Bus Cincinnati to Tupelo, MS - Compare all Companies

Compare all timetables for the bus from Cincinnati to Tupelo, MS

Here is a selection of the cheapest bus trips from the schedule from Cincinnati to Tupelo, MS from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

Wednesday

$101

Thursday

$88

Friday

$92

Saturday

Sunday

$84

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	16h 30m	1:55 PM	Cincinnati	Greyhound Bus Station	5:25 AM	Tupelo, MS	Bus Stop	Economy	$101	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 4/22/2026 1:55:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 4/23/2026 5:25:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 16h 30m
Greyhound US	20h 0m	10:25 AM	Cincinnati	Downtown	5:25 AM	Tupelo, MS	Bus Stop	Economy	$101	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 4/22/2026 10:25:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/23/2026 5:25:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 20h 0m
Greyhound US	21h 30m	12:55 AM	Cincinnati	Greyhound Bus Station	9:25 PM	Tupelo, MS	Bus Stop	Economy	$102	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 4/22/2026 12:55:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/22/2026 9:25:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 21h 30m

Did you know that if you travel from Cincinnati to Tupelo, MS via Nashville, you can save more than $17? You can find the corresponding connections below.
- Greyhound US
  
  20h 0m
  
  0
  
  10:25 AM
  
  Cincinnati
  Downtown
  
  3:15 PM
  
  Nashville
  5th Ave South Station
  
  0
  
  Economy
  
  $38
  
  A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 4/21/2026 10:25:00 AM to 5th Ave South Station, Nashville (USA) arriving at 4/21/2026 3:15:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 5h 50m
- Greyhound US
  
  11h 40m
  
  0
  
  5:45 PM
  
  Nashville
  5th Ave South Station
  
  5:25 AM
  
  Tupelo, MS
  Bus Stop
  
  0
  
  Economy
  
  $46
  
  A Bus from Greyhound US goes from 5th Ave South Station, Nashville (USA) at 4/21/2026 5:45:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 4/22/2026 5:25:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 11h 40m
Travel time is 4h 30m longer, but you will save $17

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 30m	12:55 AM	Cincinnati	E Galbraith Rd	9:25 PM	Tupelo, MS	Bus Stop	Economy	$88	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 4/23/2026 12:55:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/23/2026 9:25:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 21h 30m
Greyhound US	16h 30m	1:55 PM	Cincinnati	E Galbraith Rd	5:25 AM	Tupelo, MS	Bus Stop	Economy	$88	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 4/23/2026 1:55:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 4/24/2026 5:25:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 16h 30m
FlixBus	28h 40m	7:00 AM	Cincinnati	University of Cincinnati	10:40 AM	Tupelo, MS	Bus Stop	Economy	$88	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 4/23/2026 7:00:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/24/2026 10:40:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 28h 40m
Greyhound US	20h 0m	10:25 AM	Cincinnati	Downtown	5:25 AM	Tupelo, MS	Bus Stop	Economy	$89	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 4/23/2026 10:25:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/24/2026 5:25:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 20h 0m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	16h 30m	1:55 PM	Cincinnati	Greyhound Bus Station	5:25 AM	Tupelo, MS	Bus Stop	Economy	$92	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 4/24/2026 1:55:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 4/25/2026 5:25:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 16h 30m
FlixBus	28h 40m	7:00 AM	Cincinnati	University of Cincinnati	10:40 AM	Tupelo, MS	Bus Stop	Economy	$92	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 4/24/2026 7:00:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/25/2026 10:40:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 28h 40m
Greyhound US	20h 0m	10:25 AM	Cincinnati	Downtown	5:25 AM	Tupelo, MS	Bus Stop	Economy	$93	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 4/24/2026 10:25:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/25/2026 5:25:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 20h 0m
Greyhound US	21h 30m	12:55 AM	Cincinnati	Greyhound Bus Station	9:25 PM	Tupelo, MS	Bus Stop	Economy	$94	A Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 4/24/2026 12:55:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/24/2026 9:25:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 21h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 30m	12:55 AM	Cincinnati	E Galbraith Rd	9:25 PM	Tupelo, MS	Bus Stop	Economy	$84	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 4/26/2026 12:55:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/26/2026 9:25:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 21h 30m
Greyhound US	20h 0m	10:25 AM	Cincinnati	Downtown	5:25 AM	Tupelo, MS	Bus Stop	Economy	$84	A Bus from Greyhound US goes from Downtown, Cincinnati (USA) at 4/26/2026 10:25:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/27/2026 5:25:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 20h 0m
FlixBus	28h 40m	7:00 AM	Cincinnati	University of Cincinnati	10:40 AM	Tupelo, MS	Bus Stop	Economy	$84	A Bus from FlixBus goes from University of Cincinnati, Cincinnati (USA) at 4/26/2026 7:00:00 AM to Bus Stop, Tupelo, MS (USA) arriving at 4/27/2026 10:40:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 28h 40m
Greyhound US	16h 30m	1:55 PM	Cincinnati	E Galbraith Rd	5:25 AM	Tupelo, MS	Bus Stop	Economy	$86	A Bus from Greyhound US goes from E Galbraith Rd, Cincinnati (USA) at 4/26/2026 1:55:00 PM to Bus Stop, Tupelo, MS (USA) arriving at 4/27/2026 5:25:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 30m

Best Price Offer: The price for the cheapest bus from Cincinnati to Tupelo, MS is $75 on 5/10/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Cincinnati and Tupelo, MS

See here how frequent the connections between Cincinnati and Tupelo, MS are, during different times and days of the week.

