Compare all timetables for the bus from Lyon to Rome
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 15h 30m | 8:45 PM | Lyon | Perrache Bus Stop | 12:15 PM | Rome | Anagnina Bus Station | Economy | $52 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/4/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/5/2025 12:15:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 15h 30m
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| Itabus | 14h 30m | 9:15 AM | Lyon | Perrache Bus Stop | 11:45 PM | Rome | Tiburtina Bus Station | Premium Economy | $52 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/4/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/4/2025 11:45:00 PM. 50 Premium Economy ticket for $52 per person are available. Travel duration is 14h 30m
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| Itabus | 15h 30m | 3:30 PM | Lyon | Perrache Bus Stop | 7:00 AM | Rome | Tiburtina Bus Station | Premium Economy | $71 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/4/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/5/2025 7:00:00 AM. 50 Premium Economy ticket for $71 per person are available. Travel duration is 15h 30m
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| FlixBus | 15h 45m | 10:50 AM | Lyon | Perrache Bus Stop | 2:35 AM | Rome | Tiburtina Bus Station | Economy | $80 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/4/2025 10:50:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/5/2025 2:35:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 15h 45m
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| FlixBus | 14h 50m | 1:15 AM | Lyon | Perrache Bus Stop | 4:05 PM | Rome | Tiburtina Bus Station | Economy | $83 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/4/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/4/2025 4:05:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 14h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 9:15 AM | Lyon | Perrache Bus Stop | 11:45 PM | Rome | Tiburtina Bus Station | Premium Economy | $45 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/5/2025 11:45:00 PM. 50 Premium Economy ticket for $45 per person are available. Travel duration is 14h 30m
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| FlixBus | 14h 10m | 9:35 AM | Lyon | Perrache Bus Stop | 11:45 PM | Rome | Tiburtina Bus Station | Economy | $52 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/5/2025 11:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 10m
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| FlixBus | 15h 30m | 8:45 PM | Lyon | Perrache Bus Stop | 12:15 PM | Rome | Anagnina Bus Station | Economy | $52 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/6/2025 12:15:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 15h 30m
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| Itabus | 15h 30m | 3:30 PM | Lyon | Perrache Bus Stop | 7:00 AM | Rome | Tiburtina Bus Station | Premium Economy | $71 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 7:00:00 AM. 50 Premium Economy ticket for $71 per person are available. Travel duration is 15h 30m
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| Itabus | 19h 50m | 11:50 PM | Lyon | Perrache Bus Stop | 7:40 PM | Rome | Tiburtina Bus Station | Economy | $87 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 7:40:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 19h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 9:15 AM | Lyon | Perrache Bus Stop | 11:45 PM | Rome | Tiburtina Bus Station | Premium Economy | $40 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 11:45:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 14h 30m
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| FlixBus | 14h 10m | 9:35 AM | Lyon | Perrache Bus Stop | 11:45 PM | Rome | Tiburtina Bus Station | Economy | $52 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/6/2025 11:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 10m
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| FlixBus | 15h 30m | 8:45 PM | Lyon | Perrache Bus Stop | 12:15 PM | Rome | Anagnina Bus Station | Economy | $52 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 8:45:00 PM to Anagnina Bus Station, Rome (Italy) arriving at 12/7/2025 12:15:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 15h 30m
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| Itabus | 15h 30m | 3:30 PM | Lyon | Perrache Bus Stop | 7:00 AM | Rome | Tiburtina Bus Station | Premium Economy | $52 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 7:00:00 AM. 50 Premium Economy ticket for $52 per person are available. Travel duration is 15h 30m
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| FlixBus | 16h 5m | 2:55 PM | Lyon | Perrache Bus Stop | 7:00 AM | Rome | Tiburtina Bus Station | Economy | $67 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 2:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 7:00:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 16h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 9:15 AM | Lyon | Perrache Bus Stop | 11:45 PM | Rome | Tiburtina Bus Station | Economy | $45 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/7/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 11:45:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 14h 30m
