Bus Milan to Brindisi: Compare prices and save money

Compare all timetables for the bus from Milan to Brindisi

Here is a selection of the cheapest bus trips from the schedule from Milan to Brindisi from various bus operators like FlixBus, MarinoBus or Itabus for the next days.

today

$38

tomorrow

$31

Saturday

$38

Sunday

$38

Monday

$35

Tuesday

$38

Wednesday

$32

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
MarinoBus	13h 20m	8:25 PM	Milan	Lampugnano Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 11/5/2026 8:25:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/6/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 13h 20m
MarinoBus	12h 40m	9:05 PM	Milan	San Donato Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from San Donato Bus Station, Milan (Italy) at 11/5/2026 9:05:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/6/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 12h 40m
Itabus	19h 55m	8:25 PM	Milan	Lampugnano Bus Station	4:20 PM	Brindisi	Tribunale Bus Stop	Premium Economy	$45	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 11/5/2026 8:25:00 PM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/6/2026 4:20:00 PM. 50 Premium Economy ticket for $45 per person are available. Travel duration is 19h 55m
Itabus	17h 50m	10:30 PM	Milan	Lampugnano Bus Station	4:20 PM	Brindisi	Tribunale Bus Stop	Premium Economy	$51	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 11/5/2026 10:30:00 PM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/6/2026 4:20:00 PM. 50 Premium Economy ticket for $51 per person are available. Travel duration is 17h 50m
FlixBus	17h 55m	10:45 PM	Milan	Lampugnano Bus Station	4:40 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$71	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/5/2026 10:45:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/6/2026 4:40:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 17h 55m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	19h 15m	11:10 PM	Milan	San Donato Bus Station	6:25 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$31	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 11/6/2026 11:10:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/7/2026 6:25:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 19h 15m
Itabus	19h 45m	10:40 AM	Milan	Lampugnano Bus Station	6:25 AM	Brindisi	Tribunale Bus Stop	Premium Economy	$39	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 11/6/2026 10:40:00 AM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/7/2026 6:25:00 AM. 50 Premium Economy ticket for $39 per person are available. Travel duration is 19h 45m
Itabus	17h 50m	12:35 PM	Milan	San Donato Bus Station	6:25 AM	Brindisi	Tribunale Bus Stop	Premium Economy	$42	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 11/6/2026 12:35:00 PM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/7/2026 6:25:00 AM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 17h 50m
MarinoBus	13h 45m	8:25 AM	Milan	Lampugnano Bus Station	10:10 PM	Brindisi	Tribunale Bus Stop	Economy	$47	A Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 11/6/2026 8:25:00 AM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/6/2026 10:10:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 13h 45m
MarinoBus	13h 0m	9:10 AM	Milan	San Donato Bus Station	10:10 PM	Brindisi	Tribunale Bus Stop	Economy	$47	A Bus from MarinoBus goes from San Donato Bus Station, Milan (Italy) at 11/6/2026 9:10:00 AM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/6/2026 10:10:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 13h 0m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
MarinoBus	13h 20m	8:25 PM	Milan	Lampugnano Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 11/7/2026 8:25:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/8/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 13h 20m
MarinoBus	12h 40m	9:05 PM	Milan	San Donato Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from San Donato Bus Station, Milan (Italy) at 11/7/2026 9:05:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/8/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 12h 40m
Itabus	17h 50m	10:30 PM	Milan	Lampugnano Bus Station	4:20 PM	Brindisi	Tribunale Bus Stop	Premium Economy	$42	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 11/7/2026 10:30:00 PM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/8/2026 4:20:00 PM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 17h 50m
Itabus	17h 50m	12:35 PM	Milan	San Donato Bus Station	6:25 AM	Brindisi	Tribunale Bus Stop	Premium Economy	$42	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 11/7/2026 12:35:00 PM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/8/2026 6:25:00 AM. 50 Premium Economy ticket for $42 per person are available. Travel duration is 17h 50m
FlixBus	16h 5m	9:50 PM	Milan	Lampugnano Bus Station	1:55 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$43	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/7/2026 9:50:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/8/2026 1:55:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 16h 5m

