Which bus from Greenville, SC to Syracuse, NY is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $132
Compare & Save Millions of buses in one click. Save up to 70%!
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Greenville, SC to Syracuse, NY

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Syracuse, NY from various bus operators like FlixBus or Greyhound US for the next days.

today
$168
tomorrow
Thursday
Friday
$177
Saturday
Sunday
Monday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 21h 40m 7:25 AM Greenville, SC Woodruff Rd 5:05 AM Syracuse, NY Regional Transit Center  Economy $168
Greyhound US 24h 30m 10:50 AM Greenville, SC Woodruff Rd 11:20 AM Syracuse, NY Regional Transit Center  Economy $169
FlixBus 21h 30m 10:00 PM Greenville, SC Woodruff Rd 7:30 PM Syracuse, NY Regional Transit Center  Economy $177
FlixBus 23h 0m 4:15 PM Greenville, SC Woodruff Rd 3:15 PM Syracuse, NY Regional Transit Center  Economy $184
  • Did you know that if you travel from Greenville, SC to Syracuse, NY via Washington, DC, you can save more than $20? You can find the corresponding connections below.
    • FlixBus
      21h 40m
      0
      7:25 AM
      Greenville, SC
      Woodruff Rd
      6:25 PM
      Washington, DC
      Union Station
      0
      FlixBus
      Economy
      $79
      • Waiting Time 1h 0m
    • Busbud
      9h 40m
      0
      7:25 PM
      Washington, DC
      Union Station
      5:05 AM
      Syracuse, NY
      Regional Transit Center
      0
      Busbud
      Economy
      $69
    Travel time is 0h 10m longer, but you will save $20

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 15m 12:05 PM Greenville, SC Woodruff Rd 11:20 AM Syracuse, NY Regional Transit Center  Economy $177
Greyhound US 21h 40m 7:25 AM Greenville, SC Woodruff Rd 5:05 AM Syracuse, NY Regional Transit Center  Economy $178
FlixBus 23h 0m 4:15 PM Greenville, SC Woodruff Rd 3:15 PM Syracuse, NY Regional Transit Center  Economy $194
FlixBus 21h 30m 10:00 PM Greenville, SC Woodruff Rd 7:30 PM Syracuse, NY Regional Transit Center  Economy $218
  • Did you know that if you travel from Greenville, SC to Syracuse, NY via Washington, DC, you can save more than $29? You can find the corresponding connections below.
    • FlixBus
      21h 40m
      0
      7:25 AM
      Greenville, SC
      Woodruff Rd
      6:25 PM
      Washington, DC
      Union Station
      0
      FlixBus
      Economy
      $79
      • Waiting Time 1h 0m
    • Busbud
      9h 40m
      0
      7:25 PM
      Washington, DC
      Union Station
      5:05 AM
      Syracuse, NY
      Regional Transit Center
      0
      Busbud
      Economy
      $69
    Travel time is 0h 10m longer, but you will save $29

Best Price Offer: The price for the cheapest bus from Greenville, SC to Syracuse, NY is $132 on 12/15/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Greenville, SC and Syracuse, NY

See here how frequent the connections between Greenville, SC and Syracuse, NY are, during different times and days of the week.
Tuesday is the busiest day, with more than 4 daily buses from Greenville, SC to Syracuse, NY. Tuesday has instead the fewest connections, with only 4 daily coaches between Greenville, SC and Syracuse, NY.
The busiest time of the day is the Morning, with 3 buses from Greenville, SC to Syracuse, NY, while Evening sees the fewest connections between Greenville, SC and Syracuse, NY, with 2 offers.

Facts about the bus from Greenville, SC to Syracuse, NY

Compare all providers like FlixBus and Greyhound US that travel 4 times every day by bus from Greenville, SC to Syracuse, NY in one click! Book your bus ticket from Greenville, SC to Syracuse, NY starting from $132!

