Bus Mexico City to Acayucan: Compare prices and save money

Compare all timetables for the bus from Mexico City to Acayucan

Here is a selection of the cheapest bus trips from the schedule from Mexico City to Acayucan from various bus operators like ADO, OCC or Autobuses Unidos for the next days.

today

$57

tomorrow

$57

Wednesday

$74

Thursday

Friday

$74

Saturday

Sunday

$58

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Autobuses Unidos	9h 50m	9:20 PM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	7:10 AM	Acayucan	Central Bus Station	Economy	$57	A Bus from Autobuses Unidos goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/22/2026 9:20:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/23/2026 7:10:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 9h 50m
ADO	8h 50m	12:05 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	8:55 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/22/2026 12:05:00 AM to Central Bus Station, Acayucan (Mexico) arriving at 6/22/2026 8:55:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 8h 50m
ADO	10h 0m	12:45 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	10:45 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/22/2026 12:45:00 AM to Central Bus Station, Acayucan (Mexico) arriving at 6/22/2026 10:45:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 10h 0m
OCC	8h 30m	9:05 PM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	5:35 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from OCC goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/22/2026 9:05:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/23/2026 5:35:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 8h 30m
OCC	9h 35m	8:00 PM	Mexico City	Norte Bus Station	5:35 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from OCC goes from Norte Bus Station, Mexico City (Mexico) at 6/22/2026 8:00:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/23/2026 5:35:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 9h 35m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Autobuses Unidos	9h 10m	9:20 PM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	6:30 AM	Acayucan	Central Bus Station	Economy	$57	A Bus from Autobuses Unidos goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/23/2026 9:20:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/24/2026 6:30:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 9h 10m
ADO	8h 50m	12:05 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	8:55 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/23/2026 12:05:00 AM to Central Bus Station, Acayucan (Mexico) arriving at 6/23/2026 8:55:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 8h 50m
ADO	10h 0m	12:45 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	10:45 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/23/2026 12:45:00 AM to Central Bus Station, Acayucan (Mexico) arriving at 6/23/2026 10:45:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 10h 0m
OCC	8h 30m	9:05 PM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	5:35 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from OCC goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/23/2026 9:05:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/24/2026 5:35:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 8h 30m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ADO	10h 10m	8:30 AM	Mexico City	Norte Bus Station	6:40 PM	Acayucan	Central Bus Station	Economy	$74	A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 6/24/2026 8:30:00 AM to Central Bus Station, Acayucan (Mexico) arriving at 6/24/2026 6:40:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 10h 10m
ADO	9h 10m	10:30 AM	Mexico City	Norte Bus Station	7:40 PM	Acayucan	Central Bus Station	Economy	$74	A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 6/24/2026 10:30:00 AM to Central Bus Station, Acayucan (Mexico) arriving at 6/24/2026 7:40:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 9h 10m
ADO	7h 30m	10:15 PM	Mexico City	Norte Bus Station	5:45 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from ADO goes from Norte Bus Station, Mexico City (Mexico) at 6/24/2026 10:15:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/25/2026 5:45:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 7h 30m
OCC	9h 35m	8:00 PM	Mexico City	Norte Bus Station	5:35 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from OCC goes from Norte Bus Station, Mexico City (Mexico) at 6/24/2026 8:00:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/25/2026 5:35:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 9h 35m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ADO	8h 50m	12:05 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	8:55 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/26/2026 12:05:00 AM to Central Bus Station, Acayucan (Mexico) arriving at 6/26/2026 8:55:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 8h 50m
ADO	10h 0m	12:45 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	10:45 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/26/2026 12:45:00 AM to Central Bus Station, Acayucan (Mexico) arriving at 6/26/2026 10:45:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 10h 0m
ADO	8h 10m	9:35 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	5:45 PM	Acayucan	Central Bus Station	Economy	$74	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/26/2026 9:35:00 AM to Central Bus Station, Acayucan (Mexico) arriving at 6/26/2026 5:45:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 8h 10m
OCC	8h 30m	9:05 PM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	5:35 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from OCC goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/26/2026 9:05:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/27/2026 5:35:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 8h 30m
OCC	9h 35m	8:00 PM	Mexico City	Norte Bus Station	5:35 AM	Acayucan	Central Bus Station	Economy	$74	A Bus from OCC goes from Norte Bus Station, Mexico City (Mexico) at 6/26/2026 8:00:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/27/2026 5:35:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 9h 35m

