Bus from Milan to Brindisi from $30

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Compare all timetables for the bus from Milan to Brindisi

Here is a selection of the cheapest bus trips from the schedule from Milan to Brindisi from various bus operators like Itabus, MarinoBus or FlixBus for the next days.
today
from $42
tomorrow
from $48
Wednesday
from $48
Thursday
from $55
Friday
from $44
Saturday
from $40
Sunday
from $30

Cheapest bus trips today

Prices are for one way and one person
  • Itabus
    15h 15m
    0
    8:10 PM
    Milan
    San Donato Bus Station
    11:25 AM
    Brindisi
    Tribunale Bus Stop
    0
    Itabus
    Premium Economy
    $42
  • Itabus
    18h 55m
    0
    12:35 PM
    Milan
    Lampugnano Bus Station
    7:30 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    Itabus
    Economy
    $48
  • MarinoBus
    13h 35m
    0
    6:50 PM
    Milan
    Lampugnano Bus Station
    8:25 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    MarinoBus
    Economy
    $76
  • MarinoBus
    13h 35m
    0
    6:50 PM
    Milan
    Lampugnano Bus Station
    8:25 AM
    Brindisi
    Tribunale Bus Stop
    0
    MarinoBus
    Economy
    $76
  • FlixBus
    13h 10m
    0
    10:25 PM
    Milan
    Lampugnano Bus Station
    11:35 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    FlixBus
    Economy
    $76
  • Did you know that if you travel from Milan to Brindisi via San Donato Milanese, you can save more than $-5? You will find the corresponding connections below.
    • 13h 50m
      Milan
      6 mi
      7:45 AM
      San Donato Milanese
      San Donato M3
      9:35 PM
      Brindisi
      Via Giuseppe Maria Galanti Bus Stop
      0 mi
      Premium Economy
      $47

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Itabus
    18h 5m
    0
    10:30 PM
    Milan
    Lampugnano Bus Station
    4:35 PM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    Itabus
    Premium Economy
    $48
  • Itabus
    19h 0m
    0
    9:35 PM
    Milan
    Lampugnano Bus Station
    4:35 PM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    Itabus
    Premium Economy
    $56
  • FlixBus
    13h 10m
    0
    10:25 PM
    Milan
    Lampugnano Bus Station
    11:35 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    FlixBus
    Economy
    $69
  • FlixBus
    12h 30m
    0
    11:05 PM
    Milan
    San Donato Bus Station
    11:35 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    FlixBus
    Economy
    $69
  • MarinoBus
    13h 35m
    0
    6:50 PM
    Milan
    Lampugnano Bus Station
    8:25 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    MarinoBus
    Economy
    $76
  • Did you know that if you travel from Milan to Brindisi via San Donato Milanese, you can save more than $31? You will find the corresponding connections below.
    • Save more than 65%
      18h 15m
      Milan
      6 mi
      10:20 PM
      San Donato Milanese
      San Donato M3
      4:35 PM
      Brindisi
      Via Giuseppe Maria Galanti Bus Stop
      0 mi
      Economy
      $17

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Itabus
    18h 5m
    0
    10:30 PM
    Milan
    Lampugnano Bus Station
    4:35 PM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    Itabus
    Premium Economy
    $48
  • Itabus
    18h 5m
    0
    10:30 PM
    Milan
    Lampugnano Bus Station
    4:35 PM
    Brindisi
    Tribunale Bus Stop
    0
    Itabus
    Premium Economy
    $53
  • MarinoBus
    13h 30m
    0
    8:40 AM
    Milan
    Lampugnano Bus Station
    10:10 PM
    Brindisi
    Tribunale Bus Stop
    0
    MarinoBus
    Economy
    $75
  • MarinoBus
    13h 30m
    0
    8:40 AM
    Milan
    Lampugnano Bus Station
    10:10 PM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    MarinoBus
    Economy
    $75
  • FlixBus
    13h 55m
    0
    8:10 PM
    Milan
    Lampugnano Bus Station
    10:05 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    FlixBus
    Economy
    $101
  • Did you know that if you travel from Milan to Brindisi via San Donato Milanese, you can save more than $-9? You will find the corresponding connections below.
    • 18h 15m
      Milan
      6 mi
      10:20 PM
      San Donato Milanese
      San Donato M3
      4:35 PM
      Brindisi
      Tribunale Bus Stop
      0 mi
      Economy
      $57

