Bus Chicago to Lafayette, LA - Compare all Companies

Compare all timetables for the bus from Chicago to Lafayette, LA

Here is a selection of the cheapest bus trips from the schedule from Chicago to Lafayette, LA from various bus operators like Greyhound US or FlixBus for the next days.

today

$144

tomorrow

$178

Friday

Saturday

Sunday

$198

Monday

Tuesday

$178

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 40m	10:30 PM	Chicago	Downtown Bus Station	9:10 PM	Lafayette, LA	Bus Stop	Economy	$144	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/17/2025 10:30:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/18/2025 9:10:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 22h 40m
Greyhound US	28h 15m	10:50 PM	Chicago	Downtown Bus Station	3:05 AM	Lafayette, LA	Bus Stop	Economy	$144	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/17/2025 10:50:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/19/2025 3:05:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 28h 15m
Greyhound US	27h 55m	11:10 PM	Chicago	Union Station	3:05 AM	Lafayette, LA	Bus Stop	Economy	$144	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/17/2025 11:10:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/19/2025 3:05:00 AM. 50 Economy ticket for $144 per person are available. Travel duration is 27h 55m
FlixBus	30h 0m	7:25 PM	Chicago	95th Red Line Station	1:25 AM	Lafayette, LA	TA Travel Center	Economy	$146	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 12/17/2025 7:25:00 PM to TA Travel Center, Lafayette, LA (USA) arriving at 12/19/2025 1:25:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 30h 0m
FlixBus	25h 45m	7:25 PM	Chicago	95th Red Line Station	9:10 PM	Lafayette, LA	Bus Stop	Economy	$146	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 12/17/2025 7:25:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/18/2025 9:10:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 25h 45m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	33h 5m	11:10 PM	Chicago	Union Station	8:15 AM	Lafayette, LA	TA Travel Center	Economy	$178	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/18/2025 11:10:00 PM to TA Travel Center, Lafayette, LA (USA) arriving at 12/20/2025 8:15:00 AM. 50 Economy ticket for $178 per person are available. Travel duration is 33h 5m
Greyhound US	29h 55m	6:10 AM	Chicago	Downtown Bus Station	12:05 PM	Lafayette, LA	Bus Stop	Economy	$185	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/18/2025 6:10:00 AM to Bus Stop, Lafayette, LA (USA) arriving at 12/19/2025 12:05:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 29h 55m
Greyhound US	28h 15m	10:50 PM	Chicago	Downtown Bus Station	3:05 AM	Lafayette, LA	Bus Stop	Economy	$202	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/18/2025 10:50:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/20/2025 3:05:00 AM. 50 Economy ticket for $202 per person are available. Travel duration is 28h 15m
Greyhound US	27h 55m	11:10 PM	Chicago	Union Station	3:05 AM	Lafayette, LA	Bus Stop	Economy	$202	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/18/2025 11:10:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/20/2025 3:05:00 AM. 50 Economy ticket for $202 per person are available. Travel duration is 27h 55m
Greyhound US	22h 40m	10:30 PM	Chicago	Downtown Bus Station	9:10 PM	Lafayette, LA	Bus Stop	Economy	$209	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/18/2025 10:30:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/19/2025 9:10:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 22h 40m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 30m	9:45 AM	Chicago	Downtown Bus Station	8:15 AM	Lafayette, LA	TA Travel Center	Economy	$198	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/21/2025 9:45:00 AM to TA Travel Center, Lafayette, LA (USA) arriving at 12/22/2025 8:15:00 AM. 50 Economy ticket for $198 per person are available. Travel duration is 22h 30m
FlixBus	23h 20m	9:45 AM	Chicago	Downtown Bus Station	9:05 AM	Lafayette, LA	Bus Stop	Economy	$198	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/21/2025 9:45:00 AM to Bus Stop, Lafayette, LA (USA) arriving at 12/22/2025 9:05:00 AM. 50 Economy ticket for $198 per person are available. Travel duration is 23h 20m
Greyhound US	28h 15m	10:50 PM	Chicago	Downtown Bus Station	3:05 AM	Lafayette, LA	Bus Stop	Economy	$200	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/21/2025 10:50:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/23/2025 3:05:00 AM. 50 Economy ticket for $200 per person are available. Travel duration is 28h 15m
Greyhound US	27h 55m	11:10 PM	Chicago	Union Station	3:05 AM	Lafayette, LA	Bus Stop	Economy	$200	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/21/2025 11:10:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/23/2025 3:05:00 AM. 50 Economy ticket for $200 per person are available. Travel duration is 27h 55m
Greyhound US	33h 5m	11:10 PM	Chicago	Union Station	8:15 AM	Lafayette, LA	TA Travel Center	Economy	$210	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/21/2025 11:10:00 PM to TA Travel Center, Lafayette, LA (USA) arriving at 12/23/2025 8:15:00 AM. 50 Economy ticket for $210 per person are available. Travel duration is 33h 5m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 20m	9:45 AM	Chicago	Downtown Bus Station	9:05 AM	Lafayette, LA	Bus Stop	Economy	$178	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/23/2025 9:45:00 AM to Bus Stop, Lafayette, LA (USA) arriving at 12/24/2025 9:05:00 AM. 50 Economy ticket for $178 per person are available. Travel duration is 23h 20m
FlixBus	22h 30m	9:45 AM	Chicago	Downtown Bus Station	8:15 AM	Lafayette, LA	TA Travel Center	Economy	$179	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/23/2025 9:45:00 AM to TA Travel Center, Lafayette, LA (USA) arriving at 12/24/2025 8:15:00 AM. 50 Economy ticket for $179 per person are available. Travel duration is 22h 30m
Greyhound US	22h 40m	10:30 PM	Chicago	Downtown Bus Station	9:10 PM	Lafayette, LA	Bus Stop	Economy	$181	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/23/2025 10:30:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/24/2025 9:10:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 22h 40m
Greyhound US	28h 15m	10:50 PM	Chicago	Downtown Bus Station	3:05 AM	Lafayette, LA	Bus Stop	Economy	$192	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/23/2025 10:50:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/25/2025 3:05:00 AM. 50 Economy ticket for $192 per person are available. Travel duration is 28h 15m
Greyhound US	27h 55m	11:10 PM	Chicago	Union Station	3:05 AM	Lafayette, LA	Bus Stop	Economy	$192	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/23/2025 11:10:00 PM to Bus Stop, Lafayette, LA (USA) arriving at 12/25/2025 3:05:00 AM. 50 Economy ticket for $192 per person are available. Travel duration is 27h 55m

