Bus Cincinnati to St. Louis, MO - Compare all Companies

Compare all timetables for the bus from Cincinnati to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Cincinnati to St. Louis, MO from various bus operators like Greyhound US or FlixBus for the next days.

today

$48

tomorrow

$54

Wednesday

$50

Thursday

$48

Friday

Saturday

$52

Sunday

$65

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 10m	7:00 AM	Cincinnati	University of Cincinnati	11:10 PM	St. Louis, MO	Gateway Station	Economy	$48	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 1/26/2026 7:00:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/26/2026 11:10:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 17h 10m
FlixBus	16h 55m	7:15 AM	Cincinnati	Downtown	11:10 PM	St. Louis, MO	Gateway Station	Economy	$48	A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 1/26/2026 7:15:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/26/2026 11:10:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 16h 55m
Greyhound US	14h 20m	10:05 AM	Cincinnati	E Galbraith Rd	11:25 PM	St. Louis, MO	Gateway Station	Economy	$48	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 1/26/2026 10:05:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/26/2026 11:25:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 14h 20m
Greyhound US	14h 0m	10:25 AM	Cincinnati	Downtown	11:25 PM	St. Louis, MO	Gateway Station	Economy	$49	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 1/26/2026 10:25:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/26/2026 11:25:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 14h 0m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 25m	12:55 AM	Cincinnati	Greyhound Bus Station	3:20 PM	St. Louis, MO	Gateway Station	Economy	$54	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 1/27/2026 12:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/27/2026 3:20:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 15h 25m
Greyhound US	14h 20m	10:05 AM	Cincinnati	Greyhound Bus Station	11:25 PM	St. Louis, MO	Gateway Station	Economy	$54	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 1/27/2026 10:05:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/27/2026 11:25:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 14h 20m
Greyhound US	14h 0m	10:25 AM	Cincinnati	Downtown	11:25 PM	St. Louis, MO	Gateway Station	Economy	$54	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 1/27/2026 10:25:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/27/2026 11:25:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 14h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 25m	12:55 AM	Cincinnati	E Galbraith Rd	3:20 PM	St. Louis, MO	Gateway Station	Economy	$50	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 1/28/2026 12:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/28/2026 3:20:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 15h 25m
Greyhound US	14h 20m	10:05 AM	Cincinnati	E Galbraith Rd	11:25 PM	St. Louis, MO	Gateway Station	Economy	$50	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 1/28/2026 10:05:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/28/2026 11:25:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 14h 20m
Greyhound US	14h 0m	10:25 AM	Cincinnati	Downtown	11:25 PM	St. Louis, MO	Gateway Station	Economy	$50	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 1/28/2026 10:25:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/28/2026 11:25:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 14h 0m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 25m	12:55 AM	Cincinnati	Greyhound Bus Station	3:20 PM	St. Louis, MO	Gateway Station	Economy	$48	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 1/29/2026 12:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/29/2026 3:20:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 15h 25m
Greyhound US	14h 20m	10:05 AM	Cincinnati	Greyhound Bus Station	11:25 PM	St. Louis, MO	Gateway Station	Economy	$49	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 1/29/2026 10:05:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/29/2026 11:25:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 14h 20m
Greyhound US	14h 0m	10:25 AM	Cincinnati	Downtown	11:25 PM	St. Louis, MO	Gateway Station	Economy	$49	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 1/29/2026 10:25:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/29/2026 11:25:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 14h 0m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 20m	10:05 AM	Cincinnati	E Galbraith Rd	11:25 PM	St. Louis, MO	Gateway Station	Economy	$52	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 1/31/2026 10:05:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/31/2026 11:25:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 20m
Greyhound US	14h 0m	10:25 AM	Cincinnati	Downtown	11:25 PM	St. Louis, MO	Gateway Station	Economy	$52	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 1/31/2026 10:25:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/31/2026 11:25:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 14h 0m
FlixBus	17h 10m	7:00 AM	Cincinnati	University of Cincinnati	11:10 PM	St. Louis, MO	Gateway Station	Economy	$52	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 1/31/2026 7:00:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/31/2026 11:10:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 17h 10m
FlixBus	16h 55m	7:15 AM	Cincinnati	Downtown	11:10 PM	St. Louis, MO	Gateway Station	Economy	$52	A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 1/31/2026 7:15:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/31/2026 11:10:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 16h 55m
Greyhound US	15h 25m	12:55 AM	Cincinnati	E Galbraith Rd	3:20 PM	St. Louis, MO	Gateway Station	Economy	$54	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 1/31/2026 12:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 1/31/2026 3:20:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 15h 25m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	17h 10m	7:00 AM	Cincinnati	University of Cincinnati	11:10 PM	St. Louis, MO	Gateway Station	Economy	$65	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 2/1/2026 7:00:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 2/1/2026 11:10:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 17h 10m
FlixBus	16h 55m	7:15 AM	Cincinnati	Downtown	11:10 PM	St. Louis, MO	Gateway Station	Economy	$65	A Bus from FlixBus goes from Downtown, Cincinnati (USA) at 2/1/2026 7:15:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 2/1/2026 11:10:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 16h 55m
Greyhound US	15h 25m	12:55 AM	Cincinnati	Greyhound Bus Station	3:20 PM	St. Louis, MO	Gateway Station	Economy	$66	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 2/1/2026 12:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 2/1/2026 3:20:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 15h 25m
Greyhound US	14h 20m	10:05 AM	Cincinnati	Greyhound Bus Station	11:25 PM	St. Louis, MO	Gateway Station	Economy	$66	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 2/1/2026 10:05:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 2/1/2026 11:25:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 14h 20m
Greyhound US	14h 0m	10:25 AM	Cincinnati	Downtown	11:25 PM	St. Louis, MO	Gateway Station	Economy	$66	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 2/1/2026 10:25:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 2/1/2026 11:25:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 14h 0m

