Bus Greenville, SC to Birmingham, AL: Compare prices and save money

Compare all timetables for the bus from Greenville, SC to Birmingham, AL

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Birmingham, AL from various bus operators like FlixBus or Greyhound US for the next days.

today

$38

tomorrow

$42

Saturday

$43

Sunday

$49

Monday

Tuesday

Wednesday

$43

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 25m	8:40 AM	Greenville, SC	Woodruff Rd	2:05 PM	Birmingham, AL	MAX Central Station	Economy	$38	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/4/2026 8:40:00 AM to MAX Central Station, Birmingham, AL (USA) arriving at 6/4/2026 2:05:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 6h 25m
FlixBus	5h 50m	1:20 PM	Greenville, SC	Woodruff Rd	6:10 PM	Birmingham, AL	MAX Central Station	Economy	$38	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/4/2026 1:20:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/4/2026 6:10:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 5h 50m
Greyhound US	7h 55m	2:45 PM	Greenville, SC	Woodruff Rd	9:40 PM	Birmingham, AL	MAX Central Station	Economy	$38	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/4/2026 2:45:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/4/2026 9:40:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 55m
FlixBus	10h 5m	10:00 PM	Greenville, SC	Woodruff Rd	7:05 AM	Birmingham, AL	MAX Central Station	Economy	$41	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/4/2026 10:00:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/5/2026 7:05:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 10h 5m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 25m	8:40 AM	Greenville, SC	Woodruff Rd	2:05 PM	Birmingham, AL	MAX Central Station	Economy	$42	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/5/2026 8:40:00 AM to MAX Central Station, Birmingham, AL (USA) arriving at 6/5/2026 2:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 6h 25m
FlixBus	6h 10m	1:20 PM	Greenville, SC	Woodruff Rd	6:30 PM	Birmingham, AL	MAX Central Station	Economy	$42	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/5/2026 1:20:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/5/2026 6:30:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 6h 10m
FlixBus	7h 20m	7:40 PM	Greenville, SC	Woodruff Rd	2:00 AM	Birmingham, AL	MAX Central Station	Economy	$42	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/5/2026 7:40:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/6/2026 2:00:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 7h 20m
Greyhound US	7h 55m	2:45 PM	Greenville, SC	Woodruff Rd	9:40 PM	Birmingham, AL	MAX Central Station	Economy	$43	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/5/2026 2:45:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/5/2026 9:40:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 7h 55m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 25m	8:40 AM	Greenville, SC	Woodruff Rd	2:05 PM	Birmingham, AL	MAX Central Station	Economy	$43	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/6/2026 8:40:00 AM to MAX Central Station, Birmingham, AL (USA) arriving at 6/6/2026 2:05:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 25m
FlixBus	6h 10m	1:20 PM	Greenville, SC	Woodruff Rd	6:30 PM	Birmingham, AL	MAX Central Station	Economy	$43	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/6/2026 1:20:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/6/2026 6:30:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 10m
FlixBus	7h 20m	7:40 PM	Greenville, SC	Woodruff Rd	2:00 AM	Birmingham, AL	MAX Central Station	Economy	$43	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/6/2026 7:40:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/7/2026 2:00:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 7h 20m
Greyhound US	7h 55m	2:45 PM	Greenville, SC	Woodruff Rd	9:40 PM	Birmingham, AL	MAX Central Station	Economy	$43	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/6/2026 2:45:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/6/2026 9:40:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 7h 55m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 25m	8:40 AM	Greenville, SC	Woodruff Rd	2:05 PM	Birmingham, AL	MAX Central Station	Economy	$49	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/7/2026 8:40:00 AM to MAX Central Station, Birmingham, AL (USA) arriving at 6/7/2026 2:05:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 6h 25m
FlixBus	6h 10m	1:20 PM	Greenville, SC	Woodruff Rd	6:30 PM	Birmingham, AL	MAX Central Station	Economy	$49	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/7/2026 1:20:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/7/2026 6:30:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 6h 10m
FlixBus	7h 20m	7:40 PM	Greenville, SC	Woodruff Rd	2:00 AM	Birmingham, AL	MAX Central Station	Economy	$49	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/7/2026 7:40:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/8/2026 2:00:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 7h 20m
Greyhound US	7h 55m	2:45 PM	Greenville, SC	Woodruff Rd	9:40 PM	Birmingham, AL	MAX Central Station	Economy	$49	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/7/2026 2:45:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/7/2026 9:40:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 7h 55m

