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 60h 25m
FlixBus	56h 15m	1:35 PM	San Diego	La Jolla Village	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$222	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 4/30/2026 1:35:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/2/2026 10:50:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 56h 15m
Greyhound US	52h 0m	9:50 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$228	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 4/30/2026 9:50:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/2/2026 2:50:00 PM. 50 Economy ticket for $228 per person are available. Travel duration is 52h 0m
Greyhound US	58h 10m	7:35 PM	San Diego	Old Town Transit Center	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$237	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 4/30/2026 7:35:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/3/2026 6:45:00 AM. 50 Economy ticket for $237 per person are available. Travel duration is 58h 10m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	58h 10m	7:35 PM	San Diego	Old Town Transit Center	6:45 AM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$252	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/2/2026 7:35:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/5/2026 6:45:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 58h 10m
FlixBus	54h 15m	7:35 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$271	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/2/2026 7:35:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/4/2026 2:50:00 PM. 50 Economy ticket for $271 per person are available. Travel duration is 54h 15m
Greyhound US	52h 0m	9:50 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$272	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/2/2026 9:50:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/4/2026 2:50:00 PM. 50 Economy ticket for $272 per person are available. Travel duration is 52h 0m
FlixBus	53h 55m	7:55 AM	San Diego	La Jolla Village	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$279	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 5/2/2026 7:55:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/4/2026 2:50:00 PM. 50 Economy ticket for $279 per person are available. Travel duration is 53h 55m
FlixBus	56h 40m	1:10 PM	San Diego	Seaport Village	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$324	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 5/2/2026 1:10:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/4/2026 10:50:00 PM. 50 Economy ticket for $324 per person are available. Travel duration is 56h 40m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	54h 15m	7:35 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$296	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/3/2026 7:35:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/5/2026 2:50:00 PM. 50 Economy ticket for $296 per person are available. Travel duration is 54h 15m
Greyhound US	66h 15m	7:35 PM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$297	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/3/2026 7:35:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/6/2026 2:50:00 PM. 50 Economy ticket for $297 per person are available. Travel duration is 66h 15m
Greyhound US	52h 0m	9:50 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$298	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/3/2026 9:50:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/5/2026 2:50:00 PM. 50 Economy ticket for $298 per person are available. Travel duration is 52h 0m
FlixBus	53h 55m	7:55 AM	San Diego	La Jolla Village	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$305	A Bus from FlixBus goes from La Jolla Village, San Diego (USA) at 5/3/2026 7:55:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/5/2026 2:50:00 PM. 50 Economy ticket for $305 per person are available. Travel duration is 53h 55m
FlixBus	56h 40m	1:10 PM	San Diego	Seaport Village	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$308	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 5/3/2026 1:10:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/5/2026 10:50:00 PM. 50 Economy ticket for $308 per person are available. Travel duration is 56h 40m

Did you know that if you travel from San Diego to San Luis Potosí via Aguascalientes, you can save more than $67? You can find the corresponding connections below.
- Greyhound US
  
  71h 20m
  
  0
  
  9:50 AM
  
  San Diego
  Old Town Transit Center
  
  9:20 PM
  
  Aguascalientes
  Ignacio Valtierra Bus Stop
  
  0
  
  Economy
  
  $217
  
  A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/1/2026 9:50:00 AM to Ignacio Valtierra Bus Stop, Aguascalientes (Mexico) arriving at 5/3/2026 9:20:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 58h 30m
- Flix Mexico
  
  2h 45m
  
  0
  
  7:25 AM
  
  Aguascalientes
  Ignacio Valtierra Bus Stop
  
  10:10 AM
  
  San Luis Potosí
  Soriana El Paseo Bus Station
  
  0
  
  Economy
  
  $12
  
  A Bus from Flix Mexico goes from Ignacio Valtierra Bus Stop, Aguascalientes (Mexico) at 5/4/2026 7:25:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/4/2026 10:10:00 AM. 50 Economy ticket for $12 per person are available. Travel duration is 2h 45m
Travel time is 18h 20m longer, but you will save $67

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	54h 15m	7:35 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$218	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/4/2026 7:35:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/6/2026 2:50:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 54h 15m
FlixBus	56h 40m	1:10 PM	San Diego	Seaport Village	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$218	A Bus from FlixBus goes from Seaport Village, San Diego (USA) at 5/4/2026 1:10:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/6/2026 10:50:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 56h 40m
FlixBus	60h 25m	9:25 AM	San Diego	Old Town Transit Center	10:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$219	A Bus from FlixBus goes from Old Town Transit Center, San Diego (USA) at 5/4/2026 9:25:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/6/2026 10:50:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 60h 25m
Greyhound US	52h 0m	9:50 AM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$221	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/4/2026 9:50:00 AM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/6/2026 2:50:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 52h 0m
Greyhound US	66h 15m	7:35 PM	San Diego	Old Town Transit Center	2:50 PM	San Luis Potosí	Soriana El Paseo Bus Station	Economy	$221	A Bus from Greyhound US goes from Old Town Transit Center, San Diego (USA) at 5/4/2026 7:35:00 PM to Soriana El Paseo Bus Station, San Luis Potosí (Mexico) arriving at 5/7/2026 2:50:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 66h 15m

Best Price Offer: The price for the cheapest bus from San Diego to San Luis Potosí is $214 on 4/27/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Diego and San Luis Potosí

See here how frequent the connections between San Diego and San Luis Potosí are, during different times and days of the week.

