Bus Santiago de Queretaro to Chicago: Compare prices and save money

Compare all timetables for the bus from Santiago de Queretaro to Chicago

Here is a selection of the cheapest bus trips from the schedule from Santiago de Queretaro to Chicago from various bus operators like Flix Mexico for the next days.

today

$219

tomorrow

$219

Wednesday

Thursday

$219

Friday

Saturday

$219

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	55h 35m	12:35 PM	Santiago de Queretaro	Centro Comercial Galeria	8:10 PM	Chicago	Downtown Bus Station	Economy	$219	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/19/2026 12:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 1/21/2026 8:10:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 55h 35m
Flix Mexico	55h 5m	9:05 PM	Santiago de Queretaro	Centro Comercial Galeria	4:10 AM	Chicago	Downtown Bus Station	Economy	$219	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/19/2026 9:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 1/22/2026 4:10:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 55h 5m
Flix Mexico	58h 55m	9:05 PM	Santiago de Queretaro	Centro Comercial Galeria	8:00 AM	Chicago	Union Station	Economy	$222	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/19/2026 9:05:00 PM to Union Station, Chicago (USA) arriving at 1/22/2026 8:00:00 AM. 50 Economy ticket for $222 per person are available. Travel duration is 58h 55m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	57h 35m	10:35 AM	Santiago de Queretaro	Centro Comercial Galeria	8:10 PM	Chicago	Downtown Bus Station	Economy	$219	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/20/2026 10:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 1/22/2026 8:10:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 57h 35m
Flix Mexico	55h 5m	9:05 PM	Santiago de Queretaro	Centro Comercial Galeria	4:10 AM	Chicago	Downtown Bus Station	Economy	$219	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/20/2026 9:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 1/23/2026 4:10:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 55h 5m
Flix Mexico	54h 20m	1:40 AM	Santiago de Queretaro	Centro Comercial Galeria	8:00 AM	Chicago	Union Station	Economy	$219	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/20/2026 1:40:00 AM to Union Station, Chicago (USA) arriving at 1/22/2026 8:00:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 54h 20m
Flix Mexico	50h 30m	1:40 AM	Santiago de Queretaro	Centro Comercial Galeria	4:10 AM	Chicago	Downtown Bus Station	Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/20/2026 1:40:00 AM to Downtown Bus Station, Chicago (USA) arriving at 1/22/2026 4:10:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 50h 30m
Flix Mexico	56h 10m	1:40 AM	Santiago de Queretaro	Centro Comercial Galeria	9:50 AM	Chicago	95th Red Line Station	Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/20/2026 1:40:00 AM to 95th Red Line Station, Chicago (USA) arriving at 1/22/2026 9:50:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 56h 10m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	57h 35m	10:35 AM	Santiago de Queretaro	Centro Comercial Galeria	8:10 PM	Chicago	Downtown Bus Station	Economy	$219	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/22/2026 10:35:00 AM to Downtown Bus Station, Chicago (USA) arriving at 1/24/2026 8:10:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 57h 35m
Flix Mexico	56h 55m	11:05 PM	Santiago de Queretaro	Centro Comercial Galeria	8:00 AM	Chicago	Union Station	Economy	$219	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/22/2026 11:05:00 PM to Union Station, Chicago (USA) arriving at 1/25/2026 8:00:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 56h 55m
Flix Mexico	53h 5m	11:05 PM	Santiago de Queretaro	Centro Comercial Galeria	4:10 AM	Chicago	Downtown Bus Station	Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/22/2026 11:05:00 PM to Downtown Bus Station, Chicago (USA) arriving at 1/25/2026 4:10:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 53h 5m
Flix Mexico	61h 0m	10:35 AM	Santiago de Queretaro	Centro Comercial Galeria	11:35 PM	Chicago	95th Red Line Station	Economy	$221	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/22/2026 10:35:00 AM to 95th Red Line Station, Chicago (USA) arriving at 1/24/2026 11:35:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 61h 0m
Flix Mexico	54h 15m	11:05 PM	Santiago de Queretaro	Centro Comercial Galeria	5:20 AM	Chicago	95th Red Line Station	Economy	$221	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/22/2026 11:05:00 PM to 95th Red Line Station, Chicago (USA) arriving at 1/25/2026 5:20:00 AM. 50 Economy ticket for $221 per person are available. Travel duration is 54h 15m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Flix Mexico	51h 40m	1:40 AM	Santiago de Queretaro	Centro Comercial Galeria	5:20 AM	Chicago	95th Red Line Station	Economy	$219	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/24/2026 1:40:00 AM to 95th Red Line Station, Chicago (USA) arriving at 1/26/2026 5:20:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 51h 40m
Flix Mexico	54h 15m	11:05 PM	Santiago de Queretaro	Centro Comercial Galeria	5:20 AM	Chicago	95th Red Line Station	Economy	$220	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/24/2026 11:05:00 PM to 95th Red Line Station, Chicago (USA) arriving at 1/27/2026 5:20:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 54h 15m
Flix Mexico	59h 0m	12:35 PM	Santiago de Queretaro	Centro Comercial Galeria	11:35 PM	Chicago	95th Red Line Station	Economy	$221	A Bus from Flix Mexico goes from Centro Comercial Galeria, Santiago de Queretaro (Mexico) at 1/24/2026 12:35:00 PM to 95th Red Line Station, Chicago (USA) arriving at 1/26/2026 11:35:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 59h 0m

