Bus Prague to Dusseldorf: Compare prices and save money

Compare all timetables for the bus from Prague to Dusseldorf

Here is a selection of the cheapest bus trips from the schedule from Prague to Dusseldorf from various bus operators like FlixBus or RegioJet for the next days.

today

$46

tomorrow

$46

Monday

$41

Tuesday

$41

Wednesday

$40

Thursday

$41

Friday

$46

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
RegioJet	10h 0m	11:00 PM	Prague	ÚAN Florenc	9:00 AM	Dusseldorf	Central Bus Station	Economy	$46	A Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 6/20/2026 11:00:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/21/2026 9:00:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 0m
FlixBus	10h 45m	5:45 PM	Prague	Na Knížecí Station	4:30 AM	Dusseldorf	Central Bus Station	Economy	$54	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 6/20/2026 5:45:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/21/2026 4:30:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 10h 45m
FlixBus	13h 25m	3:05 PM	Prague	Zličín	4:30 AM	Dusseldorf	Central Bus Station	Economy	$54	A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 6/20/2026 3:05:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/21/2026 4:30:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 13h 25m
FlixBus	11h 45m	6:30 PM	Prague	Wilsonova Bus Station	6:15 AM	Dusseldorf	Central Bus Station	Economy	$55	A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 6/20/2026 6:30:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/21/2026 6:15:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 11h 45m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
RegioJet	10h 0m	11:00 PM	Prague	ÚAN Florenc	9:00 AM	Dusseldorf	Central Bus Station	Economy	$46	A Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 6/21/2026 11:00:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/22/2026 9:00:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 0m
FlixBus	17h 40m	11:05 PM	Prague	ÚAN Florenc	4:45 PM	Dusseldorf	Düsseldorf Bus Stop	Economy	$59	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/21/2026 11:05:00 PM to Düsseldorf Bus Stop, Dusseldorf (Germany) arriving at 6/22/2026 4:45:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 17h 40m
FlixBus	15h 30m	2:55 AM	Prague	Wilsonova Bus Station	6:25 PM	Dusseldorf	Düsseldorf Bus Stop	Economy	$62	A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 6/21/2026 2:55:00 AM to Düsseldorf Bus Stop, Dusseldorf (Germany) arriving at 6/21/2026 6:25:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 15h 30m
FlixBus	10h 45m	8:00 PM	Prague	ÚAN Florenc	6:45 AM	Dusseldorf	Central Bus Station	Economy	$69	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/21/2026 8:00:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/22/2026 6:45:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 10h 45m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	11h 45m	10:55 AM	Prague	Na Knížecí Station	10:40 PM	Dusseldorf	Central Bus Station	Economy	$41	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 6/22/2026 10:55:00 AM to Central Bus Station, Dusseldorf (Germany) arriving at 6/22/2026 10:40:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 11h 45m
FlixBus	12h 10m	10:30 AM	Prague	ÚAN Florenc	10:40 PM	Dusseldorf	Central Bus Station	Economy	$41	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/22/2026 10:30:00 AM to Central Bus Station, Dusseldorf (Germany) arriving at 6/22/2026 10:40:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 12h 10m
FlixBus	12h 45m	9:10 AM	Prague	Na Knížecí Station	9:55 PM	Dusseldorf	Central Bus Station	Economy	$42	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 6/22/2026 9:10:00 AM to Central Bus Station, Dusseldorf (Germany) arriving at 6/22/2026 9:55:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 12h 45m
RegioJet	10h 0m	11:00 PM	Prague	ÚAN Florenc	9:00 AM	Dusseldorf	Central Bus Station	Economy	$46	A Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 6/22/2026 11:00:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/23/2026 9:00:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 0m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 45m	9:10 AM	Prague	Na Knížecí Station	9:55 PM	Dusseldorf	Central Bus Station	Economy	$41	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 6/23/2026 9:10:00 AM to Central Bus Station, Dusseldorf (Germany) arriving at 6/23/2026 9:55:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 12h 45m
