Bus from Lyon to Rome from $35

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Compare all timetables for the bus from Lyon to Rome

Here is a selection of the cheapest bus trips from the schedule from Lyon to Rome from various bus operators like FlixBus, Itabus or BlaBlaCar Bus for the next days.
today
from $40
tomorrow
from $58
Saturday
from $36
Sunday
from $51
Monday
from $40
Tuesday
from $46
Wednesday
from $35

Cheapest bus trips today

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $40
  • Itabus
    15h 30m
    0
    3:30 PM
    Lyon
    Perrache Bus Stop
    7:00 AM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $40
  • Itabus
    14h 30m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $51
  • FlixBus
    16h 5m
    0
    1:15 AM
    Lyon
    Perrache Bus Stop
    5:20 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $85
  • FlixBus
    15h 40m
    0
    8:05 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $95
  • Did you know that if you travel from Lyon to Rome via Turin, you can save more than $17? You can find the corresponding connections below.
    • Distribusion
      19h 15m
      0
      9:15 AM
      Lyon
      Perrache Bus Stop
      1:45 PM
      Turin
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $22
      • Waiting Time 4h 45m
    • Bookaway
      10h 0m
      0
      6:30 PM
      Turin
      Central Bus Station
      4:30 AM
      Rome
      Tiburtina Bus Station
      0
      Bookaway
      Economy
      $1
    Travel time is 4h 45m longer, but you will save $17

Cheapest bus trips tomorrow

Prices are for one way and one person
  • BlaBlaCar Bus
    14h 45m
    0
    5:30 AM
    Lyon
    Perrache Train Station
    8:15 PM
    Rome
    Tiburtina Bus Station
    0
    BlaBlaCar Bus
    Economy
    $58
  • Itabus
    14h 30m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $63
  • Itabus
    14h 30m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $68
  • FlixBus
    15h 30m
    0
    8:45 PM
    Lyon
    Perrache Bus Stop
    12:15 PM
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    $93
  • FlixBus
    14h 10m
    0
    9:35 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $102
  • Did you know that if you travel from Lyon to Rome via Turin, you can save more than $35? You can find the corresponding connections below.
    • Distribusion
      19h 15m
      0
      9:15 AM
      Lyon
      Perrache Bus Stop
      1:45 PM
      Turin
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $22
      • Waiting Time 4h 45m
    • Bookaway
      10h 0m
      0
      6:30 PM
      Turin
      Central Bus Station
      4:30 AM
      Rome
      Tiburtina Bus Station
      0
      Bookaway
      Economy
      $1
    Travel time is 5h 5m longer, but you will save $35

Cheapest bus trips Saturday

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Economy
    $36
  • Itabus
    14h 30m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $51
  • FlixBus
    14h 10m
    0
    9:35 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $58
  • BlaBlaCar Bus
    14h 45m
    0
    5:30 AM
    Lyon
    Perrache Train Station
    8:15 PM
    Rome
    Tiburtina Bus Station
    0
    BlaBlaCar Bus
    Economy
    $60
  • FlixBus
    15h 30m
    0
    8:45 PM
    Lyon
    Perrache Bus Stop
    12:15 PM
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    $65
  • Did you know that if you travel from Lyon to Rome via Turin, you can save more than $13? You can find the corresponding connections below.
    • Distribusion
      19h 15m
      0
      9:15 AM
      Lyon
      Perrache Bus Stop
      1:45 PM
      Turin
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $22
      • Waiting Time 4h 45m
    • Bookaway
      10h 0m
      0
      6:30 PM
      Turin
      Central Bus Station
      4:30 AM
      Rome
      Tiburtina Bus Station
      0
      Bookaway
      Economy
      $1
    Travel time is 5h 5m longer, but you will save $13

Cheapest bus trips Sunday

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $51
  • FlixBus
    14h 10m
    0
    9:35 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $55
  • FlixBus
    14h 50m
    0
    1:15 AM
    Lyon
    Perrache Bus Stop
    4:05 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $77
  • FlixBus
    15h 30m
    0
    8:45 PM
    Lyon
    Perrache Bus Stop
    12:15 PM
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    $80
  • Itabus
    15h 30m
    0
    3:30 PM
    Lyon
    Perrache Bus Stop
    7:00 AM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $91
  • Did you know that if you travel from Lyon to Rome via Turin, you can save more than $28? You can find the corresponding connections below.
    • Distribusion
      19h 15m
      0
      9:15 AM
      Lyon
      Perrache Bus Stop
      1:45 PM
      Turin
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $22
      • Waiting Time 4h 45m
    • Bookaway
      10h 0m
      0
      6:30 PM
      Turin
      Central Bus Station
      4:30 AM
      Rome
      Tiburtina Bus Station
      0
      Bookaway
      Economy
      $1
    Travel time is 5h 5m longer, but you will save $28