Did you know that if you travel from Milan to Brindisi via Bologna, you can save more than $5? You can find the corresponding connections below.
- FlixBus
  
  18h 0m
  
  0
  
  2:25 AM
  
  Milan
  Lampugnano Bus Station
  
  5:05 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/9/2026 2:25:00 AM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 11/9/2026 5:05:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 40m
- Itabus
  
  13h 25m
  
  0
  
  7:00 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  8:25 PM
  
  Brindisi
  Via Giuseppe Maria Galanti Bus Stop
  
  0
  
  Economy
  
  $19
  
  A Bus from Itabus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 11/9/2026 7:00:00 AM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/9/2026 8:25:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 13h 25m
Travel time is 5h 20m longer, but you will save $5

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
MarinoBus	13h 20m	8:25 PM	Milan	Lampugnano Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 11/8/2026 8:25:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/9/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 13h 20m
MarinoBus	12h 40m	9:05 PM	Milan	San Donato Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from San Donato Bus Station, Milan (Italy) at 11/8/2026 9:05:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/9/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 12h 40m
Itabus	17h 50m	12:35 PM	Milan	San Donato Bus Station	6:25 AM	Brindisi	Tribunale Bus Stop	Premium Economy	$51	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 11/8/2026 12:35:00 PM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/9/2026 6:25:00 AM. 50 Premium Economy ticket for $51 per person are available. Travel duration is 17h 50m
Itabus	17h 50m	10:30 PM	Milan	Lampugnano Bus Station	4:20 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Premium Economy	$53	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 11/8/2026 10:30:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/9/2026 4:20:00 PM. 50 Premium Economy ticket for $53 per person are available. Travel duration is 17h 50m
FlixBus	16h 5m	9:50 PM	Milan	Lampugnano Bus Station	1:55 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$71	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/8/2026 9:50:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/9/2026 1:55:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 16h 5m

Did you know that if you travel from Milan to Brindisi via Bologna, you can save more than $5? You can find the corresponding connections below.
- FlixBus
  
  18h 0m
  
  0
  
  2:25 AM
  
  Milan
  Lampugnano Bus Station
  
  5:05 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/9/2026 2:25:00 AM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 11/9/2026 5:05:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 40m
- Itabus
  
  13h 25m
  
  0
  
  7:00 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  8:25 PM
  
  Brindisi
  Via Giuseppe Maria Galanti Bus Stop
  
  0
  
  Economy
  
  $19
  
  A Bus from Itabus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 11/9/2026 7:00:00 AM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/9/2026 8:25:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 13h 25m
Travel time is 5h 20m longer, but you will save $5

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	19h 45m	10:40 AM	Milan	Lampugnano Bus Station	6:25 AM	Brindisi	Tribunale Bus Stop	Premium Economy	$35	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 11/9/2026 10:40:00 AM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/10/2026 6:25:00 AM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 19h 45m
MarinoBus	13h 20m	8:25 PM	Milan	Lampugnano Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 11/9/2026 8:25:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/10/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 13h 20m
MarinoBus	12h 40m	9:05 PM	Milan	San Donato Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from San Donato Bus Station, Milan (Italy) at 11/9/2026 9:05:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/10/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 12h 40m
Itabus	17h 50m	12:35 PM	Milan	San Donato Bus Station	6:25 AM	Brindisi	Tribunale Bus Stop	Premium Economy	$39	A Bus from Itabus goes from San Donato Bus Station, Milan (Italy) at 11/9/2026 12:35:00 PM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/10/2026 6:25:00 AM. 50 Premium Economy ticket for $39 per person are available. Travel duration is 17h 50m
FlixBus	18h 35m	11:50 PM	Milan	San Donato Bus Station	6:25 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$43	A Bus from FlixBus goes from San Donato Bus Station, Milan (Italy) at 11/9/2026 11:50:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/10/2026 6:25:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 18h 35m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
MarinoBus	13h 20m	8:25 PM	Milan	Lampugnano Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 11/10/2026 8:25:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/11/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 13h 20m
MarinoBus	12h 40m	9:05 PM	Milan	San Donato Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from San Donato Bus Station, Milan (Italy) at 11/10/2026 9:05:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/11/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 12h 40m
FlixBus	16h 5m	9:50 PM	Milan	Lampugnano Bus Station	1:55 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$39	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/10/2026 9:50:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/11/2026 1:55:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 16h 5m
FlixBus	17h 55m	10:45 PM	Milan	Lampugnano Bus Station	4:40 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$44	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/10/2026 10:45:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/11/2026 4:40:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 17h 55m
Itabus	19h 45m	10:40 AM	Milan	Lampugnano Bus Station	6:25 AM	Brindisi	Tribunale Bus Stop	Premium Economy	$44	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 11/10/2026 10:40:00 AM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/11/2026 6:25:00 AM. 50 Premium Economy ticket for $44 per person are available. Travel duration is 19h 45m