Cheapest bus trips Thursday

Prices are for one way and one person
  • Itabus
    18h 15m
    0
    11:45 PM
    Milan
    San Donato Bus Station
    6:00 PM
    Brindisi
    Tribunale Bus Stop
    0
    Itabus
    Premium Economy
    $55
  • Itabus
    18h 15m
    0
    10:20 PM
    Milan
    San Donato Bus Station
    4:35 PM
    Brindisi
    Tribunale Bus Stop
    0
    Itabus
    Economy
    $57
  • MarinoBus
    13h 30m
    0
    8:40 AM
    Milan
    Lampugnano Bus Station
    10:10 PM
    Brindisi
    Tribunale Bus Stop
    0
    MarinoBus
    Economy
    $75
  • MarinoBus
    13h 35m
    0
    6:50 PM
    Milan
    Lampugnano Bus Station
    8:25 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    MarinoBus
    Economy
    $79
  • FlixBus
    14h 20m
    0
    8:10 PM
    Milan
    Lampugnano Bus Station
    10:30 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    FlixBus
    Economy
    $116
  • Did you know that if you travel from Milan to Brindisi via San Donato Milanese, you can save more than $18? You will find the corresponding connections below.
    • Save more than 33%
      18h 15m
      Milan
      6 mi
      10:20 PM
      San Donato Milanese
      San Donato M3
      4:35 PM
      Brindisi
      Via Giuseppe Maria Galanti Bus Stop
      0 mi
      Premium Economy
      $37
  • Did you know that if you travel from Milan to Brindisi via Bologna, you can save more than $17? You can find the corresponding connections below.
    • Busbud
      13h 50m
      0
      7:45 AM
      Milan
      San Donato Bus Station
      10:15 AM
      Bologna
      Piazza XX Settembre Bus Station
      0
      Busbud
      Economy
      $3
      • Waiting Time 0h 5m
    • Busbud
      11h 15m
      0
      10:20 AM
      Bologna
      Piazza XX Settembre Bus Station
      9:35 PM
      Brindisi
      Via Giuseppe Maria Galanti Bus Stop
      0
      Busbud
      Premium Economy
      $35
    Travel time is 0h 20m longer, but you will save $17

Cheapest bus trips Friday

Prices are for one way and one person
  • Itabus
    17h 50m
    0
    12:10 AM
    Milan
    Lampugnano Bus Station
    6:00 PM
    Brindisi
    Tribunale Bus Stop
    0
    Itabus
    Premium Economy
    $44
  • Itabus
    19h 40m
    0
    12:35 PM
    Milan
    Lampugnano Bus Station
    8:15 AM
    Brindisi
    Tribunale Bus Stop
    0
    Itabus
    Premium Economy
    $46
  • MarinoBus
    13h 30m
    0
    8:40 AM
    Milan
    Lampugnano Bus Station
    10:10 PM
    Brindisi
    Tribunale Bus Stop
    0
    MarinoBus
    Economy
    $81
  • MarinoBus
    13h 30m
    0
    8:40 AM
    Milan
    Lampugnano Bus Station
    10:10 PM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    MarinoBus
    Economy
    $81
  • FlixBus
    13h 10m
    0
    10:25 PM
    Milan
    Lampugnano Bus Station
    11:35 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    FlixBus
    Economy
    $100
  • Did you know that if you travel from Milan to Brindisi via San Donato Milanese, you can save more than $-20? You will find the corresponding connections below.
    • 13h 50m
      Milan
      6 mi
      7:45 AM
      San Donato Milanese
      San Donato M3
      9:35 PM
      Brindisi
      Via Giuseppe Maria Galanti Bus Stop
      0 mi
      Premium Economy
      $64
  • Did you know that if you travel from Milan to Brindisi via Bologna, you can save more than $14? You can find the corresponding connections below.
    • Distribusion
      18h 55m
      0
      12:35 PM
      Milan
      Lampugnano Bus Station
      4:10 PM
      Bologna
      Piazza XX Settembre Bus Station
      0
      Distribusion
      Premium Economy
      $3
      • Waiting Time 1h 50m
    • Distribusion
      13h 30m
      0
      6:00 PM
      Bologna
      Piazza XX Settembre Bus Station
      7:30 AM
      Brindisi
      Tribunale Bus Stop
      0
      Distribusion
      Premium Economy
      $26
    Travel time is 5h 45m longer, but you will save $14

