Bus Rome to Palermo: Compare prices and save money

Compare all timetables for the bus from Rome to Palermo

Here is a selection of the cheapest bus trips from the schedule from Rome to Palermo from various bus operators like FlixBus, Itabus or Autoservizi Salemi for the next days.

today

$45

tomorrow

$43

Wednesday

$42

Thursday

$33

Friday

$30

Saturday

$27

Sunday

$27

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Autoservizi Salemi	11h 45m	8:00 PM	Rome	Tiburtina Bus Station	7:45 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$45	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 9/14/2026 8:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/15/2026 7:45:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 11h 45m
FlixBus	15h 45m	11:30 PM	Rome	Tiburtina Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$68	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/14/2026 11:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/15/2026 3:15:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 15h 45m
FlixBus	14h 0m	9:00 PM	Rome	Tiburtina Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$86	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/14/2026 9:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/15/2026 11:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 14h 0m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 55m	1:20 AM	Rome	Tiburtina Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$43	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/15/2026 1:20:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/15/2026 3:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 13h 55m
FlixBus	15h 45m	11:30 PM	Rome	Tiburtina Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$58	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/15/2026 11:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/16/2026 3:15:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 15h 45m
FlixBus	14h 0m	9:00 PM	Rome	Tiburtina Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$96	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/15/2026 9:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/16/2026 11:00:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 14h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 55m	1:20 AM	Rome	Tiburtina Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$42	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/16/2026 1:20:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/16/2026 3:15:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	11h 45m	8:00 PM	Rome	Tiburtina Bus Station	7:45 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$45	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 9/16/2026 8:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/17/2026 7:45:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 11h 45m
FlixBus	15h 45m	11:30 PM	Rome	Tiburtina Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$50	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/16/2026 11:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/17/2026 3:15:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 15h 45m
FlixBus	14h 0m	9:00 PM	Rome	Tiburtina Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$66	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/16/2026 9:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/17/2026 11:00:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 14h 0m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 55m	1:20 AM	Rome	Tiburtina Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$33	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/17/2026 1:20:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/17/2026 3:15:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	11h 45m	8:00 PM	Rome	Tiburtina Bus Station	7:45 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$46	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 9/17/2026 8:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/18/2026 7:45:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 11h 45m
FlixBus	15h 45m	11:30 PM	Rome	Tiburtina Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$61	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/17/2026 11:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/18/2026 3:15:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 15h 45m
FlixBus	14h 0m	9:00 PM	Rome	Tiburtina Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$87	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/17/2026 9:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/18/2026 11:00:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 14h 0m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 55m	1:20 AM	Rome	Tiburtina Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$30	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/18/2026 1:20:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/18/2026 3:15:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 13h 55m
Itabus	13h 35m	6:15 PM	Rome	Tiburtina Bus Station	7:50 AM	Palermo	Piazza Cairoli Bus Station	Economy	$33	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 9/18/2026 6:15:00 PM to Piazza Cairoli Bus Station, Palermo (Italy) arriving at 9/19/2026 7:50:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 13h 35m
Autoservizi Salemi	11h 45m	8:00 PM	Rome	Tiburtina Bus Station	7:45 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$46	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 9/18/2026 8:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/19/2026 7:45:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 11h 45m
FlixBus	15h 45m	11:30 PM	Rome	Tiburtina Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$74	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/18/2026 11:30:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/19/2026 3:15:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 15h 45m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	13h 35m	6:15 PM	Rome	Tiburtina Bus Station	7:50 AM	Palermo	Via Fazello	Premium Economy	$27	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 9/19/2026 6:15:00 PM to Via Fazello, Palermo (Italy) arriving at 9/20/2026 7:50:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 13h 35m
FlixBus	14h 0m	9:00 PM	Rome	Tiburtina Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$36	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/19/2026 9:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/20/2026 11:00:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 14h 0m
FlixBus	13h 55m	1:20 AM	Rome	Tiburtina Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$37	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/19/2026 1:20:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/19/2026 3:15:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	11h 45m	8:00 PM	Rome	Tiburtina Bus Station	7:45 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$45	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 9/19/2026 8:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/20/2026 7:45:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 11h 45m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	13h 35m	6:15 PM	Rome	Tiburtina Bus Station	7:50 AM	Palermo	Via Fazello	Premium Economy	$27	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 9/20/2026 6:15:00 PM to Via Fazello, Palermo (Italy) arriving at 9/21/2026 7:50:00 AM. 50 Premium Economy ticket for $27 per person are available. Travel duration is 13h 35m
FlixBus	13h 55m	1:20 AM	Rome	Tiburtina Bus Station	3:15 PM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$30	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/20/2026 1:20:00 AM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/20/2026 3:15:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 13h 55m
Autoservizi Salemi	11h 45m	8:00 PM	Rome	Tiburtina Bus Station	7:45 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$35	A Bus from Autoservizi Salemi goes from Tiburtina Bus Station, Rome (Italy) at 9/20/2026 8:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/21/2026 7:45:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 11h 45m
FlixBus	14h 0m	9:00 PM	Rome	Tiburtina Bus Station	11:00 AM	Palermo	Via Tommaso Fazello Bus Stop	Economy	$65	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 9/20/2026 9:00:00 PM to Via Tommaso Fazello Bus Stop, Palermo (Italy) arriving at 9/21/2026 11:00:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 14h 0m

Best Price Offer: The price for the cheapest bus from Rome to Palermo is $20 on 9/23/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Rome and Palermo

See here how frequent the connections between Rome and Palermo are, during different times and days of the week.

