Bus from Santiago del Estero to Mendoza from $75

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Compare all timetables for the bus from Santiago del Estero to Mendoza

Here is a selection of the cheapest bus trips from the schedule from Santiago del Estero to Mendoza from various bus operators like Andesmar or Autotransportes San Juan for the next days.

today
tomorrow
Friday
$75
Saturday
$75
Sunday
$75
Monday
$75
Tuesday
$75

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Autotransportes San Juan 17h 20m 12:20 AM Santiago del Estero Central Bus Station 5:40 PM Mendoza Bus Station  Premium Economy $75
Andesmar 16h 23m 4:15 PM Santiago del Estero Central Bus Station 8:38 AM Mendoza Bus Station  Premium Economy $76
  • Did you know that if you travel from Santiago del Estero to Mendoza via San Miguel de Tucumán, you can save more than $18? You can find the corresponding connections below.
    • Flecha Bus
      22h 55m
      0
      10:05 AM
      Santiago del Estero
      Central Bus Station
      12:25 PM
      San Miguel de Tucumán
      Bus Station
      0
      Flecha Bus
      Premium Economy
      $12
      • Waiting Time 5h 5m
    • 20 de Junio
      15h 30m
      0
      5:30 PM
      San Miguel de Tucumán
      Bus Station
      9:00 AM
      Mendoza
      Bus Station
      0
      20 de Junio
      Premium Economy
      $45
    Travel time is 6h 32m longer, but you will save $18

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Autotransportes San Juan 17h 20m 12:20 AM Santiago del Estero Central Bus Station 5:40 PM Mendoza Bus Station  Premium Economy $75
Andesmar 16h 23m 4:15 PM Santiago del Estero Central Bus Station 8:38 AM Mendoza Bus Station  Premium Economy $76
  • Did you know that if you travel from Santiago del Estero to Mendoza via San Miguel de Tucumán, you can save more than $18? You can find the corresponding connections below.
    • Flecha Bus
      22h 55m
      0
      10:05 AM
      Santiago del Estero
      Central Bus Station
      12:25 PM
      San Miguel de Tucumán
      Bus Station
      0
      Flecha Bus
      Premium Economy
      $12
      • Waiting Time 5h 5m
    • 20 de Junio
      15h 30m
      0
      5:30 PM
      San Miguel de Tucumán
      Bus Station
      9:00 AM
      Mendoza
      Bus Station
      0
      20 de Junio
      Premium Economy
      $45
    Travel time is 6h 32m longer, but you will save $18

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Autotransportes San Juan 17h 20m 12:20 AM Santiago del Estero Central Bus Station 5:40 PM Mendoza Bus Station  Premium Economy $75
Andesmar 16h 23m 4:15 PM Santiago del Estero Central Bus Station 8:38 AM Mendoza Bus Station  Premium Economy $76
  • Did you know that if you travel from Santiago del Estero to Mendoza via San Miguel de Tucumán, you can save more than $18? You can find the corresponding connections below.
    • Flecha Bus
      21h 50m
      0
      11:10 AM
      Santiago del Estero
      Central Bus Station
      1:30 PM
      San Miguel de Tucumán
      Bus Station
      0
      Flecha Bus
      Premium Economy
      $12
      • Waiting Time 4h 0m
    • 20 de Junio
      15h 30m
      0
      5:30 PM
      San Miguel de Tucumán
      Bus Station
      9:00 AM
      Mendoza
      Bus Station
      0
      20 de Junio
      Premium Economy
      $45
    Travel time is 5h 27m longer, but you will save $18

