Bus Fort Myers, FL to Lake City, FL - Compare all Companies

Compare all timetables for the bus from Fort Myers, FL to Lake City, FL

Here is a selection of the cheapest bus trips from the schedule from Fort Myers, FL to Lake City, FL from various bus operators like FlixBus for the next days.

today

tomorrow

Sunday

Monday

Tuesday

Wednesday

$75

Thursday

$78

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	14h 40m	6:20 PM	Fort Myers, FL	Rosa Parks Transit Center	9:00 AM	Lake City, FL	Bus Stop		Economy	$75	A Bus from FlixBus goes from Rosa Parks Transit Center, Fort Myers, FL (USA) at 12/10/2025 6:20:00 PM to Bus Stop, Lake City, FL (USA) arriving at 12/11/2025 9:00:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 14h 40m

Did you know that if you travel from Fort Myers, FL to Lake City, FL via Orlando, FL, you can save more than $20? You can find the corresponding connections below.
- Busbud
  
  16h 35m
  
  0
  
  4:25 PM
  
  Fort Myers, FL
  Rosa Parks Transit Center
  
  10:10 PM
  
  Orlando, FL
  Bus Station
  
  0
  
  Economy
  
  $27
  
  A Bus from Busbud goes from Rosa Parks Transit Center, Fort Myers, FL (USA) at 12/7/2025 4:25:00 PM to Bus Station, Orlando, FL (USA) arriving at 12/7/2025 10:10:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 45m
- FlixBus
  
  3h 45m
  
  0
  
  5:15 AM
  
  Orlando, FL
  Bus Station
  
  9:00 AM
  
  Lake City, FL
  Bus Stop
  
  0
  
  Economy
  
  $28
  
  A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 5:15:00 AM to Bus Stop, Lake City, FL (USA) arriving at 12/8/2025 9:00:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 3h 45m
Travel time is 1h 55m longer, but you will save $20

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	14h 30m	6:30 PM	Fort Myers, FL	Rosa Parks Transit Center	9:00 AM	Lake City, FL	Bus Stop		Economy	$78	A Bus from FlixBus goes from Rosa Parks Transit Center, Fort Myers, FL (USA) at 12/11/2025 6:30:00 PM to Bus Stop, Lake City, FL (USA) arriving at 12/12/2025 9:00:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 14h 30m

Did you know that if you travel from Fort Myers, FL to Lake City, FL via Orlando, FL, you can save more than $23? You can find the corresponding connections below.
- Busbud
  
  16h 35m
  
  0
  
  4:25 PM
  
  Fort Myers, FL
  Rosa Parks Transit Center
  
  10:10 PM
  
  Orlando, FL
  Bus Station
  
  0
  
  Economy
  
  $27
  
  A Bus from Busbud goes from Rosa Parks Transit Center, Fort Myers, FL (USA) at 12/7/2025 4:25:00 PM to Bus Station, Orlando, FL (USA) arriving at 12/7/2025 10:10:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 45m
- FlixBus
  
  3h 45m
  
  0
  
  5:15 AM
  
  Orlando, FL
  Bus Station
  
  9:00 AM
  
  Lake City, FL
  Bus Stop
  
  0
  
  Economy
  
  $28
  
  A Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 5:15:00 AM to Bus Stop, Lake City, FL (USA) arriving at 12/8/2025 9:00:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 3h 45m
Travel time is 2h 5m longer, but you will save $23

Best Price Offer: The price for the cheapest bus from Fort Myers, FL to Lake City, FL is $75 on 12/10/2025. Flexible travelers save on ticket prices.

Facts about the bus from Fort Myers, FL to Lake City, FL

Compare all providers like FlixBus that travel 1 times every day by bus from Fort Myers, FL to Lake City, FL in one click! Book your bus ticket from Fort Myers, FL to Lake City, FL starting from $75!

Cheapest Bus	$75
Fastest Bus	14h 30m
Earliest Bus	6:20 PM
Latest Bus	6:30 PM
Daily Bus Routes	1 Ø
Distance	249.7 miles
Bus Companies	FlixBus

Cheapest bus connections from Fort Myers, FL to Lake City, FL

Every day, 1 buses from 1 bus companies leave Fort Myers, FL for Lake City, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

Saturday 12/06

Sunday 12/07

Monday 12/08

Tuesday 12/09

Wednesday 12/10

$75

Thursday 12/11

$78

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

How to save money travelling from Fort Myers, FL to Lake City, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Fort Myers, FL to Lake City, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Fort Myers, FL to Lake City, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Fort Myers, FL to Lake City, FL are also emptier.

Beloved bus companies from Fort Myers, FL to Lake City, FL

These are the most booked bus companies between Fort Myers, FL to Lake City, FL from our users.

FlixBus from Fort Myers, FL to Lake City, FL

Here you will find the key facts about the FlixBus bus route Fort Myers, FL to Lake City, FL:

Cheapest Price	$75
Fastest Bus	14h 30m
Earliest Bus	6:20 PM
Last Bus	6:30 PM
Daily Connections	1 Ø
Found on	12/3/2025

All bus stations and stops in Fort Myers, FL and Lake City, FL

In the map below, you can see where to find all bus stations in Fort Myers, FL and Lake City, FL.

Bus Station

Plaza Drive 6050

Rosa Parks Transit Center

Widman Way 2250

Daniels Pkwy

Florida Gulf Coast University

Parking Lot Five

Cleveland Ave

Bus Stop

S Marion Ave 251

Lake City Bus Stop

Service and Comfort on the bus from Fort Myers, FL to Lake City, FL

Want to know which seat classes are available on the buses from Fort Myers, FL to Lake City, FL? Or which bus companies serve the route Fort Myers, FL to Lake City, FL? Below you will find answers to your questions.

FAQs about the Fort Myers, FL to Lake City, FL bus

How much does a Fort Myers, FL Lake City, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $75 and takes 14h 40m to reach Lake City, FL. Compare offers to save money!

How much could I save by comparing buses from Fort Myers, FL to Lake City, FL?

This route is offered by 1 companies with a range of ticket prices between $75 and $78. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lake City, FL.

On average, how many connections are available from Fort Myers, FL to Lake City, FL each day?

Every day, the Fort Myers, FL to Lake City, FL bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Fort Myers, FL to Lake City, FL take?

The fastest bus from Fort Myers, FL to Lake City, FL is offered by FlixBus and takes 14h 30m. Bus tickets for this connection cost $78. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Fort Myers, FL to Lake City, FL?

The earliest bus arriving in Lake City, FL from Fort Myers, FL starts at 6:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Fort Myers, FL to Lake City, FL?

The latest bus trip departing from Fort Myers, FL for Lake City, FL starts at 6:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Fort Myers, FL Lake City, FL route?

When traveling by bus from Fort Myers, FL to Lake City, FL, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Fort Myers, FL and Lake City, FL?

You can check all the direct connections between Fort Myers, FL and Lake City, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Fort Myers, FL to Lake City, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Fort Myers, FL Lake City, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Fort Myers, FL Lake City, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Fort Myers, FL to Lake City, FL on your planned travel date.

Available seat classes which are offered on the bus route Fort Myers, FL to Lake City, FL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Fort Myers, FL and to Lake City, FL

Here’s an overview of the most popular bus routes to Fort Myers, FL and to Lake City, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!