Best Price Offer: The price for the cheapest bus from Santiago de Queretaro to Chicago is $219 on 1/19/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Santiago de Queretaro and Chicago

See here how frequent the connections between Santiago de Queretaro and Chicago are, during different times and days of the week.

Thursday is the busiest day, with more than 8 daily buses from Santiago de Queretaro to Chicago. Monday has instead the fewest connections, with only 3 daily coaches between Santiago de Queretaro and Chicago.

The busiest time of the day is the Evening, with 10 buses from Santiago de Queretaro to Chicago, while Afternoon sees the fewest connections between Santiago de Queretaro and Chicago, with 2 offers.

Facts about the bus from Santiago de Queretaro to Chicago

Compare all providers like Flix Mexico that travel 5 times every day by bus from Santiago de Queretaro to Chicago in one click! Book your bus ticket from Santiago de Queretaro to Chicago starting from $219!

Cheapest Bus	$219
Fastest Bus	50h 30m
Earliest Bus	12:35 PM
Latest Bus	11:05 PM
Daily Bus Routes	5 Ø
Distance	1,648.5 miles
Bus Companies	Flix Mexico

Cheapest bus connections from Santiago de Queretaro to Chicago

Every day, 5 buses from 1 bus companies leave Santiago de Queretaro for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/18

Monday 01/19

$219

Tuesday 01/20

$220

Wednesday 01/21

Thursday 01/22

$219

Friday 01/23

Saturday 01/24

$219

Sunday 01/25

Monday 01/26

Tuesday 01/27

$220

Wednesday 01/28

Thursday 01/29

Friday 01/30

Saturday 01/31

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

The cheapest time to travel from Santiago de Queretaro to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago de Queretaro to Chicago, for the next 30 days.

With a price starting from $219, Monday is the cheapest day for a bus from Santiago de Queretaro to Chicago. Saturday instead is the most expensive day with prices starting from $219.

Morning is the cheapest day time for bus tickets from Santiago de Queretaro to Chicago, with $219. Morning is the most expensive time of the day with prices starting from $219.

How to save money travelling from Santiago de Queretaro to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago de Queretaro to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago de Queretaro to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santiago de Queretaro to Chicago are also emptier.

All bus stations and stops in Santiago de Queretaro and Chicago

In the map below, you can see where to find all bus stations in Santiago de Queretaro and Chicago.

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

El Colorado

Walmart Juriquilla

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Santiago de Queretaro to Chicago

Want to know which seat classes are available on the buses from Santiago de Queretaro to Chicago? Or which bus companies serve the route Santiago de Queretaro to Chicago? Below you will find answers to your questions.

FAQs about the Santiago de Queretaro to Chicago bus

How much does a Santiago de Queretaro Chicago bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $219 and takes 55h 35m to reach Chicago. Compare offers to save money!

How much could I save by comparing buses from Santiago de Queretaro to Chicago?

This route is offered by 1 companies with a range of ticket prices between $219 and $222. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Chicago.

On average, how many connections are available from Santiago de Queretaro to Chicago each day?

Every day, the Santiago de Queretaro to Chicago bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santiago de Queretaro to Chicago take?

The fastest bus from Santiago de Queretaro to Chicago is offered by Flix Mexico and takes 50h 30m. Bus tickets for this connection cost $220. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santiago de Queretaro to Chicago?

The earliest bus arriving in Chicago from Santiago de Queretaro starts at 12:35 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santiago de Queretaro to Chicago?

The latest bus trip departing from Santiago de Queretaro for Chicago starts at 11:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santiago de Queretaro Chicago route?

When traveling by bus from Santiago de Queretaro to Chicago, passengers can travel with Flix Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santiago de Queretaro and Chicago?

You can check all the direct connections between Santiago de Queretaro and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Flix Mexico.

What can I take with me on the Santiago de Queretaro to Chicago bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santiago de Queretaro Chicago bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago de Queretaro Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago de Queretaro to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago de Queretaro to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Santiago de Queretaro and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago de Queretaro to Chicago?

Prices and availability for 5 trips between Santiago de Queretaro and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago de Queretaro to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Santiago de Queretaro and to Chicago

Here’s an overview of the most popular bus routes to Santiago de Queretaro and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!