What is the best way to travel from Rome to Madrid?
Looking for a trip? Compare all the available Buses and Flights for the journey to Madrid from Rome. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Madrid from Rome?
You can get to Madrid with just $70 by taking a Flight from Air Europa, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus33h 25m01:05 AMRome Fiumicino AirportRome Fiumicino Airport10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/19/2025 1:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/20/2025 10:30:00 AM. 50 Economy ticket for $271 per person are available. Travel duration is 33h 25m
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FlixBus34h 40m011:50 PMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/21/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 40m
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FlixBus34h 55m011:35 PMRomeAnagnina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/19/2025 11:35:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/21/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 55m
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FlixBus36h 0m010:30 PMRome Fiumicino AirportRome Fiumicino Airport10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/19/2025 10:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/21/2025 10:30:00 AM. 50 Economy ticket for $310 per person are available. Travel duration is 36h 0m
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FlixBus32h 10m01:30 AMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 1:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/20/2025 9:40:00 AM. 50 Economy ticket for $330 per person are available. Travel duration is 32h 10m
Cheapest Buses Friday
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Air Europa2h 35m06:25 PMRome Fiumicino AirportRome Fiumicino Airport9:00 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Air Europa goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 6:25:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/20/2025 9:00:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 2h 35m
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LC Perú2h 40m06:00 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 6:00:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/20/2025 8:40:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 2h 40m
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Skyscanner2h 35m04:35 PMRome Fiumicino AirportRome Fiumicino Airport7:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 4:35:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/20/2025 7:10:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 2h 35m
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Iberia2h 35m012:00 PMRome Fiumicino AirportRome Fiumicino Airport2:35 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 12:00:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/20/2025 2:35:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 2h 35m
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Aeronova2h 35m010:30 AMRome Fiumicino AirportRome Fiumicino Airport1:05 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Aeronova goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 10:30:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/20/2025 1:05:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 2h 35m
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FlixBus35h 20m011:10 PMRome Ciampino AirportRome Ciampino Airport10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/20/2025 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/22/2025 10:30:00 AM. 50 Economy ticket for $260 per person are available. Travel duration is 35h 20m
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FlixBus32h 50m01:40 AMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 1:40:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/21/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 32h 50m
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FlixBus34h 40m011:50 PMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/22/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 40m
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FlixBus34h 55m011:35 PMRomeAnagnina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/20/2025 11:35:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/22/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 55m
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FlixBus35h 45m09:55 PMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 9:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/22/2025 9:40:00 AM. 50 Economy ticket for $304 per person are available. Travel duration is 35h 45m
Cheapest Flights Saturday
Cheapest Buses Saturday
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FlixBus34h 40m011:50 PMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/23/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 40m
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FlixBus34h 55m011:35 PMRomeAnagnina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 11:35:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/23/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 55m
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FlixBus32h 50m01:40 AMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 1:40:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/22/2025 10:30:00 AM. 50 Economy ticket for $298 per person are available. Travel duration is 32h 50m
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FlixBus39h 25m06:15 PMRomeAnagnina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 6:15:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/23/2025 9:40:00 AM. 50 Economy ticket for $347 per person are available. Travel duration is 39h 25m
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FlixBus35h 45m09:55 PMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 9:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/23/2025 9:40:00 AM. 50 Economy ticket for $350 per person are available. Travel duration is 35h 45m
Cheapest Buses Sunday
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FlixBus39h 15m05:25 PMRomeAnagnina Bus Station8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 5:25:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 8:40:00 AM. 50 Economy ticket for $227 per person are available. Travel duration is 39h 15m
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FlixBus34h 45m09:55 PMRomeTiburtina Bus Station8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 9:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 8:40:00 AM. 50 Economy ticket for $231 per person are available. Travel duration is 34h 45m
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FlixBus40h 0m06:30 PMRomeAnagnina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 6:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 10:30:00 AM. 50 Economy ticket for $232 per person are available. Travel duration is 40h 0m
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FlixBus39h 25m06:15 PMRomeAnagnina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 6:15:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 9:40:00 AM. 50 Economy ticket for $238 per person are available. Travel duration is 39h 25m
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FlixBus43h 0m03:30 PMRome Ciampino AirportRome Ciampino Airport10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/22/2025 3:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 10:30:00 AM. 50 Economy ticket for $240 per person are available. Travel duration is 43h 0m
Cheapest Buses Monday
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FlixBus34h 40m011:50 PMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/25/2025 10:30:00 AM. 50 Economy ticket for $274 per person are available. Travel duration is 34h 40m
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FlixBus35h 45m09:55 PMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 9:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/25/2025 9:40:00 AM. 50 Economy ticket for $287 per person are available. Travel duration is 35h 45m
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FlixBus39h 25m06:15 PMRomeAnagnina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/23/2025 6:15:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/25/2025 9:40:00 AM. 50 Economy ticket for $292 per person are available. Travel duration is 39h 25m
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FlixBus37h 5m07:35 PMRomeTiburtina Bus Station8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 7:35:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/25/2025 8:40:00 AM. 50 Economy ticket for $315 per person are available. Travel duration is 37h 5m
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FlixBus32h 10m01:30 AMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 1:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 9:40:00 AM. 50 Economy ticket for $317 per person are available. Travel duration is 32h 10m
Cheapest Buses Tuesday
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FlixBus32h 10m01:30 AMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 1:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/25/2025 9:40:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 32h 10m
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FlixBus44h 0m01:05 PMRomeAnagnina Bus Station9:05 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 1:05:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/26/2025 9:05:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 44h 0m
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FlixBus34h 55m011:35 PMRomeAnagnina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 11:35:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/26/2025 10:30:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 34h 55m
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FlixBus34h 40m011:50 PMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/26/2025 10:30:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 34h 40m
Cheapest Buses Wednesday
What are the fastest trips from Rome to Madrid?