Cheapest Bus $132
Fastest Bus 21h 30m
Earliest Bus 7:25 AM
Latest Bus 10:00 PM
Daily Bus Routes 4 Ø
Distance 658.2 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Greenville, SC to Syracuse, NY

Every day, 4 buses from 2 bus companies leave Greenville, SC for Syracuse, NY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/16/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/14
Monday 12/15
Tuesday 12/16
$168
Wednesday 12/17
Thursday 12/18
Friday 12/19
$177
Saturday 12/20
Sunday 12/21
Monday 12/22
Tuesday 12/23
$221
Wednesday 12/24
$220
Thursday 12/25
Friday 12/26
Saturday 12/27
Sunday 12/28
Monday 12/29
Tuesday 12/30
Wednesday 12/31
Thursday 01/01
Friday 01/02
Saturday 01/03
Sunday 01/04
Monday 01/05
Tuesday 01/06
Wednesday 01/07
Thursday 01/08
Friday 01/09
Saturday 01/10

The cheapest time to travel from Greenville, SC to Syracuse, NY

See here on which day and which time of the day you can find the cheapest bus ticket from Greenville, SC to Syracuse, NY, for the next 30 days.
With a price starting from $168, Tuesday is the cheapest day for a bus from Greenville, SC to Syracuse, NY. Friday instead is the most expensive day with prices starting from $177.
Morning is the cheapest day time for bus tickets from Greenville, SC to Syracuse, NY, with $168. Evening is the most expensive time of the day with prices starting from $177.

How to save money travelling from Greenville, SC to Syracuse, NY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to Syracuse, NY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Syracuse, NY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Syracuse, NY are also emptier.

Beloved bus companies from Greenville, SC to Syracuse, NY

These are the most booked bus companies between Greenville, SC to Syracuse, NY from our users.

Greyhound US from Greenville, SC to Syracuse, NY

Greyhound US

Here you will find the key facts about the Greyhound US bus route Greenville, SC to Syracuse, NY:

Cheapest Price $168
Fastest Bus 21h 40m
Earliest Bus 7:25 AM
Last Bus 7:25 AM
Daily Connections 1 Ø
Found on 12/11/2025

All bus stations and stops in Greenville, SC and Syracuse, NY

In the map below, you can see where to find all bus stations in Greenville, SC and Syracuse, NY.

Service and Comfort on the bus from Greenville, SC to Syracuse, NY

Want to know which seat classes are available on the buses from Greenville, SC to Syracuse, NY? Or which bus companies serve the route Greenville, SC to Syracuse, NY? Below you will find answers to your questions.

FAQs about the Greenville, SC to Syracuse, NY bus

How much does a Greenville, SC Syracuse, NY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $132 and takes 21h 40m to reach Syracuse, NY. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to Syracuse, NY?

This route is offered by 2 companies with a range of ticket prices between $132 and $218. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Syracuse, NY.

On average, how many connections are available from Greenville, SC to Syracuse, NY each day?

Every day, the Greenville, SC to Syracuse, NY bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to Syracuse, NY take?

The fastest bus from Greenville, SC to Syracuse, NY is offered by FlixBus and takes 21h 30m. Bus tickets for this connection cost $177. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to Syracuse, NY?

The earliest bus arriving in Syracuse, NY from Greenville, SC starts at 7:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to Syracuse, NY?

The latest bus trip departing from Greenville, SC for Syracuse, NY starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC Syracuse, NY route?

When traveling by bus from Greenville, SC to Syracuse, NY, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and Syracuse, NY?

You can check all the direct connections between Greenville, SC and Syracuse, NY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Greenville, SC to Syracuse, NY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Syracuse, NY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC Syracuse, NY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Syracuse, NY on your planned travel date.

How does CheckMyBus find the best bus deals from Greenville, SC to Syracuse, NY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Greenville, SC and Syracuse, NY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Greenville, SC to Syracuse, NY?

Prices and availability for 4 trips between Greenville, SC and Syracuse, NY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Greenville, SC to Syracuse, NY

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to Syracuse, NY

Here’s an overview of the most popular bus routes to Greenville, SC and to Syracuse, NY. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses from Atlanta, GA to Greenville, SC Buses from Atlanta, GA to Greenville, SC
Buses to Greenville, SC from Jacksonville, FL Buses to Greenville, SC from Jacksonville, FL
Charlotte to Greenville, SC bus Charlotte to Greenville, SC bus
Buses Houston to Greenville, SC Buses Houston to Greenville, SC
Bus New York to Syracuse, NY Bus New York to Syracuse, NY
Buses Ottawa, ON to Syracuse, NY Buses Ottawa, ON to Syracuse, NY
Bus Boston, MA to Syracuse, NY Bus Boston, MA to Syracuse, NY
Buses Newark to Syracuse, NY Buses Newark to Syracuse, NY
Popular Airport Shuttles to Greenville, SC and to Syracuse, NY
CheckMyBus › Buses in USA › Bus to Greenville, SC › Bus to Syracuse, NY

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.