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Autotransportes San Juan 17h 20m 12:20 AM Santiago del Estero Central Bus Station 5:40 PM Mendoza Bus Station  Premium Economy $75
Andesmar 16h 23m 4:15 PM Santiago del Estero Central Bus Station 8:38 AM Mendoza Bus Station  Premium Economy $76
  • Did you know that if you travel from Santiago del Estero to Mendoza via San Miguel de Tucumán, you can save more than $18? You can find the corresponding connections below.
    • Flecha Bus
      21h 50m
      0
      11:10 AM
      Santiago del Estero
      Central Bus Station
      1:30 PM
      San Miguel de Tucumán
      Bus Station
      0
      Flecha Bus
      Premium Economy
      $12
      • Waiting Time 4h 0m
    • 20 de Junio
      15h 30m
      0
      5:30 PM
      San Miguel de Tucumán
      Bus Station
      9:00 AM
      Mendoza
      Bus Station
      0
      20 de Junio
      Premium Economy
      $45
    Travel time is 5h 27m longer, but you will save $18

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Autotransportes San Juan 17h 20m 12:20 AM Santiago del Estero Central Bus Station 5:40 PM Mendoza Bus Station  Premium Economy $75
Andesmar 16h 23m 4:15 PM Santiago del Estero Central Bus Station 8:38 AM Mendoza Bus Station  Basic $76
  • Did you know that if you travel from Santiago del Estero to Mendoza via San Miguel de Tucumán, you can save more than $18? You can find the corresponding connections below.
    • Flecha Bus
      21h 50m
      0
      11:10 AM
      Santiago del Estero
      Central Bus Station
      1:30 PM
      San Miguel de Tucumán
      Bus Station
      0
      Flecha Bus
      Premium Economy
      $12
      • Waiting Time 4h 0m
    • 20 de Junio
      15h 30m
      0
      5:30 PM
      San Miguel de Tucumán
      Bus Station
      9:00 AM
      Mendoza
      Bus Station
      0
      20 de Junio
      Premium Economy
      $45
    Travel time is 5h 27m longer, but you will save $18

Best Price Offer: The price for the cheapest bus from Santiago del Estero to Mendoza is $75 on 5/4/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Santiago del Estero and Mendoza

See here how frequent the connections between Santiago del Estero and Mendoza are, during different times and days of the week.
Sunday is the busiest day, with more than 13 daily buses from Santiago del Estero to Mendoza. Saturday has instead the fewest connections, with only 9 daily coaches between Santiago del Estero and Mendoza.
The busiest time of the day is the Afternoon, with 33 buses from Santiago del Estero to Mendoza, while Night sees the fewest connections between Santiago del Estero and Mendoza, with 28 offers.

Facts about the bus from Santiago del Estero to Mendoza

Compare all providers like Andesmar and Autotransportes San Juan that travel 12 times every day by bus from Santiago del Estero to Mendoza in one click! Book your bus ticket from Santiago del Estero to Mendoza starting from $75!

Cheapest Bus $75
Fastest Bus 16h 23m
Earliest Bus 12:20 AM
Latest Bus 4:15 PM
Daily Bus Routes 12 Ø
Distance 445.5 miles
Bus Companies Andesmar and Autotransportes San Juan

Cheapest bus connections from Santiago del Estero to Mendoza

Every day, 12 buses from 2 bus companies leave Santiago del Estero for Mendoza: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/06/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/03
Monday 05/04
Tuesday 05/05
Wednesday 05/06
Thursday 05/07
Friday 05/08
$75
Saturday 05/09
$75
Sunday 05/10
$75
Monday 05/11
$75
Tuesday 05/12
$75
Wednesday 05/13
$75
Thursday 05/14
$75
Friday 05/15
$75
Saturday 05/16
$75
Sunday 05/17
$75
Monday 05/18
$75
Tuesday 05/19
$75
Wednesday 05/20
$75
Thursday 05/21
$75
Friday 05/22
$75
Saturday 05/23
$75
Sunday 05/24
$75
Monday 05/25
$75
Tuesday 05/26
$75
Wednesday 05/27
$75
Thursday 05/28
$75
Friday 05/29
$75
Saturday 05/30

The cheapest time to travel from Santiago del Estero to Mendoza

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago del Estero to Mendoza, for the next 30 days.
With a price starting from $75, Sunday is the cheapest day for a bus from Santiago del Estero to Mendoza. Sunday instead is the most expensive day with prices starting from $75.
Night is the cheapest day time for bus tickets from Santiago del Estero to Mendoza, with $75. Afternoon is the most expensive time of the day with prices starting from $76.