Best Price Offer: The price for the cheapest bus from Chicago to Lafayette, LA is $138 on 1/5/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and Lafayette, LA

See here how frequent the connections between Chicago and Lafayette, LA are, during different times and days of the week.

Wednesday is the busiest day, with more than 16 daily buses from Chicago to Lafayette, LA. Tuesday has instead the fewest connections, with only 7 daily coaches between Chicago and Lafayette, LA.

The busiest time of the day is the Evening, with 26 buses from Chicago to Lafayette, LA, while Morning sees the fewest connections between Chicago and Lafayette, LA, with 12 offers.

Facts about the bus from Chicago to Lafayette, LA

Compare all providers like Greyhound US and FlixBus that travel 9 times every day by bus from Chicago to Lafayette, LA in one click! Book your bus ticket from Chicago to Lafayette, LA starting from $138!

Cheapest Bus	$138
Fastest Bus	22h 30m
Earliest Bus	6:10 AM
Latest Bus	11:10 PM
Daily Bus Routes	9 Ø
Distance	841.4 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Chicago to Lafayette, LA

Every day, 9 buses from 2 bus companies leave Chicago for Lafayette, LA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/17/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

$144

Thursday 12/18

$178

Friday 12/19

Saturday 12/20

Sunday 12/21

$198

Monday 12/22

Tuesday 12/23

$178

Wednesday 12/24

$193

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

$176

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

$143

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

$138

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Chicago to Lafayette, LA

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to Lafayette, LA, for the next 30 days.

With a price starting from $143, Thursday is the cheapest day for a bus from Chicago to Lafayette, LA. Tuesday instead is the most expensive day with prices starting from $178.

Evening is the cheapest day time for bus tickets from Chicago to Lafayette, LA, with $144. Morning is the most expensive time of the day with prices starting from $145.

How to save money travelling from Chicago to Lafayette, LA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to Lafayette, LA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Lafayette, LA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Lafayette, LA are also emptier.

Beloved bus companies from Chicago to Lafayette, LA

These are the most booked bus companies between Chicago to Lafayette, LA from our users.

Greyhound US from Chicago to Lafayette, LA

Here you will find the key facts about the Greyhound US bus route Chicago to Lafayette, LA:

Cheapest Price	$144
Fastest Bus	22h 40m
Earliest Bus	6:10 AM
Last Bus	11:10 PM
Daily Connections	8 Ø
Found on	12/14/2025

All bus stations and stops in Chicago and Lafayette, LA

In the map below, you can see where to find all bus stations in Chicago and Lafayette, LA.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Bus Stop

Lee Ave 100

TA Travel Center

N University Ave 1701

Cameron Street & Alley Five Bus Stop

Cameron St 2405

Service and Comfort on the bus from Chicago to Lafayette, LA

Want to know which seat classes are available on the buses from Chicago to Lafayette, LA? Or which bus companies serve the route Chicago to Lafayette, LA? Below you will find answers to your questions.

FAQs about the Chicago to Lafayette, LA bus

How much does a Chicago Lafayette, LA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $138 and takes 22h 40m to reach Lafayette, LA. Compare offers to save money!

How much could I save by comparing buses from Chicago to Lafayette, LA?

This route is offered by 2 companies with a range of ticket prices between $138 and $243. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lafayette, LA.

On average, how many connections are available from Chicago to Lafayette, LA each day?

Every day, the Chicago to Lafayette, LA bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to Lafayette, LA take?

The fastest bus from Chicago to Lafayette, LA is offered by FlixBus and takes 22h 30m. Bus tickets for this connection cost $198. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to Lafayette, LA?

The earliest bus arriving in Lafayette, LA from Chicago starts at 6:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to Lafayette, LA?

The latest bus trip departing from Chicago for Lafayette, LA starts at 11:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago Lafayette, LA route?

When traveling by bus from Chicago to Lafayette, LA, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and Lafayette, LA?

You can check all the direct connections between Chicago and Lafayette, LA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to Lafayette, LA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Lafayette, LA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago Lafayette, LA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Lafayette, LA on your planned travel date.

How does CheckMyBus find the best bus deals from Chicago to Lafayette, LA?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Chicago and Lafayette, LA. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Chicago to Lafayette, LA?

Prices and availability for 9 trips between Chicago and Lafayette, LA change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Chicago to Lafayette, LA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to Lafayette, LA

Here’s an overview of the most popular bus routes to Chicago and to Lafayette, LA. Simply click on the connection of your choice, and you will find all the details about your bus route!