Cheapest bus trips Monday

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $40
  • FlixBus
    14h 10m
    0
    9:35 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $50
  • Itabus
    15h 30m
    0
    3:30 PM
    Lyon
    Perrache Bus Stop
    7:00 AM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $51
  • FlixBus
    15h 30m
    0
    8:45 PM
    Lyon
    Perrache Bus Stop
    12:15 PM
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    $61
  • FlixBus
    14h 50m
    0
    1:15 AM
    Lyon
    Perrache Bus Stop
    4:05 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $96
  • Did you know that if you travel from Lyon to Rome via Turin, you can save more than $17? You can find the corresponding connections below.
    • Distribusion
      19h 15m
      0
      9:15 AM
      Lyon
      Perrache Bus Stop
      1:45 PM
      Turin
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $22
      • Waiting Time 4h 45m
    • Bookaway
      10h 0m
      0
      6:30 PM
      Turin
      Central Bus Station
      4:30 AM
      Rome
      Tiburtina Bus Station
      0
      Bookaway
      Economy
      $1
    Travel time is 5h 5m longer, but you will save $17

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    14h 10m
    0
    9:35 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $46
  • Itabus
    14h 30m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $53
  • Itabus
    15h 30m
    0
    3:30 PM
    Lyon
    Perrache Bus Stop
    7:00 AM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $53
  • FlixBus
    16h 5m
    0
    2:55 PM
    Lyon
    Perrache Bus Stop
    7:00 AM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $80
  • FlixBus
    14h 40m
    0
    3:25 AM
    Lyon
    Perrache Bus Stop
    6:05 PM
    Rome
    Anagnina Bus Station
    0
    FlixBus
    Economy
    $81
  • Did you know that if you travel from Lyon to Rome via Turin, you can save more than $23? You can find the corresponding connections below.
    • Distribusion
      19h 15m
      0
      9:15 AM
      Lyon
      Perrache Bus Stop
      1:45 PM
      Turin
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $22
      • Waiting Time 4h 45m
    • Bookaway
      10h 0m
      0
      6:30 PM
      Turin
      Central Bus Station
      4:30 AM
      Rome
      Tiburtina Bus Station
      0
      Bookaway
      Economy
      $1
    Travel time is 5h 5m longer, but you will save $23

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Economy
    $35
  • Itabus
    14h 30m
    0
    9:15 AM
    Lyon
    Perrache Bus Stop
    11:45 PM
    Rome
    Tiburtina Bus Station
    0
    Itabus
    Premium Economy
    $40
  • BlaBlaCar Bus
    14h 45m
    0
    5:30 AM
    Lyon
    Perrache Train Station
    8:15 PM
    Rome
    Tiburtina Bus Station
    0
    BlaBlaCar Bus
    Economy
    $60
  • FlixBus
    14h 50m
    0
    1:15 AM
    Lyon
    Perrache Bus Stop
    4:05 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $96
  • FlixBus
    17h 20m
    0
    6:15 AM
    Lyon
    Perrache Bus Stop
    11:35 PM
    Rome
    Tiburtina Bus Station
    0
    FlixBus
    Economy
    $96
  • Did you know that if you travel from Lyon to Rome via Turin, you can save more than $12? You can find the corresponding connections below.
    • Distribusion
      19h 15m
      0
      9:15 AM
      Lyon
      Perrache Bus Stop
      1:45 PM
      Turin
      Central Bus Station
      0
      Distribusion
      Premium Economy
      $22
      • Waiting Time 4h 45m
    • Bookaway
      10h 0m
      0
      6:30 PM
      Turin
      Central Bus Station
      4:30 AM
      Rome
      Tiburtina Bus Station
      0
      Bookaway
      Economy
      $1
    Travel time is 4h 45m longer, but you will save $12

Frequency of bus connections between Lyon and Rome

See here how frequent the connections between Lyon and Rome are, during different times and days of the week.
Thursday is the busiest day, with more than 18 daily buses from Lyon to Rome. Tuesday has instead the fewest connections, with only 10 daily coaches between Lyon and Rome.
The busiest time of the day is the Morning, with 28 buses from Lyon to Rome, while Night sees the fewest connections between Lyon and Rome, with 19 offers.