How to save money travelling from Santiago del Estero to Mendoza

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago del Estero to Mendoza in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago del Estero to Mendoza, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago del Estero to Mendoza are also emptier.

Beloved bus companies from Santiago del Estero to Mendoza

These are the most booked bus companies between Santiago del Estero to Mendoza from our users.

Autotransportes San Juan from Santiago del Estero to Mendoza

Autotransportes San Juan

Here you will find the key facts about the Autotransportes San Juan bus route Santiago del Estero to Mendoza:

Cheapest Price $75
Fastest Bus 17h 20m
Earliest Bus 12:20 AM
Last Bus 12:20 AM
Daily Connections 5 Ø
Found on 4/21/2026

All bus stations and stops in Santiago del Estero and Mendoza

In the map below, you can see where to find all bus stations in Santiago del Estero and Mendoza.

Service and Comfort on the bus from Santiago del Estero to Mendoza

Want to know which seat classes are available on the buses from Santiago del Estero to Mendoza? Or which bus companies serve the route Santiago del Estero to Mendoza? Below you will find answers to your questions.

FAQs about the Santiago del Estero to Mendoza bus

How much does a Santiago del Estero Mendoza bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $75 and takes 17h 20m to reach Mendoza. Compare offers to save money!

How much could I save by comparing buses from Santiago del Estero to Mendoza?

This route is offered by 2 companies with a range of ticket prices between $75 and $92. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Mendoza.

On average, how many connections are available from Santiago del Estero to Mendoza each day?

Every day, the Santiago del Estero to Mendoza bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago del Estero to Mendoza take?

The fastest bus from Santiago del Estero to Mendoza is offered by Andesmar and takes 16h 23m. Bus tickets for this connection cost $92. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago del Estero to Mendoza?

The earliest bus arriving in Mendoza from Santiago del Estero starts at 12:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago del Estero to Mendoza?

The latest bus trip departing from Santiago del Estero for Mendoza starts at 4:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago del Estero Mendoza route?

When traveling by bus from Santiago del Estero to Mendoza, passengers can travel with Andesmar and Autotransportes San Juan. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago del Estero and Mendoza?

You can check all the direct connections between Santiago del Estero and Mendoza by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Andesmar and Autotransportes San Juan.

What can I take with me on the Santiago del Estero to Mendoza bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago del Estero Mendoza bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago del Estero Mendoza bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago del Estero to Mendoza on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago del Estero to Mendoza?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 12 daily trips between Santiago del Estero and Mendoza. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago del Estero to Mendoza?

Prices and availability for 12 trips between Santiago del Estero and Mendoza change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago del Estero to Mendoza

Basic
Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Santiago del Estero and to Mendoza

Here’s an overview of the most popular bus routes to Santiago del Estero and to Mendoza. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Santiago del Estero from Río Gallegos Bus to Santiago del Estero from Río Gallegos
From San Miguel de Tucumán to Santiago del Estero bus From San Miguel de Tucumán to Santiago del Estero bus
Buses to Santiago del Estero from Córdoba, CD Buses to Santiago del Estero from Córdoba, CD
Bus Buenos Aires - Santiago del Estero Bus Buenos Aires - Santiago del Estero
Bus Luján de Cuyo, MZ to Mendoza Bus Luján de Cuyo, MZ to Mendoza
Buses Lujan, BA to Mendoza Buses Lujan, BA to Mendoza
Bus to Mendoza from San Fernando del Valle de Catamarca Bus to Mendoza from San Fernando del Valle de Catamarca
Buses from Mar del Plata to Mendoza Buses from Mar del Plata to Mendoza
CheckMyBus › Buses in Argentina › Bus to Santiago del Estero › Bus to Mendoza

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