What is the best way to travel from Lyon to Rome?
Looking for a trip? Compare all the available Buses and Flights for the journey to Rome from Lyon. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Lyon?
You can get to Rome with just $57 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus16h 0m06:00 PMLyonPerrache Bus Stop10:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/19/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/20/2025 10:00:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 16h 0m
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FlixBus16h 6m011:59 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/19/2025 11:59:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/20/2025 4:05:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 16h 6m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/19/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/19/2025 4:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 14h 50m
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FlixBus17h 20m06:15 AMLyonPerrache Bus Stop11:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/19/2025 6:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/19/2025 11:35:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 20m
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FlixBus17h 35m012:35 PMLyonPerrache Bus Stop6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/19/2025 12:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/20/2025 6:10:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 17h 35m
Cheapest Buses Wednesday
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FlixBus16h 6m011:59 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/20/2025 11:59:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/21/2025 4:05:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 16h 6m
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FlixBus17h 20m06:15 AMLyonPerrache Bus Stop11:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/20/2025 6:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/20/2025 11:35:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 17h 20m
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FlixBus16h 0m08:45 PMLyonPerrache Bus Stop12:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/20/2025 8:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/21/2025 12:45:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 0m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/20/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/21/2025 12:15:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 15h 30m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/20/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/20/2025 4:05:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 14h 50m
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EasyJet Airline1h 35m07:05 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:40 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/20/2025 7:05:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/20/2025 8:40:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 1h 35m
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Iberia Express27h 15m09:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station12:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia Express goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/20/2025 9:00:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/22/2025 12:15:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 27h 15m
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LC Perú1h 35m08:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:00 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/20/2025 8:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/20/2025 10:00:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 1h 35m
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Air France5h 25m010:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station3:50 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air France goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/20/2025 10:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/20/2025 3:50:00 PM. 50 Economy ticket for $207 per person are available. Travel duration is 5h 25m
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Hop!5h 40m011:45 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station5:25 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Hop! goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/20/2025 11:45:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/20/2025 5:25:00 PM. 50 Economy ticket for $207 per person are available. Travel duration is 5h 40m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/21/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/21/2025 4:05:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 50m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/21/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/21/2025 11:45:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 10m
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FlixBus18h 1m011:59 PMLyonPerrache Bus Stop6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/21/2025 11:59:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/22/2025 6:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 18h 1m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/21/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/22/2025 12:15:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 15h 30m
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FlixBus15h 35m010:55 PMLyonPerrache Bus Stop2:30 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/21/2025 10:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/22/2025 2:30:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 15h 35m
Cheapest Buses Friday
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FlixBus17h 30m012:35 PMLyonPerrache Bus Stop6:05 AMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/22/2025 12:35:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/23/2025 6:05:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 17h 30m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/22/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/22/2025 11:45:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 10m
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FlixBus17h 20m06:15 AMLyonPerrache Bus Stop11:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/22/2025 6:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/22/2025 11:35:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 17h 20m
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FlixBus16h 0m08:45 PMLyonPerrache Bus Stop12:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/22/2025 8:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/23/2025 12:45:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 0m
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FlixBus16h 6m011:59 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/22/2025 11:59:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/23/2025 4:05:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 6m
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Wizz Air22h 50m08:20 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station7:10 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/22/2025 8:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/23/2025 7:10:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 22h 50m
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EasyJet Airline1h 30m07:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:55 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/22/2025 7:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/22/2025 8:55:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 1h 30m
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Volotea10h 0m06:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station4:00 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/22/2025 6:00:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/22/2025 4:00:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 10h 0m
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Air Nostrum6h 25m06:10 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station12:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Nostrum goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/22/2025 6:10:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/22/2025 12:35:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 6h 25m
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Lufthansa26h 30m06:20 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:50 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Lufthansa goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/22/2025 6:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/23/2025 8:50:00 AM. 50 Economy ticket for $206 per person are available. Travel duration is 26h 30m
Cheapest Buses Saturday
Cheapest Flights Saturday
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/23/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/23/2025 4:05:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 14h 50m
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FlixBus16h 55m06:55 PMLyonPerrache Bus Stop11:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/23/2025 6:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/24/2025 11:50:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 16h 55m
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FlixBus15h 35m010:55 PMLyonPerrache Bus Stop2:30 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/23/2025 10:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/24/2025 2:30:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 15h 35m
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FlixBus16h 0m08:45 PMLyonPerrache Bus Stop12:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/23/2025 8:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/24/2025 12:45:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 16h 0m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/23/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/23/2025 11:45:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 14h 10m
Cheapest Buses Sunday
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FlixBus17h 20m06:15 AMLyonPerrache Bus Stop11:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/24/2025 6:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/24/2025 11:35:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 17h 20m
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FlixBus16h 0m08:45 PMLyonPerrache Bus Stop12:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/24/2025 8:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/25/2025 12:45:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 16h 0m
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FlixBus16h 5m010:55 PMLyonPerrache Bus Stop3:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/24/2025 10:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/25/2025 3:00:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 16h 5m
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FlixBus16h 45m01:15 AMLyonPerrache Bus Stop6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/24/2025 1:15:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 3/24/2025 6:00:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 16h 45m
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FlixBus17h 30m012:35 PMLyonPerrache Bus Stop6:05 AMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/24/2025 12:35:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/25/2025 6:05:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 17h 30m
Cheapest Buses Monday
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/25/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/25/2025 11:45:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 14h 10m
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FlixBus16h 5m010:55 PMLyonPerrache Bus Stop3:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/25/2025 10:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/26/2025 3:00:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 5m
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FlixBus16h 6m011:59 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/25/2025 11:59:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/26/2025 4:05:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 16h 6m
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FlixBus16h 45m01:15 AMLyonPerrache Bus Stop6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/25/2025 1:15:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 3/25/2025 6:00:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 16h 45m
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FlixBus16h 20m02:40 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/25/2025 2:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/26/2025 7:00:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 16h 20m
Cheapest Buses Tuesday
What are the fastest trips from Lyon to Rome?
