Bus Tupelo, MS to Houston: Compare prices and save money

Compare all timetables for the bus from Tupelo, MS to Houston

Here is a selection of the cheapest bus trips from the schedule from Tupelo, MS to Houston from various bus operators like Greyhound US for the next days.

today

tomorrow

$123

Tuesday

$131

Wednesday

Thursday

$136

Friday

$143

Saturday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 55m	5:35 AM	Tupelo, MS	Bus Stop	11:30 PM	Houston	Harrisburg Blvd Station	Economy	$123	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/15/2025 5:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/15/2025 11:30:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 17h 55m
Greyhound US	30h 0m	11:15 PM	Tupelo, MS	Bus Stop	5:15 AM	Houston	Downtown Houston	Economy	$123	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/15/2025 11:15:00 PM to Downtown Houston, Houston (USA) arriving at 12/17/2025 5:15:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 30h 0m
Greyhound US	19h 30m	9:35 PM	Tupelo, MS	Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$124	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/15/2025 9:35:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 12/16/2025 5:05:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 19h 30m
Greyhound US	23h 40m	5:35 AM	Tupelo, MS	Bus Stop	5:15 AM	Houston	Downtown Houston	Economy	$124	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/15/2025 5:35:00 AM to Downtown Houston, Houston (USA) arriving at 12/16/2025 5:15:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 23h 40m
Greyhound US	20h 15m	10:55 AM	Tupelo, MS	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$125	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/15/2025 10:55:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/16/2025 7:10:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 20h 15m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 55m	5:35 AM	Tupelo, MS	Bus Stop	11:30 PM	Houston	Harrisburg Blvd Station	Economy	$131	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/16/2025 5:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/16/2025 11:30:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 17h 55m
Greyhound US	20h 15m	10:55 AM	Tupelo, MS	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$131	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/16/2025 10:55:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/17/2025 7:10:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 20h 15m
Greyhound US	23h 40m	5:35 AM	Tupelo, MS	Bus Stop	5:15 AM	Houston	Downtown Houston	Economy	$132	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/16/2025 5:35:00 AM to Downtown Houston, Houston (USA) arriving at 12/17/2025 5:15:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 23h 40m
Greyhound US	19h 30m	9:35 PM	Tupelo, MS	Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$133	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/16/2025 9:35:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 12/17/2025 5:05:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 19h 30m
Greyhound US	25h 5m	10:55 AM	Tupelo, MS	Bus Stop	12:00 PM	Houston	Downtown Houston	Economy	$133	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/16/2025 10:55:00 AM to Downtown Houston, Houston (USA) arriving at 12/17/2025 12:00:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 25h 5m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	23h 40m	5:35 AM	Tupelo, MS	Bus Stop	5:15 AM	Houston	Downtown Houston	Economy	$136	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/18/2025 5:35:00 AM to Downtown Houston, Houston (USA) arriving at 12/19/2025 5:15:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 23h 40m
Greyhound US	20h 15m	10:55 AM	Tupelo, MS	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$137	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/18/2025 10:55:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/19/2025 7:10:00 AM. 50 Economy ticket for $137 per person are available. Travel duration is 20h 15m
Greyhound US	19h 30m	9:35 PM	Tupelo, MS	Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$138	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/18/2025 9:35:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 12/19/2025 5:05:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 19h 30m
Greyhound US	30h 0m	11:15 PM	Tupelo, MS	Bus Stop	5:15 AM	Houston	Downtown Houston	Economy	$138	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/18/2025 11:15:00 PM to Downtown Houston, Houston (USA) arriving at 12/20/2025 5:15:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 30h 0m
Greyhound US	23h 35m	11:15 PM	Tupelo, MS	Bus Stop	10:50 PM	Houston	Harrisburg Blvd Station	Economy	$147	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/18/2025 11:15:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 12/19/2025 10:50:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 23h 35m

