What is the best way to travel from Lyon to Rome?
Looking for a trip? Compare all the available Buses and Flights for the journey to Rome from Lyon. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Lyon?
You can get to Rome with just $40 by taking a Bus from Itabus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/14/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/14/2025 11:45:00 PM. 50 Premium Economy ticket for $46 per person are available. Travel duration is 14h 30m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/14/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/14/2025 11:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 14h 10m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/14/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/15/2025 12:15:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 15h 30m
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Skyscanner1h 35m08:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 8:00:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/14/2025 9:35:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 1h 35m
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EasyJet Airline1h 35m08:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 8:00:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/14/2025 9:35:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 1h 35m
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Air Nostrum7h 45m06:10 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station1:55 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Nostrum goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 6:10:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/14/2025 1:55:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 7h 45m
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Air Malta22h 40m09:30 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:10 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 9:30:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/15/2025 8:10:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 22h 40m
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Air Bagan19h 25m02:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:45 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Air Bagan goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 2:20:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/15/2025 9:45:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 19h 25m
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Vueling Airlines8h 35m011:30 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:05 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 11:30:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/15/2025 8:05:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 8h 35m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/15/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/15/2025 11:45:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 14h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/15/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/16/2025 7:00:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 15h 30m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/15/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/15/2025 11:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 14h 10m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/15/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/16/2025 12:15:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 15h 30m
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STARSHIPPER SAS17h 40m02:10 PMLyons St. Exupery AirportLyons St. Exupery Airport7:50 AMRomeTiburtina Bus Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 12/15/2025 2:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/16/2025 7:50:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 17h 40m
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EasyJet Airline1h 30m07:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:35 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 7:05:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/15/2025 8:35:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 1h 30m
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LC Perú12h 30m08:35 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:05 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 8:35:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/15/2025 9:05:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 30m
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LC Perú7h 25m08:35 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station4:00 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 8:35:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/15/2025 4:00:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 7h 25m
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Vueling Airlines4h 35m08:15 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station12:50 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 8:15:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/16/2025 12:50:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 4h 35m
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Air Nostrum13h 20m06:10 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station7:30 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Nostrum goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 6:10:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/15/2025 7:30:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 13h 20m
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KLM - Royal Dutch Airlines5h 15m02:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station7:25 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from KLM - Royal Dutch Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 2:10:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/15/2025 7:25:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 5h 15m
Cheapest Buses Monday
Cheapest Flights Monday
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/16/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/16/2025 11:45:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 14h 30m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/16/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/16/2025 11:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 14h 10m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/16/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/16/2025 4:05:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 14h 50m
Cheapest Buses Tuesday
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/17/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/17/2025 11:45:00 PM. 50 Premium Economy ticket for $53 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/17/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/17/2025 4:05:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 14h 50m
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FlixBus16h 50m01:15 AMLyonPerrache Bus Stop6:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/17/2025 1:15:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/17/2025 6:05:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 50m
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FlixBus16h 0m06:00 PMLyonPerrache Bus Stop10:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/17/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 10:00:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 16h 0m
Cheapest Buses Wednesday
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/18/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 11:45:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 14h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/18/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 7:00:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 15h 30m
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FlixBus17h 5m08:05 AMLyonPerrache Bus Stop1:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/18/2025 8:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 1:10:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 17h 5m
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FlixBus17h 5m011:00 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/18/2025 11:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 4:05:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 17h 5m
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EasyJet Airline1h 35m07:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:10 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 7:35:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 9:10:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 1h 35m
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Skyscanner1h 35m07:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:10 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 7:35:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 9:10:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 1h 35m
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LC Perú5h 25m08:35 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station2:00 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 8:35:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/18/2025 2:00:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 5h 25m
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Air Malta10h 15m09:30 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station7:45 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 9:30:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/19/2025 7:45:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 10h 15m
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Vueling Airlines5h 45m08:15 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station2:00 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 8:15:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 2:00:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 5h 45m
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Hop!5h 20m05:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:10 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Hop! goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 5:50:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 11:10:00 PM. 50 Economy ticket for $296 per person are available. Travel duration is 5h 20m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/19/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 7:00:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 15h 30m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/19/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 4:05:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 14h 50m
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FlixBus16h 45m01:15 AMLyonPerrache Bus Stop6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/19/2025 1:15:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/19/2025 6:00:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 16h 45m
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STARSHIPPER SAS21h 40m02:10 PMLyons St. Exupery AirportLyons St. Exupery Airport11:50 AMRomeTiburtina Bus Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 12/19/2025 2:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 11:50:00 AM. 50 Economy ticket for $184 per person are available. Travel duration is 21h 40m
Cheapest Buses Friday
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Itabus19h 50m011:50 PMLyonPerrache Bus Stop7:40 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/20/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 7:40:00 PM. 50 Premium Economy ticket for $62 per person are available. Travel duration is 19h 50m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/20/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 11:45:00 PM. 50 Premium Economy ticket for $69 per person are available. Travel duration is 14h 30m
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FlixBus16h 5m02:55 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/20/2025 2:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 7:00:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 16h 5m
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FlixBus15h 50m04:00 PMLyonPerrache Bus Stop7:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/20/2025 4:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 7:50:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 15h 50m
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Volotea7h 10m02:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:20 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 2:10:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/20/2025 9:20:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 7h 10m
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Vueling Airlines6h 10m08:15 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station2:25 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 8:15:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/20/2025 2:25:00 PM. 50 Economy ticket for $275 per person are available. Travel duration is 6h 10m
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EasyJet Airline4h 30m08:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station12:30 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 8:00:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/20/2025 12:30:00 PM. 50 Economy ticket for $353 per person are available. Travel duration is 4h 30m
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Skyscanner1h 35m012:40 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station2:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 12:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/20/2025 2:15:00 PM. 50 Economy ticket for $386 per person are available. Travel duration is 1h 35m
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Aer Lingus17h 30m05:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:40 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Aer Lingus goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 5:10:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/21/2025 10:40:00 AM. 50 Economy ticket for $406 per person are available. Travel duration is 17h 30m
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British Airways13h 40m09:45 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:25 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from British Airways goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 9:45:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/21/2025 11:25:00 AM. 50 Economy ticket for $417 per person are available. Travel duration is 13h 40m
Cheapest Buses Saturday
Cheapest Flights Saturday
What are the fastest trips from Lyon to Rome?
