How to get from San Antonio, TX to St. Louis, MO

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What is the best way to travel from San Antonio, TX to St. Louis, MO?

Looking for a trip? Compare all the available Flights and Buses for the journey to St. Louis, MO from San Antonio, TX. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 5 available companies to find your perfect trip!
Flight is the cheapest and fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
21h 15m
$109
$119
10
Flight
4h 37m
$95
$272
55

What is the cheapest way to reach St. Louis, MO from San Antonio, TX?

You can get to St. Louis, MO with just $95 by taking a Flight from Frontier Airlines, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Tuesday
from $95
Wednesday
from $95
Thursday
from $111
Friday
from $118
Saturday
from $113
Sunday
from $120
Monday
from $109

    Cheapest Flights Tuesday

  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $95
  • Frontier Airlines
    21h 7m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    6:06 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $95
  • United Airlines
    5h 31m
    0
    6:40 AM
    San Antonio Airport
    San Antonio Airport
    12:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • United Airlines
    8h 1m
    0
    1:20 PM
    San Antonio Airport
    San Antonio Airport
    9:21 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • Skyscanner
    5h 59m
    0
    11:43 AM
    San Antonio Airport
    San Antonio Airport
    5:42 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $428
  • Cheapest Buses Tuesday

  • FlixBus
    24h 50m
    0
    9:55 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $120
  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $121
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $121

    Cheapest Flights Wednesday

  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $95
  • Frontier Airlines
    23h 12m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    8:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $95
  • United Airlines
    5h 31m
    0
    6:40 AM
    San Antonio Airport
    San Antonio Airport
    12:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • United Airlines
    5h 59m
    0
    5:30 PM
    San Antonio Airport
    San Antonio Airport
    11:29 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • Frontier Airlines
    35h 53m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:47 AM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Frontier Airlines
    Economy
    from $195
  • Skyscanner
    5h 59m
    0
    11:43 AM
    San Antonio Airport
    San Antonio Airport
    5:42 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $217
  • Cheapest Buses Wednesday

  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $123
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $124
  • Valley Transit
    25h 45m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $124

    Cheapest Buses Thursday

  • FlixBus
    23h 40m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $111
  • FlixBus
    23h 25m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $111
  • Greyhound US
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $111
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $111
  • Valley Transit
    25h 45m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $113
  • Cheapest Flights Thursday

  • Frontier Airlines
    23h 12m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    8:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $140
  • United Airlines
    5h 31m
    0
    6:40 AM
    San Antonio Airport
    San Antonio Airport
    12:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $195
  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $204
  • Frontier Airlines
    35h 23m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:17 AM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Frontier Airlines
    Economy
    from $233
  • Breeze Airways
    21h 52m
    0
    9:55 AM
    San Antonio Airport
    San Antonio Airport
    7:47 AM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Breeze Airways
    Economy
    from $234
  • Sun Country Airlines
    26h 20m
    0
    6:25 PM
    San Antonio Airport
    San Antonio Airport
    8:45 PM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Sun Country Airlines
    Economy
    from $361

    Cheapest Buses Friday

  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $118
  • FlixBus
    23h 40m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $119
  • FlixBus
    24h 50m
    0
    9:55 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $119
  • Greyhound US
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $119
  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $138
  • Cheapest Flights Friday

  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $120
  • Frontier Airlines
    20h 35m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    5:34 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $204
  • United Airlines
    5h 31m
    0
    6:40 AM
    San Antonio Airport
    San Antonio Airport
    12:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $239
  • United Airlines
    8h 1m
    0
    1:20 PM
    San Antonio Airport
    San Antonio Airport
    9:21 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $239
  • Breeze Airways
    22h 2m
    0
    11:30 AM
    San Antonio Airport
    San Antonio Airport
    9:32 AM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Breeze Airways
    Economy
    from $263
  • Frontier Airlines
    41h 27m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    1:21 PM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Frontier Airlines
    Economy
    from $322