Sunday is the busiest day, with more than 12 daily buses from San Diego to San Luis Potosí. Sunday has instead the fewest connections, with only 12 daily coaches between San Diego and San Luis Potosí.

The busiest time of the day is the Morning, with 28 buses from San Diego to San Luis Potosí, while Evening sees the fewest connections between San Diego and San Luis Potosí, with 8 offers.

Facts about the bus from San Diego to San Luis Potosí

Compare all providers like FlixBus and Greyhound US that travel 12 times every day by bus from San Diego to San Luis Potosí in one click! Book your bus ticket from San Diego to San Luis Potosí starting from $214!

Cheapest Bus	$214
Fastest Bus	53h 0m
Earliest Bus	7:35 AM
Latest Bus	7:35 PM
Daily Bus Routes	12 Ø
Distance	1,231.0 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from San Diego to San Luis Potosí

Every day, 12 buses from 2 bus companies leave San Diego for San Luis Potosí: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/29/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/26

Monday 04/27

Tuesday 04/28

Wednesday 04/29

Thursday 04/30

$218

Friday 05/01

Saturday 05/02

$256

Sunday 05/03

$296

Monday 05/04

$218

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$218

Saturday 05/09

$217

Sunday 05/10

Monday 05/11

$223

Tuesday 05/12

$223

Wednesday 05/13

$223

Thursday 05/14

$223

Friday 05/15

$221

Saturday 05/16

$223

Sunday 05/17

$219

Monday 05/18

$221

Tuesday 05/19

$221

Wednesday 05/20

$222

Thursday 05/21

$223

Friday 05/22

$223

Saturday 05/23

The cheapest time to travel from San Diego to San Luis Potosí

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to San Luis Potosí, for the next 30 days.

With a price starting from $217, Saturday is the cheapest day for a bus from San Diego to San Luis Potosí. Sunday instead is the most expensive day with prices starting from $219.

Morning is the cheapest day time for bus tickets from San Diego to San Luis Potosí, with $218. Evening is the most expensive time of the day with prices starting from $221.

How to save money travelling from San Diego to San Luis Potosí

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to San Luis Potosí in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to San Luis Potosí, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to San Luis Potosí are also emptier.

Beloved bus companies from San Diego to San Luis Potosí

These are the most booked bus companies between San Diego to San Luis Potosí from our users.

Greyhound US from San Diego to San Luis Potosí

Here you will find the key facts about the Greyhound US bus route San Diego to San Luis Potosí:

Cheapest Price	$221
Fastest Bus	53h 0m
Earliest Bus	9:50 AM
Last Bus	7:35 PM
Daily Connections	4 Ø
Found on	4/4/2026

All bus stations and stops in San Diego and San Luis Potosí

In the map below, you can see where to find all bus stations in San Diego and San Luis Potosí.

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Central Bus Station

Av Benito Juarez 250

Soriana El Paseo Bus Station

Doctor Salvador Nava Martínez 405

Av Constitución / Manual José Othón Bus Stop

Avenida Constitución 300

Bus Stop

Anillo Periférico

Service and Comfort on the bus from San Diego to San Luis Potosí

Want to know which seat classes are available on the buses from San Diego to San Luis Potosí? Or which bus companies serve the route San Diego to San Luis Potosí? Below you will find answers to your questions.

FAQs about the San Diego to San Luis Potosí bus

How much does a San Diego San Luis Potosí bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $214 and takes 57h 40m to reach San Luis Potosí. Compare offers to save money!

How much could I save by comparing buses from San Diego to San Luis Potosí?

This route is offered by 2 companies with a range of ticket prices between $214 and $329. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Luis Potosí.

On average, how many connections are available from San Diego to San Luis Potosí each day?

Every day, the San Diego to San Luis Potosí bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to San Luis Potosí take?

The fastest bus from San Diego to San Luis Potosí is offered by Greyhound US and takes 53h 0m. Bus tickets for this connection cost $232. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to San Luis Potosí?

The earliest bus arriving in San Luis Potosí from San Diego starts at 7:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to San Luis Potosí?

The latest bus trip departing from San Diego for San Luis Potosí starts at 7:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego San Luis Potosí route?

When traveling by bus from San Diego to San Luis Potosí, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and San Luis Potosí?

You can check all the direct connections between San Diego and San Luis Potosí by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Diego to San Luis Potosí bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego San Luis Potosí bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego San Luis Potosí bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to San Luis Potosí on your planned travel date.

How does CheckMyBus find the best bus deals from San Diego to San Luis Potosí?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 12 daily trips between San Diego and San Luis Potosí. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Diego to San Luis Potosí?

Prices and availability for 12 trips between San Diego and San Luis Potosí change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Diego to San Luis Potosí

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to San Luis Potosí

Here’s an overview of the most popular bus routes to San Diego and to San Luis Potosí. Simply click on the connection of your choice, and you will find all the details about your bus route!