Which bus from Columbia, MO to Tupelo, MS is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $83
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Compare all timetables for the bus from Columbia, MO to Tupelo, MS

Here is a selection of the cheapest bus trips from the schedule from Columbia, MO to Tupelo, MS from various bus operators like Greyhound US for the next days.

today
$111
tomorrow
Sunday
Monday
$100
Tuesday
Wednesday
Thursday
$116

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 14h 35m 8:05 PM Columbia, MO Bus Stop 10:40 AM Tupelo, MS Bus Stop  Economy $111
Greyhound US 14h 5m 8:35 PM Columbia, MO Red Thread 10:40 AM Tupelo, MS Bus Stop  Economy $112
Greyhound US 14h 35m 8:30 AM Columbia, MO Bus Stop 11:05 PM Tupelo, MS Bus Stop  Economy $113
Greyhound US 12h 25m 10:40 AM Columbia, MO Red Thread 11:05 PM Tupelo, MS Bus Stop  Economy $115

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 14h 5m 8:35 PM Columbia, MO Red Thread 10:40 AM Tupelo, MS Bus Stop  Economy $100
Greyhound US 14h 35m 8:05 PM Columbia, MO Bus Stop 10:40 AM Tupelo, MS Bus Stop  Economy $101
Greyhound US 12h 25m 10:40 AM Columbia, MO Red Thread 11:05 PM Tupelo, MS Bus Stop  Economy $101
Greyhound US 14h 35m 8:30 AM Columbia, MO Bus Stop 11:05 PM Tupelo, MS Bus Stop  Economy $102

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 14h 35m 8:30 AM Columbia, MO Bus Stop 11:05 PM Tupelo, MS Bus Stop  Economy $116
Greyhound US 14h 5m 8:35 PM Columbia, MO Red Thread 10:40 AM Tupelo, MS Bus Stop  Economy $116
Greyhound US 14h 35m 8:05 PM Columbia, MO Bus Stop 10:40 AM Tupelo, MS Bus Stop  Economy $118
Greyhound US 12h 25m 10:40 AM Columbia, MO Red Thread 11:05 PM Tupelo, MS Bus Stop  Economy $118
  • Did you know that if you travel from Columbia, MO to Tupelo, MS via St. Louis, MO, you can save more than $20? You can find the corresponding connections below.
    • FlixBus
      12h 25m
      0
      10:40 AM
      Columbia, MO
      Red Thread
      12:55 PM
      St. Louis, MO
      Gateway Station
      0
      FlixBus
      Economy
      $27
      • Waiting Time 3h 5m
    • FlixBus
      7h 5m
      0
      4:00 PM
      St. Louis, MO
      Gateway Station
      11:05 PM
      Tupelo, MS
      Bus Stop
      0
      FlixBus
      Economy
      $69
    Travel time is the same as the direct connection, but you will save $20

Best Price Offer: The price for the cheapest bus from Columbia, MO to Tupelo, MS is $83 on 12/2/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Columbia, MO and Tupelo, MS

See here how frequent the connections between Columbia, MO and Tupelo, MS are, during different times and days of the week.
Monday is the busiest day, with more than 4 daily buses from Columbia, MO to Tupelo, MS. Monday has instead the fewest connections, with only 4 daily coaches between Columbia, MO and Tupelo, MS.
The busiest time of the day is the Morning, with 6 buses from Columbia, MO to Tupelo, MS, while Morning sees the fewest connections between Columbia, MO and Tupelo, MS, with 6 offers.

Facts about the bus from Columbia, MO to Tupelo, MS

Compare all providers like Greyhound US that travel 4 times every day by bus from Columbia, MO to Tupelo, MS in one click! Book your bus ticket from Columbia, MO to Tupelo, MS starting from $83!

Cheapest Bus $83
Fastest Bus 12h 25m
Earliest Bus 8:30 AM
Latest Bus 8:35 PM
Daily Bus Routes 4 Ø
Distance 381.7 miles
Bus Companies Greyhound US

Cheapest bus connections from Columbia, MO to Tupelo, MS

Every day, 4 buses from 1 bus companies leave Columbia, MO for Tupelo, MS: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/30
Monday 12/01
Tuesday 12/02
Wednesday 12/03
Thursday 12/04
Friday 12/05
$111
Saturday 12/06
Sunday 12/07
Monday 12/08
$100
Tuesday 12/09
Wednesday 12/10
Thursday 12/11
$116
Friday 12/12
Saturday 12/13
$93
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
Friday 12/19
Saturday 12/20
Sunday 12/21
Monday 12/22
Tuesday 12/23
Wednesday 12/24
Thursday 12/25
Friday 12/26
Saturday 12/27

