Bus Mobile, AL to Tupelo, MS - Compare all Companies

Compare all timetables for the bus from Mobile, AL to Tupelo, MS

Here is a selection of the cheapest bus trips from the schedule from Mobile, AL to Tupelo, MS from various bus operators like Greyhound US for the next days.

today

tomorrow

$76

Wednesday

Thursday

$67

Friday

Saturday

$64

Sunday

$81

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	9h 45m	11:40 AM	Mobile, AL	Greyhound Bus Station	9:25 PM	Tupelo, MS	Bus Stop		Economy	$76	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 4/21/2026 11:40:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/21/2026 9:25:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 9h 45m
	Greyhound US	13h 15m	4:10 PM	Mobile, AL	Greyhound Bus Station	5:25 AM	Tupelo, MS	Bus Stop		Economy	$76	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 4/21/2026 4:10:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 4/22/2026 5:25:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 13h 15m

Did you know that if you travel from Mobile, AL to Tupelo, MS via Birmingham, AL, you can save more than $11? You can find the corresponding connections below.
- Greyhound US
  
  12h 55m
  
  0
  
  8:30 AM
  
  Mobile, AL
  Greyhound Bus Station
  
  4:00 PM
  
  Birmingham, AL
  MAX Central Station
  
  0
  
  Economy
  
  $40
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 4/22/2026 8:30:00 AM to MAX Central Station, Birmingham, AL (USA) arriving at 4/22/2026 4:00:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 30m
- Greyhound US
  
  2h 45m
  
  0
  
  6:40 PM
  
  Birmingham, AL
  MAX Central Station
  
  9:25 PM
  
  Tupelo, MS
  Bus Stop
  
  0
  
  Economy
  
  $25
  
  A Bus from Greyhound US goes from MAX Central Station, Birmingham, AL (USA) at 4/22/2026 6:40:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 4/22/2026 9:25:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 2h 45m
Travel time is 3h 10m longer, but you will save $11

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	9h 45m	11:40 AM	Mobile, AL	Greyhound Bus Station	9:25 PM	Tupelo, MS	Bus Stop		Economy	$67	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 4/23/2026 11:40:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/23/2026 9:25:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 9h 45m
	Greyhound US	13h 15m	4:10 PM	Mobile, AL	Greyhound Bus Station	5:25 AM	Tupelo, MS	Bus Stop		Economy	$67	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 4/23/2026 4:10:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 4/24/2026 5:25:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 13h 15m

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	13h 15m	4:10 PM	Mobile, AL	Greyhound Bus Station	5:25 AM	Tupelo, MS	Bus Stop		Economy	$64	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 4/25/2026 4:10:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 4/26/2026 5:25:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 13h 15m
	Greyhound US	9h 45m	11:40 AM	Mobile, AL	Greyhound Bus Station	9:25 PM	Tupelo, MS	Bus Stop		Economy	$65	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 4/25/2026 11:40:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/25/2026 9:25:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 9h 45m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	9h 45m	11:40 AM	Mobile, AL	Greyhound Bus Station	9:25 PM	Tupelo, MS	Bus Stop		Economy	$81	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 4/26/2026 11:40:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/26/2026 9:25:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 9h 45m
	Greyhound US	13h 15m	4:10 PM	Mobile, AL	Greyhound Bus Station	5:25 AM	Tupelo, MS	Bus Stop		Economy	$83	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 4/26/2026 4:10:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 4/27/2026 5:25:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 13h 15m

Did you know that if you travel from Mobile, AL to Tupelo, MS via Birmingham, AL, you can save more than $19? You can find the corresponding connections below.
- Greyhound US
  
  13h 15m
  
  0
  
  4:10 PM
  
  Mobile, AL
  Greyhound Bus Station
  
  2:00 AM
  
  Birmingham, AL
  MAX Central Station
  
  0
  
  Economy
  
  $41
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 4/24/2026 4:10:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 4/25/2026 2:00:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 9h 50m
- Greyhound US
  
  2h 40m
  
  0
  
  2:45 AM
  
  Birmingham, AL
  MAX Central Station
  
  5:25 AM
  
  Tupelo, MS
  Bus Stop
  
  0
  
  Economy
  
  $21
  
  A Bus from Greyhound US goes from MAX Central Station, Birmingham, AL (USA) at 4/25/2026 2:45:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/25/2026 5:25:00 AM. 50 Economy ticket for $21 per person are available. Travel duration is 2h 40m
Travel time is 3h 30m longer, but you will save $19

Best Price Offer: The price for the cheapest bus from Mobile, AL to Tupelo, MS is $64 on 4/25/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Mobile, AL and Tupelo, MS

See here how frequent the connections between Mobile, AL and Tupelo, MS are, during different times and days of the week.

