Bus Perugia to Palermo: Compare prices and save money

Compare all timetables for the bus from Perugia to Palermo

Here is a selection of the cheapest bus trips from the schedule from Perugia to Palermo from various bus operators like FlixBus for the next days.

today

$66

tomorrow

$65

Monday

$57

Tuesday

$54

Wednesday

$57

Thursday

$49

Friday

$63

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	18h 30m	8:45 PM	Perugia	Piazza Partigiani Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$66	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/11/2026 8:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/12/2026 3:15:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 18h 30m
	FlixBus	19h 0m	4:00 PM	Perugia	Piazza Partigiani Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$86	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/11/2026 4:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/12/2026 11:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 19h 0m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	18h 30m	8:45 PM	Perugia	Piazza Partigiani Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$65	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/12/2026 8:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/13/2026 3:15:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 18h 30m
	FlixBus	19h 0m	4:00 PM	Perugia	Piazza Partigiani Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$113	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/12/2026 4:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/13/2026 11:00:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 19h 0m

Did you know that if you travel from Perugia to Palermo via Rome, you can save more than $8? You can find the corresponding connections below.
- Autolinee Federico
  
  20h 0m
  
  0
  
  7:15 PM
  
  Perugia
  Piazza Partigiani Bus Station
  
  10:30 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Basic
  
  $8
  
  A Bus from Autolinee Federico goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/13/2026 7:15:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 4/13/2026 10:30:00 PM. 50 Basic ticket for $8 per person are available. Travel duration is 3h 15m
- FlixBus
  
  13h 55m
  
  0
  
  1:20 AM
  
  Rome
  Tiburtina Bus Station
  
  3:15 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  0
  
  Economy
  
  $49
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 4/14/2026 1:20:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/14/2026 3:15:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 13h 55m
Travel time is 1h 30m longer, but you will save $8

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	18h 30m	8:45 PM	Perugia	Piazza Partigiani Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$57	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/13/2026 8:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/14/2026 3:15:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 18h 30m
	FlixBus	19h 0m	4:00 PM	Perugia	Piazza Partigiani Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$75	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/13/2026 4:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/14/2026 11:00:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 19h 0m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	18h 30m	8:45 PM	Perugia	Piazza Partigiani Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$54	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/14/2026 8:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/15/2026 3:15:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 18h 30m
	FlixBus	19h 0m	4:00 PM	Perugia	Piazza Partigiani Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$62	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/14/2026 4:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/15/2026 11:00:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 19h 0m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	22h 35m	8:45 PM	Perugia	Piazza Partigiani Bus Station	7:20 PM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$57	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/15/2026 8:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/16/2026 7:20:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 22h 35m
	FlixBus	20h 30m	2:30 PM	Perugia	Piazza Partigiani Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$77	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/15/2026 2:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/16/2026 11:00:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 20h 30m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	22h 35m	8:45 PM	Perugia	Piazza Partigiani Bus Station	7:20 PM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$49	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/16/2026 8:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/17/2026 7:20:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 22h 35m
	FlixBus	19h 0m	4:00 PM	Perugia	Piazza Partigiani Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$73	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/16/2026 4:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/17/2026 11:00:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 19h 0m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	18h 30m	8:45 PM	Perugia	Piazza Partigiani Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$63	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/17/2026 8:45:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/18/2026 3:15:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 18h 30m
	FlixBus	19h 0m	4:00 PM	Perugia	Piazza Partigiani Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop		Economy	$94	A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/17/2026 4:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/18/2026 11:00:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 19h 0m

Did you know that if you travel from Perugia to Palermo via Rome, you can save more than $14? You can find the corresponding connections below.
- FlixBus
  
  23h 15m
  
  0
  
  4:00 PM
  
  Perugia
  Piazza Partigiani Bus Station
  
  6:20 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $7
  
  A Bus from FlixBus goes from Piazza Partigiani Bus Station, Perugia (Italy) at 4/18/2026 4:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 4/18/2026 6:20:00 PM. 50 Economy ticket for $7 per person are available. Travel duration is 2h 20m
- FlixBus
  
  15h 45m
  
  0
  
  11:30 PM
  
  Rome
  Tiburtina Bus Station
  
  3:15 PM
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  0
  
  Economy
  
  $42
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 4/18/2026 11:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 4/19/2026 3:15:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 15h 45m
Travel time is 4h 45m longer, but you will save $14

Best Price Offer: The price for the cheapest bus from Perugia to Palermo is $49 on 4/16/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Perugia and Palermo

See here how frequent the connections between Perugia and Palermo are, during different times and days of the week.