You can get to Madrid from Rome in just 2h 35m with a Flight from Air Europa. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus32h 10m01:30 AMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 1:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/20/2025 9:40:00 AM. 50 Economy ticket for $330 per person are available. Travel duration is 32h 10m
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FlixBus33h 25m01:05 AMRome Fiumicino AirportRome Fiumicino Airport10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/19/2025 1:05:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/20/2025 10:30:00 AM. 50 Economy ticket for $271 per person are available. Travel duration is 33h 25m
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FlixBus34h 40m011:50 PMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/19/2025 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/21/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 40m
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FlixBus34h 55m011:35 PMRomeAnagnina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/19/2025 11:35:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/21/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 55m
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FlixBus36h 0m010:30 PMRome Fiumicino AirportRome Fiumicino Airport10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/19/2025 10:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/21/2025 10:30:00 AM. 50 Economy ticket for $310 per person are available. Travel duration is 36h 0m
Fastest Buses Friday
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Air Europa2h 35m06:25 PMRome Fiumicino AirportRome Fiumicino Airport9:00 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Air Europa goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 6:25:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/20/2025 9:00:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 2h 35m
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Skyscanner2h 35m04:35 PMRome Fiumicino AirportRome Fiumicino Airport7:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 4:35:00 PM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/20/2025 7:10:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 2h 35m
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Iberia2h 35m012:00 PMRome Fiumicino AirportRome Fiumicino Airport2:35 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 12:00:00 PM to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/20/2025 2:35:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 2h 35m
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Aeronova2h 35m010:30 AMRome Fiumicino AirportRome Fiumicino Airport1:05 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Aeronova goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 10:30:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/20/2025 1:05:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 2h 35m
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LC Perú2h 40m06:00 AMRome Fiumicino AirportRome Fiumicino Airport8:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 12/20/2025 6:00:00 AM to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 12/20/2025 8:40:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 2h 40m
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FlixBus32h 50m01:40 AMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 1:40:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/21/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 32h 50m
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FlixBus34h 40m011:50 PMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/22/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 40m
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FlixBus34h 55m011:35 PMRomeAnagnina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/20/2025 11:35:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/22/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 55m
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FlixBus35h 20m011:10 PMRome Ciampino AirportRome Ciampino Airport10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/20/2025 11:10:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/22/2025 10:30:00 AM. 50 Economy ticket for $260 per person are available. Travel duration is 35h 20m
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FlixBus35h 45m09:55 PMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/20/2025 9:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/22/2025 9:40:00 AM. 50 Economy ticket for $304 per person are available. Travel duration is 35h 45m
Fastest Flights Saturday
Fastest Buses Saturday
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FlixBus32h 50m01:40 AMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 1:40:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/22/2025 10:30:00 AM. 50 Economy ticket for $298 per person are available. Travel duration is 32h 50m
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FlixBus34h 40m011:50 PMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/23/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 40m
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FlixBus34h 55m011:35 PMRomeAnagnina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 11:35:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/23/2025 10:30:00 AM. 50 Economy ticket for $290 per person are available. Travel duration is 34h 55m
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FlixBus35h 45m09:55 PMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/21/2025 9:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/23/2025 9:40:00 AM. 50 Economy ticket for $350 per person are available. Travel duration is 35h 45m
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FlixBus39h 25m06:15 PMRomeAnagnina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/21/2025 6:15:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/23/2025 9:40:00 AM. 50 Economy ticket for $347 per person are available. Travel duration is 39h 25m
Fastest Buses Sunday
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FlixBus34h 45m09:55 PMRomeTiburtina Bus Station8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/22/2025 9:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 8:40:00 AM. 50 Economy ticket for $231 per person are available. Travel duration is 34h 45m
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FlixBus39h 15m05:25 PMRomeAnagnina Bus Station8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 5:25:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 8:40:00 AM. 50 Economy ticket for $227 per person are available. Travel duration is 39h 15m