Sunday is the busiest day, with more than 8 daily buses from Cincinnati to Tupelo, MS. Wednesday has instead the fewest connections, with only 3 daily coaches between Cincinnati and Tupelo, MS.

The busiest time of the day is the Morning, with 9 buses from Cincinnati to Tupelo, MS, while Afternoon sees the fewest connections between Cincinnati and Tupelo, MS, with 5 offers.

Facts about the bus from Cincinnati to Tupelo, MS

Compare all providers like Greyhound US and FlixBus that travel 4 times every day by bus from Cincinnati to Tupelo, MS in one click! Book your bus ticket from Cincinnati to Tupelo, MS starting from $75!

Cheapest Bus	$75
Fastest Bus	15h 30m
Earliest Bus	12:55 AM
Latest Bus	1:55 PM
Daily Bus Routes	4 Ø
Distance	406.9 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Cincinnati to Tupelo, MS

Every day, 4 buses from 2 bus companies leave Cincinnati for Tupelo, MS: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

Tuesday 04/21

Wednesday 04/22

$101

Thursday 04/23

$88

Friday 04/24

$92

Saturday 04/25

Sunday 04/26

$84

Monday 04/27

Tuesday 04/28

Wednesday 04/29

$88

Thursday 04/30

Friday 05/01

$84

Saturday 05/02

$78

Sunday 05/03

$82

Monday 05/04

$79

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$80

Saturday 05/09

Sunday 05/10

$75

Monday 05/11

$78

Tuesday 05/12

$87

Wednesday 05/13

Thursday 05/14

$81

Friday 05/15

Saturday 05/16

The cheapest time to travel from Cincinnati to Tupelo, MS

See here on which day and which time of the day you can find the cheapest bus ticket from Cincinnati to Tupelo, MS, for the next 30 days.

With a price starting from $75, Sunday is the cheapest day for a bus from Cincinnati to Tupelo, MS. Wednesday instead is the most expensive day with prices starting from $88.

Night is the cheapest day time for bus tickets from Cincinnati to Tupelo, MS, with $75. Afternoon is the most expensive time of the day with prices starting from $86.

How to save money travelling from Cincinnati to Tupelo, MS

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Cincinnati to Tupelo, MS in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Cincinnati to Tupelo, MS, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Cincinnati to Tupelo, MS are also emptier.

All bus stations and stops in Cincinnati and Tupelo, MS

In the map below, you can see where to find all bus stations in Cincinnati and Tupelo, MS.

University of Cincinnati

Commons Way 2815

Greyhound Bus Station

Gilbert Ave 1005

E Galbraith Rd

Downtown

E Court St 419

Bus Stop

S Eason Blvd 2831

Service and Comfort on the bus from Cincinnati to Tupelo, MS

Want to know which seat classes are available on the buses from Cincinnati to Tupelo, MS? Or which bus companies serve the route Cincinnati to Tupelo, MS? Below you will find answers to your questions.

FAQs about the Cincinnati to Tupelo, MS bus

How much does a Cincinnati Tupelo, MS bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $75 and takes 27h 40m to reach Tupelo, MS. Compare offers to save money!

How much could I save by comparing buses from Cincinnati to Tupelo, MS?

This route is offered by 2 companies with a range of ticket prices between $75 and $102. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Tupelo, MS.

On average, how many connections are available from Cincinnati to Tupelo, MS each day?

Every day, the Cincinnati to Tupelo, MS bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Cincinnati to Tupelo, MS take?

The fastest bus from Cincinnati to Tupelo, MS is offered by Greyhound US and takes 15h 30m. Bus tickets for this connection cost $101. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Cincinnati to Tupelo, MS?

The earliest bus arriving in Tupelo, MS from Cincinnati starts at 12:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Cincinnati to Tupelo, MS?

The latest bus trip departing from Cincinnati for Tupelo, MS starts at 1:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Cincinnati Tupelo, MS route?

When traveling by bus from Cincinnati to Tupelo, MS, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Cincinnati and Tupelo, MS?

You can check all the direct connections between Cincinnati and Tupelo, MS by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Cincinnati to Tupelo, MS bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Cincinnati Tupelo, MS bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Cincinnati Tupelo, MS bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Cincinnati to Tupelo, MS on your planned travel date.

How does CheckMyBus find the best bus deals from Cincinnati to Tupelo, MS?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Cincinnati and Tupelo, MS. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Cincinnati to Tupelo, MS?

Prices and availability for 4 trips between Cincinnati and Tupelo, MS change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Cincinnati to Tupelo, MS

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Cincinnati and to Tupelo, MS

Here’s an overview of the most popular bus routes to Cincinnati and to Tupelo, MS. Simply click on the connection of your choice, and you will find all the details about your bus route!