Cheapest bus trips Saturday

Prices are for one way and one person
  • Itabus
    18h 30m
    0
    1:00 PM
    Milan
    Lampugnano Bus Station
    7:30 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    Itabus
    Economy
    $40
  • Itabus
    19h 15m
    0
    1:00 PM
    Milan
    Lampugnano Bus Station
    8:15 AM
    Brindisi
    Tribunale Bus Stop
    0
    Itabus
    Premium Economy
    $41
  • MarinoBus
    13h 35m
    0
    6:50 PM
    Milan
    Lampugnano Bus Station
    8:25 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    MarinoBus
    Economy
    $68
  • MarinoBus
    13h 35m
    0
    6:50 PM
    Milan
    Lampugnano Bus Station
    8:25 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    MarinoBus
    Economy
    $74
  • FlixBus
    13h 10m
    0
    10:25 PM
    Milan
    Lampugnano Bus Station
    11:35 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    FlixBus
    Economy
    $74
  • Did you know that if you travel from Milan to Brindisi via San Donato Milanese, you can save more than $3? You will find the corresponding connections below.
    • Save more than 8%
      13h 50m
      Milan
      6 mi
      7:45 AM
      San Donato Milanese
      San Donato M3
      9:35 PM
      Brindisi
      Via Giuseppe Maria Galanti Bus Stop
      0 mi
      Premium Economy
      $37
  • Did you know that if you travel from Milan to Brindisi via Bologna, you can save more than $10? You can find the corresponding connections below.
    • Distribusion
      18h 55m
      0
      12:35 PM
      Milan
      Lampugnano Bus Station
      4:10 PM
      Bologna
      Piazza XX Settembre Bus Station
      0
      Distribusion
      Premium Economy
      $3
      • Waiting Time 1h 50m
    • Distribusion
      13h 30m
      0
      6:00 PM
      Bologna
      Piazza XX Settembre Bus Station
      7:30 AM
      Brindisi
      Tribunale Bus Stop
      0
      Distribusion
      Premium Economy
      $26
    Travel time is 5h 45m longer, but you will save $10

Cheapest bus trips Sunday

Prices are for one way and one person
  • Itabus
    15h 15m
    0
    8:10 PM
    Milan
    San Donato Bus Station
    11:25 AM
    Brindisi
    Tribunale Bus Stop
    0
    Itabus
    Premium Economy
    $30
  • Itabus
    17h 5m
    0
    12:55 AM
    Milan
    San Donato Bus Station
    6:00 PM
    Brindisi
    Tribunale Bus Stop
    0
    Itabus
    Premium Economy
    $40
  • FlixBus
    13h 10m
    0
    10:25 PM
    Milan
    Lampugnano Bus Station
    11:35 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    FlixBus
    Economy
    $71
  • FlixBus
    12h 30m
    0
    11:05 PM
    Milan
    San Donato Bus Station
    11:35 AM
    Brindisi
    Via Giuseppe Maria Galanti Bus Stop
    0
    FlixBus
    Economy
    $71
  • MarinoBus
    13h 35m
    0
    6:50 PM
    Milan
    Lampugnano Bus Station
    8:25 AM
    Brindisi
    Tribunale Bus Stop
    0
    MarinoBus
    Economy
    $76
  • Did you know that if you travel from Milan to Brindisi via San Donato Milanese, you can save more than $-5? You will find the corresponding connections below.
    • 13h 50m
      Milan
      6 mi
      7:45 AM
      San Donato Milanese
      San Donato M3
      9:35 PM
      Brindisi
      Via Giuseppe Maria Galanti Bus Stop
      0 mi
      Premium Economy
      $35

Frequency of bus connections between Milan and Brindisi

See here how frequent the connections between Milan and Brindisi are, during different times and days of the week.
Saturday is the busiest day, with more than 100 daily buses from Milan to Brindisi. Tuesday has instead the fewest connections, with only 31 daily coaches between Milan and Brindisi.
The busiest time of the day is the Evening, with 203 buses from Milan to Brindisi, while Night sees the fewest connections between Milan and Brindisi, with 36 offers.