FlixBus	13h 5m	8:50 AM	Prague	ÚAN Florenc	9:55 PM	Dusseldorf	Central Bus Station	Economy	$41	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/23/2026 8:50:00 AM to Central Bus Station, Dusseldorf (Germany) arriving at 6/23/2026 9:55:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 13h 5m
FlixBus	10h 45m	8:00 PM	Prague	ÚAN Florenc	6:45 AM	Dusseldorf	Central Bus Station	Economy	$42	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/23/2026 8:00:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/24/2026 6:45:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 10h 45m
RegioJet	10h 0m	11:00 PM	Prague	ÚAN Florenc	9:00 AM	Dusseldorf	Central Bus Station	Economy	$46	A Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 6/23/2026 11:00:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/24/2026 9:00:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 45m	9:10 AM	Prague	Na Knížecí Station	9:55 PM	Dusseldorf	Central Bus Station	Economy	$40	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 6/24/2026 9:10:00 AM to Central Bus Station, Dusseldorf (Germany) arriving at 6/24/2026 9:55:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 12h 45m
FlixBus	13h 5m	8:50 AM	Prague	ÚAN Florenc	9:55 PM	Dusseldorf	Central Bus Station	Economy	$40	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/24/2026 8:50:00 AM to Central Bus Station, Dusseldorf (Germany) arriving at 6/24/2026 9:55:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 13h 5m
FlixBus	11h 45m	10:55 AM	Prague	Na Knížecí Station	10:40 PM	Dusseldorf	Central Bus Station	Economy	$41	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 6/24/2026 10:55:00 AM to Central Bus Station, Dusseldorf (Germany) arriving at 6/24/2026 10:40:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 11h 45m
RegioJet	10h 0m	11:00 PM	Prague	ÚAN Florenc	9:00 AM	Dusseldorf	Central Bus Station	Economy	$46	A Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 6/24/2026 11:00:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/25/2026 9:00:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 0m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 45m	9:10 AM	Prague	Na Knížecí Station	9:55 PM	Dusseldorf	Central Bus Station	Economy	$41	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 6/25/2026 9:10:00 AM to Central Bus Station, Dusseldorf (Germany) arriving at 6/25/2026 9:55:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 12h 45m
FlixBus	13h 5m	8:50 AM	Prague	ÚAN Florenc	9:55 PM	Dusseldorf	Central Bus Station	Economy	$41	A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 6/25/2026 8:50:00 AM to Central Bus Station, Dusseldorf (Germany) arriving at 6/25/2026 9:55:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 13h 5m
FlixBus	15h 30m	2:55 AM	Prague	Wilsonova Bus Station	6:25 PM	Dusseldorf	Düsseldorf Bus Stop	Economy	$44	A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 6/25/2026 2:55:00 AM to Düsseldorf Bus Stop, Dusseldorf (Germany) arriving at 6/25/2026 6:25:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 15h 30m
RegioJet	10h 0m	11:00 PM	Prague	ÚAN Florenc	9:00 AM	Dusseldorf	Central Bus Station	Economy	$65	A Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 6/25/2026 11:00:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/26/2026 9:00:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 10h 0m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
RegioJet	10h 0m	11:00 PM	Prague	ÚAN Florenc	9:00 AM	Dusseldorf	Central Bus Station	Economy	$46	A Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 6/26/2026 11:00:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/27/2026 9:00:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 0m
FlixBus	12h 50m	6:30 PM	Prague	Wilsonova Bus Station	7:20 AM	Dusseldorf	Central Bus Station	Economy	$51	A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 6/26/2026 6:30:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/27/2026 7:20:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 12h 50m
FlixBus	13h 5m	11:50 PM	Prague	Wilsonova Bus Station	12:55 PM	Dusseldorf	Central Bus Station	Economy	$51	A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 6/26/2026 11:50:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/27/2026 12:55:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 13h 5m
FlixBus	11h 15m	5:15 PM	Prague	Na Knížecí Station	4:30 AM	Dusseldorf	Central Bus Station	Economy	$51	A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 6/26/2026 5:15:00 PM to Central Bus Station, Dusseldorf (Germany) arriving at 6/27/2026 4:30:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 11h 15m

