Bus Mezcales to Santiago de Queretaro

Compare all timetables for the bus from Mezcales to Santiago de Queretaro

Here is a selection of the cheapest bus trips from the schedule from Mezcales to Santiago de Queretaro from various bus operators like Futura, ETN Autobuses or Primera Plus for the next days.

today

$102

tomorrow

$108

Monday

$102

Tuesday

$100

Wednesday

$100

Thursday

$100

Friday

$100

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	10h 0m	10:30 PM	Mezcales	Primera Plus	8:30 AM	Santiago de Queretaro	Bus Station	Economy	$102	A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/13/2025 10:30:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/14/2025 8:30:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 10h 0m
Futura	10h 50m	1:45 PM	Mezcales	Primera Plus	1:35 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/13/2025 1:45:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/14/2025 1:35:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 10h 50m
ETN Autobuses	9h 40m	2:10 PM	Mezcales	Vallarte Plus	11:50 PM	Santiago de Queretaro	Bus Station	Premium Economy	$143	A Bus from ETN Autobuses goes from Vallarte Plus, Mezcales (Mexico) at 12/13/2025 2:10:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/13/2025 11:50:00 PM. 50 Premium Economy ticket for $143 per person are available. Travel duration is 9h 40m
Transportes Chihuahuenses	31h 0m	12:15 PM	Mezcales	Primera Plus	8:15 PM	Santiago de Queretaro	Bus Station	Economy	$179	A Bus from Transportes Chihuahuenses goes from Primera Plus, Mezcales (Mexico) at 12/13/2025 12:15:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/14/2025 8:15:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 31h 0m
Elite	31h 40m	7:00 PM	Mezcales	Primera Plus	3:40 AM	Santiago de Queretaro	Bus Station	Economy	$179	A Bus from Elite goes from Primera Plus, Mezcales (Mexico) at 12/13/2025 7:00:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/15/2025 3:40:00 AM. 50 Economy ticket for $179 per person are available. Travel duration is 31h 40m

Did you know that if you travel from Mezcales to Santiago de Queretaro via Guadalajara, JC, you can save more than $19? You can find the corresponding connections below.
- Primera Plus
  
  10h 25m
  
  0
  
  3:50 PM
  
  Mezcales
  Vallarte Plus
  
  8:20 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  0
  
  Economy
  
  $49
  
  A Bus from Primera Plus goes from Vallarte Plus, Mezcales (Mexico) at 12/14/2025 3:50:00 PM to Central de Autobuses, Guadalajara, JC (Mexico) arriving at 12/14/2025 8:20:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 4h 30m
- Busbud
  
  4h 30m
  
  0
  
  9:45 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  2:15 AM
  
  Santiago de Queretaro
  Bus Station
  
  0
  
  Economy
  
  $34
  
  A Bus from Busbud goes from Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) at 12/14/2025 9:45:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/15/2025 2:15:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 4h 30m
Travel time is 0h 45m longer, but you will save $19

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Futura	11h 50m	1:45 PM	Mezcales	Primera Plus	1:35 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/14/2025 1:45:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/15/2025 1:35:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 50m
Futura	11h 25m	8:15 PM	Mezcales	Primera Plus	7:40 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/14/2025 8:15:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/15/2025 7:40:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 25m
ETN Autobuses	9h 40m	2:10 PM	Mezcales	Vallarte Plus	11:50 PM	Santiago de Queretaro	Bus Station	Premium Economy	$143	A Bus from ETN Autobuses goes from Vallarte Plus, Mezcales (Mexico) at 12/14/2025 2:10:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/14/2025 11:50:00 PM. 50 Premium Economy ticket for $143 per person are available. Travel duration is 9h 40m
ETN Autobuses	10h 10m	11:35 PM	Mezcales	Vallarte Plus	9:45 AM	Santiago de Queretaro	Bus Station	Premium Economy	$143	A Bus from ETN Autobuses goes from Vallarte Plus, Mezcales (Mexico) at 12/14/2025 11:35:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/15/2025 9:45:00 AM. 50 Premium Economy ticket for $143 per person are available. Travel duration is 10h 10m

Did you know that if you travel from Mezcales to Santiago de Queretaro via Guadalajara, JC, you can save more than $25? You can find the corresponding connections below.
- Primera Plus
  
  10h 25m
  
  0
  
  3:50 PM
  
  Mezcales
  Vallarte Plus
  
  8:20 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  0
  
  Economy
  
  $49
  
  A Bus from Primera Plus goes from Vallarte Plus, Mezcales (Mexico) at 12/14/2025 3:50:00 PM to Central de Autobuses, Guadalajara, JC (Mexico) arriving at 12/14/2025 8:20:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 4h 30m
- Busbud
  