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| FlixBus | 14h 10m | 9:35 AM | Lyon | Perrache Bus Stop | 11:45 PM | Rome | Tiburtina Bus Station | Economy | $52 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/7/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 11:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 10m
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| Itabus | 15h 30m | 3:30 PM | Lyon | Perrache Bus Stop | 7:00 AM | Rome | Tiburtina Bus Station | Premium Economy | $52 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/7/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 7:00:00 AM. 50 Premium Economy ticket for $52 per person are available. Travel duration is 15h 30m
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| Itabus | 19h 50m | 11:50 PM | Lyon | Perrache Bus Stop | 7:40 PM | Rome | Tiburtina Bus Station | Basic | $57 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/7/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 7:40:00 PM. 50 Basic ticket for $57 per person are available. Travel duration is 19h 50m
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| FlixBus | 14h 50m | 1:15 AM | Lyon | Perrache Bus Stop | 4:05 PM | Rome | Tiburtina Bus Station | Economy | $71 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/7/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 4:05:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 14h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 9:15 AM | Lyon | Perrache Bus Stop | 11:45 PM | Rome | Tiburtina Bus Station | Premium Economy | $52 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/8/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 11:45:00 PM. 50 Premium Economy ticket for $52 per person are available. Travel duration is 14h 30m
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| Itabus | 19h 50m | 11:50 PM | Lyon | Perrache Bus Stop | 7:40 PM | Rome | Tiburtina Bus Station | Premium Economy | $63 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/8/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 7:40:00 PM. 50 Premium Economy ticket for $63 per person are available. Travel duration is 19h 50m
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| Itabus | 15h 30m | 3:30 PM | Lyon | Perrache Bus Stop | 7:00 AM | Rome | Tiburtina Bus Station | Premium Economy | $64 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/8/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 7:00:00 AM. 50 Premium Economy ticket for $64 per person are available. Travel duration is 15h 30m
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| FlixBus | 16h 45m | 1:15 AM | Lyon | Perrache Bus Stop | 6:00 PM | Rome | Anagnina Bus Station | Economy | $100 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/8/2025 1:15:00 AM to Anagnina Bus Station, Rome (Italy) arriving at 12/8/2025 6:00:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 16h 45m
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| FlixBus | 14h 50m | 1:15 AM | Lyon | Perrache Bus Stop | 4:05 PM | Rome | Tiburtina Bus Station | Economy | $105 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/8/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/8/2025 4:05:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 14h 50m
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BlaBlaCar Bus16h 20m02:40 PMLyonPerrache Train Station11:50 PMGenoaFanti d'Italia / Principe Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/6/2025 2:40:00 PM to Fanti d'Italia / Principe Bus Stop, Genoa (Italy) arriving at 12/6/2025 11:50:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 9h 10m
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FlixBus7h 5m011:55 PMGenoaFanti d'Italia / Principe Bus Stop7:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Fanti d'Italia / Principe Bus Stop, Genoa (Italy) at 12/6/2025 11:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 7:00:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 7h 5m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 14h 10m | 9:35 AM | Lyon | Perrache Bus Stop | 11:45 PM | Rome | Tiburtina Bus Station | Economy | $52 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 9:35:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 11:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 10m
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| Itabus | 15h 30m | 3:30 PM | Lyon | Perrache Bus Stop | 7:00 AM | Rome | Tiburtina Bus Station | Premium Economy | $52 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 7:00:00 AM. 50 Premium Economy ticket for $52 per person are available. Travel duration is 15h 30m
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| Itabus | 19h 50m | 11:50 PM | Lyon | Perrache Bus Stop | 7:40 PM | Rome | Tiburtina Bus Station | Premium Economy | $63 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 11:50:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 7:40:00 PM. 50 Premium Economy ticket for $63 per person are available. Travel duration is 19h 50m