Sunday is the busiest day, with more than 10 daily buses from Rome to Palermo. Tuesday has instead the fewest connections, with only 3 daily coaches between Rome and Palermo.

The busiest time of the day is the Evening, with 35 buses from Rome to Palermo, while Afternoon sees the fewest connections between Rome and Palermo, with 2 offers.

Facts about the bus from Rome to Palermo

Compare all providers like FlixBus, Itabus and Autoservizi Salemi that travel 6 times every day by bus from Rome to Palermo in one click! Book your bus ticket from Rome to Palermo starting from $20!

Cheapest Bus	$20
Fastest Bus	11h 45m
Earliest Bus	8:00 PM
Latest Bus	11:30 PM
Daily Bus Routes	6 Ø
Distance	265.6 miles
Bus Companies	FlixBus, Itabus and Autoservizi Salemi

Cheapest bus connections from Rome to Palermo

Every day, 6 buses from 3 bus companies leave Rome for Palermo: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/14/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/13

Monday 09/14

$68

Tuesday 09/15

$43

Wednesday 09/16

$42

Thursday 09/17

$33

Friday 09/18

$30

Saturday 09/19

$36

Sunday 09/20

$30

Monday 09/21

$32

Tuesday 09/22

$26

Wednesday 09/23

$20

Thursday 09/24

$20

Friday 09/25

$31

Saturday 09/26

$30

Sunday 09/27

$35

Monday 09/28

$35

Tuesday 09/29

$20

Wednesday 09/30

$20

Thursday 10/01

$20

Friday 10/02

$30

Saturday 10/03

$20

Sunday 10/04

$20

Monday 10/05

$28

Tuesday 10/06

$28

Wednesday 10/07

$20

Thursday 10/08

$30

Friday 10/09

$33

Saturday 10/10

The cheapest time to travel from Rome to Palermo

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Palermo, for the next 30 days.

With a price starting from $20, Sunday is the cheapest day for a bus from Rome to Palermo. Friday instead is the most expensive day with prices starting from $30.

Night is the cheapest day time for bus tickets from Rome to Palermo, with $20. Afternoon is the most expensive time of the day with prices starting from $40.

How to save money travelling from Rome to Palermo

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Palermo in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Palermo, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Palermo are also emptier.

Beloved bus companies from Rome to Palermo

These are the most booked bus companies between Rome to Palermo from our users.

Autoservizi Salemi from Rome to Palermo

Here you will find the key facts about the Autoservizi Salemi bus route Rome to Palermo:

Cheapest Price	$35
Fastest Bus	11h 45m
Earliest Bus	8:00 PM
Last Bus	8:00 PM
Daily Connections	1 Ø
Found on	9/11/2026

FlixBus from Rome to Palermo

Here you will find the key facts about the FlixBus bus route Rome to Palermo:

Cheapest Price	$30
Fastest Bus	13h 55m
Earliest Bus	9:00 PM
Last Bus	11:30 PM
Daily Connections	3 Ø
Found on	9/14/2026

All bus stations and stops in Rome and Palermo

In the map below, you can see where to find all bus stations in Rome and Palermo.

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Oreto Orsi Bus Stop

Via Oreto 389

Piazza Cairoli Bus Station

Piazza Cairoli Piazza Cairoli

Piazza Indipendenza Station

Piazza Indipendenza Palazzo Reale

Via Tommaso Fazello Bus Stop

Via Tommaso Fazello

Via della Libertà

Via della Libertà 163

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Palermo? Compare all modes of transports from Rome to Palermo.

Service and Comfort on the bus from Rome to Palermo

Want to know which seat classes are available on the buses from Rome to Palermo? Or which bus companies serve the route Rome to Palermo? Below you will find answers to your questions.

FAQs about the Rome to Palermo bus

How much does a Rome Palermo bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $20 and takes 13h 35m to reach Palermo. Compare offers to save money!

How much could I save by comparing buses from Rome to Palermo?

This route is offered by 3 companies with a range of ticket prices between $20 and $96. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Palermo.

On average, how many connections are available from Rome to Palermo each day?

Every day, the Rome to Palermo bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Palermo take?

The fastest bus from Rome to Palermo is offered by Autoservizi Salemi and takes 11h 45m. Bus tickets for this connection cost $45. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Palermo?

The earliest bus arriving in Palermo from Rome starts at 8:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Palermo?

The latest bus trip departing from Rome for Palermo starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Palermo route?

When traveling by bus from Rome to Palermo, passengers can travel with FlixBus, Itabus and Autoservizi Salemi. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Palermo?

You can check all the direct connections between Rome and Palermo by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and Autoservizi Salemi.

What can I take with me on the Rome to Palermo bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Palermo bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Palermo bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Palermo on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Palermo?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Rome and Palermo. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Palermo?

Prices and availability for 6 trips between Rome and Palermo change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Palermo

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Rome and to Palermo

Here’s an overview of the most popular bus routes to Rome and to Palermo. Simply click on the connection of your choice, and you will find all the details about your bus route!