  4h 30m
  
  0
  
  9:45 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  2:15 AM
  
  Santiago de Queretaro
  Bus Station
  
  0
  
  Economy
  
  $34
  
  A Bus from Busbud goes from Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) at 12/14/2025 9:45:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/15/2025 2:15:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 4h 30m
Travel time is 0h 45m longer, but you will save $25

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	10h 0m	10:30 PM	Mezcales	Primera Plus	8:30 AM	Santiago de Queretaro	Bus Station	Economy	$102	A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/15/2025 10:30:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/16/2025 8:30:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 10h 0m
Futura	11h 50m	1:45 PM	Mezcales	Primera Plus	1:35 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/15/2025 1:45:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/16/2025 1:35:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 50m
Futura	11h 25m	8:15 PM	Mezcales	Primera Plus	7:40 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/15/2025 8:15:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/16/2025 7:40:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 25m
ETN Autobuses	9h 40m	2:10 PM	Mezcales	Vallarte Plus	11:50 PM	Santiago de Queretaro	Bus Station	Premium Economy	$142	A Bus from ETN Autobuses goes from Vallarte Plus, Mezcales (Mexico) at 12/15/2025 2:10:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/15/2025 11:50:00 PM. 50 Premium Economy ticket for $142 per person are available. Travel duration is 9h 40m
ETN Autobuses	10h 10m	11:35 PM	Mezcales	Vallarte Plus	9:45 AM	Santiago de Queretaro	Bus Station	Premium Economy	$142	A Bus from ETN Autobuses goes from Vallarte Plus, Mezcales (Mexico) at 12/15/2025 11:35:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/16/2025 9:45:00 AM. 50 Premium Economy ticket for $142 per person are available. Travel duration is 10h 10m

Did you know that if you travel from Mezcales to Santiago de Queretaro via Guadalajara, JC, you can save more than $19? You can find the corresponding connections below.
- Primera Plus
  
  10h 25m
  
  0
  
  3:50 PM
  
  Mezcales
  Vallarte Plus
  
  8:20 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  0
  
  Economy
  
  $49
  
  A Bus from Primera Plus goes from Vallarte Plus, Mezcales (Mexico) at 12/14/2025 3:50:00 PM to Central de Autobuses, Guadalajara, JC (Mexico) arriving at 12/14/2025 8:20:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 4h 30m
- Busbud
  
  4h 30m
  
  0
  
  9:45 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  2:15 AM
  
  Santiago de Queretaro
  Bus Station
  
  0
  
  Economy
  
  $34
  
  A Bus from Busbud goes from Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) at 12/14/2025 9:45:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/15/2025 2:15:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 4h 30m
Travel time is 0h 45m longer, but you will save $19

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	9h 40m	2:10 PM	Mezcales	Primera Plus	11:50 PM	Santiago de Queretaro	Bus Station	Economy	$100	A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/16/2025 2:10:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/16/2025 11:50:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 9h 40m
Primera Plus	9h 30m	10:30 PM	Mezcales	Primera Plus	8:00 AM	Santiago de Queretaro	Bus Station	Economy	$100	A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/16/2025 10:30:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/17/2025 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 9h 30m
Futura	11h 50m	1:45 PM	Mezcales	Primera Plus	1:35 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/16/2025 1:45:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/17/2025 1:35:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 50m
Futura	11h 25m	8:15 PM	Mezcales	Primera Plus	7:40 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/16/2025 8:15:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/17/2025 7:40:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 25m
ETN Autobuses	10h 10m	11:35 PM	Mezcales	Vallarte Plus	9:45 AM	Santiago de Queretaro	Bus Station	Premium Economy	$143	A Bus from ETN Autobuses goes from Vallarte Plus, Mezcales (Mexico) at 12/16/2025 11:35:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/17/2025 9:45:00 AM. 50 Premium Economy ticket for $143 per person are available. Travel duration is 10h 10m

Did you know that if you travel from Mezcales to Santiago de Queretaro via Guadalajara, JC, you can save more than $26? You can find the corresponding connections below.
- Primera Plus
  
  11h 45m
  
  0
  
  1:35 PM
  
  Mezcales
  Primera Plus
  
  5:50 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  0
  
  Economy
  
  $49
  
  A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/17/2025 1:35:00 PM to Central de Autobuses, Guadalajara, JC (Mexico) arriving at 12/17/2025 5:50:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 4h 15m
- Busbud
  