Did you know that if you travel from Milan to Brindisi via Bologna, you can save more than $5? You can find the corresponding connections below.
- FlixBus
  
  18h 0m
  
  0
  
  2:25 AM
  
  Milan
  Lampugnano Bus Station
  
  5:05 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/9/2026 2:25:00 AM to Piazza XX Settembre Bus Station, Bologna (Italy) arriving at 11/9/2026 5:05:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 40m
- Itabus
  
  13h 25m
  
  0
  
  7:00 AM
  
  Bologna
  Piazza XX Settembre Bus Station
  
  8:25 PM
  
  Brindisi
  Via Giuseppe Maria Galanti Bus Stop
  
  0
  
  Economy
  
  $19
  
  A Bus from Itabus goes from Piazza XX Settembre Bus Station, Bologna (Italy) at 11/9/2026 7:00:00 AM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/9/2026 8:25:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 13h 25m
Travel time is 5h 20m longer, but you will save $5

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	19h 45m	10:40 AM	Milan	Lampugnano Bus Station	6:25 AM	Brindisi	Tribunale Bus Stop	Premium Economy	$32	A Bus from Itabus goes from Lampugnano Bus Station, Milan (Italy) at 11/11/2026 10:40:00 AM to Tribunale Bus Stop, Brindisi (Italy) arriving at 11/12/2026 6:25:00 AM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 19h 45m
MarinoBus	13h 20m	8:25 PM	Milan	Lampugnano Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from Lampugnano Bus Station, Milan (Italy) at 11/11/2026 8:25:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/12/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 13h 20m
MarinoBus	12h 40m	9:05 PM	Milan	San Donato Bus Station	9:45 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$38	A Bus from MarinoBus goes from San Donato Bus Station, Milan (Italy) at 11/11/2026 9:05:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/12/2026 9:45:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 12h 40m
FlixBus	17h 45m	12:25 PM	Milan	Lampugnano Bus Station	6:10 AM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$50	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/11/2026 12:25:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/12/2026 6:10:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 17h 45m
FlixBus	16h 5m	9:50 PM	Milan	Lampugnano Bus Station	1:55 PM	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	$51	A Bus from FlixBus goes from Lampugnano Bus Station, Milan (Italy) at 11/11/2026 9:50:00 PM to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 11/12/2026 1:55:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 16h 5m

Best Price Offer: The price for the cheapest bus from Milan to Brindisi is $21 on 11/21/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Milan and Brindisi

See here how frequent the connections between Milan and Brindisi are, during different times and days of the week.

Friday is the busiest day, with more than 56 daily buses from Milan to Brindisi. Wednesday has instead the fewest connections, with only 28 daily coaches between Milan and Brindisi.

The busiest time of the day is the Evening, with 202 buses from Milan to Brindisi, while Night sees the fewest connections between Milan and Brindisi, with 12 offers.

Facts about the bus from Milan to Brindisi

Compare all providers like FlixBus, MarinoBus and Itabus that travel 44 times every day by bus from Milan to Brindisi in one click! Book your bus ticket from Milan to Brindisi starting from $21!