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| Itabus | 14h 30m | 9:15 AM | Lyon | Perrache Bus Stop | 11:45 PM | Rome | Tiburtina Bus Station | Premium Economy | $64 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 11:45:00 PM. 50 Premium Economy ticket for $64 per person are available. Travel duration is 14h 30m
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| FlixBus | 14h 50m | 1:15 AM | Lyon | Perrache Bus Stop | 4:05 PM | Rome | Tiburtina Bus Station | Economy | $78 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/9/2025 4:05:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 14h 50m
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BlaBlaCar Bus16h 20m02:40 PMLyonPerrache Train Station11:50 PMGenoaFanti d'Italia / Principe Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 12/6/2025 2:40:00 PM to Fanti d'Italia / Principe Bus Stop, Genoa (Italy) arriving at 12/6/2025 11:50:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 9h 10m
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FlixBus7h 5m011:55 PMGenoaFanti d'Italia / Principe Bus Stop7:00 AMRomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Fanti d'Italia / Principe Bus Stop, Genoa (Italy) at 12/6/2025 11:55:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/7/2025 7:00:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 7h 5m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 9:15 AM | Lyon | Perrache Bus Stop | 11:45 PM | Rome | Tiburtina Bus Station | Premium Economy | $45 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 9:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 11:45:00 PM. 50 Premium Economy ticket for $45 per person are available. Travel duration is 14h 30m
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| Itabus | 15h 30m | 3:30 PM | Lyon | Perrache Bus Stop | 7:00 AM | Rome | Tiburtina Bus Station | Premium Economy | $45 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 3:30:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 7:00:00 AM. 50 Premium Economy ticket for $45 per person are available. Travel duration is 15h 30m
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| FlixBus | 14h 50m | 1:15 AM | Lyon | Perrache Bus Stop | 4:05 PM | Rome | Tiburtina Bus Station | Economy | $61 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 1:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 4:05:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 50m
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| FlixBus | 16h 0m | 6:00 PM | Lyon | Perrache Bus Stop | 10:00 AM | Rome | Tiburtina Bus Station | Economy | $80 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 6:00:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/11/2025 10:00:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 16h 0m
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| FlixBus | 17h 25m | 6:15 AM | Lyon | Perrache Bus Stop | 11:40 PM | Rome | Tiburtina Bus Station | Economy | $81 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 6:15:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/10/2025 11:40:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 17h 25m
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Best Price Offer: The price for the cheapest bus from Lyon to Rome is $40 on 12/6/2025. Flexible travelers save on ticket prices.
Frequency of bus connections between Lyon and Rome
Facts about the bus from Lyon to Rome
Compare all providers like Itabus and FlixBus that travel 19 times every day by bus from Lyon to Rome in one click! Book your bus ticket from Lyon to Rome starting from $40!
| Cheapest Bus | $40 |
| Fastest Bus | 14h 10m |
| Earliest Bus | 1:15 AM |
| Latest Bus | 6:00 PM |
| Daily Bus Routes | 19 Ø |
| Distance | 465.5 miles |
| Bus Companies | Itabus and FlixBus |
Cheapest bus connections from Lyon to Rome
Every day, 19 buses from 2 bus companies leave Lyon for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.
The cheapest time to travel from Lyon to Rome
How to save money travelling from Lyon to Rome
Book the ticket from Lyon to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lyon to Rome, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lyon to Rome are also emptier.All bus stations and stops in Lyon and Rome
In the map below, you can see where to find all bus stations in Lyon and Rome.
Service and Comfort on the bus from Lyon to Rome
FAQs about the Lyon to Rome bus
How much does a Lyon Rome bus trip cost?
How much could I save by comparing buses from Lyon to Rome?
On average, how many connections are available from Lyon to Rome each day?
How long does a bus journey from Lyon to Rome take?
What time is the first bus from Lyon to Rome?
What time is the last bus from Lyon to Rome?
Which bus companies operate the Lyon Rome route?
Is there a direct bus between Lyon and Rome?
What can I take with me on the Lyon to Rome bus route?
What equipment is available for the Lyon Rome bus route?
Available seat classes which are offered on the bus route Lyon to Rome
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
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