  5h 20m
  
  0
  
  8:00 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  1:20 AM
  
  Santiago de Queretaro
  5 de Febrero Acceso a Plaza Galerías Bus Stop
  
  0
  
  Premium Economy
  
  $25
  
  A Bus from Busbud goes from Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) at 12/17/2025 8:00:00 PM to 5 de Febrero Acceso a Plaza Galerías Bus Stop, Santiago de Queretaro (Mexico) arriving at 12/18/2025 1:20:00 AM. 50 Premium Economy ticket for $25 per person are available. Travel duration is 5h 20m
Travel time is 2h 15m longer, but you will save $26

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	9h 40m	2:10 PM	Mezcales	Primera Plus	11:50 PM	Santiago de Queretaro	Bus Station	Economy	$100	A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/17/2025 2:10:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/17/2025 11:50:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 9h 40m
Primera Plus	9h 30m	10:30 PM	Mezcales	Primera Plus	8:00 AM	Santiago de Queretaro	Bus Station	Economy	$100	A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/17/2025 10:30:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/18/2025 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 9h 30m
Futura	11h 50m	1:45 PM	Mezcales	Primera Plus	1:35 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/17/2025 1:45:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/18/2025 1:35:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 50m
Futura	11h 25m	8:15 PM	Mezcales	Primera Plus	7:40 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/17/2025 8:15:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/18/2025 7:40:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 25m
ETN Autobuses	10h 10m	11:35 PM	Mezcales	Vallarte Plus	9:45 AM	Santiago de Queretaro	Bus Station	Premium Economy	$143	A Bus from ETN Autobuses goes from Vallarte Plus, Mezcales (Mexico) at 12/17/2025 11:35:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/18/2025 9:45:00 AM. 50 Premium Economy ticket for $143 per person are available. Travel duration is 10h 10m

Did you know that if you travel from Mezcales to Santiago de Queretaro via Guadalajara, JC, you can save more than $26? You can find the corresponding connections below.
- Primera Plus
  
  11h 45m
  
  0
  
  1:35 PM
  
  Mezcales
  Primera Plus
  
  5:50 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  0
  
  Economy
  
  $49
  
  A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/17/2025 1:35:00 PM to Central de Autobuses, Guadalajara, JC (Mexico) arriving at 12/17/2025 5:50:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 4h 15m
- Busbud
  
  5h 20m
  
  0
  
  8:00 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  1:20 AM
  
  Santiago de Queretaro
  5 de Febrero Acceso a Plaza Galerías Bus Stop
  
  0
  
  Premium Economy
  
  $25
  
  A Bus from Busbud goes from Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) at 12/17/2025 8:00:00 PM to 5 de Febrero Acceso a Plaza Galerías Bus Stop, Santiago de Queretaro (Mexico) arriving at 12/18/2025 1:20:00 AM. 50 Premium Economy ticket for $25 per person are available. Travel duration is 5h 20m
Travel time is 2h 15m longer, but you will save $26

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	9h 40m	2:10 PM	Mezcales	Primera Plus	11:50 PM	Santiago de Queretaro	Bus Station	Economy	$100	A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/18/2025 2:10:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/18/2025 11:50:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 9h 40m
Primera Plus	9h 30m	10:30 PM	Mezcales	Primera Plus	8:00 AM	Santiago de Queretaro	Bus Station	Economy	$100	A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/18/2025 10:30:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/19/2025 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 9h 30m
Futura	11h 50m	1:45 PM	Mezcales	Primera Plus	1:35 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/18/2025 1:45:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/19/2025 1:35:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 50m
Futura	11h 25m	8:15 PM	Mezcales	Primera Plus	7:40 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/18/2025 8:15:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/19/2025 7:40:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 25m
ETN Autobuses	10h 10m	11:35 PM	Mezcales	Vallarte Plus	9:45 AM	Santiago de Queretaro	Bus Station	Premium Economy	$144	A Bus from ETN Autobuses goes from Vallarte Plus, Mezcales (Mexico) at 12/18/2025 11:35:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/19/2025 9:45:00 AM. 50 Premium Economy ticket for $144 per person are available. Travel duration is 10h 10m

Did you know that if you travel from Mezcales to Santiago de Queretaro via Guadalajara, JC, you can save more than $26? You can find the corresponding connections below.
- Primera Plus
  
  11h 45m
  
  0
  
  1:35 PM
  
  Mezcales
  Primera Plus
  
  5:50 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  0
  
  Economy
  
  $49
  
  A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/17/2025 1:35:00 PM to Central de Autobuses, Guadalajara, JC (Mexico) arriving at 12/17/2025 5:50:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 4h 15m
- Busbud
  