    Cheapest Flights Saturday

  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $113
  • United Airlines
    4h 37m
    0
    5:30 AM
    San Antonio Airport
    San Antonio Airport
    10:07 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • United Airlines
    5h 31m
    0
    6:40 AM
    San Antonio Airport
    San Antonio Airport
    12:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • Frontier Airlines
    23h 12m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    8:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $204
  • Frontier Airlines
    35h 53m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:47 AM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Frontier Airlines
    Economy
    from $256
  • Frontier Airlines
    23h 52m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    8:51 PM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Frontier Airlines
    Economy
    from $267
  • Cheapest Buses Saturday

  • Greyhound US
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $123
  • FlixBus
    23h 40m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $124
  • FlixBus
    23h 25m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $124
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $124
  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $128

    Cheapest Buses Sunday

  • FlixBus
    23h 40m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $120
  • FlixBus
    24h 50m
    0
    9:55 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $120
  • Greyhound US
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $121
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $123
  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $125
  • Cheapest Flights Sunday

  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $247
  • United Airlines
    4h 37m
    0
    5:30 AM
    San Antonio Airport
    San Antonio Airport
    10:07 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $283
  • United Airlines
    7h 12m
    0
    5:30 AM
    San Antonio Airport
    San Antonio Airport
    12:42 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $283
  • Frontier Airlines
    23h 12m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    8:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $288
  • Alaska Airlines
    24h 48m
    0
    5:57 PM
    San Antonio Airport
    San Antonio Airport
    6:45 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Alaska Airlines
    Economy
    from $582

    Cheapest Buses Monday

  • FlixBus
    23h 40m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $109
  • FlixBus
    24h 50m
    0
    9:55 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $109
  • Greyhound US
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $110
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $110
  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $111
  • Cheapest Flights Monday

  • United Airlines
    5h 59m
    0
    5:30 PM
    San Antonio Airport
    San Antonio Airport
    11:29 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $185
  • United Airlines
    7h 22m
    0
    4:35 PM
    San Antonio Airport
    San Antonio Airport
    11:57 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $193
  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $198
  • Frontier Airlines
    19h 19m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    3:13 PM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Frontier Airlines
    Economy
    from $233
  • Frontier Airlines
    20h 6m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    5:05 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $239
  • Alaska Airlines
    29h 57m
    0
    5:57 PM
    San Antonio Airport
    San Antonio Airport
    11:54 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Alaska Airlines
    Economy
    from $445

What are the fastest trips from San Antonio, TX to St. Louis, MO?

You can get to St. Louis, MO from San Antonio, TX in just 4h 37m with a Flight from United Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Tuesday
from 5h 31m
Wednesday
from 5h 31m
Thursday
from 5h 31m
Friday
from 5h 31m
Saturday
from 4h 37m
Sunday
from 4h 37m
Monday
from 5h 59m

    Fastest Flights Tuesday

  • United Airlines
    5h 31m
    0
    6:40 AM
    San Antonio Airport
    San Antonio Airport
    12:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • Skyscanner
    5h 59m
    0
    11:43 AM
    San Antonio Airport
    San Antonio Airport
    5:42 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $428
  • United Airlines
    8h 1m
    0
    1:20 PM
    San Antonio Airport
    San Antonio Airport
    9:21 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • Frontier Airlines
    21h 7m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    6:06 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $95
  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $95
  • Fastest Buses Tuesday

  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $121
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $121
  • FlixBus
    24h 50m
    0
    9:55 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $120

    Fastest Flights Wednesday

  • United Airlines
    5h 31m
    0
    6:40 AM
    San Antonio Airport
    San Antonio Airport
    12:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • United Airlines
    5h 59m
    0
    5:30 PM
    San Antonio Airport
    San Antonio Airport
    11:29 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • Skyscanner
    5h 59m
    0
    11:43 AM
    San Antonio Airport
    San Antonio Airport
    5:42 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $217
  • Frontier Airlines
    17h 27m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    1:21 PM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Frontier Airlines
    Economy
    from $226
  • Frontier Airlines
    23h 12m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    8:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $95
  • Volaris
    23h 19m
    0
    9:32 PM
    San Antonio Airport
    San Antonio Airport
    8:51 PM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Volaris
    Economy
    from $539
  • Fastest Buses Wednesday

