Bus from Cincinnati to St. Louis, MO from $53

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Compare all timetables for the bus from Cincinnati to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Cincinnati to St. Louis, MO from various bus operators like Greyhound US for the next days.
today
from $53
tomorrow
Saturday
Sunday
Monday
from $61
Tuesday
from $71
Wednesday

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    6h 35m
    0
    5:00 PM
    Cincinnati
    Greyhound Bus Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $53
  • Greyhound US
    13h 10m
    0
    10:25 AM
    Cincinnati
    Downtown
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $75

Cheapest bus trips Monday

Prices are for one way and one person
  • Greyhound US
    6h 35m
    0
    5:00 PM
    Cincinnati
    E Galbraith Rd
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $61

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    13h 10m
    0
    10:25 AM
    Cincinnati
    Downtown
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $71
  • Greyhound US
    6h 35m
    0
    5:00 PM
    Cincinnati
    Greyhound Bus Station
    11:35 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $72
  • Did you know that if you travel from Cincinnati to St. Louis, MO via Indianapolis, you can save more than $14? You can find the corresponding connections below.
    • Busbud
      6h 35m
      0
      5:00 PM
      Cincinnati
      E Galbraith Rd
      7:10 PM
      Indianapolis
      Central Bus Station
      0
      Busbud
      Economy
      $24
      • Waiting Time 0h 55m
    • Busbud
      3h 30m
      0
      8:05 PM
      Indianapolis
      Central Bus Station
      11:35 PM
      St. Louis, MO
      Gateway Station
      0
      Busbud
      Economy
      $33
    Travel time is the same as the direct connection, but you will save $14

Frequency of bus connections between Cincinnati and St. Louis, MO

See here how frequent the connections between Cincinnati and St. Louis, MO are, during different times and days of the week.
Tuesday is the busiest day, with more than 2 daily buses from Cincinnati to St. Louis, MO. Monday has instead the fewest connections, with only 1 daily coaches between Cincinnati and St. Louis, MO.
The busiest time of the day is the Afternoon, with 3 buses from Cincinnati to St. Louis, MO, while Morning sees the fewest connections between Cincinnati and St. Louis, MO, with 2 offers.

Facts about the bus from Cincinnati to St. Louis, MO

Compare all providers like Greyhound US that travel 1 times every day by bus from Cincinnati to St. Louis, MO in one click! Book your bus ticket from Cincinnati to St. Louis, MO starting from $53!

Cheapest Bus $53
Fastest Bus 6h 35m
Earliest Bus 10:25 AM
Latest Bus 5:00 PM
Daily Bus Routes 1 Ø
Distance 307.2 miles
Bus Companies Greyhound US

Cheapest bus connections from Cincinnati to St. Louis, MO

Every day, 1 buses from 1 bus companies leave Cincinnati for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/22/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/18
Monday 05/19
Tuesday 05/20
Wednesday 05/21
Thursday 05/22
$53
Friday 05/23
Saturday 05/24
Sunday 05/25
Monday 05/26
$60
Tuesday 05/27
$71
Wednesday 05/28
Thursday 05/29
$47
Friday 05/30
Saturday 05/31
Sunday 06/01
Monday 06/02
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
Friday 06/06
Saturday 06/07
Sunday 06/08
Monday 06/09
Tuesday 06/10
Wednesday 06/11
Thursday 06/12
Friday 06/13
Saturday 06/14

The cheapest time to travel from Cincinnati to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Cincinnati to St. Louis, MO, for the next 30 days.
With a price starting from $53, Thursday is the cheapest day for a bus from Cincinnati to St. Louis, MO. Tuesday instead is the most expensive day with prices starting from $71.
Afternoon is the cheapest day time for bus tickets from Cincinnati to St. Louis, MO, with $53. Morning is the most expensive time of the day with prices starting from $71.

How to save money travelling from Cincinnati to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Cincinnati to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Cincinnati to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Cincinnati to St. Louis, MO are also emptier.

Beloved bus companies from Cincinnati to St. Louis, MO

These are the most booked bus companies between Cincinnati to St. Louis, MO from our users.

Greyhound US from Cincinnati to St. Louis, MO

Greyhound US

Here you will find the key facts about the Greyhound US bus route Cincinnati to St. Louis, MO:

Cheapest Price $53
Fastest Bus 6h 35m
Earliest Bus 10:25 AM
Last Bus 5:00 PM
Daily Connections 1 Ø
Found on 5/18/2025

All bus stations and stops in Cincinnati and St. Louis, MO

In the map below, you can see where to find all bus stations in Cincinnati and St. Louis, MO.

Service and Comfort on the bus from Cincinnati to St. Louis, MO

Want to know which seat classes are available on the buses from Cincinnati to St. Louis, MO? Or which bus companies serve the route Cincinnati to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Cincinnati to St. Louis, MO bus

How much does a Cincinnati St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $53 and takes 6h 35m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Cincinnati to St. Louis, MO?

This route is offered by 1 companies with a range of ticket prices between $53 and $75. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Cincinnati to St. Louis, MO each day?

Every day, the Cincinnati to St. Louis, MO bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Cincinnati to St. Louis, MO take?

The fastest bus from Cincinnati to St. Louis, MO is offered by Greyhound US and takes 6h 35m. Bus tickets for this connection cost $53. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Cincinnati to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Cincinnati starts at 10:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Cincinnati to St. Louis, MO?

The latest bus trip departing from Cincinnati for St. Louis, MO starts at 5:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Cincinnati St. Louis, MO route?

When traveling by bus from Cincinnati to St. Louis, MO, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Cincinnati and St. Louis, MO?

You can check all the direct connections between Cincinnati and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Cincinnati to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Cincinnati St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Cincinnati St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Cincinnati to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Cincinnati to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Cincinnati and to St. Louis, MO

Here’s an overview of the most popular bus routes to Cincinnati and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Cleveland - Cincinnati Bus Cleveland - Cincinnati
Buses Detroit - Cincinnati Buses Detroit - Cincinnati
Bus Nashville to Cincinnati Bus Nashville to Cincinnati
Pittsburgh to Cincinnati bus Pittsburgh to Cincinnati bus
Buses from Nashville to St. Louis, MO Buses from Nashville to St. Louis, MO
From Memphis to St. Louis, MO bus From Memphis to St. Louis, MO bus
Indianapolis to St. Louis, MO bus Indianapolis to St. Louis, MO bus
Bus Springfield, MO - St. Louis, MO Bus Springfield, MO - St. Louis, MO
Popular Airport Shuttles to Cincinnati and to St. Louis, MO
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