Best Price Offer: The price for the cheapest bus from Prague to Dusseldorf is $40 on 6/24/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Prague and Dusseldorf

See here how frequent the connections between Prague and Dusseldorf are, during different times and days of the week.

Thursday is the busiest day, with more than 39 daily buses from Prague to Dusseldorf. Monday has instead the fewest connections, with only 35 daily coaches between Prague and Dusseldorf.

The busiest time of the day is the Evening, with 106 buses from Prague to Dusseldorf, while Night sees the fewest connections between Prague and Dusseldorf, with 46 offers.

Facts about the bus from Prague to Dusseldorf

Compare all providers like FlixBus and RegioJet that travel 36 times every day by bus from Prague to Dusseldorf in one click! Book your bus ticket from Prague to Dusseldorf starting from $40!

Cheapest Bus	$40
Fastest Bus	10h 0m
Earliest Bus	1:45 AM
Latest Bus	11:50 PM
Daily Bus Routes	36 Ø
Distance	345.0 miles
Bus Companies	FlixBus and RegioJet

Cheapest bus connections from Prague to Dusseldorf

Every day, 36 buses from 2 bus companies leave Prague for Dusseldorf: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/14

Monday 06/15

Tuesday 06/16

Wednesday 06/17

Thursday 06/18

Friday 06/19

Saturday 06/20

$54

Sunday 06/21

$59

Monday 06/22

$41

Tuesday 06/23

$41

Wednesday 06/24

$40

Thursday 06/25

$41

Friday 06/26

$51

Saturday 06/27

$45

Sunday 06/28

$55

Monday 06/29

$42

Tuesday 06/30

$46

Wednesday 07/01

$42

Thursday 07/02

$45

Friday 07/03

$51

Saturday 07/04

$50

Sunday 07/05

$52

Monday 07/06

$48

Tuesday 07/07

$48

Wednesday 07/08

$43

Thursday 07/09

$44

Friday 07/10

$52

Saturday 07/11

The cheapest time to travel from Prague to Dusseldorf

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Dusseldorf, for the next 30 days.

With a price starting from $39, Tuesday is the cheapest day for a bus from Prague to Dusseldorf. Sunday instead is the most expensive day with prices starting from $46.

Night is the cheapest day time for bus tickets from Prague to Dusseldorf, with $39. Afternoon is the most expensive time of the day with prices starting from $42.

How to save money travelling from Prague to Dusseldorf

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Dusseldorf in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Dusseldorf, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Dusseldorf are also emptier.

Beloved bus companies from Prague to Dusseldorf

These are the most booked bus companies between Prague to Dusseldorf from our users.

FlixBus from Prague to Dusseldorf

Here you will find the key facts about the FlixBus bus route Prague to Dusseldorf:

Cheapest Price	$40
Fastest Bus	10h 40m
Earliest Bus	1:45 AM
Last Bus	11:50 PM
Daily Connections	35 Ø
Found on	6/19/2026

RegioJet from Prague to Dusseldorf

Here you will find the key facts about the RegioJet bus route Prague to Dusseldorf:

Cheapest Price	$46
Fastest Bus	10h 0m
Earliest Bus	11:00 PM
Last Bus	11:00 PM
Daily Connections	1 Ø
Found on	5/26/2026

All bus stations and stops in Prague and Dusseldorf

In the map below, you can see where to find all bus stations in Prague and Dusseldorf.

Na Knížecí Station

Za Ženskými domovy / Ostrovského

ÚAN Florenc

Křižíkova 279

Wilsonova Bus Station

Wilsonova 300/8

Roztyly

Tomíčkova 2234

Černý Most

Bryksova

Central Bus Station

Worringer Str. 140

Berliner Allee Bus Station

Helmholtzstraße Bus Station

Düsseldorf Bus Stop

Düsseldorf Düsseldorf

Eller Bus Stop

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Dusseldorf? Compare all modes of transports from Prague to Dusseldorf.

Service and Comfort on the bus from Prague to Dusseldorf

Want to know which seat classes are available on the buses from Prague to Dusseldorf? Or which bus companies serve the route Prague to Dusseldorf? Below you will find answers to your questions.

FAQs about the Prague to Dusseldorf bus

How much does a Prague Dusseldorf bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $40 and takes 12h 45m to reach Dusseldorf. Compare offers to save money!

How much could I save by comparing buses from Prague to Dusseldorf?

This route is offered by 2 companies with a range of ticket prices between $40 and $151. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Dusseldorf.

On average, how many connections are available from Prague to Dusseldorf each day?

Every day, the Prague to Dusseldorf bus route is served by approximately 36 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Prague to Dusseldorf take?

The fastest bus from Prague to Dusseldorf is offered by RegioJet and takes 10h 0m. Bus tickets for this connection cost $46. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Prague to Dusseldorf?

The earliest bus arriving in Dusseldorf from Prague starts at 1:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Prague to Dusseldorf?

The latest bus trip departing from Prague for Dusseldorf starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Prague Dusseldorf route?

When traveling by bus from Prague to Dusseldorf, passengers can travel with FlixBus and RegioJet. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Prague and Dusseldorf?

You can check all the direct connections between Prague and Dusseldorf by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and RegioJet.

What can I take with me on the Prague to Dusseldorf bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Prague Dusseldorf bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Dusseldorf bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Dusseldorf on your planned travel date.

How does CheckMyBus find the best bus deals from Prague to Dusseldorf?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 36 daily trips between Prague and Dusseldorf. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Prague to Dusseldorf?

Prices and availability for 36 trips between Prague and Dusseldorf change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Prague to Dusseldorf

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Dusseldorf

Here’s an overview of the most popular bus routes to Prague and to Dusseldorf. Simply click on the connection of your choice, and you will find all the details about your bus route!