  5h 20m
  
  0
  
  8:00 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  1:20 AM
  
  Santiago de Queretaro
  5 de Febrero Acceso a Plaza Galerías Bus Stop
  
  0
  
  Premium Economy
  
  $25
  
  A Bus from Busbud goes from Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) at 12/17/2025 8:00:00 PM to 5 de Febrero Acceso a Plaza Galerías Bus Stop, Santiago de Queretaro (Mexico) arriving at 12/18/2025 1:20:00 AM. 50 Premium Economy ticket for $25 per person are available. Travel duration is 5h 20m
Travel time is 2h 15m longer, but you will save $26

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Primera Plus	9h 40m	2:10 PM	Mezcales	Primera Plus	11:50 PM	Santiago de Queretaro	Bus Station	Economy	$100	A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/19/2025 2:10:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/19/2025 11:50:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 9h 40m
Primera Plus	9h 30m	10:30 PM	Mezcales	Primera Plus	8:00 AM	Santiago de Queretaro	Bus Station	Economy	$100	A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/19/2025 10:30:00 PM to Bus Station, Santiago de Queretaro (Mexico) arriving at 12/20/2025 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 9h 30m
Futura	11h 50m	1:45 PM	Mezcales	Primera Plus	1:35 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/19/2025 1:45:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/20/2025 1:35:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 50m
Futura	11h 25m	8:15 PM	Mezcales	Primera Plus	7:40 AM	Santiago de Queretaro	Terminal Norte	Economy	$108	A Bus from Futura goes from Primera Plus, Mezcales (Mexico) at 12/19/2025 8:15:00 PM to Terminal Norte, Santiago de Queretaro (Mexico) arriving at 12/20/2025 7:40:00 AM. 50 Economy ticket for $108 per person are available. Travel duration is 11h 25m

Did you know that if you travel from Mezcales to Santiago de Queretaro via Guadalajara, JC, you can save more than $26? You can find the corresponding connections below.
- Primera Plus
  
  11h 45m
  
  0
  
  1:35 PM
  
  Mezcales
  Primera Plus
  
  5:50 PM
  
  Guadalajara, JC
  Central de Autobuses
  
  0
  
  Economy
  
  $49
  
  A Bus from Primera Plus goes from Primera Plus, Mezcales (Mexico) at 12/17/2025 1:35:00 PM to Central de Autobuses, Guadalajara, JC (Mexico) arriving at 12/17/2025 5:50:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 4h 15m
- Busbud
  
  5h 20m
  
  0
  
  8:00 PM
  
  Guadalajara, JC
  Avenida de las Torres Bus Station
  
  1:20 AM
  
  Santiago de Queretaro
  5 de Febrero Acceso a Plaza Galerías Bus Stop
  
  0
  
  Premium Economy
  
  $25
  
  A Bus from Busbud goes from Avenida de las Torres Bus Station, Guadalajara, JC (Mexico) at 12/17/2025 8:00:00 PM to 5 de Febrero Acceso a Plaza Galerías Bus Stop, Santiago de Queretaro (Mexico) arriving at 12/18/2025 1:20:00 AM. 50 Premium Economy ticket for $25 per person are available. Travel duration is 5h 20m
Travel time is 2h 15m longer, but you will save $26

Best Price Offer: The price for the cheapest bus from Mezcales to Santiago de Queretaro is $100 on 12/10/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Mezcales and Santiago de Queretaro

See here how frequent the connections between Mezcales and Santiago de Queretaro are, during different times and days of the week.

Saturday is the busiest day, with more than 8 daily buses from Mezcales to Santiago de Queretaro. Sunday has instead the fewest connections, with only 4 daily coaches between Mezcales and Santiago de Queretaro.

The busiest time of the day is the Evening, with 20 buses from Mezcales to Santiago de Queretaro, while Afternoon sees the fewest connections between Mezcales and Santiago de Queretaro, with 19 offers.

Facts about the bus from Mezcales to Santiago de Queretaro

Compare all providers like Futura, ETN Autobuses and Primera Plus that travel 5 times every day by bus from Mezcales to Santiago de Queretaro in one click! Book your bus ticket from Mezcales to Santiago de Queretaro starting from $100!