Sunday is the busiest day, with more than 2 daily buses from Perugia to Palermo. Sunday has instead the fewest connections, with only 2 daily coaches between Perugia and Palermo.

The busiest time of the day is the Afternoon, with 7 buses from Perugia to Palermo, while Afternoon sees the fewest connections between Perugia and Palermo, with 7 offers.

Facts about the bus from Perugia to Palermo

Compare all providers like FlixBus that travel 2 times every day by bus from Perugia to Palermo in one click! Book your bus ticket from Perugia to Palermo starting from $49!

Cheapest Bus	$49
Fastest Bus	18h 30m
Earliest Bus	4:00 PM
Latest Bus	8:45 PM
Daily Bus Routes	2 Ø
Distance	349.0 miles
Bus Companies	FlixBus

Cheapest bus connections from Perugia to Palermo

Every day, 2 buses from 1 bus companies leave Perugia for Palermo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/11/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/05

Monday 04/06

Tuesday 04/07

Wednesday 04/08

Thursday 04/09

Friday 04/10

Saturday 04/11

$66

Sunday 04/12

$65

Monday 04/13

$57

Tuesday 04/14

$54

Wednesday 04/15

$57

Thursday 04/16

$49

Friday 04/17

$63

Saturday 04/18

$57

Sunday 04/19

$59

Monday 04/20

$55

Tuesday 04/21

$51

Wednesday 04/22

$69

Thursday 04/23

$95

Friday 04/24

$83

Saturday 04/25

$65

Sunday 04/26

$76

Monday 04/27

$63

Tuesday 04/28

$65

Wednesday 04/29

$83

Thursday 04/30

$83

Friday 05/01

$59

Saturday 05/02

The cheapest time to travel from Perugia to Palermo

See here on which day and which time of the day you can find the cheapest bus ticket from Perugia to Palermo, for the next 30 days.

With a price starting from $46, Thursday is the cheapest day for a bus from Perugia to Palermo. Friday instead is the most expensive day with prices starting from $59.

Evening is the cheapest day time for bus tickets from Perugia to Palermo, with $49. Afternoon is the most expensive time of the day with prices starting from $62.

How to save money travelling from Perugia to Palermo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Perugia to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Perugia to Palermo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Perugia to Palermo are also emptier.

All bus stations and stops in Perugia and Palermo

In the map below, you can see where to find all bus stations in Perugia and Palermo.

Piazza Partigiani Bus Station

Perugia-Autostazione Piazza Partigiani Perugia-Autostazione Piazza Partigiani

Bus Stop

Capolinea Bus Fontivegge (fronte stazione mini-metrò)

Piazza Italia

Piazza Italia 5-10

Universita' Train Station

Oreto Orsi Bus Stop

Via Oreto 389

Piazza Cairoli Bus Station

Piazza Cairoli Piazza Cairoli

Piazza Indipendenza Station

Piazza Indipendenza Palazzo Reale

Via Tommaso Fazello Bus Stop

Via Tommaso Fazello

Via della Libertà

Via della Libertà 163

Service and Comfort on the bus from Perugia to Palermo

Want to know which seat classes are available on the buses from Perugia to Palermo? Or which bus companies serve the route Perugia to Palermo? Below you will find answers to your questions.

FAQs about the Perugia to Palermo bus

How much does a Perugia Palermo bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $49 and takes 22h 35m to reach Palermo. Compare offers to save money!

How much could I save by comparing buses from Perugia to Palermo?

This route is offered by 1 companies with a range of ticket prices between $49 and $113. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Palermo.

On average, how many connections are available from Perugia to Palermo each day?

Every day, the Perugia to Palermo bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Perugia to Palermo take?

The fastest bus from Perugia to Palermo is offered by FlixBus and takes 18h 30m. Bus tickets for this connection cost $66. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Perugia to Palermo?

The earliest bus arriving in Palermo from Perugia starts at 4:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Perugia to Palermo?

The latest bus trip departing from Perugia for Palermo starts at 8:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Perugia Palermo route?

When traveling by bus from Perugia to Palermo, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Perugia and Palermo?

You can check all the direct connections between Perugia and Palermo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Perugia to Palermo bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Perugia Palermo bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Perugia Palermo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Perugia to Palermo on your planned travel date.

How does CheckMyBus find the best bus deals from Perugia to Palermo?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Perugia and Palermo. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Perugia to Palermo?

Prices and availability for 2 trips between Perugia and Palermo change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Perugia to Palermo

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Perugia and to Palermo

Here’s an overview of the most popular bus routes to Perugia and to Palermo. Simply click on the connection of your choice, and you will find all the details about your bus route!