  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $123
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $124
  • Valley Transit
    25h 45m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $124

    Fastest Flights Thursday

  • United Airlines
    5h 31m
    0
    6:40 AM
    San Antonio Airport
    San Antonio Airport
    12:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $195
  • Skyscanner
    5h 59m
    0
    11:43 AM
    San Antonio Airport
    San Antonio Airport
    5:42 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $430
  • Frontier Airlines
    18h 27m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    2:21 PM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Frontier Airlines
    Economy
    from $403
  • Breeze Airways
    21h 52m
    0
    9:55 AM
    San Antonio Airport
    San Antonio Airport
    7:47 AM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Breeze Airways
    Economy
    from $234
  • Frontier Airlines
    23h 12m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    8:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $140
  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $204
  • Fastest Buses Thursday

  • Greyhound US
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $111
  • FlixBus
    23h 25m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $111
  • FlixBus
    23h 40m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $111
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $111
  • Valley Transit
    25h 45m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $113

    Fastest Flights Friday

  • United Airlines
    5h 31m
    0
    6:40 AM
    San Antonio Airport
    San Antonio Airport
    12:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $239
  • United Airlines
    8h 1m
    0
    1:20 PM
    San Antonio Airport
    San Antonio Airport
    9:21 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $239
  • Alaska Airlines
    11h 45m
    0
    7:00 AM
    San Antonio Airport
    San Antonio Airport
    6:45 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Alaska Airlines
    Economy
    from $483
  • Frontier Airlines
    20h 35m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    5:34 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $204
  • Breeze Airways
    22h 2m
    0
    11:30 AM
    San Antonio Airport
    San Antonio Airport
    9:32 AM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Breeze Airways
    Economy
    from $263
  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $120
  • Fastest Buses Friday

  • Greyhound US
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $119
  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $138
  • FlixBus
    23h 40m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $119
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $118
  • FlixBus
    24h 50m
    0
    9:55 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $119

    Fastest Flights Saturday

  • United Airlines
    4h 37m
    0
    5:30 AM
    San Antonio Airport
    San Antonio Airport
    10:07 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • United Airlines
    5h 31m
    0
    6:40 AM
    San Antonio Airport
    San Antonio Airport
    12:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $154
  • Skyscanner
    6h 35m
    0
    2:15 PM
    San Antonio Airport
    San Antonio Airport
    8:50 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $331
  • Frontier Airlines
    23h 12m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    8:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $204
  • Volaris
    23h 19m
    0
    9:32 PM
    San Antonio Airport
    San Antonio Airport
    8:51 PM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Volaris
    Economy
    from $544
  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $113
  • Fastest Buses Saturday

  • Greyhound US
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $123
  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $128
  • FlixBus
    23h 25m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $124
  • FlixBus
    23h 40m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $124
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $124

    Fastest Flights Sunday

  • United Airlines
    4h 37m
    0
    5:30 AM
    San Antonio Airport
    San Antonio Airport
    10:07 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $283
  • United Airlines
    7h 12m
    0
    5:30 AM
    San Antonio Airport
    San Antonio Airport
    12:42 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $283
  • Frontier Airlines
    23h 12m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    8:11 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $288
  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $247
  • Alaska Airlines
    24h 48m
    0
    5:57 PM
    San Antonio Airport
    San Antonio Airport
    6:45 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Alaska Airlines
    Economy
    from $582
  • Fastest Buses Sunday

  • Greyhound US
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $121
  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $125
  • FlixBus
    23h 40m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $120
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $123
  • FlixBus
    24h 50m
    0
    9:55 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $120