Cheapest Bus	$100
Fastest Bus	9h 30m
Earliest Bus	12:15 PM
Latest Bus	10:30 PM
Daily Bus Routes	5 Ø
Distance	318.5 miles
Bus Companies	Futura, ETN Autobuses, Primera Plus, Transportes Chihuahuenses and Elite

Cheapest bus connections from Mezcales to Santiago de Queretaro

Every day, 5 buses from 5 bus companies leave Mezcales for Santiago de Queretaro: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/13/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/07

Monday 12/08

Tuesday 12/09

Wednesday 12/10

Thursday 12/11

Friday 12/12

Saturday 12/13

$143

Sunday 12/14

$108

Monday 12/15

$108

Tuesday 12/16

$100

Wednesday 12/17

$108

Thursday 12/18

$100

Friday 12/19

$100

Saturday 12/20

$100

Sunday 12/21

$100

Monday 12/22

$100

Tuesday 12/23

$100

Wednesday 12/24

$108

Thursday 12/25

$108

Friday 12/26

$100

Saturday 12/27

$100

Sunday 12/28

$100

Monday 12/29

$100

Tuesday 12/30

$100

Wednesday 12/31

$108

Thursday 01/01

$100

Friday 01/02

$108

Saturday 01/03

The cheapest time to travel from Mezcales to Santiago de Queretaro

See here on which day and which time of the day you can find the cheapest bus ticket from Mezcales to Santiago de Queretaro, for the next 30 days.

With a price starting from $100, Tuesday is the cheapest day for a bus from Mezcales to Santiago de Queretaro. Sunday instead is the most expensive day with prices starting from $100.

Afternoon is the cheapest day time for bus tickets from Mezcales to Santiago de Queretaro, with $100. Afternoon is the most expensive time of the day with prices starting from $100.

How to save money travelling from Mezcales to Santiago de Queretaro

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mezcales to Santiago de Queretaro in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mezcales to Santiago de Queretaro, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mezcales to Santiago de Queretaro are also emptier.

All bus stations and stops in Mezcales and Santiago de Queretaro

In the map below, you can see where to find all bus stations in Mezcales and Santiago de Queretaro.

Primera Plus

Blvrd Riviera Nayarit 171

Bus Station

Terminal de Autobuses

Centro Comercial Galeria

Prolongación Avenida Zaragoza 61

Terminal Norte

Av. 5 de Febrero 1400

El Colorado

Walmart Juriquilla

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mezcales to Santiago de Queretaro? Compare all modes of transports from Mezcales to Santiago de Queretaro.

Service and Comfort on the bus from Mezcales to Santiago de Queretaro

Want to know which seat classes are available on the buses from Mezcales to Santiago de Queretaro? Or which bus companies serve the route Mezcales to Santiago de Queretaro? Below you will find answers to your questions.

FAQs about the Mezcales to Santiago de Queretaro bus

How much does a Mezcales Santiago de Queretaro bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $100 and takes 9h 40m to reach Santiago de Queretaro. Compare offers to save money!

How much could I save by comparing buses from Mezcales to Santiago de Queretaro?

This route is offered by 5 companies with a range of ticket prices between $100 and $179. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santiago de Queretaro.

On average, how many connections are available from Mezcales to Santiago de Queretaro each day?

Every day, the Mezcales to Santiago de Queretaro bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mezcales to Santiago de Queretaro take?

The fastest bus from Mezcales to Santiago de Queretaro is offered by Primera Plus and takes 9h 30m. Bus tickets for this connection cost $100. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mezcales to Santiago de Queretaro?

The earliest bus arriving in Santiago de Queretaro from Mezcales starts at 12:15 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mezcales to Santiago de Queretaro?

The latest bus trip departing from Mezcales for Santiago de Queretaro starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mezcales Santiago de Queretaro route?

When traveling by bus from Mezcales to Santiago de Queretaro, passengers can travel with Futura, ETN Autobuses and Primera Plus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mezcales and Santiago de Queretaro?

You can check all the direct connections between Mezcales and Santiago de Queretaro by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Futura, ETN Autobuses and Primera Plus.

What can I take with me on the Mezcales to Santiago de Queretaro bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mezcales Santiago de Queretaro bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mezcales Santiago de Queretaro bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mezcales to Santiago de Queretaro on your planned travel date.

How does CheckMyBus find the best bus deals from Mezcales to Santiago de Queretaro?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Mezcales and Santiago de Queretaro. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mezcales to Santiago de Queretaro?

Prices and availability for 5 trips between Mezcales and Santiago de Queretaro change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mezcales to Santiago de Queretaro

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Mezcales and to Santiago de Queretaro

Here’s an overview of the most popular bus routes to Mezcales and to Santiago de Queretaro. Simply click on the connection of your choice, and you will find all the details about your bus route!