The cheapest time to travel from Columbia, MO to Tupelo, MS

See here on which day and which time of the day you can find the cheapest bus ticket from Columbia, MO to Tupelo, MS, for the next 30 days.
With a price starting from $100, Monday is the cheapest day for a bus from Columbia, MO to Tupelo, MS. Thursday instead is the most expensive day with prices starting from $116.
Evening is the cheapest day time for bus tickets from Columbia, MO to Tupelo, MS, with $100. Morning is the most expensive time of the day with prices starting from $101.

How to save money travelling from Columbia, MO to Tupelo, MS

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Columbia, MO to Tupelo, MS in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Columbia, MO to Tupelo, MS, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Columbia, MO to Tupelo, MS are also emptier.

Beloved bus companies from Columbia, MO to Tupelo, MS

These are the most booked bus companies between Columbia, MO to Tupelo, MS from our users.

Greyhound US from Columbia, MO to Tupelo, MS

Greyhound US

Here you will find the key facts about the Greyhound US bus route Columbia, MO to Tupelo, MS:

Cheapest Price $100
Fastest Bus 12h 25m
Earliest Bus 8:30 AM
Last Bus 8:35 PM
Daily Connections 4 Ø
Found on 12/3/2025

All bus stations and stops in Columbia, MO and Tupelo, MS

In the map below, you can see where to find all bus stations in Columbia, MO and Tupelo, MS.

Service and Comfort on the bus from Columbia, MO to Tupelo, MS

Want to know which seat classes are available on the buses from Columbia, MO to Tupelo, MS? Or which bus companies serve the route Columbia, MO to Tupelo, MS? Below you will find answers to your questions.

FAQs about the Columbia, MO to Tupelo, MS bus

How much does a Columbia, MO Tupelo, MS bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $83 and takes 14h 5m to reach Tupelo, MS. Compare offers to save money!

How much could I save by comparing buses from Columbia, MO to Tupelo, MS?

This route is offered by 1 companies with a range of ticket prices between $83 and $118. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Tupelo, MS.

On average, how many connections are available from Columbia, MO to Tupelo, MS each day?

Every day, the Columbia, MO to Tupelo, MS bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Columbia, MO to Tupelo, MS take?

The fastest bus from Columbia, MO to Tupelo, MS is offered by Greyhound US and takes 12h 25m. Bus tickets for this connection cost $115. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Columbia, MO to Tupelo, MS?

The earliest bus arriving in Tupelo, MS from Columbia, MO starts at 8:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Columbia, MO to Tupelo, MS?

The latest bus trip departing from Columbia, MO for Tupelo, MS starts at 8:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Columbia, MO Tupelo, MS route?

When traveling by bus from Columbia, MO to Tupelo, MS, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Columbia, MO and Tupelo, MS?

You can check all the direct connections between Columbia, MO and Tupelo, MS by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Columbia, MO to Tupelo, MS bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Columbia, MO Tupelo, MS bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Columbia, MO Tupelo, MS bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Columbia, MO to Tupelo, MS on your planned travel date.

Available seat classes which are offered on the bus route Columbia, MO to Tupelo, MS

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Columbia, MO and to Tupelo, MS

Here’s an overview of the most popular bus routes to Columbia, MO and to Tupelo, MS. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Kansas City - Columbia, MO Bus Kansas City - Columbia, MO
Buses to Columbia, MO from St. Louis, MO Buses to Columbia, MO from St. Louis, MO
Buses to Columbia, MO from Chicago Buses to Columbia, MO from Chicago
Buses from New York to Columbia, MO Buses from New York to Columbia, MO
Buses Meridian, MS - Tupelo, MS Buses Meridian, MS - Tupelo, MS
Buses Baton Rouge - Tupelo, MS Buses Baton Rouge - Tupelo, MS
Buses to Tupelo, MS from Memphis Buses to Tupelo, MS from Memphis
Buses Atlanta, GA to Tupelo, MS Buses Atlanta, GA to Tupelo, MS
Popular Airport Shuttles to Columbia, MO and to Tupelo, MS
CheckMyBus › Buses in USA › Bus to Columbia, MO › Bus to Tupelo, MS

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