Did you know that if you travel from Greenville, SC to Birmingham, AL via Atlanta, GA, you can save more than $8? You can find the corresponding connections below.
- FlixBus
  
  6h 10m
  
  0
  
  1:20 PM
  
  Greenville, SC
  Woodruff Rd
  
  4:05 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $21
  
  A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/8/2026 1:20:00 PM to Garnett Transit Station, Atlanta, GA (USA) arriving at 6/8/2026 4:05:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 2h 45m
- Greyhound US
  
  2h 50m
  
  0
  
  4:40 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  6:30 PM
  
  Birmingham, AL
  MAX Central Station
  
  0
  
  Economy
  
  $20
  
  A Bus from Greyhound US goes from Garnett Transit Station, Atlanta, GA (USA) at 6/8/2026 4:40:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/8/2026 6:30:00 PM. 50 Economy ticket for $20 per person are available. Travel duration is 2h 50m
Travel time is 1h 0m longer, but you will save $8

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	6h 25m	8:40 AM	Greenville, SC	Woodruff Rd	2:05 PM	Birmingham, AL	MAX Central Station	Economy	$43	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/10/2026 8:40:00 AM to MAX Central Station, Birmingham, AL (USA) arriving at 6/10/2026 2:05:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 25m
FlixBus	6h 10m	1:20 PM	Greenville, SC	Woodruff Rd	6:30 PM	Birmingham, AL	MAX Central Station	Economy	$43	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/10/2026 1:20:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/10/2026 6:30:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 10m
Greyhound US	7h 55m	2:45 PM	Greenville, SC	Woodruff Rd	9:40 PM	Birmingham, AL	MAX Central Station	Economy	$43	A Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 6/10/2026 2:45:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/10/2026 9:40:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 7h 55m
FlixBus	10h 5m	10:00 PM	Greenville, SC	Woodruff Rd	7:05 AM	Birmingham, AL	MAX Central Station	Economy	$45	A Bus from FlixBus goes from Woodruff Rd, Greenville, SC (USA) at 6/10/2026 10:00:00 PM to MAX Central Station, Birmingham, AL (USA) arriving at 6/11/2026 7:05:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 10h 5m

Best Price Offer: The price for the cheapest bus from Greenville, SC to Birmingham, AL is $38 on 6/4/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Greenville, SC and Birmingham, AL

See here how frequent the connections between Greenville, SC and Birmingham, AL are, during different times and days of the week.

Wednesday is the busiest day, with more than 8 daily buses from Greenville, SC to Birmingham, AL. Sunday has instead the fewest connections, with only 5 daily coaches between Greenville, SC and Birmingham, AL.

The busiest time of the day is the Afternoon, with 14 buses from Greenville, SC to Birmingham, AL, while Morning sees the fewest connections between Greenville, SC and Birmingham, AL, with 7 offers.

Facts about the bus from Greenville, SC to Birmingham, AL

Compare all providers like FlixBus and Greyhound US that travel 6 times every day by bus from Greenville, SC to Birmingham, AL in one click! Book your bus ticket from Greenville, SC to Birmingham, AL starting from $38!