Facts about the bus from Lyon to Rome

Compare all providers like FlixBus, Itabus and BlaBlaCar Bus that travel 14 times every day by bus from Lyon to Rome in one click! Book your bus ticket from Lyon to Rome starting from $35!

Cheapest Bus $35
Fastest Bus 13h 50m
Earliest Bus 1:15 AM
Latest Bus 6:00 PM
Daily Bus Routes 14 Ø
Distance 465.5 miles
Bus Companies FlixBus, Itabus and BlaBlaCar Bus

Cheapest bus connections from Lyon to Rome

Every day, 14 buses from 3 bus companies leave Lyon for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/22/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/18
Monday 05/19
Tuesday 05/20
Wednesday 05/21
Thursday 05/22
$63
Friday 05/23
$93
Saturday 05/24
$51
Sunday 05/25
$51
Monday 05/26
$40
Tuesday 05/27
$53
Wednesday 05/28
$96
Thursday 05/29
$53
Friday 05/30
$79
Saturday 05/31
$69
Sunday 06/01
$75
Monday 06/02
$80
Tuesday 06/03
$40
Wednesday 06/04
$40
Thursday 06/05
$40
Friday 06/06
$57
Saturday 06/07
$63
Sunday 06/08
$63
Monday 06/09
$40
Tuesday 06/10
$67
Wednesday 06/11
$40
Thursday 06/12
$57
Friday 06/13
$65
Saturday 06/14

The cheapest time to travel from Lyon to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Lyon to Rome, for the next 30 days.
With a price starting from $35, Wednesday is the cheapest day for a bus from Lyon to Rome. Friday instead is the most expensive day with prices starting from $58.
Morning is the cheapest day time for bus tickets from Lyon to Rome, with $35. Evening is the most expensive time of the day with prices starting from $61.

How to save money travelling from Lyon to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lyon to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lyon to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lyon to Rome are also emptier.

All bus stations and stops in Lyon and Rome

In the map below, you can see where to find all bus stations in Lyon and Rome.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Lyon to Rome? Compare all modes of transports from Lyon to Rome.

Service and Comfort on the bus from Lyon to Rome

Want to know which seat classes are available on the buses from Lyon to Rome? Or which bus companies serve the route Lyon to Rome? Below you will find answers to your questions.

FAQs about the Lyon to Rome bus

How much does a Lyon Rome bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $35 and takes 14h 30m to reach Rome. Compare offers to save money!

How much could I save by comparing buses from Lyon to Rome?

This route is offered by 3 companies with a range of ticket prices between $35 and $149. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Rome.

On average, how many connections are available from Lyon to Rome each day?

Every day, the Lyon to Rome bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lyon to Rome take?

The fastest bus from Lyon to Rome is offered by FlixBus and takes 13h 50m. Bus tickets for this connection cost $104. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lyon to Rome?

The earliest bus arriving in Rome from Lyon starts at 1:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lyon to Rome?

The latest bus trip departing from Lyon for Rome starts at 6:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lyon Rome route?

When traveling by bus from Lyon to Rome, passengers can travel with FlixBus, Itabus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lyon and Rome?

You can check all the direct connections between Lyon and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and BlaBlaCar Bus.

What can I take with me on the Lyon to Rome bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lyon Rome bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lyon Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lyon to Rome on your planned travel date.

Available seat classes which are offered on the bus route Lyon to Rome

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Lyon and to Rome

Here’s an overview of the most popular bus routes to Lyon and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Annecy to Lyon Bus Annecy to Lyon
From London to Lyon bus From London to Lyon bus
Bus from Lisbon to Lyon Bus from Lisbon to Lyon
From Nice to Lyon bus From Nice to Lyon bus
Bus Pisa to Rome Bus Pisa to Rome
Buses to Rome from Paris Buses to Rome from Paris
Siena to Rome bus Siena to Rome bus
From Civitavecchia to Rome bus From Civitavecchia to Rome bus
Popular Airport Shuttles to Lyon and to Rome
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