Bus Mesa, AZ to Orlando, FL - Compare all Companies

Compare all timetables for the bus from Mesa, AZ to Orlando, FL

Here is a selection of the cheapest bus trips from the schedule from Mesa, AZ to Orlando, FL from various bus operators like Greyhound US for the next days.

today

$220

tomorrow

$216

Wednesday

Thursday

$217

Friday

Saturday

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	50h 0m	2:50 AM	Mesa, AZ	Greyhound	7:50 AM	Orlando, FL	Bus Station	Economy	$220	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/20/2026 2:50:00 AM to Bus Station, Orlando, FL (USA) arriving at 4/22/2026 7:50:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 50h 0m
Greyhound US	65h 40m	6:15 PM	Mesa, AZ	Greyhound	2:55 PM	Orlando, FL	Florida Mall	Economy	$220	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/20/2026 6:15:00 PM to Florida Mall, Orlando, FL (USA) arriving at 4/23/2026 2:55:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 65h 40m
Greyhound US	53h 20m	6:15 PM	Mesa, AZ	Greyhound	2:35 AM	Orlando, FL	Bus Station	Economy	$221	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/20/2026 6:15:00 PM to Bus Station, Orlando, FL (USA) arriving at 4/23/2026 2:35:00 AM. 50 Economy ticket for $221 per person are available. Travel duration is 53h 20m
Greyhound US	54h 40m	8:10 PM	Mesa, AZ	Greyhound	5:50 AM	Orlando, FL	Bus Station	Economy	$221	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/20/2026 8:10:00 PM to Bus Station, Orlando, FL (USA) arriving at 4/23/2026 5:50:00 AM. 50 Economy ticket for $221 per person are available. Travel duration is 54h 40m
Greyhound US	61h 19m	7:40 AM	Mesa, AZ	Greyhound	11:59 PM	Orlando, FL	Florida Mall	Economy	$222	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/20/2026 7:40:00 AM to Florida Mall, Orlando, FL (USA) arriving at 4/22/2026 11:59:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 61h 19m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	65h 40m	6:15 PM	Mesa, AZ	Greyhound	2:55 PM	Orlando, FL	Florida Mall	Economy	$216	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/21/2026 6:15:00 PM to Florida Mall, Orlando, FL (USA) arriving at 4/24/2026 2:55:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 65h 40m
Greyhound US	50h 0m	2:50 AM	Mesa, AZ	Greyhound	7:50 AM	Orlando, FL	Bus Station	Economy	$216	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/21/2026 2:50:00 AM to Bus Station, Orlando, FL (USA) arriving at 4/23/2026 7:50:00 AM. 50 Economy ticket for $216 per person are available. Travel duration is 50h 0m
Greyhound US	52h 35m	6:15 PM	Mesa, AZ	Greyhound	1:50 AM	Orlando, FL	Bus Station	Economy	$216	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/21/2026 6:15:00 PM to Bus Station, Orlando, FL (USA) arriving at 4/24/2026 1:50:00 AM. 50 Economy ticket for $216 per person are available. Travel duration is 52h 35m
Greyhound US	54h 40m	8:10 PM	Mesa, AZ	Greyhound	5:50 AM	Orlando, FL	Bus Station	Economy	$217	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/21/2026 8:10:00 PM to Bus Station, Orlando, FL (USA) arriving at 4/24/2026 5:50:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 54h 40m
Greyhound US	57h 5m	2:50 AM	Mesa, AZ	Greyhound	2:55 PM	Orlando, FL	Florida Mall	Economy	$218	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/21/2026 2:50:00 AM to Florida Mall, Orlando, FL (USA) arriving at 4/23/2026 2:55:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 57h 5m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	54h 40m	8:10 PM	Mesa, AZ	Greyhound	5:50 AM	Orlando, FL	Bus Station	Economy	$217	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/23/2026 8:10:00 PM to Bus Station, Orlando, FL (USA) arriving at 4/26/2026 5:50:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 54h 40m
Greyhound US	52h 35m	6:15 PM	Mesa, AZ	Greyhound	1:50 AM	Orlando, FL	Bus Station	Economy	$218	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/23/2026 6:15:00 PM to Bus Station, Orlando, FL (USA) arriving at 4/26/2026 1:50:00 AM. 50 Economy ticket for $218 per person are available. Travel duration is 52h 35m
Greyhound US	57h 5m	2:50 AM	Mesa, AZ	Greyhound	2:55 PM	Orlando, FL	Florida Mall	Economy	$218	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/23/2026 2:50:00 AM to Florida Mall, Orlando, FL (USA) arriving at 4/25/2026 2:55:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 57h 5m
Greyhound US	65h 40m	6:15 PM	Mesa, AZ	Greyhound	2:55 PM	Orlando, FL	Florida Mall	Economy	$218	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/23/2026 6:15:00 PM to Florida Mall, Orlando, FL (USA) arriving at 4/26/2026 2:55:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 65h 40m
Greyhound US	50h 0m	2:50 AM	Mesa, AZ	Greyhound	7:50 AM	Orlando, FL	Bus Station	Economy	$224	A Bus from Greyhound US goes from Greyhound, Mesa, AZ (USA) at 4/23/2026 2:50:00 AM to Bus Station, Orlando, FL (USA) arriving at 4/25/2026 7:50:00 AM. 50 Economy ticket for $224 per person are available. Travel duration is 50h 0m

Best Price Offer: The price for the cheapest bus from Mesa, AZ to Orlando, FL is $216 on 5/1/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Mesa, AZ and Orlando, FL

See here how frequent the connections between Mesa, AZ and Orlando, FL are, during different times and days of the week.

