Bus Santiago de Queretaro to Chicago: Compare prices and save money

Compare all timetables for the bus from Santiago de Queretaro to Chicago

Here is a selection of the cheapest bus trips from the schedule from Santiago de Queretaro to Chicago from various bus operators like Flix Mexico for the next days.

today

$221

tomorrow

Wednesday

Thursday

Friday

Saturday

$221

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	58h 0m	12:35 PM	Santiago de Queretaro	Centro Comercial Galeria	11:35 PM	Chicago	95th Red Line Station	Economy	$221	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/20/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/22/2026 11:35:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 58h 0m
Flix Mexico	55h 25m	8:55 PM	Santiago de Queretaro	Centro Comercial Galeria	5:20 AM	Chicago	95th Red Line Station	Economy	$222	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/20/2026 8:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/23/2026 5:20:00 AM. 50 Economy ticket for $222 per person are available. Travel duration is 55h 25m
Flix Mexico	50h 50m	1:30 AM	Santiago de Queretaro	Centro Comercial Galeria	5:20 AM	Chicago	95th Red Line Station	Economy	$225	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/20/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 4/22/2026 5:20:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 50h 50m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	53h 25m	10:55 PM	Santiago de Queretaro	Centro Comercial Galeria	5:20 AM	Chicago	95th Red Line Station	Economy	$221	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/25/2026 10:55:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/28/2026 5:20:00 AM. 50 Economy ticket for $221 per person are available. Travel duration is 53h 25m
Flix Mexico	50h 50m	1:30 AM	Santiago de Queretaro	Centro Comercial Galeria	5:20 AM	Chicago	95th Red Line Station	Economy	$223	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/25/2026 1:30:00 AM to 95th Red Line Station, Chicago (USA) arriving at 4/27/2026 5:20:00 AM. 50 Economy ticket for $223 per person are available. Travel duration is 50h 50m
Flix Mexico	58h 0m	12:35 PM	Santiago de Queretaro	Centro Comercial Galeria	11:35 PM	Chicago	95th Red Line Station	Economy	$223	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/25/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 4/27/2026 11:35:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 58h 0m

Did you know that if you travel from Santiago de Queretaro to Chicago via McAllen, TX, you can save more than $53? You can find the corresponding connections below.
- Flix Mexico
  
  73h 50m
  
  0
  
  1:30 AM
  
  Santiago de Queretaro
  Centro Comercial Galeria
  
  10:30 PM
  
  McAllen, TX
  Central Bus Station
  
  0
  
  Economy
  
  $56
  
  A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 4/26/2026 1:30:00 AM to Central Bus Station, McAllen, TX (USA) arriving at 4/26/2026 10:30:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 20h 0m
- Greyhound US
  
  38h 0m
  
  0
  
  2:20 PM
  
  McAllen, TX
  Central Bus Station
  
  4:20 AM
  
  Chicago
  Downtown Bus Station
  
  0
  
  Economy
  
  $112
  
  A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 4/27/2026 2:20:00 PM to Downtown Bus Station, Chicago (USA) arriving at 4/29/2026 4:20:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 38h 0m
Travel time is 22h 0m longer, but you will save $53

Best Price Offer: The price for the cheapest bus from Santiago de Queretaro to Chicago is $129 on 5/8/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Santiago de Queretaro and Chicago

See here how frequent the connections between Santiago de Queretaro and Chicago are, during different times and days of the week.

Monday is the busiest day, with more than 3 daily buses from Santiago de Queretaro to Chicago. Monday has instead the fewest connections, with only 3 daily coaches between Santiago de Queretaro and Chicago.

The busiest time of the day is the Afternoon, with 2 buses from Santiago de Queretaro to Chicago, while Afternoon sees the fewest connections between Santiago de Queretaro and Chicago, with 2 offers.

Facts about the bus from Santiago de Queretaro to Chicago

Compare all providers like Flix Mexico that travel 3 times every day by bus from Santiago de Queretaro to Chicago in one click! Book your bus ticket from Santiago de Queretaro to Chicago starting from $129!

Cheapest Bus	$129
Fastest Bus	51h 50m
Earliest Bus	1:30 AM
Latest Bus	10:55 PM
Daily Bus Routes	3 Ø
Distance	1,648.5 miles
Bus Companies	Flix Mexico

Cheapest bus connections from Santiago de Queretaro to Chicago

Every day, 3 buses from 1 bus companies leave Santiago de Queretaro for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$221

Tuesday 04/21

Wednesday 04/22

Thursday 04/23

Friday 04/24

Saturday 04/25

$160

Sunday 04/26

$143

Monday 04/27

$221

Tuesday 04/28

$221

Wednesday 04/29

$221

Thursday 04/30

$138

Friday 05/01

$134

Saturday 05/02

$169

Sunday 05/03

$142

Monday 05/04

$223

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$129

Saturday 05/09

$144

Sunday 05/10

$220

Monday 05/11

$155

Tuesday 05/12

$221

Wednesday 05/13

$220

Thursday 05/14

Friday 05/15

$133

Saturday 05/16

The cheapest time to travel from Santiago de Queretaro to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago de Queretaro to Chicago, for the next 30 days.

With a price starting from $135, Saturday is the cheapest day for a bus from Santiago de Queretaro to Chicago. Monday instead is the most expensive day with prices starting from $155.

Night is the cheapest day time for bus tickets from Santiago de Queretaro to Chicago, with $129. Afternoon is the most expensive time of the day with prices starting from $221.

How to save money travelling from Santiago de Queretaro to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago de Queretaro to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago de Queretaro to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago de Queretaro to Chicago are also emptier.

All bus stations and stops in Santiago de Queretaro and Chicago

In the map below, you can see where to find all bus stations in Santiago de Queretaro and Chicago.

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

El Colorado

Walmart Juriquilla

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Santiago de Queretaro to Chicago

Want to know which seat classes are available on the buses from Santiago de Queretaro to Chicago? Or which bus companies serve the route Santiago de Queretaro to Chicago? Below you will find answers to your questions.

FAQs about the Santiago de Queretaro to Chicago bus

How much does a Santiago de Queretaro Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $129 and takes 54h 25m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Santiago de Queretaro to Chicago?

This route is offered by 1 companies with a range of ticket prices between $129 and $225. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Santiago de Queretaro to Chicago each day?

Every day, the Santiago de Queretaro to Chicago bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago de Queretaro to Chicago take?

The fastest bus from Santiago de Queretaro to Chicago is offered by Flix Mexico and takes 51h 50m. Bus tickets for this connection cost $225. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago de Queretaro to Chicago?

The earliest bus arriving in Chicago from Santiago de Queretaro starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago de Queretaro to Chicago?

The latest bus trip departing from Santiago de Queretaro for Chicago starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago de Queretaro Chicago route?

When traveling by bus from Santiago de Queretaro to Chicago, passengers can travel with Flix Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago de Queretaro and Chicago?

You can check all the direct connections between Santiago de Queretaro and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Flix Mexico.

What can I take with me on the Santiago de Queretaro to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago de Queretaro Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago de Queretaro Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago de Queretaro to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago de Queretaro to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Santiago de Queretaro and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago de Queretaro to Chicago?

Prices and availability for 3 trips between Santiago de Queretaro and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago de Queretaro to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Santiago de Queretaro and to Chicago

Here’s an overview of the most popular bus routes to Santiago de Queretaro and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!