You can get to Rome from Lyon in just 1h 30m with a Flight from EasyJet Airline. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/19/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/19/2025 4:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 14h 50m
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FlixBus16h 0m06:00 PMLyonPerrache Bus Stop10:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/19/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/20/2025 10:00:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 16h 0m
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FlixBus16h 6m011:59 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/19/2025 11:59:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/20/2025 4:05:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 16h 6m
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FlixBus17h 20m06:15 AMLyonPerrache Bus Stop11:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/19/2025 6:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/19/2025 11:35:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 20m
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FlixBus17h 35m012:35 PMLyonPerrache Bus Stop6:10 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/19/2025 12:35:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/20/2025 6:10:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 17h 35m
Fastest Buses Wednesday
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EasyJet Airline1h 35m07:05 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:40 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/20/2025 7:05:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/20/2025 8:40:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 1h 35m
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LC Perú1h 35m08:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:00 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/20/2025 8:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/20/2025 10:00:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 1h 35m
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Air France5h 25m010:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station3:50 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air France goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/20/2025 10:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/20/2025 3:50:00 PM. 50 Economy ticket for $207 per person are available. Travel duration is 5h 25m
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Hop!5h 40m011:45 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station5:25 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Hop! goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/20/2025 11:45:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/20/2025 5:25:00 PM. 50 Economy ticket for $207 per person are available. Travel duration is 5h 40m
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Iberia Express27h 15m09:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station12:15 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia Express goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/20/2025 9:00:00 PM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/22/2025 12:15:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 27h 15m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/20/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/20/2025 4:05:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 14h 50m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/20/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/21/2025 12:15:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 15h 30m
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FlixBus16h 0m08:45 PMLyonPerrache Bus Stop12:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/20/2025 8:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/21/2025 12:45:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 0m
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FlixBus16h 6m011:59 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/20/2025 11:59:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/21/2025 4:05:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 16h 6m
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FlixBus17h 20m06:15 AMLyonPerrache Bus Stop11:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/20/2025 6:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/20/2025 11:35:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 17h 20m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/21/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/21/2025 11:45:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 10m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/21/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/21/2025 4:05:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 14h 50m
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FlixBus15h 30m08:45 PMLyonPerrache Bus Stop12:15 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/21/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/22/2025 12:15:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 15h 30m
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FlixBus15h 35m010:55 PMLyonPerrache Bus Stop2:30 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/21/2025 10:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/22/2025 2:30:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 15h 35m
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FlixBus18h 1m011:59 PMLyonPerrache Bus Stop6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/21/2025 11:59:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/22/2025 6:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 18h 1m
Fastest Buses Friday
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EasyJet Airline1h 30m07:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:55 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/22/2025 7:25:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/22/2025 8:55:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 1h 30m
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Air Nostrum6h 25m06:10 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station12:35 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Nostrum goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/22/2025 6:10:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/22/2025 12:35:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 6h 25m
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Volotea10h 0m06:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station4:00 PMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/22/2025 6:00:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/22/2025 4:00:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 10h 0m
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Wizz Air22h 50m08:20 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station7:10 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/22/2025 8:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/23/2025 7:10:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 22h 50m
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Lufthansa26h 30m06:20 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:50 AMRome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Lufthansa goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 3/22/2025 6:20:00 AM to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 3/23/2025 8:50:00 AM. 50 Economy ticket for $206 per person are available. Travel duration is 26h 30m
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/22/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/22/2025 11:45:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 10m
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FlixBus16h 0m08:45 PMLyonPerrache Bus Stop12:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/22/2025 8:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/23/2025 12:45:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 0m