Did you know that if you travel from Tupelo, MS to Houston via Memphis, you can save more than $17? You can find the corresponding connections below.
- FlixBus
  
  19h 15m
  
  0
  
  9:35 PM
  
  Tupelo, MS
  Bus Stop
  
  11:25 PM
  
  Memphis
  Airways Transit Center
  
  0
  
  Economy
  
  $21
  
  A Bus from FlixBus goes from Bus Stop, Tupelo, MS (USA) at 12/15/2025 9:35:00 PM to Airways Transit Center, Memphis (USA) arriving at 12/15/2025 11:25:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 1h 50m
- Busbud
  
  14h 15m
  
  0
  
  2:35 AM
  
  Memphis
  Airways Transit Center
  
  4:50 PM
  
  Houston
  Uptown/Upper Kirby
  
  0
  
  Economy
  
  $98
  
  A Bus from Busbud goes from Airways Transit Center, Memphis (USA) at 12/16/2025 2:35:00 AM to Uptown/Upper Kirby, Houston (USA) arriving at 12/16/2025 4:50:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 14h 15m
Travel Time is 0h 15m shorter, and you will save $17

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	19h 30m	9:35 PM	Tupelo, MS	Bus Stop	5:05 PM	Houston	Harrisburg Blvd Station	Economy	$143	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/19/2025 9:35:00 PM to Harrisburg Blvd Station, Houston (USA) arriving at 12/20/2025 5:05:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 19h 30m
Greyhound US	23h 40m	5:35 AM	Tupelo, MS	Bus Stop	5:15 AM	Houston	Downtown Houston	Economy	$143	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/19/2025 5:35:00 AM to Downtown Houston, Houston (USA) arriving at 12/20/2025 5:15:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 23h 40m
Greyhound US	17h 55m	5:35 AM	Tupelo, MS	Bus Stop	11:30 PM	Houston	Harrisburg Blvd Station	Economy	$150	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/19/2025 5:35:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/19/2025 11:30:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 17h 55m
Greyhound US	20h 15m	10:55 AM	Tupelo, MS	Bus Stop	7:10 AM	Houston	Harrisburg Blvd Station	Economy	$153	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/19/2025 10:55:00 AM to Harrisburg Blvd Station, Houston (USA) arriving at 12/20/2025 7:10:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 20h 15m
Greyhound US	25h 5m	10:55 AM	Tupelo, MS	Bus Stop	12:00 PM	Houston	Downtown Houston	Economy	$155	A Bus from Greyhound US goes from Bus Stop, Tupelo, MS (USA) at 12/19/2025 10:55:00 AM to Downtown Houston, Houston (USA) arriving at 12/20/2025 12:00:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 25h 5m

Did you know that if you travel from Tupelo, MS to Houston via Memphis, you can save more than $24? You can find the corresponding connections below.
- FlixBus
  
  19h 15m
  
  0
  
  9:35 PM
  
  Tupelo, MS
  Bus Stop
  
  11:25 PM
  
  Memphis
  Airways Transit Center
  
  0
  
  Economy
  
  $21
  
  A Bus from FlixBus goes from Bus Stop, Tupelo, MS (USA) at 12/15/2025 9:35:00 PM to Airways Transit Center, Memphis (USA) arriving at 12/15/2025 11:25:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 1h 50m
- Busbud
  
  14h 15m
  
  0
  
  2:35 AM
  
  Memphis
  Airways Transit Center
  
  4:50 PM
  
  Houston
  Uptown/Upper Kirby
  
  0
  
  Economy
  
  $98
  
  A Bus from Busbud goes from Airways Transit Center, Memphis (USA) at 12/16/2025 2:35:00 AM to Uptown/Upper Kirby, Houston (USA) arriving at 12/16/2025 4:50:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 14h 15m
Travel time is 1h 20m longer, but you will save $24

Best Price Offer: The price for the cheapest bus from Tupelo, MS to Houston is $123 on 12/15/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Tupelo, MS and Houston

See here how frequent the connections between Tupelo, MS and Houston are, during different times and days of the week.