You can get to Rome from Lyon in just 1h 30m with a Flight from EasyJet Airline. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Skyscanner1h 35m08:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 8:00:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/14/2025 9:35:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 1h 35m
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EasyJet Airline1h 35m08:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 8:00:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/14/2025 9:35:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 1h 35m
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Air Nostrum7h 45m06:10 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station1:55 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Nostrum goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 6:10:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/14/2025 1:55:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 7h 45m
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Vueling Airlines8h 35m011:30 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:05 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 11:30:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/15/2025 8:05:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 8h 35m
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EasyJet Airline16h 55m04:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:45 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 4:50:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/15/2025 9:45:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 16h 55m
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Transavia France18h 40m03:25 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:05 AMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Transavia France goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/14/2025 3:25:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/15/2025 10:05:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 18h 40m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/14/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/14/2025 11:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 14h 10m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/14/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/14/2025 11:45:00 PM. 50 Premium Economy ticket for $46 per person are available. Travel duration is 14h 30m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/14/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/15/2025 12:15:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 15h 30m
Fastest Flights Sunday
Fastest Buses Sunday
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EasyJet Airline1h 30m07:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:35 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 7:05:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/15/2025 8:35:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 1h 30m
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Vueling Airlines4h 35m08:15 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station12:50 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 8:15:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/16/2025 12:50:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 4h 35m
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KLM - Royal Dutch Airlines5h 15m02:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station7:25 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from KLM - Royal Dutch Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 2:10:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/15/2025 7:25:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 5h 15m
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LC Perú7h 25m08:35 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station4:00 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 8:35:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/15/2025 4:00:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 7h 25m
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LC Perú12h 30m08:35 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:05 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 8:35:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/15/2025 9:05:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 30m
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Air Nostrum13h 20m06:10 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station7:30 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Nostrum goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/15/2025 6:10:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/15/2025 7:30:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 13h 20m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/15/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/15/2025 11:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 14h 10m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/15/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/15/2025 11:45:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 14h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/15/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/16/2025 7:00:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/15/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/16/2025 12:15:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 15h 30m
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STARSHIPPER SAS17h 40m02:10 PMLyons St. Exupery AirportLyons St. Exupery Airport7:50 AMRomeTiburtina Bus Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 12/15/2025 2:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/16/2025 7:50:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 17h 40m
Fastest Flights Monday
Fastest Buses Monday
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/16/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/16/2025 11:45:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 14h 10m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/16/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/16/2025 11:45:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/16/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/16/2025 4:05:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 14h 50m
Fastest Buses Tuesday
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/17/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/17/2025 11:45:00 PM. 50 Premium Economy ticket for $53 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/17/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/17/2025 4:05:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 14h 50m
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FlixBus16h 0m06:00 PMLyonPerrache Bus Stop10:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/17/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 10:00:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 16h 0m
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FlixBus16h 50m01:15 AMLyonPerrache Bus Stop6:05 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/17/2025 1:15:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/17/2025 6:05:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 50m
Fastest Buses Wednesday
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EasyJet Airline1h 35m07:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:10 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 7:35:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 9:10:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 1h 35m
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Skyscanner1h 35m07:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:10 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 7:35:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 9:10:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 1h 35m
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Hop!5h 20m05:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:10 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Hop! goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 5:50:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 11:10:00 PM. 50 Economy ticket for $296 per person are available. Travel duration is 5h 20m
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LC Perú5h 25m08:35 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station2:00 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 8:35:00 AM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/18/2025 2:00:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 5h 25m