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FlixBus16h 6m011:59 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/22/2025 11:59:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/23/2025 4:05:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 6m
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FlixBus17h 20m06:15 AMLyonPerrache Bus Stop11:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/22/2025 6:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/22/2025 11:35:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 17h 20m
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FlixBus17h 30m012:35 PMLyonPerrache Bus Stop6:05 AMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/22/2025 12:35:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/23/2025 6:05:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 17h 30m
Fastest Flights Saturday
Fastest Buses Saturday
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/23/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/23/2025 11:45:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 14h 10m
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FlixBus14h 50m01:15 AMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/23/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/23/2025 4:05:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 14h 50m
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FlixBus15h 35m010:55 PMLyonPerrache Bus Stop2:30 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/23/2025 10:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/24/2025 2:30:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 15h 35m
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FlixBus16h 0m08:45 PMLyonPerrache Bus Stop12:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/23/2025 8:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/24/2025 12:45:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 16h 0m
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FlixBus16h 55m06:55 PMLyonPerrache Bus Stop11:50 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/23/2025 6:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/24/2025 11:50:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 16h 55m
Fastest Buses Sunday
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FlixBus16h 0m08:45 PMLyonPerrache Bus Stop12:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/24/2025 8:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/25/2025 12:45:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 16h 0m
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FlixBus16h 5m010:55 PMLyonPerrache Bus Stop3:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/24/2025 10:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/25/2025 3:00:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 16h 5m
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FlixBus16h 45m01:15 AMLyonPerrache Bus Stop6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/24/2025 1:15:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 3/24/2025 6:00:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 16h 45m
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FlixBus17h 20m06:15 AMLyonPerrache Bus Stop11:35 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/24/2025 6:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/24/2025 11:35:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 17h 20m
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FlixBus17h 30m012:35 PMLyonPerrache Bus Stop6:05 AMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/24/2025 12:35:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 3/25/2025 6:05:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 17h 30m
Fastest Buses Monday
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FlixBus14h 10m09:35 AMLyonPerrache Bus Stop11:45 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/25/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 3/25/2025 11:45:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 14h 10m
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FlixBus16h 5m010:55 PMLyonPerrache Bus Stop3:00 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/25/2025 10:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/26/2025 3:00:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 5m
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FlixBus16h 6m011:59 PMLyonPerrache Bus Stop4:05 PMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/25/2025 11:59:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/26/2025 4:05:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 16h 6m
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FlixBus16h 20m02:40 PMLyonPerrache Bus Stop7:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/25/2025 2:40:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 3/26/2025 7:00:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 16h 20m
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FlixBus16h 45m01:15 AMLyonPerrache Bus Stop6:00 PMRomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 3/25/2025 1:15:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 3/25/2025 6:00:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 16h 45m
Fastest Buses Tuesday
Here you will find all operators and timetables for a
Bus from Lyon to Rome
What are the most popular stations in Lyon and Rome?
In Lyon, you will usually depart from Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, while in Rome you will be arriving at Tiburtina Bus Station, Anagnina Bus Station or Termini Central Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Lyon? With 6 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Rome, you can pay as low as $57 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from EasyJet Airline: you will get to Rome in just 1h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Rome are FlixBus, EasyJet Airline and Iberia Express, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Settebagni, and look at flights from Lyons St. Exupery Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Rome?
The most popular companies between Lyon and Rome, are FlixBus, EasyJet Airline and Iberia Express. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: EasyJet Airline, Iberia Express, LC Perú and 6 more.
All you need to know when you travel from Lyon to Rome
Check all information on comfort and services on all modes of transports from Lyon to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Rome
How can I reach Rome from Lyon?
Every day, there are on average 6 connections between Bus and Flight, with which you can get to Rome from Lyon.
How far is Rome from Lyon?
The distance between Lyon and Rome is 465.5 miles.
What is the most ecofriendly mode of transport between Lyon and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 127 kgs, and a flight 184 kgs.
What is the cheapest mode of transport from Lyon to Rome?
You can get to Rome with just $57 by taking a Bus from FlixBus.
What is the fastest way to get from Lyon to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 30m with a Flight from EasyJet Airline.
More routes to Lyon and to Rome
Looking for more options? Here you can see the most popular routes to Lyon and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Alicante to Lyon
- Barcelona to Lyon
- Basel to Lyon
- Bordeaux to Lyon
- Brive-la-Gaillarde to Lyon
- Brussels to Lyon
- Deauville to Lyon
- Frankfurt am Main to Lyon
- Geneva Airport to Lyon
- Geneva to Lyon
- Lausanne to Lyon
- Le Havre to Lyon
- London to Lyon
- Madrid to Lyon
- Marseille to Lyon
- Milan to Lyon
- Nantes to Lyon
- Paris to Lyon
- Pau to Lyon
- Saint-Étienne to Lyon
- Toulon to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Trips to Rome
- Ascoli Piceno to Rome
- Battipaglia to Rome
- Benevento to Rome
- Catania to Rome
- Chieti to Rome
- Fisciano to Rome
- Florence to Rome
- L'Aquila to Rome
- Lanciano to Rome
- Maglie to Rome
- Milan to Rome
- Palermo to Rome
- Pescara to Rome
- Porto D'Ascoli to Rome
- Porto Recanati to Rome
- Porto San Giorgio to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- San Benedetto del Tronto to Rome
- Terni to Rome
- Vibo Valentia to Rome
- Villa Rosa to Rome
- Villa San Giovanni to Rome