Bus El Centro, CA to Santa Ana, CA - Compare all Companies

Compare all timetables for the bus from El Centro, CA to Santa Ana, CA

Here is a selection of the cheapest bus trips from the schedule from El Centro, CA to Santa Ana, CA from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$53

Tuesday

$44

Wednesday

$37

Thursday

Friday

Saturday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	6h 5m	3:15 PM	El Centro, CA	Bus Stop	9:20 PM	Santa Ana, CA	Bus Stop		Economy	$53	A Bus from Greyhound US goes from Bus Stop, El Centro, CA (USA) at 3/23/2026 3:15:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 3/23/2026 9:20:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 6h 5m
	FlixBus	9h 55m	9:35 AM	El Centro, CA	Bus Stop	7:30 PM	Santa Ana, CA	Bus Stop		Economy	$57	A Bus from FlixBus goes from Bus Stop, El Centro, CA (USA) at 3/23/2026 9:35:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 3/23/2026 7:30:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 9h 55m

Did you know that if you travel from El Centro, CA to Santa Ana, CA via Calexico, CA, you can save more than $16? You will find the corresponding connections below.
- Save more than 30%
  
  6h 40m
  
  El Centro, CA
  
  9 mi
  
  2:40 PM
  
  Calexico, CA
  Bus Station
  
  9:20 PM
  
  Santa Ana, CA
  Bus Stop
  
  0 mi
  
  Economy
  
  $37
  
  A Bus from goes from Bus Station, Calexico, CA (USA) at 3/23/2026 2:40:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 3/23/2026 9:20:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 6h 40m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	9h 55m	9:35 AM	El Centro, CA	Bus Stop	7:30 PM	Santa Ana, CA	Bus Stop		Economy	$44	A Bus from FlixBus goes from Bus Stop, El Centro, CA (USA) at 3/24/2026 9:35:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 3/24/2026 7:30:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 55m
	Greyhound US	6h 5m	3:15 PM	El Centro, CA	Bus Stop	9:20 PM	Santa Ana, CA	Bus Stop		Economy	$44	A Bus from Greyhound US goes from Bus Stop, El Centro, CA (USA) at 3/24/2026 3:15:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 3/24/2026 9:20:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 6h 5m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	9h 55m	9:35 AM	El Centro, CA	Bus Stop	7:30 PM	Santa Ana, CA	Bus Stop		Economy	$37	A Bus from FlixBus goes from Bus Stop, El Centro, CA (USA) at 3/25/2026 9:35:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 3/25/2026 7:30:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 9h 55m

Best Price Offer: The price for the cheapest bus from El Centro, CA to Santa Ana, CA is $33 on 4/7/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between El Centro, CA and Santa Ana, CA

See here how frequent the connections between El Centro, CA and Santa Ana, CA are, during different times and days of the week.

Monday is the busiest day, with more than 2 daily buses from El Centro, CA to Santa Ana, CA. Wednesday has instead the fewest connections, with only 1 daily coaches between El Centro, CA and Santa Ana, CA.

The busiest time of the day is the Morning, with 3 buses from El Centro, CA to Santa Ana, CA, while Afternoon sees the fewest connections between El Centro, CA and Santa Ana, CA, with 2 offers.

Facts about the bus from El Centro, CA to Santa Ana, CA

Compare all providers like FlixBus and Greyhound US that travel 1 times every day by bus from El Centro, CA to Santa Ana, CA in one click! Book your bus ticket from El Centro, CA to Santa Ana, CA starting from $33!