Thursday is the busiest day, with more than 9 daily buses from Tupelo, MS to Houston. Tuesday has instead the fewest connections, with only 6 daily coaches between Tupelo, MS and Houston.

The busiest time of the day is the Evening, with 11 buses from Tupelo, MS to Houston, while Morning sees the fewest connections between Tupelo, MS and Houston, with 10 offers.

Facts about the bus from Tupelo, MS to Houston

Compare all providers like Greyhound US that travel 7 times every day by bus from Tupelo, MS to Houston in one click! Book your bus ticket from Tupelo, MS to Houston starting from $123!

Cheapest Bus	$123
Fastest Bus	17h 55m
Earliest Bus	5:35 AM
Latest Bus	11:15 PM
Daily Bus Routes	7 Ø
Distance	499.6 miles
Bus Companies	Greyhound US

Cheapest bus connections from Tupelo, MS to Houston

Every day, 7 buses from 1 bus companies leave Tupelo, MS for Houston: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/14/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

$123

Tuesday 12/16

$131

Wednesday 12/17

Thursday 12/18

$136

Friday 12/19

$143

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

$141

Wednesday 12/24

Thursday 12/25

Friday 12/26

$123

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Tupelo, MS to Houston

See here on which day and which time of the day you can find the cheapest bus ticket from Tupelo, MS to Houston, for the next 30 days.

With a price starting from $123, Monday is the cheapest day for a bus from Tupelo, MS to Houston. Thursday instead is the most expensive day with prices starting from $136.

Evening is the cheapest day time for bus tickets from Tupelo, MS to Houston, with $123. Morning is the most expensive time of the day with prices starting from $125.

How to save money travelling from Tupelo, MS to Houston

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tupelo, MS to Houston in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tupelo, MS to Houston, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tupelo, MS to Houston are also emptier.

All bus stations and stops in Tupelo, MS and Houston

In the map below, you can see where to find all bus stations in Tupelo, MS and Houston.

Bus Stop

S Eason Blvd 2831

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Uptown/Upper Kirby

Southwest Fwy 2525

Chase Bank

Milam Street 212

Service and Comfort on the bus from Tupelo, MS to Houston

Want to know which seat classes are available on the buses from Tupelo, MS to Houston? Or which bus companies serve the route Tupelo, MS to Houston? Below you will find answers to your questions.

FAQs about the Tupelo, MS to Houston bus

How much does a Tupelo, MS Houston bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $123 and takes 30h 0m to reach Houston. Compare offers to save money!

How much could I save by comparing buses from Tupelo, MS to Houston?

This route is offered by 1 companies with a range of ticket prices between $123 and $232. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Houston.

On average, how many connections are available from Tupelo, MS to Houston each day?

Every day, the Tupelo, MS to Houston bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tupelo, MS to Houston take?

The fastest bus from Tupelo, MS to Houston is offered by Greyhound US and takes 17h 55m. Bus tickets for this connection cost $123. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tupelo, MS to Houston?

The earliest bus arriving in Houston from Tupelo, MS starts at 5:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tupelo, MS to Houston?

The latest bus trip departing from Tupelo, MS for Houston starts at 11:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tupelo, MS Houston route?

When traveling by bus from Tupelo, MS to Houston, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tupelo, MS and Houston?

You can check all the direct connections between Tupelo, MS and Houston by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Tupelo, MS to Houston bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tupelo, MS Houston bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tupelo, MS Houston bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tupelo, MS to Houston on your planned travel date.

Available seat classes which are offered on the bus route Tupelo, MS to Houston

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tupelo, MS and to Houston

Here’s an overview of the most popular bus routes to Tupelo, MS and to Houston. Simply click on the connection of your choice, and you will find all the details about your bus route!