Tuesday is the busiest day, with more than 7 daily buses from Mesa, AZ to Orlando, FL. Monday has instead the fewest connections, with only 6 daily coaches between Mesa, AZ and Orlando, FL.

The busiest time of the day is the Evening, with 9 buses from Mesa, AZ to Orlando, FL, while Night sees the fewest connections between Mesa, AZ and Orlando, FL, with 5 offers.

Facts about the bus from Mesa, AZ to Orlando, FL

Compare all providers like Greyhound US that travel 6 times every day by bus from Mesa, AZ to Orlando, FL in one click! Book your bus ticket from Mesa, AZ to Orlando, FL starting from $216!

Cheapest Bus	$216
Fastest Bus	53h 0m
Earliest Bus	2:50 AM
Latest Bus	8:10 PM
Daily Bus Routes	6 Ø
Distance	1,828.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Mesa, AZ to Orlando, FL

Every day, 6 buses from 1 bus companies leave Mesa, AZ for Orlando, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$220

Tuesday 04/21

$216

Wednesday 04/22

Thursday 04/23

$217

Friday 04/24

Saturday 04/25

Sunday 04/26

Monday 04/27

$216

Tuesday 04/28

Wednesday 04/29

Thursday 04/30

Friday 05/01

$216

Saturday 05/02

Sunday 05/03

$217

Monday 05/04

$220

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

Saturday 05/09

Sunday 05/10

$222

Monday 05/11

$219

Tuesday 05/12

Wednesday 05/13

$218

Thursday 05/14

$218

Friday 05/15

$223

Saturday 05/16

The cheapest time to travel from Mesa, AZ to Orlando, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Mesa, AZ to Orlando, FL, for the next 30 days.

With a price starting from $216, Monday is the cheapest day for a bus from Mesa, AZ to Orlando, FL. Thursday instead is the most expensive day with prices starting from $217.

Night is the cheapest day time for bus tickets from Mesa, AZ to Orlando, FL, with $216. Morning is the most expensive time of the day with prices starting from $220.

How to save money travelling from Mesa, AZ to Orlando, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mesa, AZ to Orlando, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mesa, AZ to Orlando, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mesa, AZ to Orlando, FL are also emptier.

All bus stations and stops in Mesa, AZ and Orlando, FL

In the map below, you can see where to find all bus stations in Mesa, AZ and Orlando, FL.

Greyhound

S Country Club Dr 1423

Fry’s Fuel Center

W Main Street 1235

Bus Station

N John Young Pkwy 555

Florida Mall

Florida Mall Avenue 1602

RedCoach Station

Belle Isle

Universal Studio Orlando Resort

Universal Blvd 5800

Seaworld Hotels

International Dr 10100

Service and Comfort on the bus from Mesa, AZ to Orlando, FL

Want to know which seat classes are available on the buses from Mesa, AZ to Orlando, FL? Or which bus companies serve the route Mesa, AZ to Orlando, FL? Below you will find answers to your questions.

FAQs about the Mesa, AZ to Orlando, FL bus

How much does a Mesa, AZ Orlando, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $216 and takes 53h 0m to reach Orlando, FL. Compare offers to save money!

How much could I save by comparing buses from Mesa, AZ to Orlando, FL?

This route is offered by 1 companies with a range of ticket prices between $216 and $227. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Orlando, FL.

On average, how many connections are available from Mesa, AZ to Orlando, FL each day?

Every day, the Mesa, AZ to Orlando, FL bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mesa, AZ to Orlando, FL take?

The fastest bus from Mesa, AZ to Orlando, FL is offered by Greyhound US and takes 53h 0m. Bus tickets for this connection cost $220. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mesa, AZ to Orlando, FL?

The earliest bus arriving in Orlando, FL from Mesa, AZ starts at 2:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mesa, AZ to Orlando, FL?

The latest bus trip departing from Mesa, AZ for Orlando, FL starts at 8:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mesa, AZ Orlando, FL route?

When traveling by bus from Mesa, AZ to Orlando, FL, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mesa, AZ and Orlando, FL?

You can check all the direct connections between Mesa, AZ and Orlando, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mesa, AZ to Orlando, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mesa, AZ Orlando, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mesa, AZ Orlando, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mesa, AZ to Orlando, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Mesa, AZ to Orlando, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Mesa, AZ and Orlando, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mesa, AZ to Orlando, FL?

Prices and availability for 6 trips between Mesa, AZ and Orlando, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mesa, AZ to Orlando, FL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mesa, AZ and to Orlando, FL

Here’s an overview of the most popular bus routes to Mesa, AZ and to Orlando, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!