Bus Mobile, AL to Chicago: Compare prices and save money

Compare all timetables for the bus from Mobile, AL to Chicago

Here is a selection of the cheapest bus trips from the schedule from Mobile, AL to Chicago from various bus operators like Greyhound US for the next days.

today

$139

tomorrow

$134

Thursday

Friday

$135

Saturday

$159

Sunday

$180

Monday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	26h 20m	7:30 AM	Mobile, AL	Greyhound Bus Station	9:50 AM	Chicago	95th Red Line Station	Economy	$139	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/16/2025 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/17/2025 9:50:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 26h 20m
Greyhound US	26h 40m	3:55 PM	Mobile, AL	Greyhound Bus Station	6:35 PM	Chicago	95th Red Line Station	Economy	$139	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/16/2025 3:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/17/2025 6:35:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 26h 40m
Greyhound US	24h 30m	7:30 AM	Mobile, AL	Greyhound Bus Station	8:00 AM	Chicago	Union Station	Economy	$145	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/16/2025 7:30:00 AM to Union Station, Chicago (USA) arriving at 12/17/2025 8:00:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 24h 30m
Greyhound US	26h 30m	11:40 AM	Mobile, AL	Greyhound Bus Station	2:10 PM	Chicago	Union Station	Economy	$145	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/16/2025 11:40:00 AM to Union Station, Chicago (USA) arriving at 12/17/2025 2:10:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 26h 30m
Greyhound US	24h 55m	7:30 AM	Mobile, AL	Greyhound Bus Station	8:25 AM	Chicago	Downtown Bus Station	Economy	$145	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/16/2025 7:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/17/2025 8:25:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 24h 55m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 45m	12:05 AM	Mobile, AL	Greyhound Bus Station	11:50 PM	Chicago	95th Red Line Station	Economy	$134	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/17/2025 12:05:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/17/2025 11:50:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 23h 45m
Greyhound US	23h 25m	11:40 AM	Mobile, AL	Greyhound Bus Station	11:05 AM	Chicago	95th Red Line Station	Economy	$134	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/17/2025 11:40:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/18/2025 11:05:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 23h 25m
Greyhound US	24h 0m	3:55 PM	Mobile, AL	Greyhound Bus Station	3:55 PM	Chicago	95th Red Line Station	Economy	$134	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/17/2025 3:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/18/2025 3:55:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 24h 0m
Greyhound US	29h 40m	2:40 AM	Mobile, AL	Greyhound Bus Station	8:20 AM	Chicago	95th Red Line Station	Economy	$135	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/17/2025 2:40:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/18/2025 8:20:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 29h 40m
Greyhound US	26h 20m	7:30 AM	Mobile, AL	Greyhound Bus Station	9:50 AM	Chicago	95th Red Line Station	Economy	$140	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/17/2025 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/18/2025 9:50:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 26h 20m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 30m	2:40 AM	Mobile, AL	Greyhound Bus Station	4:10 AM	Chicago	Downtown Bus Station	Economy	$135	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/19/2025 2:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 4:10:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 25h 30m
Greyhound US	24h 5m	12:05 AM	Mobile, AL	Greyhound Bus Station	12:10 AM	Chicago	Downtown Bus Station	Economy	$149	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/19/2025 12:05:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 12:10:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 24h 5m
Greyhound US	23h 20m	3:55 PM	Mobile, AL	Greyhound Bus Station	3:15 PM	Chicago	Downtown Bus Station	Economy	$159	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/19/2025 3:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 3:15:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 23h 20m
Greyhound US	24h 55m	7:30 AM	Mobile, AL	Greyhound Bus Station	8:25 AM	Chicago	Downtown Bus Station	Economy	$162	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/19/2025 7:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/20/2025 8:25:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 24h 55m
Greyhound US	24h 30m	7:30 AM	Mobile, AL	Greyhound Bus Station	8:00 AM	Chicago	Union Station	Economy	$162	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/19/2025 7:30:00 AM to Union Station, Chicago (USA) arriving at 12/20/2025 8:00:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 24h 30m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	26h 40m	2:40 AM	Mobile, AL	Greyhound Bus Station	5:20 AM	Chicago	95th Red Line Station	Economy	$159	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/20/2025 2:40:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/21/2025 5:20:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 26h 40m
Greyhound US	26h 20m	7:30 AM	Mobile, AL	Greyhound Bus Station	9:50 AM	Chicago	95th Red Line Station	Economy	$159	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/20/2025 7:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/21/2025 9:50:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 26h 20m
Greyhound US	24h 0m	3:55 PM	Mobile, AL	Greyhound Bus Station	3:55 PM	Chicago	95th Red Line Station	Economy	$159	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/20/2025 3:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 12/21/2025 3:55:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 24h 0m
Greyhound US	23h 45m	12:05 AM	Mobile, AL	Greyhound Bus Station	11:50 PM	Chicago	95th Red Line Station	Economy	$160	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/20/2025 12:05:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/20/2025 11:50:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 23h 45m
Greyhound US	23h 25m	11:40 AM	Mobile, AL	Greyhound Bus Station	11:05 AM	Chicago	95th Red Line Station	Economy	$162	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/20/2025 11:40:00 AM to 95th Red Line Station, Chicago (USA) arriving at 12/21/2025 11:05:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 23h 25m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 30m	2:40 AM	Mobile, AL	Greyhound Bus Station	4:10 AM	Chicago	Downtown Bus Station	Economy	$180	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/21/2025 2:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/22/2025 4:10:00 AM. 50 Economy ticket for $180 per person are available. Travel duration is 25h 30m
Greyhound US	23h 20m	3:55 PM	Mobile, AL	Greyhound Bus Station	3:15 PM	Chicago	Downtown Bus Station	Economy	$182	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/21/2025 3:55:00 PM to Downtown Bus Station, Chicago (USA) arriving at 12/22/2025 3:15:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 23h 20m
Greyhound US	26h 30m	11:40 AM	Mobile, AL	Greyhound Bus Station	2:10 PM	Chicago	Union Station	Economy	$187	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/21/2025 11:40:00 AM to Union Station, Chicago (USA) arriving at 12/22/2025 2:10:00 PM. 50 Economy ticket for $187 per person are available. Travel duration is 26h 30m
Greyhound US	24h 55m	7:30 AM	Mobile, AL	Greyhound Bus Station	8:25 AM	Chicago	Downtown Bus Station	Economy	$189	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/21/2025 7:30:00 AM to Downtown Bus Station, Chicago (USA) arriving at 12/22/2025 8:25:00 AM. 50 Economy ticket for $189 per person are available. Travel duration is 24h 55m
Greyhound US	24h 30m	7:30 AM	Mobile, AL	Greyhound Bus Station	8:00 AM	Chicago	Union Station	Economy	$189	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/21/2025 7:30:00 AM to Union Station, Chicago (USA) arriving at 12/22/2025 8:00:00 AM. 50 Economy ticket for $189 per person are available. Travel duration is 24h 30m