Did you know that if you travel from Mexico City to Acayucan via Puebla City, PL, you can save more than $7? You can find the corresponding connections below.
- Flix Mexico
  
  11h 30m
  
  0
  
  6:45 PM
  
  Mexico City
  Fórum Buenavista
  
  10:20 PM
  
  Puebla City, PL
  Central Bus Station (CAPU)
  
  0
  
  Economy
  
  $11
  
  A Bus from Flix Mexico goes from Fórum Buenavista, Mexico City (Mexico) at 6/25/2026 6:45:00 PM to Central Bus Station (CAPU), Puebla City, PL (Mexico) arriving at 6/25/2026 10:20:00 PM. 50 Economy ticket for $11 per person are available. Travel duration is 3h 35m
- Autobuses Unidos
  
  7h 30m
  
  0
  
  10:45 PM
  
  Puebla City, PL
  Central Bus Station (CAPU)
  
  6:15 AM
  
  Acayucan
  Central Bus Station
  
  0
  
  Economy
  
  $56
  
  A Bus from Autobuses Unidos goes from Central Bus Station (CAPU), Puebla City, PL (Mexico) at 6/25/2026 10:45:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/26/2026 6:15:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 7h 30m
Travel time is 3h 20m longer, but you will save $7

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Autobuses Unidos	9h 10m	9:20 PM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	6:30 AM	Acayucan	Central Bus Station	Economy	$58	A Bus from Autobuses Unidos goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/28/2026 9:20:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/29/2026 6:30:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 9h 10m
ADO	8h 50m	12:05 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	8:55 AM	Acayucan	Central Bus Station	Economy	$75	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/28/2026 12:05:00 AM to Central Bus Station, Acayucan (Mexico) arriving at 6/28/2026 8:55:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 8h 50m
ADO	10h 0m	12:45 AM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	10:45 AM	Acayucan	Central Bus Station	Economy	$75	A Bus from ADO goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/28/2026 12:45:00 AM to Central Bus Station, Acayucan (Mexico) arriving at 6/28/2026 10:45:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 10h 0m
OCC	8h 10m	9:05 PM	Mexico City	Terminal de Autobuses de Oriente (TAPO)	5:15 AM	Acayucan	Central Bus Station	Economy	$75	A Bus from OCC goes from Terminal de Autobuses de Oriente (TAPO), Mexico City (Mexico) at 6/28/2026 9:05:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/29/2026 5:15:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 8h 10m
OCC	9h 15m	8:00 PM	Mexico City	Norte Bus Station	5:15 AM	Acayucan	Central Bus Station	Economy	$75	A Bus from OCC goes from Norte Bus Station, Mexico City (Mexico) at 6/28/2026 8:00:00 PM to Central Bus Station, Acayucan (Mexico) arriving at 6/29/2026 5:15:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 9h 15m

Best Price Offer: The price for the cheapest bus from Mexico City to Acayucan is $57 on 6/22/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Mexico City and Acayucan

See here how frequent the connections between Mexico City and Acayucan are, during different times and days of the week.

Monday is the busiest day, with more than 32 daily buses from Mexico City to Acayucan. Wednesday has instead the fewest connections, with only 5 daily coaches between Mexico City and Acayucan.

The busiest time of the day is the Evening, with 54 buses from Mexico City to Acayucan, while Afternoon sees the fewest connections between Mexico City and Acayucan, with 8 offers.

Facts about the bus from Mexico City to Acayucan

Compare all providers like ADO, OCC and Autobuses Unidos that travel 19 times every day by bus from Mexico City to Acayucan in one click! Book your bus ticket from Mexico City to Acayucan starting from $57!