Cheapest Bus	$33
Fastest Bus	6h 5m
Earliest Bus	9:35 AM
Latest Bus	9:35 AM
Daily Bus Routes	1 Ø
Distance	148.6 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from El Centro, CA to Santa Ana, CA

Every day, 1 buses from 2 bus companies leave El Centro, CA for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/22

Monday 03/23

$53

Tuesday 03/24

$44

Wednesday 03/25

$37

Thursday 03/26

Friday 03/27

Saturday 03/28

Sunday 03/29

Monday 03/30

Tuesday 03/31

Wednesday 04/01

Thursday 04/02

$42

Friday 04/03

Saturday 04/04

$39

Sunday 04/05

$41

Monday 04/06

$40

Tuesday 04/07

$33

Wednesday 04/08

$33

Thursday 04/09

$41

Friday 04/10

$43

Saturday 04/11

$44

Sunday 04/12

$43

Monday 04/13

$45

Tuesday 04/14

$39

Wednesday 04/15

$34

Thursday 04/16

Friday 04/17

$36

Saturday 04/18

The cheapest time to travel from El Centro, CA to Santa Ana, CA

See here on which day and which time of the day you can find the cheapest bus ticket from El Centro, CA to Santa Ana, CA, for the next 30 days.

With a price starting from $33, Tuesday is the cheapest day for a bus from El Centro, CA to Santa Ana, CA. Monday instead is the most expensive day with prices starting from $40.

Morning is the cheapest day time for bus tickets from El Centro, CA to Santa Ana, CA, with $37. Afternoon is the most expensive time of the day with prices starting from $44.

How to save money travelling from El Centro, CA to Santa Ana, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from El Centro, CA to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from El Centro, CA to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from El Centro, CA to Santa Ana, CA are also emptier.

Beloved bus companies from El Centro, CA to Santa Ana, CA

These are the most booked bus companies between El Centro, CA to Santa Ana, CA from our users.

Greyhound US from El Centro, CA to Santa Ana, CA

Here you will find the key facts about the Greyhound US bus route El Centro, CA to Santa Ana, CA:

Cheapest Price	$44
Fastest Bus	6h 5m
Earliest Bus	3:15 PM
Last Bus	3:15 PM
Daily Connections	1 Ø
Found on	3/18/2026

All bus stations and stops in El Centro, CA and Santa Ana, CA

In the map below, you can see where to find all bus stations in El Centro, CA and Santa Ana, CA.

Bus Stop

State St 460

Imperial Valley Mall

Wake Ave

Bus Stop

1000 E Santa Ana Blvd 105

Service and Comfort on the bus from El Centro, CA to Santa Ana, CA

Want to know which seat classes are available on the buses from El Centro, CA to Santa Ana, CA? Or which bus companies serve the route El Centro, CA to Santa Ana, CA? Below you will find answers to your questions.

FAQs about the El Centro, CA to Santa Ana, CA bus

How much does a El Centro, CA Santa Ana, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $33 and takes 9h 55m to reach Santa Ana, CA. Compare offers to save money!

How much could I save by comparing buses from El Centro, CA to Santa Ana, CA?

This route is offered by 2 companies with a range of ticket prices between $33 and $57. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana, CA.

On average, how many connections are available from El Centro, CA to Santa Ana, CA each day?

Every day, the El Centro, CA to Santa Ana, CA bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from El Centro, CA to Santa Ana, CA take?

The fastest bus from El Centro, CA to Santa Ana, CA is offered by Greyhound US and takes 6h 5m. Bus tickets for this connection cost $53. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from El Centro, CA to Santa Ana, CA?

The earliest bus arriving in Santa Ana, CA from El Centro, CA starts at 9:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from El Centro, CA to Santa Ana, CA?

The latest bus trip departing from El Centro, CA for Santa Ana, CA starts at 9:35 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the El Centro, CA Santa Ana, CA route?

When traveling by bus from El Centro, CA to Santa Ana, CA, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between El Centro, CA and Santa Ana, CA?

You can check all the direct connections between El Centro, CA and Santa Ana, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the El Centro, CA to Santa Ana, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the El Centro, CA Santa Ana, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the El Centro, CA Santa Ana, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from El Centro, CA to Santa Ana, CA on your planned travel date.

How does CheckMyBus find the best bus deals from El Centro, CA to Santa Ana, CA?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between El Centro, CA and Santa Ana, CA. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from El Centro, CA to Santa Ana, CA?

Prices and availability for 1 trips between El Centro, CA and Santa Ana, CA change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route El Centro, CA to Santa Ana, CA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to El Centro, CA and to Santa Ana, CA

Here’s an overview of the most popular bus routes to El Centro, CA and to Santa Ana, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!