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FlixBus39h 25m06:15 PMRomeAnagnina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 6:15:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 9:40:00 AM. 50 Economy ticket for $238 per person are available. Travel duration is 39h 25m
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FlixBus40h 0m06:30 PMRomeAnagnina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/22/2025 6:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 10:30:00 AM. 50 Economy ticket for $232 per person are available. Travel duration is 40h 0m
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FlixBus43h 0m03:30 PMRome Ciampino AirportRome Ciampino Airport10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 12/22/2025 3:30:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 10:30:00 AM. 50 Economy ticket for $240 per person are available. Travel duration is 43h 0m
Fastest Buses Monday
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FlixBus32h 10m01:30 AMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 1:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/24/2025 9:40:00 AM. 50 Economy ticket for $317 per person are available. Travel duration is 32h 10m
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FlixBus34h 40m011:50 PMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/25/2025 10:30:00 AM. 50 Economy ticket for $274 per person are available. Travel duration is 34h 40m
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FlixBus35h 45m09:55 PMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 9:55:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/25/2025 9:40:00 AM. 50 Economy ticket for $287 per person are available. Travel duration is 35h 45m
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FlixBus37h 5m07:35 PMRomeTiburtina Bus Station8:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/23/2025 7:35:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/25/2025 8:40:00 AM. 50 Economy ticket for $315 per person are available. Travel duration is 37h 5m
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FlixBus39h 25m06:15 PMRomeAnagnina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/23/2025 6:15:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/25/2025 9:40:00 AM. 50 Economy ticket for $292 per person are available. Travel duration is 39h 25m
Fastest Buses Tuesday
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FlixBus32h 10m01:30 AMRomeTiburtina Bus Station9:40 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 1:30:00 AM to Sur Bus Station, Madrid (Spain) arriving at 12/25/2025 9:40:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 32h 10m
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FlixBus34h 40m011:50 PMRomeTiburtina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 11:50:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/26/2025 10:30:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 34h 40m
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FlixBus34h 55m011:35 PMRomeAnagnina Bus Station10:30 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 11:35:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/26/2025 10:30:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 34h 55m
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FlixBus44h 0m01:05 PMRomeAnagnina Bus Station9:05 AMMadridSur Bus Station0EconomyA Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 12/24/2025 1:05:00 PM to Sur Bus Station, Madrid (Spain) arriving at 12/26/2025 9:05:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 44h 0m
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Here you will find all operators and timetables for a
Bus from Rome to Madrid
What are the most popular stations in Rome and Madrid?
In Rome, you will usually depart from Termini Bus Station, Termini Central Station or Ostiense Train Station, while in Madrid you will be arriving at Atocha Train Station, Chamartin Train Station or Sur Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Madrid from Rome? With 5 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Madrid, you can pay as low as $70 with a Flight from Air Europa.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Air Europa: you will get to Madrid in just 2h 35m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Madrid are FlixBus, Air Europa and LC Perú, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Madrid is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Delicias, and look at flights from Rome Ciampino Airport, and landing at Adolfo Suárez Madrid-Barajas Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Madrid?
The most popular companies between Rome and Madrid, are FlixBus, Air Europa and LC Perú. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: Air Europa, LC Perú, Skyscanner and 2 more.
All you need to know when you travel from Rome to Madrid
Check all information on comfort and services on all modes of transports from Rome to Madrid. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Madrid
How can I reach Madrid from Rome?
Every day, there are on average 5 connections between Bus and Flight, with which you can get to Madrid from Rome.
How far is Madrid from Rome?
The distance between Rome and Madrid is 848.0 miles.
What is the most ecofriendly mode of transport between Rome and Madrid?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 37 kgs of CO2, a train 48 kgs, a car 232 kgs, and a flight 336 kgs.
What is the cheapest mode of transport from Rome to Madrid?
You can get to Madrid with just $70 by taking a Flight from Air Europa.
What is the fastest way to get from Rome to Madrid?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Madrid in just 2h 35m with a Flight from Air Europa.
More routes to Rome and to Madrid
Looking for more options? Here you can see the most popular routes to Rome and to Madrid. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitanova to Rome
- Foggia to Rome
- Genoa to Rome
- Grottaminarda to Rome
- L'Aquila to Rome
- Lamezia Terme to Rome
- Lecce to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Palermo to Rome
- Perugia to Rome
- Pescara to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Venice to Rome
- Trips to Madrid
- A Coruña to Madrid
- Algeciras to Madrid
- Alicante to Madrid
- Almería to Madrid
- Bilbao to Madrid
- Cordoba to Madrid
- Jaén to Madrid
- Jerez de la Frontera to Madrid
- Mérida to Madrid
- Ourense to Madrid
- Pamplona to Madrid
- Pontevedra to Madrid
- Salamanca (ES) to Madrid
- San Pedro del Pinatar to Madrid
- Santander to Madrid
- Santiago de Compostela to Madrid
- Seville to Madrid
- Talavera de la Reina to Madrid
- Toulouse to Madrid
- Tours to Madrid
- Valladolid to Madrid
- Valmojado to Madrid
- Vitoria-Gasteiz to Madrid
- Zaragoza to Madrid