Sunday is the busiest day, with more than 2 daily buses from Mobile, AL to Tupelo, MS. Sunday has instead the fewest connections, with only 2 daily coaches between Mobile, AL and Tupelo, MS.

The busiest time of the day is the Morning, with 4 buses from Mobile, AL to Tupelo, MS, while Morning sees the fewest connections between Mobile, AL and Tupelo, MS, with 4 offers.

Facts about the bus from Mobile, AL to Tupelo, MS

Compare all providers like Greyhound US that travel 2 times every day by bus from Mobile, AL to Tupelo, MS in one click! Book your bus ticket from Mobile, AL to Tupelo, MS starting from $64!

Cheapest Bus	$64
Fastest Bus	9h 45m
Earliest Bus	11:40 AM
Latest Bus	4:10 PM
Daily Bus Routes	2 Ø
Distance	248.8 miles
Bus Companies	Greyhound US

Cheapest bus connections from Mobile, AL to Tupelo, MS

Every day, 2 buses from 1 bus companies leave Mobile, AL for Tupelo, MS: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

Tuesday 04/21

$76

Wednesday 04/22

Thursday 04/23

$67

Friday 04/24

Saturday 04/25

$64

Sunday 04/26

$81

Monday 04/27

$83

Tuesday 04/28

$82

Wednesday 04/29

Thursday 04/30

Friday 05/01

Saturday 05/02

Sunday 05/03

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

Saturday 05/09

Sunday 05/10

$69

Monday 05/11

$72

Tuesday 05/12

Wednesday 05/13

Thursday 05/14

$72

Friday 05/15

Saturday 05/16

The cheapest time to travel from Mobile, AL to Tupelo, MS

See here on which day and which time of the day you can find the cheapest bus ticket from Mobile, AL to Tupelo, MS, for the next 30 days.

With a price starting from $64, Saturday is the cheapest day for a bus from Mobile, AL to Tupelo, MS. Tuesday instead is the most expensive day with prices starting from $76.

Afternoon is the cheapest day time for bus tickets from Mobile, AL to Tupelo, MS, with $64. Morning is the most expensive time of the day with prices starting from $65.

How to save money travelling from Mobile, AL to Tupelo, MS

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mobile, AL to Tupelo, MS in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mobile, AL to Tupelo, MS, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mobile, AL to Tupelo, MS are also emptier.

All bus stations and stops in Mobile, AL and Tupelo, MS

In the map below, you can see where to find all bus stations in Mobile, AL and Tupelo, MS.

I-65 Hwy Exit 4 McDonald's

Springdale Blvd 2

GM&O Transit Center

Beauregard St 110

Greyhound Bus Station

Government Blvd 1545

Bus Stop

S Eason Blvd 2831

Service and Comfort on the bus from Mobile, AL to Tupelo, MS

Want to know which seat classes are available on the buses from Mobile, AL to Tupelo, MS? Or which bus companies serve the route Mobile, AL to Tupelo, MS? Below you will find answers to your questions.

FAQs about the Mobile, AL to Tupelo, MS bus

How much does a Mobile, AL Tupelo, MS bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $64 and takes 13h 15m to reach Tupelo, MS. Compare offers to save money!

How much could I save by comparing buses from Mobile, AL to Tupelo, MS?

This route is offered by 1 companies with a range of ticket prices between $64 and $83. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Tupelo, MS.

On average, how many connections are available from Mobile, AL to Tupelo, MS each day?

Every day, the Mobile, AL to Tupelo, MS bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mobile, AL to Tupelo, MS take?

The fastest bus from Mobile, AL to Tupelo, MS is offered by Greyhound US and takes 9h 45m. Bus tickets for this connection cost $76. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mobile, AL to Tupelo, MS?

The earliest bus arriving in Tupelo, MS from Mobile, AL starts at 11:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mobile, AL to Tupelo, MS?

The latest bus trip departing from Mobile, AL for Tupelo, MS starts at 4:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mobile, AL Tupelo, MS route?

When traveling by bus from Mobile, AL to Tupelo, MS, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mobile, AL and Tupelo, MS?

You can check all the direct connections between Mobile, AL and Tupelo, MS by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mobile, AL to Tupelo, MS bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mobile, AL Tupelo, MS bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mobile, AL Tupelo, MS bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mobile, AL to Tupelo, MS on your planned travel date.

How does CheckMyBus find the best bus deals from Mobile, AL to Tupelo, MS?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Mobile, AL and Tupelo, MS. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mobile, AL to Tupelo, MS?

Prices and availability for 2 trips between Mobile, AL and Tupelo, MS change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mobile, AL to Tupelo, MS

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mobile, AL and to Tupelo, MS

Here’s an overview of the most popular bus routes to Mobile, AL and to Tupelo, MS. Simply click on the connection of your choice, and you will find all the details about your bus route!