Cheapest Bus	$57
Fastest Bus	7h 10m
Earliest Bus	12:05 AM
Latest Bus	11:30 PM
Daily Bus Routes	19 Ø
Distance	294.6 miles
Bus Companies	ADO, OCC and Autobuses Unidos

Cheapest bus connections from Mexico City to Acayucan

Every day, 19 buses from 3 bus companies leave Mexico City for Acayucan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/21

Monday 06/22

$57

Tuesday 06/23

$57

Wednesday 06/24

$74

Thursday 06/25

Friday 06/26

$74

Saturday 06/27

Sunday 06/28

$58

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

Friday 07/10

$75

Saturday 07/11

$58

Sunday 07/12

$58

Monday 07/13

Tuesday 07/14

$57

Wednesday 07/15

$59

Thursday 07/16

$74

Friday 07/17

$76

Saturday 07/18

The cheapest time to travel from Mexico City to Acayucan

See here on which day and which time of the day you can find the cheapest bus ticket from Mexico City to Acayucan, for the next 30 days.

With a price starting from $57, Monday is the cheapest day for a bus from Mexico City to Acayucan. Friday instead is the most expensive day with prices starting from $74.

Evening is the cheapest day time for bus tickets from Mexico City to Acayucan, with $57. Morning is the most expensive time of the day with prices starting from $74.

How to save money travelling from Mexico City to Acayucan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mexico City to Acayucan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mexico City to Acayucan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mexico City to Acayucan are also emptier.

Beloved bus companies from Mexico City to Acayucan

These are the most booked bus companies between Mexico City to Acayucan from our users.

ADO from Mexico City to Acayucan

Here you will find the key facts about the ADO bus route Mexico City to Acayucan:

Cheapest Price	$74
Fastest Bus	7h 10m
Earliest Bus	12:05 AM
Last Bus	11:30 PM
Daily Connections	15 Ø
Found on	6/22/2026

All bus stations and stops in Mexico City and Acayucan

In the map below, you can see where to find all bus stations in Mexico City and Acayucan.

Terminal de Autobuses de Oriente (TAPO)

Calz. Ignacio Zaragoza 200

Terminal del Sur

Av. Taxqueña 1320

Observatorio Central Bus Station

Av Río de Tacubaya 122 232

Eje Central Bus Stop

Avenida Lázaro Cárdenas & Calle Poniente 112 Avenida Lázaro Cárdenas & Calle Poniente 112

Moctezuma Bus Stop

Ampliación 7 de Julio

Central Bus Station

Calle Manuel Acuña

Service and Comfort on the bus from Mexico City to Acayucan

Want to know which seat classes are available on the buses from Mexico City to Acayucan? Or which bus companies serve the route Mexico City to Acayucan? Below you will find answers to your questions.

FAQs about the Mexico City to Acayucan bus

How much does a Mexico City Acayucan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $57 and takes 9h 50m to reach Acayucan. Compare offers to save money!

How much could I save by comparing buses from Mexico City to Acayucan?

This route is offered by 3 companies with a range of ticket prices between $57 and $93. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Acayucan.

On average, how many connections are available from Mexico City to Acayucan each day?

Every day, the Mexico City to Acayucan bus route is served by approximately 19 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mexico City to Acayucan take?

The fastest bus from Mexico City to Acayucan is offered by ADO and takes 7h 10m. Bus tickets for this connection cost $91. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mexico City to Acayucan?

The earliest bus arriving in Acayucan from Mexico City starts at 12:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mexico City to Acayucan?

The latest bus trip departing from Mexico City for Acayucan starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mexico City Acayucan route?

When traveling by bus from Mexico City to Acayucan, passengers can travel with ADO, OCC and Autobuses Unidos. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mexico City and Acayucan?

You can check all the direct connections between Mexico City and Acayucan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ADO, OCC and Autobuses Unidos.

What can I take with me on the Mexico City to Acayucan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mexico City Acayucan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mexico City Acayucan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mexico City to Acayucan on your planned travel date.

How does CheckMyBus find the best bus deals from Mexico City to Acayucan?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 19 daily trips between Mexico City and Acayucan. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mexico City to Acayucan?

Prices and availability for 19 trips between Mexico City and Acayucan change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mexico City to Acayucan

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mexico City and to Acayucan

Here’s an overview of the most popular bus routes to Mexico City and to Acayucan. Simply click on the connection of your choice, and you will find all the details about your bus route!