    Fastest Flights Monday

  • United Airlines
    5h 59m
    0
    5:30 PM
    San Antonio Airport
    San Antonio Airport
    11:29 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $185
  • United Airlines
    7h 22m
    0
    4:35 PM
    San Antonio Airport
    San Antonio Airport
    11:57 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $193
  • Frontier Airlines
    19h 19m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    3:13 PM
    MidAmerica St. Louis Airport
    MidAmerica St. Louis Airport
    0
    Frontier Airlines
    Economy
    from $233
  • Frontier Airlines
    20h 6m
    0
    8:59 PM
    San Antonio Airport
    San Antonio Airport
    5:05 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $239
  • Frontier Airlines
    23h 29m
    0
    7:54 PM
    San Antonio Airport
    San Antonio Airport
    7:23 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $198
  • Alaska Airlines
    29h 57m
    0
    5:57 PM
    San Antonio Airport
    San Antonio Airport
    11:54 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Alaska Airlines
    Economy
    from $445
  • Fastest Buses Monday

  • Greyhound US
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $110
  • Greyhound Lines Mexico
    21h 15m
    0
    1:30 AM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $111
  • FlixBus
    23h 40m
    0
    7:30 AM
    San Antonio, TX
    Bus Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $109
  • Greyhound US
    24h 20m
    0
    12:35 PM
    San Antonio, TX
    Bus Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $110
  • FlixBus
    24h 50m
    0
    9:55 PM
    San Antonio, TX
    Bus Station
    10:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $109
Here you will find all operators and timetables for a Bus from San Antonio, TX to St. Louis, MO

What are the most popular stations in San Antonio, TX and St. Louis, MO?

In San Antonio, TX, you will usually depart from Tornado Bus Company, Bus Station or W. Southcross & Buffalo Bus Stop, while in St. Louis, MO you will be arriving at Skinker Boulevard, Lindbergh @ Hackberry NB Bus Stop or Gateway Station, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to St. Louis, MO from San Antonio, TX? With 12 connections between 5 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between San Antonio, TX and St. Louis, MO, you can pay as low as $95 with a Flight from Frontier Airlines.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to St. Louis, MO in just 4h 37m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting San Antonio, TX and St. Louis, MO are Frontier Airlines, United Airlines and FlixBus, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in San Antonio, TX and St. Louis, MO is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Olmos Park, TX or to Sauget, IL, and look at flights from San Antonio Airport, and landing at St. Louis Lambert Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from San Antonio, TX to St. Louis, MO?

The most popular companies between San Antonio, TX and St. Louis, MO, are Frontier Airlines, United Airlines and FlixBus. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus, Greyhound US, Greyhound Lines Mexico and 1 more.

Airlines: Frontier Airlines, United Airlines, Volaris and 4 more.

All you need to know when you travel from San Antonio, TX to St. Louis, MO

Check all information on comfort and services on all modes of transports from San Antonio, TX to St. Louis, MO. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from San Antonio, TX to St. Louis, MO

How can I reach St. Louis, MO from San Antonio, TX?

Every day, there are on average 12 connections between Flight and Bus, with which you can get to St. Louis, MO from San Antonio, TX.

How far is St. Louis, MO from San Antonio, TX?

The distance between San Antonio, TX and St. Louis, MO is 792.3 miles.

What is the most ecofriendly mode of transport between San Antonio, TX and St. Louis, MO?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 34 kgs of CO2, a train 45 kgs, a car 217 kgs, and a flight 314 kgs.

What is the cheapest mode of transport from San Antonio, TX to St. Louis, MO?

You can get to St. Louis, MO with just $95 by taking a Flight from Frontier Airlines.

What is the fastest way to get from San Antonio, TX to St. Louis, MO?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to St. Louis, MO in just 4h 37m with a Flight from United Airlines.

More routes to San Antonio, TX and to St. Louis, MO

Looking for more options? Here you can see the most popular routes to San Antonio, TX and to St. Louis, MO. Simply click on a connection, and you’ll find all the details about the route!

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