Best Price Offer: The price for the cheapest bus from Cincinnati to St. Louis, MO is $48 on 2/5/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Cincinnati and St. Louis, MO

See here how frequent the connections between Cincinnati and St. Louis, MO are, during different times and days of the week.

Saturday is the busiest day, with more than 10 daily buses from Cincinnati to St. Louis, MO. Tuesday has instead the fewest connections, with only 3 daily coaches between Cincinnati and St. Louis, MO.

The busiest time of the day is the Morning, with 28 buses from Cincinnati to St. Louis, MO, while Night sees the fewest connections between Cincinnati and St. Louis, MO, with 7 offers.

Facts about the bus from Cincinnati to St. Louis, MO

Compare all providers like Greyhound US and FlixBus that travel 5 times every day by bus from Cincinnati to St. Louis, MO in one click! Book your bus ticket from Cincinnati to St. Louis, MO starting from $48!

Cheapest Bus	$48
Fastest Bus	13h 0m
Earliest Bus	7:00 AM
Latest Bus	10:25 AM
Daily Bus Routes	5 Ø
Distance	307.2 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Cincinnati to St. Louis, MO

Every day, 5 buses from 2 bus companies leave Cincinnati for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/26/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 01/25

Monday 01/26

$48

Tuesday 01/27

$54

Wednesday 01/28

$50

Thursday 01/29

$48

Friday 01/30

Saturday 01/31

$52

Sunday 02/01

$65

Monday 02/02

$59

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

$48

Friday 02/06

Saturday 02/07

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

Saturday 02/14

Sunday 02/15

Monday 02/16

Tuesday 02/17

Wednesday 02/18

Thursday 02/19

Friday 02/20

Saturday 02/21

The cheapest time to travel from Cincinnati to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Cincinnati to St. Louis, MO, for the next 30 days.

With a price starting from $48, Thursday is the cheapest day for a bus from Cincinnati to St. Louis, MO. Sunday instead is the most expensive day with prices starting from $65.

Night is the cheapest day time for bus tickets from Cincinnati to St. Louis, MO, with $48. Morning is the most expensive time of the day with prices starting from $48.

How to save money travelling from Cincinnati to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Cincinnati to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Cincinnati to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Cincinnati to St. Louis, MO are also emptier.

All bus stations and stops in Cincinnati and St. Louis, MO

In the map below, you can see where to find all bus stations in Cincinnati and St. Louis, MO.

Hughes STEM High School

2515 Clifton Ave

Bus Stop

Cassinelli Square

Princeton Pike, Cincinnati, OH 11376

Downtown

E Court St 419

E Galbraith Rd

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Service and Comfort on the bus from Cincinnati to St. Louis, MO

Want to know which seat classes are available on the buses from Cincinnati to St. Louis, MO? Or which bus companies serve the route Cincinnati to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Cincinnati to St. Louis, MO bus

How much does a Cincinnati St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $48 and takes 13h 20m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Cincinnati to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $48 and $66. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Cincinnati to St. Louis, MO each day?

Every day, the Cincinnati to St. Louis, MO bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Cincinnati to St. Louis, MO take?

The fastest bus from Cincinnati to St. Louis, MO is offered by Greyhound US and takes 13h 0m. Bus tickets for this connection cost $49. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Cincinnati to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Cincinnati starts at 7:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Cincinnati to St. Louis, MO?

The latest bus trip departing from Cincinnati for St. Louis, MO starts at 10:25 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Cincinnati St. Louis, MO route?

When traveling by bus from Cincinnati to St. Louis, MO, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Cincinnati and St. Louis, MO?

You can check all the direct connections between Cincinnati and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Cincinnati to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Cincinnati St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Cincinnati St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Cincinnati to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Cincinnati to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Cincinnati and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Cincinnati to St. Louis, MO?

Prices and availability for 5 trips between Cincinnati and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Cincinnati to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Cincinnati and to St. Louis, MO

Here’s an overview of the most popular bus routes to Cincinnati and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!