Cheapest Bus	$21
Fastest Bus	12h 40m
Earliest Bus	7:25 AM
Latest Bus	11:50 PM
Daily Bus Routes	44 Ø
Distance	553.7 miles
Bus Companies	FlixBus, MarinoBus and Itabus

Cheapest bus connections from Milan to Brindisi

Every day, 44 buses from 3 bus companies leave Milan for Brindisi: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 11/05/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/01

Monday 11/02

Tuesday 11/03

Wednesday 11/04

Thursday 11/05

$45

Friday 11/06

$39

Saturday 11/07

$76

Sunday 11/08

$40

Monday 11/09

$36

Tuesday 11/10

$38

Wednesday 11/11

$61

Thursday 11/12

$42

Friday 11/13

$39

Saturday 11/14

$32

Sunday 11/15

$36

Monday 11/16

$37

Tuesday 11/17

$35

Wednesday 11/18

$35

Thursday 11/19

$43

Friday 11/20

$37

Saturday 11/21

$21

Sunday 11/22

$37

Monday 11/23

$34

Tuesday 11/24

$35

Wednesday 11/25

$40

Thursday 11/26

$28

Friday 11/27

$76

Saturday 11/28

The cheapest time to travel from Milan to Brindisi

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Brindisi, for the next 30 days.

With a price starting from $21, Saturday is the cheapest day for a bus from Milan to Brindisi. Tuesday instead is the most expensive day with prices starting from $35.

Night is the cheapest day time for bus tickets from Milan to Brindisi, with $21. Afternoon is the most expensive time of the day with prices starting from $39.

How to save money travelling from Milan to Brindisi

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Brindisi in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Brindisi, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Brindisi are also emptier.

Beloved bus companies from Milan to Brindisi

These are the most booked bus companies between Milan to Brindisi from our users.

FlixBus from Milan to Brindisi

Here you will find the key facts about the FlixBus bus route Milan to Brindisi:

Cheapest Price	$28
Fastest Bus	13h 0m
Earliest Bus	7:25 AM
Last Bus	11:50 PM
Daily Connections	18 Ø
Found on	11/5/2026

All bus stations and stops in Milan and Brindisi

In the map below, you can see where to find all bus stations in Milan and Brindisi.

Lampugnano Bus Station

Via Giulio Natta Lampugnano

Rogoredo Bus Station

Via Cassinis Giovanni Battista 76

San Donato Bus Station

Via Giuseppe Impastato 25

Central Station - Piazza Luigi di Savoia

Piazza Duca D'Aosta 16

Duomo Bus Stop

Piazza del Duomo

Via Giuseppe Maria Galanti Bus Stop

Via Giuseppe Maria Galanti 8

Central Bus Station

Port

Costa Morena Bus Stop

Viale Arno Bus Stop

Viale Arno

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Brindisi? Compare all modes of transports from Milan to Brindisi.

Service and Comfort on the bus from Milan to Brindisi

Want to know which seat classes are available on the buses from Milan to Brindisi? Or which bus companies serve the route Milan to Brindisi? Below you will find answers to your questions.

FAQs about the Milan to Brindisi bus

How much does a Milan Brindisi bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $21 and takes 19h 15m to reach Brindisi. Compare offers to save money!

How much could I save by comparing buses from Milan to Brindisi?

This route is offered by 3 companies with a range of ticket prices between $21 and $146. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brindisi.

On average, how many connections are available from Milan to Brindisi each day?

Every day, the Milan to Brindisi bus route is served by approximately 44 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milan to Brindisi take?

The fastest bus from Milan to Brindisi is offered by MarinoBus and takes 12h 40m. Bus tickets for this connection cost $38. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milan to Brindisi?

The earliest bus arriving in Brindisi from Milan starts at 7:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milan to Brindisi?

The latest bus trip departing from Milan for Brindisi starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milan Brindisi route?

When traveling by bus from Milan to Brindisi, passengers can travel with FlixBus, MarinoBus and Itabus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milan and Brindisi?

You can check all the direct connections between Milan and Brindisi by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, MarinoBus and Itabus.

What can I take with me on the Milan to Brindisi bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milan Brindisi bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Brindisi bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Brindisi on your planned travel date.

How does CheckMyBus find the best bus deals from Milan to Brindisi?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 44 daily trips between Milan and Brindisi. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milan to Brindisi?

Prices and availability for 44 trips between Milan and Brindisi change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milan to Brindisi

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Milan and to Brindisi

Here’s an overview of the most popular bus routes to Milan and to Brindisi. Simply click on the connection of your choice, and you will find all the details about your bus route!