Facts about the bus from Milan to Brindisi

Compare all providers like Itabus, MarinoBus and FlixBus that travel 53 times every day by bus from Milan to Brindisi in one click! Book your bus ticket from Milan to Brindisi starting from $30!

Cheapest Bus $30
Fastest Bus 12h 30m
Earliest Bus 12:10 AM
Latest Bus 11:45 PM
Daily Bus Routes 53 Ø
Distance 553.7 miles
Bus Companies Itabus, MarinoBus and FlixBus

Cheapest bus connections from Milan to Brindisi

Every day, 53 buses from 3 bus companies leave Milan for Brindisi: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/23/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
Monday 06/23
$69
Tuesday 06/24
$72
Wednesday 06/25
$36
Thursday 06/26
$64
Friday 06/27
$44
Saturday 06/28
$74
Sunday 06/29
$71
Monday 06/30
$31
Tuesday 07/01
$33
Wednesday 07/02
$29
Thursday 07/03
$43
Friday 07/04
$46
Saturday 07/05
$48
Sunday 07/06
$45
Monday 07/07
$30
Tuesday 07/08
$33
Wednesday 07/09
$33
Thursday 07/10
$83
Friday 07/11
$38
Saturday 07/12
$30
Sunday 07/13
$40
Monday 07/14
$30
Tuesday 07/15
$47
Wednesday 07/16
$38
Thursday 07/17
$72
Friday 07/18
$53
Saturday 07/19

The cheapest time to travel from Milan to Brindisi

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Brindisi, for the next 30 days.
With a price starting from $30, Sunday is the cheapest day for a bus from Milan to Brindisi. Thursday instead is the most expensive day with prices starting from $55.
Evening is the cheapest day time for bus tickets from Milan to Brindisi, with $30. Morning is the most expensive time of the day with prices starting from $69.

How to save money travelling from Milan to Brindisi

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Brindisi in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Brindisi, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Brindisi are also emptier.

All bus stations and stops in Milan and Brindisi

In the map below, you can see where to find all bus stations in Milan and Brindisi.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Brindisi? Compare all modes of transports from Milan to Brindisi.

Service and Comfort on the bus from Milan to Brindisi

Want to know which seat classes are available on the buses from Milan to Brindisi? Or which bus companies serve the route Milan to Brindisi? Below you will find answers to your questions.

FAQs about the Milan to Brindisi bus

How much does a Milan Brindisi bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $30 and takes 15h 15m to reach Brindisi. Compare offers to save money!

How much could I save by comparing buses from Milan to Brindisi?

This route is offered by 3 companies with a range of ticket prices between $30 and $156. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brindisi.

On average, how many connections are available from Milan to Brindisi each day?

Every day, the Milan to Brindisi bus route is served by approximately 53 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milan to Brindisi take?

The fastest bus from Milan to Brindisi is offered by FlixBus and takes 12h 30m. Bus tickets for this connection cost $76. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milan to Brindisi?

The earliest bus arriving in Brindisi from Milan starts at 12:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milan to Brindisi?

The latest bus trip departing from Milan for Brindisi starts at 11:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milan Brindisi route?

When traveling by bus from Milan to Brindisi, passengers can travel with Itabus, MarinoBus and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milan and Brindisi?

You can check all the direct connections between Milan and Brindisi by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus, MarinoBus and FlixBus.

What can I take with me on the Milan to Brindisi bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milan Brindisi bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Brindisi bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Brindisi on your planned travel date.

Available seat classes which are offered on the bus route Milan to Brindisi

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Milan and to Brindisi

Here’s an overview of the most popular bus routes to Milan and to Brindisi. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Milan from Chamonix Bus to Milan from Chamonix
Bus to Milan from Bolzano Bus to Milan from Bolzano
Bus to Milan from Ljubljana Bus to Milan from Ljubljana
Bus Frankfurt am Main - Milan Bus Frankfurt am Main - Milan
From Ostuni to Brindisi bus From Ostuni to Brindisi bus
Bus Otranto to Brindisi Bus Otranto to Brindisi
Bus Gallipoli - Brindisi Bus Gallipoli - Brindisi
Bus from Matera to Brindisi Bus from Matera to Brindisi
Popular Airport Shuttles to Milan and to Brindisi
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