Cheapest Bus	$38
Fastest Bus	4h 50m
Earliest Bus	8:40 AM
Latest Bus	10:00 PM
Daily Bus Routes	6 Ø
Distance	268.9 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Greenville, SC to Birmingham, AL

Every day, 6 buses from 2 bus companies leave Greenville, SC for Birmingham, AL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/04/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/31

Monday 06/01

Tuesday 06/02

Wednesday 06/03

Thursday 06/04

$50

Friday 06/05

$42

Saturday 06/06

$43

Sunday 06/07

$49

Monday 06/08

Tuesday 06/09

Wednesday 06/10

$43

Thursday 06/11

$51

Friday 06/12

Saturday 06/13

Sunday 06/14

$49

Monday 06/15

$51

Tuesday 06/16

$52

Wednesday 06/17

$55

Thursday 06/18

$62

Friday 06/19

$57

Saturday 06/20

$58

Sunday 06/21

$55

Monday 06/22

$56

Tuesday 06/23

$48

Wednesday 06/24

Thursday 06/25

$51

Friday 06/26

Saturday 06/27

The cheapest time to travel from Greenville, SC to Birmingham, AL

See here on which day and which time of the day you can find the cheapest bus ticket from Greenville, SC to Birmingham, AL, for the next 30 days.

With a price starting from $38, Thursday is the cheapest day for a bus from Greenville, SC to Birmingham, AL. Sunday instead is the most expensive day with prices starting from $49.

Morning is the cheapest day time for bus tickets from Greenville, SC to Birmingham, AL, with $38. Evening is the most expensive time of the day with prices starting from $41.

How to save money travelling from Greenville, SC to Birmingham, AL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to Birmingham, AL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Birmingham, AL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Birmingham, AL are also emptier.

All bus stations and stops in Greenville, SC and Birmingham, AL

In the map below, you can see where to find all bus stations in Greenville, SC and Birmingham, AL.

McDonald's

Woodruff Rd 1111

Woodruff Rd

Woodruff Rd 1116

N Church St

Greyhound Bus Station

Hendrix Dr 9

Guadalajara Supermarket

White Horse Rd 2803

MAX Central Station

Morris Ave 1735

Homewood

Green Springs Hwy 22

Cahaba

7th Ave S #205 2717

Service and Comfort on the bus from Greenville, SC to Birmingham, AL

Want to know which seat classes are available on the buses from Greenville, SC to Birmingham, AL? Or which bus companies serve the route Greenville, SC to Birmingham, AL? Below you will find answers to your questions.

FAQs about the Greenville, SC to Birmingham, AL bus

How much does a Greenville, SC Birmingham, AL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $38 and takes 5h 25m to reach Birmingham, AL. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to Birmingham, AL?

This route is offered by 2 companies with a range of ticket prices between $38 and $52. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Birmingham, AL.

On average, how many connections are available from Greenville, SC to Birmingham, AL each day?

Every day, the Greenville, SC to Birmingham, AL bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to Birmingham, AL take?

The fastest bus from Greenville, SC to Birmingham, AL is offered by FlixBus and takes 4h 50m. Bus tickets for this connection cost $38. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to Birmingham, AL?

The earliest bus arriving in Birmingham, AL from Greenville, SC starts at 8:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to Birmingham, AL?

The latest bus trip departing from Greenville, SC for Birmingham, AL starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC Birmingham, AL route?

When traveling by bus from Greenville, SC to Birmingham, AL, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and Birmingham, AL?

You can check all the direct connections between Greenville, SC and Birmingham, AL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Greenville, SC to Birmingham, AL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Birmingham, AL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC Birmingham, AL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Birmingham, AL on your planned travel date.

How does CheckMyBus find the best bus deals from Greenville, SC to Birmingham, AL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Greenville, SC and Birmingham, AL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Greenville, SC to Birmingham, AL?

Prices and availability for 6 trips between Greenville, SC and Birmingham, AL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Greenville, SC to Birmingham, AL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to Birmingham, AL

Here’s an overview of the most popular bus routes to Greenville, SC and to Birmingham, AL. Simply click on the connection of your choice, and you will find all the details about your bus route!