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Vueling Airlines5h 45m08:15 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station2:00 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 8:15:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/18/2025 2:00:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 5h 45m
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Air Malta10h 15m09:30 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station7:45 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/18/2025 9:30:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/19/2025 7:45:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 10h 15m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/18/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/18/2025 11:45:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 14h 30m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/18/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 7:00:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 15h 30m
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FlixBus17h 5m08:05 AMLyonPerrache Bus Stop1:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/18/2025 8:05:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 1:10:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 17h 5m
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FlixBus17h 5m011:00 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/18/2025 11:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 4:05:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 17h 5m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/19/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/19/2025 4:05:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 14h 50m
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Itabus15h 30m03:30 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/19/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 7:00:00 AM. 50 Premium Economy ticket for $59 per person are available. Travel duration is 15h 30m
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FlixBus16h 45m01:15 AMLyonPerrache Bus Stop6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/19/2025 1:15:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/19/2025 6:00:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 16h 45m
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STARSHIPPER SAS21h 40m02:10 PMLyons St. Exupery AirportLyons St. Exupery Airport11:50 AMRomeTiburtina Bus Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 12/19/2025 2:10:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 11:50:00 AM. 50 Economy ticket for $184 per person are available. Travel duration is 21h 40m
Fastest Buses Friday
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Skyscanner1h 35m012:40 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station2:15 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 12:40:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/20/2025 2:15:00 PM. 50 Economy ticket for $386 per person are available. Travel duration is 1h 35m
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EasyJet Airline4h 30m08:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station12:30 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 8:00:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/20/2025 12:30:00 PM. 50 Economy ticket for $353 per person are available. Travel duration is 4h 30m
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Vueling Airlines6h 10m08:15 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station2:25 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 8:15:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/20/2025 2:25:00 PM. 50 Economy ticket for $275 per person are available. Travel duration is 6h 10m
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Volotea7h 10m02:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:20 PMRome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 2:10:00 PM to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 12/20/2025 9:20:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 7h 10m
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British Airways13h 40m09:45 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:25 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from British Airways goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 9:45:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/21/2025 11:25:00 AM. 50 Economy ticket for $417 per person are available. Travel duration is 13h 40m
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Aer Lingus17h 30m05:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:40 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Aer Lingus goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 12/20/2025 5:10:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/21/2025 10:40:00 AM. 50 Economy ticket for $406 per person are available. Travel duration is 17h 30m
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Itabus14h 30m09:15 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/20/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/20/2025 11:45:00 PM. 50 Premium Economy ticket for $69 per person are available. Travel duration is 14h 30m
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FlixBus15h 50m04:00 PMLyonPerrache Bus Stop7:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/20/2025 4:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 7:50:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 15h 50m
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FlixBus16h 5m02:55 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/20/2025 2:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 7:00:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 16h 5m
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Itabus19h 50m011:50 PMLyonPerrache Bus Stop7:40 PMRomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/20/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/21/2025 7:40:00 PM. 50 Premium Economy ticket for $62 per person are available. Travel duration is 19h 50m
Fastest Flights Saturday
Fastest Buses Saturday
Here you will find all operators and timetables for a
Bus from Lyon to Rome
What are the most popular stations in Lyon and Rome?
In Lyon, you will usually depart from Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, while in Rome you will be arriving at Termini Bus Station, Termini Central Station or Ostiense Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Lyon? With 9 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Rome, you can pay as low as $40 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from EasyJet Airline: you will get to Rome in just 1h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Rome are Itabus, FlixBus and EasyJet Airline, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Settebagni, and look at flights from Lyons St. Exupery Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Rome?
The most popular companies between Lyon and Rome, are Itabus, FlixBus and EasyJet Airline. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus, FlixBus and STARSHIPPER SAS
Airlines: EasyJet Airline, LC Perú, Vueling Airlines and 10 more.
All you need to know when you travel from Lyon to Rome
Check all information on comfort and services on all modes of transports from Lyon to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Rome
How can I reach Rome from Lyon?
Every day, there are on average 9 connections between Bus and Flight, with which you can get to Rome from Lyon.
How far is Rome from Lyon?
The distance between Lyon and Rome is 465.5 miles.
What is the most ecofriendly mode of transport between Lyon and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 127 kgs, and a flight 184 kgs.
What is the cheapest mode of transport from Lyon to Rome?
You can get to Rome with just $40 by taking a Bus from Itabus.
What is the fastest way to get from Lyon to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 30m with a Flight from EasyJet Airline.
More routes to Lyon and to Rome
Looking for more options? Here you can see the most popular routes to Lyon and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Barcelona to Lyon
- Bern to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Braga to Lyon
- Caen to Lyon
- Dijon to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Grenoble to Lyon
- Lisbon to Lyon
- Lloret de Mar to Lyon
- London to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille to Lyon
- Milan to Lyon
- Paris to Lyon
- Rome to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Trips to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitanova to Rome
- Foggia to Rome
- Genoa to Rome
- L'Aquila to Rome
- Lamezia Terme to Rome
- Lecce to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Palermo to Rome
- Perugia to Rome
- Pescara to Rome
- Porto D'Ascoli to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Venice to Rome