Best Price Offer: The price for the cheapest bus from Mobile, AL to Chicago is $131 on 1/7/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Mobile, AL and Chicago

See here how frequent the connections between Mobile, AL and Chicago are, during different times and days of the week.

Wednesday is the busiest day, with more than 24 daily buses from Mobile, AL to Chicago. Sunday has instead the fewest connections, with only 7 daily coaches between Mobile, AL and Chicago.

The busiest time of the day is the Morning, with 38 buses from Mobile, AL to Chicago, while Afternoon sees the fewest connections between Mobile, AL and Chicago, with 12 offers.

Facts about the bus from Mobile, AL to Chicago

Compare all providers like Greyhound US that travel 14 times every day by bus from Mobile, AL to Chicago in one click! Book your bus ticket from Mobile, AL to Chicago starting from $131!

Cheapest Bus	$131
Fastest Bus	22h 15m
Earliest Bus	7:30 AM
Latest Bus	3:55 PM
Daily Bus Routes	14 Ø
Distance	772.7 miles
Bus Companies	Greyhound US

Cheapest bus connections from Mobile, AL to Chicago

Every day, 14 buses from 1 bus companies leave Mobile, AL for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/16/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

$138

Wednesday 12/17

$135

Thursday 12/18

Friday 12/19

$135

Saturday 12/20

$161

Sunday 12/21

$180

Monday 12/22

Tuesday 12/23

$158

Wednesday 12/24

$145

Thursday 12/25

$139

Friday 12/26

$143

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

$131

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Mobile, AL to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Mobile, AL to Chicago, for the next 30 days.

With a price starting from $119, Saturday is the cheapest day for a bus from Mobile, AL to Chicago. Sunday instead is the most expensive day with prices starting from $180.

Night is the cheapest day time for bus tickets from Mobile, AL to Chicago, with $119. Morning is the most expensive time of the day with prices starting from $134.

How to save money travelling from Mobile, AL to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mobile, AL to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mobile, AL to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mobile, AL to Chicago are also emptier.

All bus stations and stops in Mobile, AL and Chicago

In the map below, you can see where to find all bus stations in Mobile, AL and Chicago.

GM&O Transit Center

Beauregard St 110

I-65 Hwy Exit 4 McDonald's

Springdale Blvd 2

Greyhound Bus Station

Government Blvd 1545

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Mobile, AL to Chicago

Want to know which seat classes are available on the buses from Mobile, AL to Chicago? Or which bus companies serve the route Mobile, AL to Chicago? Below you will find answers to your questions.

FAQs about the Mobile, AL to Chicago bus

How much does a Mobile, AL Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $131 and takes 23h 45m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Mobile, AL to Chicago?

This route is offered by 1 companies with a range of ticket prices between $131 and $244. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Mobile, AL to Chicago each day?

Every day, the Mobile, AL to Chicago bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mobile, AL to Chicago take?

The fastest bus from Mobile, AL to Chicago is offered by Greyhound US and takes 22h 15m. Bus tickets for this connection cost $166. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mobile, AL to Chicago?

The earliest bus arriving in Chicago from Mobile, AL starts at 7:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mobile, AL to Chicago?

The latest bus trip departing from Mobile, AL for Chicago starts at 3:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mobile, AL Chicago route?

When traveling by bus from Mobile, AL to Chicago, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mobile, AL and Chicago?

You can check all the direct connections between Mobile, AL and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mobile, AL to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mobile, AL Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mobile, AL Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mobile, AL to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Mobile, AL to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 14 daily trips between Mobile, AL and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mobile, AL to Chicago?

Prices and availability for 14 trips between Mobile, AL and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mobile, AL to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mobile, AL and to Chicago

Here’s an overview of the most popular bus routes to Mobile, AL and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!